We narrowed to 165 results for: ell

1. Mouse Metabolism Library

   Pooled Library

   #163966

   Purpose

   Lentiviral CRISPR library targets 2,918 mouse metabolic genes with ~18,000 guide RNAs. The library contains ~6 gRNAs per gene.

   Depositor

   Alec Kimmelman

   Article

   Biancur et al Cell Metab. 2020 Oct 28. pii: S1550-4131

   Use

   CRISPR and Lentiviral

   Available since

   July 1, 2021

   Availability

   Academic Institutions and Nonprofits only

2. Human Lentiviral sgRNA Library - Kinases

   Pooled Library

   #51044

   Purpose

   Sub-pool of Sabatini/Lander sgRNA library enriched for kinase targets.

   Depositor

   Eric Lander, David Sabatini

   Article

   Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 7, 2014

   Availability

   Academic Institutions and Nonprofits only

3. Human Lentiviral sgRNA Library - Nuclear

   Pooled Library

   #51047

   Purpose

   Sub-pool of Sabatini/Lander sgRNA library enriched for nuclear targets.

   Depositor

   Eric Lander, David Sabatini

   Article

   Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 7, 2014

   Availability

   Academic Institutions and Nonprofits only

4. Humagne Set C

   Pooled Library

   #172650

   Purpose

   Set C contains best-ranked guides 1 and 4.

   Depositor

   John Doench, David Root

   Article

   DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

   Expression

   Mammalian

   Available since

   Nov. 10, 2021

   Availability

   Academic Institutions and Nonprofits only

5. Humagne Set D

   Pooled Library

   #172651

   Purpose

   Set D contains best-ranked guides 2 and 3.

   Depositor

   John Doench, David Root

   Article

   DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

   Expression

   Mammalian

   Available since

   Nov. 10, 2021

   Availability

   Academic Institutions and Nonprofits only

6. Human Lentiviral sgRNA Library - Control

   Pooled Library

   #51048

   Purpose

   Sub-pool of Sabatini/Lander sgRNA library enriched for control targets.

   Depositor

   Eric Lander, David Sabatini

   Article

   Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 7, 2014

   Availability

   Academic Institutions and Nonprofits only

7. sgRNA pool for Streptococcus pneumoniae

   Pooled Library

   #170432

   Purpose

   CRISPR library targeting S. pneumoniae D39V

   Depositor

   Jan-Willem Veening

   Article

   Liu et al Cell Host Microbe. 2021 Jan 13;29(1):107

   Expression

   Bacterial

   Use

   CRISPR

   Available since

   Aug. 31, 2021

   Availability

   Academic Institutions and Nonprofits only

8. Human Lentiviral sgRNA Library - Ribosomal Proteins

   Pooled Library

   #51045

   Purpose

   Sub-pool of Sabatini/Lander sgRNA library enriched for ribosomal gene targets.

   Depositor

   Eric Lander, David Sabatini

   Article

   Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 7, 2014

   Availability

   Academic Institutions and Nonprofits only

9. Human Lentiviral sgRNA Library - Unknown Function

   Pooled Library

   #51043

   Purpose

   Sub-pool of Sabatini/Lander sgRNA library enriched for gene targets of unknown function.

   Depositor

   Eric Lander, David Sabatini

   Article

   Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 7, 2014

   Availability

   Academic Institutions and Nonprofits only

10. Human Kinase Domain-Focused CRISPR Knockout Library

    Pooled Library

    #117725

    Purpose

    gRNAs targeting the kinase domain of human protein kinases

    Depositor

    Christopher Vakoc

    Article

    Tarumoto et al Mol Cell. 2018 Feb 28. pii: S1097-2765(1

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Jan. 4, 2019

    Availability

    Academic Institutions and Nonprofits only

11. Human Genome-Wide Reduced Double-gRNA library

    Pooled Library

    #137999

    Purpose

    This gRNA library targets the human coding genome, aimed to reduce the scale of genome-wide perturbation screens up to fivefold compared to conventional methods, without sacrificing performance.

    Depositor

    Leopold Parts

    Article

    Peets et al bioRxiv 859652

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Oct. 15, 2020

    Availability

    Academic Institutions and Nonprofits only

12. Human Transporter Knockout library

    Pooled Library

    #213695

    Purpose

    Next generation transporter-focused CRISPR/Cas9 library targeting transmembrane transporters to test the impact of transporters on biological processes.

    Depositor

    Giulio Superti-Furga, RESOLUTE Consortium

    Article

    Ferdigg et al Life Sci Alliance. 2024 Nov 22;8(2):e202

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Sept. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

13. Human Paralog Knockout Library (pgPEN)

    Pooled Library

    #171172

    Purpose

    CRISPR library targets human duplicate paralog gene pairs

    Depositor

    Alice Berger

    Article

    Parrish et al Cell Rep. 2021 Aug 31;36(9):109597. doi:

    Expression

    Mammalian

    Species

    Homo sapiens and Synthetic

    Use

    CRISPR and Lentiviral

    Available since

    Sept. 28, 2021

    Availability

    Academic Institutions and Nonprofits only

14. Watermelon

    Pooled Library

    #155257

    Purpose

    Lineage tracing library

    Depositor

    Joan Brugge, Aviv Regev

    Article

    Oren et al Nature. 2021 Aug 11. pii: 10.1038/s41586

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    Oct. 15, 2021

    Availability

    Academic Institutions and Nonprofits only

15. hCRISPRi_dual_1_2

    Pooled Library

    #187246

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Jonathan Weissman, Marco Jost

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

16. Mouse messenger-RBP sgRNA library

    Pooled Library

    #169082

    Purpose

    CRISPR library targeting mouse genes

    Depositor

    Martin Turner

    Article

    Turner et al eLife. 2022 Apr 22;11. pii: 72313. doi:

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available since

    Sept. 10, 2021

    Availability

    Academic Institutions and Nonprofits only

17. hCRISPRa_dual_1_2

    Pooled Library

    #187249

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Jonathan Weissman, Marco Jost

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

18. hCRISPRi_dual_5_6

    Pooled Library

    #187248

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Jonathan Weissman, Marco Jost

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

19. hCRISPRi_dual_3_4

    Pooled Library

    #187247

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Jonathan Weissman, Marco Jost

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

20. mTORC1 Focused library

    Pooled Library

    #164084

    Purpose

    Lentiviral CRISPR library targets human mTORC1 signaling pathway

    Depositor

    David Sabatini

    Article

    Condon et al Proc Natl Acad Sci U S A. 2021 Jan 26;11

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Jan. 11, 2021

    Availability

    Academic Institutions and Nonprofits only