We narrowed to 101 results for: tra

1. Human Metabolic Gene CRISPRa sgRNA library

   Pooled Library

   #187080

   Purpose

   Lentiviral CRISPRa library targeting human metabolic genes for activation of gene expression

   Depositor

   Kivanc Birsoy

   Article

   Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   Lentiviral

   Available Since

   Oct. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

2. Mouse Metabolic Gene CRISPRa sgRNA library

   Pooled Library

   #187081

   Purpose

   Lentiviral CRISPRa library targeting mouse metabolic genes for activation of gene expression

   Depositor

   Kivanc Birsoy

   Article

   Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   Lentiviral

   Available Since

   Oct. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

3. DNA repair library with 1,573 sgRNAs

   Pooled Library

   #177663

   Purpose

   CRISPR-interference (CRISPRi) library of 1,573 sgRNAs targeting 476 genes encoding factors involved in DNA repair and associated processes

   Depositor

   Brittany Adamson

   Article

   Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

   Species

   Homo sapiens

   Use

   CRISPR

   Available Since

   July 11, 2023

   Availability

   Academic Institutions and Nonprofits only

4. KSHV Tiling Library

   Pooled Library

   #180272

   Purpose

   sgRNA library tiling entire ~154 kb of the BAC16 Kaposi’s Sarcoma-associated Herpes viral genome. A guide every ~8 bp allows pooled screening of viral genome.

   Depositor

   Britt Glaunsinger

   Article

   Morgens et al PLoS Pathog. 2022 Jan 18;18(1):e1010236.

   Expression

   Mammalian

   Species

   Kaposi’s sarcoma-associated herpes virus

   Use

   Lentiviral

   Available Since

   Feb. 11, 2022

   Availability

   Academic Institutions and Nonprofits only

5. DNA repair library with 336 sgRNAs

   Pooled Library

   #177664

   Purpose

   CRISPR-interference (CRISPRi) library of 366 sgRNAs targeting 118 genes encoding factors involved in DNA repair and associated processes

   Depositor

   Brittany Adamson

   Article

   Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

   Species

   Homo sapiens

   Use

   CRISPR

   Available Since

   Nov. 29, 2023

   Availability

   Academic Institutions and Nonprofits only

6. SPLINTR GFP v1

   Pooled Library

   #179774

   Purpose

   SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

   Depositor

   Mark Dawson

   Article

   Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

   Expression

   Mammalian

   Use

   Lentiviral

   Available Since

   May 11, 2022

   Availability

   Academic Institutions and Nonprofits only

7. SPLINTR mCHERRY v1

   Pooled Library

   #179775

   Purpose

   SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

   Depositor

   Mark Dawson

   Article

   Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

   Expression

   Mammalian

   Use

   Lentiviral

   Available Since

   May 11, 2022

   Availability

   Academic Institutions and Nonprofits only

8. SPLINTR BFP v1

   Pooled Library

   #179776

   Purpose

   SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

   Depositor

   Mark Dawson

   Article

   Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

   Expression

   Mammalian

   Use

   Lentiviral

   Available Since

   May 11, 2022

   Availability

   Academic Institutions and Nonprofits only

9. Human SLC SAM Library

   Pooled Library

   #132561

   Purpose

   Expresses gRNAs for activation of human Solute Carrier family genes

   Depositor

   Giulio Superti-Furga

   Article

   Rebsamen et al Life Sci Alliance. 2022 Sep 16;5(11):e20

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   May 18, 2020

   Availability

   Academic Institutions and Nonprofits only

10. Human CRISPR Poison Exon Knockout Library

    Pooled Library

    #138084

    Purpose

    The human pgPoison library induces skipping of “poison” cassette exons and corresponding upstream constitutive exons by targeting 3' splice sites with paired gRNAs (pgRNAs).

    Depositor

    Robert Bradley

    Article

    Thomas et al Nat Genet. 2020 Jan;52(1):84-94. doi: 10

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    March 6, 2020

    Availability

    Academic Institutions and Nonprofits only

11. pLCKO2::TKOv3

    Pooled Library

    #125517

    Purpose

    Human CRISPR lentiviral library containing 70,948 guides (4-5 guides/gene) targeting 18,053 human protein-coding genes, in a non-Cas9 containing backbone

    Depositor

    Jason Moffat

    Article

    Mair et al Cell Rep. 2019 Apr 9;27(2):599-615.e12.

