We narrowed to 148 results for: lenti crispr

1. Mouse Brie kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

   Pooled Library

   #75316

   Purpose

   Mouse sgRNA library in backbone lentiGuide-Puro targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

2. MYC-CRISPR

   Pooled Library

   #173195

   Purpose

   This pooled lentiviral CRISPR knockout library targets E-boxes genome-wide and can be applied for identification of essential MYC binding sites in a wide range of human cells.

   Depositor

   Agnieszka Dzikiewicz-Krawczyk

   Article

   Kazimierska et al Mol Oncol. 2023 Nov;17(11):2295-2313. do

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 11, 2021

   Availability

   Academic Institutions and Nonprofits only

3. Glycogene CRISPR Library

   Pooled Library

   #140961

   Purpose

   Targets human genes involved in cellular glycosylation.

   Depositor

   Sriram Neelamegham

   Article

   Zhu et al Glycobiology. 2020 Aug 8. pii: 5889976.

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 9, 2020

   Availability

   Academic Institutions and Nonprofits only

4. The Human Druggable CRISPR library

   Pooled Library

   #200013

   Purpose

   The library contains ~10,000 sgRNAs targeting 1,980 human genes (5 sgRNAs per gene and 100 nontargeting control sgRNAs).

   Depositor

   Lianxin Liu

   Article

   Zheng et al Adv Sci (Weinh). 2023 Aug;10(22):e220679

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   May 9, 2023

   Availability

   Academic Institutions and Nonprofits only

5. Human Metabolic Gene CRISPRa sgRNA library

   Pooled Library

   #187080

   Purpose

   Lentiviral CRISPRa library targeting human metabolic genes for activation of gene expression

   Depositor

   Kivanc Birsoy

   Article

   Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   Oct. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

6. Mouse Metabolic Gene CRISPRa sgRNA library

   Pooled Library

   #187081

   Purpose

   Lentiviral CRISPRa library targeting mouse metabolic genes for activation of gene expression

   Depositor

   Kivanc Birsoy

   Article

   Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   Lentiviral

   Available since

   Oct. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

7. LV2btCRISPRko.v1

   Pooled Library

   #213927

   Purpose

   Uses lentivirus to deliver the library into hard-to-transduce cells

   Depositor

   Wenfang Spring Tan

   Article

   Tan et al PLoS Pathog. 2023 Dec 6;19(12):e1011822.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   April 9, 2024

   Availability

   Academic Institutions and Nonprofits only

8. Mouse Liver CRISPR Knockout Library

   Pooled Library

   #192824

   Purpose

   CRISPR screening library containing ~72,000 sgRNAs

   Depositor

   Kristin Knouse

   Article

   Keys et al Cell Genom. 2022 Dec 14;2(12):100217. do

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   Dec. 1, 2022

   Availability

   Academic Institutions and Nonprofits only

9. Human CRISPR Metabolic Gene Knockout Library

   Pooled Library

   #110066

   Purpose

   Encodes gRNAs for targeting metabolic genes in CRISPR screens.

   Depositor

   David Sabatini

   Article

   Birsoy et al Cell. 2015 Jul 30;162(3):540-51. doi: 10

   Use

   Lentiviral

   Available since

   May 4, 2018

   Availability

   Academic Institutions and Nonprofits only

10. Human ubiquitination-related proteins CRISPR KO library

    Pooled Library

    #174592

    Purpose

    CRISPR Cas9 KO library targets 660 ubiquitination-related proteins, including all major E1, E2, E3 and deubiquitinating enzymes, as well as other ubiquitination-related proteins.

    Depositor

    Juan Bonifacino

    Article

    Jia et al Elife. 2019 Nov 6;8. pii: 50034. doi: 10

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Nov. 30, 2021

    Availability

    Academic Institutions and Nonprofits only

11. Human CRISPR Poison Exon Knockout Library

    Pooled Library

    #138084

    Purpose

    The human pgPoison library induces skipping of “poison” cassette exons and corresponding upstream constitutive exons by targeting 3' splice sites with paired gRNAs (pgRNAs).

    Depositor

    Robert Bradley

    Article

    Thomas et al Nat Genet. 2020 Jan;52(1):84-94. doi: 10

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    March 6, 2020

    Availability

    Academic Institutions and Nonprofits only

12. RNA-binding protein pooled CRISPR knockout library

    Pooled Library

    #141438

    Purpose

    CRISPR knockout library targets RBPs with 10 sgRNAs/gene

    Depositor

    Eugene Yeo

    Article

    Wheeler et al Nat Methods. 2020 May 11. pii: 10.1038/s

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    May 28, 2020

    Availability

    Academic Institutions and Nonprofits only

13. Splicing-targeting CRISPR-Cas9 library for human lncRNAs

    Pooled Library

    #119977

    Purpose

    The CRISPR sgRNA library was designed to target the 5' or 3' splice sites of lncRNAs in genome-scale, in order to knockout the targeted lncRNAs.

    Depositor

    Wensheng Wei

    Article

    Liu et al Nat Biotechnol. 2018 Nov 5. pii: nbt.428

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    March 27, 2019

    Availability

    Academic Institutions and Nonprofits only

14. Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set A

    Pooled Library

    #92385

    Purpose

    Crispri

    Depositor

    David Root, John Doench

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Has Service

    Lentiviral Prep

    Use

    Lentiviral

    Available since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

15. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set A

    Pooled Library

    #92379

    Purpose

    CRISPRa

    Depositor

    David Root, John Doench

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Has Service

    Lentiviral Prep

    Use

    Lentiviral

    Available since

    Aug. 3, 2017

    Availability

    Academic Institutions and Nonprofits only

16. Mouse Toronto KnockOut (mTKO) CRISPR Library - pLCKO2

    Pooled Library

    #159393

    Purpose

    Mouse lentiviral genome-wide CRISPR library

    Depositor

    Jason Moffat

    Article

    Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available since

    Nov. 9, 2020

    Availability

    Academic Institutions and Nonprofits only

17. BLaER1 pgRNA CRISPR library

    Pooled Library

    #183825

    Purpose

    CRISPR-Cas9 library to target lncRNAs and protein coding genes with a potential role in B-cell to macrophage transdifferentiation.

    Depositor

    Roderic Guigo

    Article

    Arnan et al BMC Genomics. 2022 May 26;23(1):402. doi

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Aug. 25, 2022

    Availability

    Academic Institutions and Nonprofits only

18. PBbtCRISPRko.v1

    Pooled Library

    #213928

    Purpose

    Uses the PiggyBac transposon system to deliver the library into hard to transduce cells

    Depositor

    Wenfang Spring Tan

    Article

    Tan et al PLoS Pathog. 2023 Dec 6;19(12):e1011822.

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    April 9, 2024

    Availability

    Academic Institutions and Nonprofits only

19. hCRISPRi_dual_1_2

    Pooled Library

    #187246

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

20. hCRISPRi_dual_5_6

    Pooled Library

    #187248

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only