We narrowed to 118 results for: {{{s}}}

1. MinLibCas9

   Pooled Library

   #164896

   Purpose

   Human genome-wide CRISPR-Cas9 gRNA library, optimised by mining existing large-scale screening datasets, which provides a >60% reduction in size while preserving key information content

   Depositor

   Mathew Garnett

   Article

   Gonçalves et al Genome Biol. 2021 Jan 21;22(1):40. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   May 20, 2021

   Availability

   Academic Institutions and Nonprofits only

2. SPLINTR mCHERRY v1

   Pooled Library

   #179775

   Purpose

   SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

   Depositor

   Mark Dawson

   Article

   Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   May 11, 2022

   Availability

   Academic Institutions and Nonprofits only

3. SPLINTR BFP v1

   Pooled Library

   #179776

   Purpose

   SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

   Depositor

   Mark Dawson

   Article

   Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   May 11, 2022

   Availability

   Academic Institutions and Nonprofits only

4. pCVSN2c-MCP-oScarlet-KASH-6xMS2 Barcode Library

   Pooled Library

   #227672

   Purpose

   RVdG genome plasmids that carry an error-correctable barcode compatible with 3’ capture single cell or single nuclei RNA sequencing readout. For the production of CVS N2c strain G-deleted rabies virus

   Depositor

   Cathryn Cadwell, Tomasz Nowakowski

   Article

   Shin et al bioRxiv [Preprint]. 2024 Dec 11:2024.10.

   Expression

   Mammalian

   Species

   Synthetic

   Available since

   Feb. 12, 2025

   Availability

   Academic Institutions and Nonprofits only

5. Bison sgRNA library

   Pooled Library

   #169942

   Purpose

   The BISON CRISPR library targets 713 E1, E2, and E3 ubiquitin ligases, deubiquitinases, and control genes and contains 2,852 guide RNAs. It was cloned into the pXPR003.

   Depositor

   Benjamin Ebert

   Article

   Slabicki et al Nature. 2020 Sep;585(7824):293-297. doi:

   Use

   Lentiviral

   Available since

   Sept. 9, 2021

   Availability

   Academic Institutions and Nonprofits only

6. Human Base Editing Sensor Library

   Pooled Library

   #179218

   Purpose

   sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

   Depositor

   Lukas Dow

   Article

   Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   June 16, 2022

   Availability

   Academic Institutions and Nonprofits only

7. Wei lab paired-guide RNA (pgRNA) CRISPR–Cas9 library for human long non-coding RNAs (lncRNAs)

   Pooled Library

   #89640

   Purpose

   Paired sgRNA library containing 12,472 pgRNAs targeting 671 human long non-coding RNAs (lncRNAs)

   Depositor

   Wensheng Wei

   Article

   Zhu et al Nat Biotechnol. 2016 Dec;34(12):1279-128

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   May 17, 2017

   Availability

   Academic Institutions and Nonprofits only

8. Mouse Base Editing Sensor Library

   Pooled Library

   #179217

   Purpose

   sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

   Depositor

   Lukas Dow

   Article

   Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   June 16, 2022

   Availability

   Academic Institutions and Nonprofits only

9. ALL-PAM sensor Library

   Pooled Library

   #179219

   Purpose

   10 human and mouse sgRNAs each where for each sgRNA the tethered target site has 1 of 64 possible 3 bp PAM sequences.

   Depositor

   Lukas Dow

   Article

   Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   June 16, 2022

   Availability

   Academic Institutions and Nonprofits only

10. TP53 MITE Library

    Pooled Library

    #113569

    Purpose

    Pooled lentiviral plasmid library containing ~8,000 single amino acid substitution and nonsense mutant variants of p53

    Depositor

    William Hahn, David Root

    Article

    Giacomelli et al Nat Genet. 2018 Oct;50(10):1381-1387. do

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Jan. 4, 2019

    Availability

    Academic Institutions and Nonprofits only

11. CROPseq-iT7 Human CRISPR Knockout Pooled Library (Brunello)

    Pooled Library

    #223064

    Purpose

    Optical pooled genome-scale CRISPR KO screening using Nuclear In-Situ Sequencing (NIS-Seq)

    Depositor

    Jonathan Schmid-Burgk

    Article

    Fandrey et al Nat Biotechnol. 2024 Dec 19. doi: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    May 23, 2025

    Availability

    Academic Institutions and Nonprofits only

12. HR700_TP53Exon5mut

    Pooled Library

    #229137

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 5 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

13. HR700_TP53Exon6mut

    Pooled Library

    #229138

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 6 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

14. HR700_TP53Exon7mut

    Pooled Library

    #229139

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 7 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

15. HR700_TP53Exon8mut

    Pooled Library

    #229140

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 8 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

16. Sctrans-PP

    Pooled Library

    #153101

    Purpose

    CRISPR library targets all non-essential and conditionally essential transporter genes in S. cerevisiae

    Depositor

    Irina Borodina

    Article

    Wang et al Metab Eng. 2021 Jan 16. pii: S1096-7176(

    Expression

    Yeast

    Species

    Saccharomyces cerevisiae

    Use

    CRISPR

    Available since

    Jan. 20, 2021

    Availability

    Academic Institutions and Nonprofits only

17. Sctrans-PP-Grp1

    Pooled Library

    #153102

    Purpose

    CRISPR library targets a sub-pool of transporter genes in S. cerevisiae

    Depositor

    Irina Borodina

    Article

    Wang et al Metab Eng. 2021 Jan 16. pii: S1096-7176(

    Expression

    Yeast

    Species

    Saccharomyces cerevisiae

    Use

    CRISPR

    Available since

    Jan. 20, 2021

    Availability

    Academic Institutions and Nonprofits only

18. Sctrans-PP-Grp2

    Pooled Library

    #153103

    Purpose

    CRISPR library targets a sub-pool of transporter genes in S. cerevisiae

    Depositor

    Irina Borodina

    Article

    Wang et al Metab Eng. 2021 Jan 16. pii: S1096-7176(

    Expression

    Yeast

    Species

    Saccharomyces cerevisiae

    Use

    CRISPR

    Available since

    Jan. 20, 2021

    Availability

    Academic Institutions and Nonprofits only

19. Sctrans-PP-Grp3

    Pooled Library

    #153104

    Purpose

    CRISPR library targets a sub-pool of transporter genes in S. cerevisiae

    Depositor

    Irina Borodina

    Article

    Wang et al Metab Eng. 2021 Jan 16. pii: S1096-7176(

    Expression

    Yeast

    Species

    Saccharomyces cerevisiae

    Use

    CRISPR

    Available since

    Jan. 20, 2021

    Availability

    Academic Institutions and Nonprofits only

20. Sctrans-PP-Grp4

    Pooled Library

    #153105

    Purpose

    CRISPR library targets a sub-pool of transporter genes in S. cerevisiae

    Depositor

    Irina Borodina

    Article

    Wang et al Metab Eng. 2021 Jan 16. pii: S1096-7176(

    Expression

    Yeast

    Species

    Saccharomyces cerevisiae

    Use

    CRISPR

    Available since

    Jan. 20, 2021

    Availability

    Academic Institutions and Nonprofits only