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 1, 2019

    Availability

    Academic Institutions and Nonprofits only

12. Human CRISPR lncRNA activation library (SAM) in lenti sgRNA(MS2)_zeo backbone

    Pooled Library

    #1000000106

    Purpose

    Human CRISPR Synergistic Activation Mediator (SAM) pooled library for the transcriptional activation of lncRNAs

    Depositor

    Feng Zhang

    Available Since

    June 5, 2017

    Availability

    Academic Institutions and Nonprofits only

13. pSMAL-CellTag-V1

    Pooled Library

    #115643

    Purpose

    Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

    Depositor

    Samantha Morris

    Article

    Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

    Has Service

    Concentrated Lentiviral Prep

    Expression

    Mammalian

    Species

    Synthetic

    Use

    Lentiviral

    Available Since

    Dec. 5, 2018

    Availability

    Academic Institutions and Nonprofits only

14. pSMAL-CellTag-V2

    Pooled Library

    #115644

    Purpose

    Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

    Depositor

    Samantha Morris

    Article

    Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

    Has Service

    Concentrated Lentiviral Prep

    Expression

    Mammalian

    Species

    Synthetic

    Use

    Lentiviral

    Available Since

    Dec. 5, 2018

    Availability

    Academic Institutions and Nonprofits only

15. pSMAL-CellTag-V3

    Pooled Library

    #115645

    Purpose

    Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

    Depositor

    Samantha Morris

    Article

    Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

    Has Service

    Concentrated Lentiviral Prep

    Expression

    Mammalian

    Species

    Synthetic

    Use

    Lentiviral

    Available Since

    Dec. 5, 2018

    Availability

    Academic Institutions and Nonprofits only

16. LV2btCRISPRko.v1

    Pooled Library

    #213927

    Purpose

    Uses lentivirus to deliver the library into hard-to-transduce cells

    Depositor

    Wenfang Spring Tan

    Article

    Tan et al PLoS Pathog. 2023 Dec 6;19(12):e1011822.

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    April 9, 2024

    Availability

    Academic Institutions and Nonprofits only

17. Lenti-human-TF-gRNA-puromycin

    Pooled Library

    #162275

    Purpose

    This is a gRNA library targeting on ~1600 human transcription factors for genetic screening.

    Depositor

    Chunliang Li

    Article

    Zhang et al Elife. 2020 Oct 1;9. pii: 57858. doi: 10

    Species

    Homo sapiens

    Use

    Lentiviral

    Available Since

    Dec. 15, 2020

    Availability

    Academic Institutions and Nonprofits only

18. Pdest-EF1α-EGFP-32bp barcode polyA library

    Pooled Library

    #211610

    Purpose

    Barcoded retrovirus plasmid library for capturing the transcriptome and viral barcode sequences of individual cells to infer their identities and lineage information.

    Depositor

    Yuejun Chen

    Article

    You et al Cell Stem Cell. 2023 Apr 6;30(4):473-487

    Species

    Synthetic

    Use

    Retroviral

    Available Since

    Aug. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

19. pCMV-Rep78/68 Scanning Saturation Mutagenesis (SSM)

    Pooled Library

    #198050

    Purpose

    By supplying an AAV cap gene of interest in trans, researchers can use this library to investigate the effects of rep mutations on production of a wide range of AAV capsid serotypes

    Depositor

    George Church

    Article

    Jain et al Elife. 2024 Mar 27;12:RP87730. doi: 10.7

    Expression

    Mammalian

    Use

    AAV

    Available Since

    May 4, 2023

    Availability

    Academic Institutions and Nonprofits only

20. Watermelon

    Pooled Library

    #155257

    Purpose

    Lineage tracing library

    Depositor

    Joan Brugge, Aviv Regev

    Article

    Oren et al Nature. 2021 Aug 11. pii: 10.1038/s41586

    Expression

    Mammalian

    Use

    Lentiviral

    Available Since

    Oct. 15, 2021

    Availability

    Academic Institutions and Nonprofits only