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We narrowed to 285 results for: crispr

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Showing: 141 - 160 of 285 results

  1. Mouse Validation (mVAL) CRISPR Library

    Pooled library
    #159391
    Purpose
    Targets 182 immune evasion genes. Designed for loss-of-function screening against genes shown to increase sensistivity or resistance of cancer cells to cytotoxic T lymphocyte-mediated toxicity.
    Depositor
    Jason Moffat
    Publication
    Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:
    Expression
    Mammalian
    Species
    Mus musculus
    Use
    CRISPR and Lentiviral
    Available since
    Nov. 9, 2020
    Availability
    Academic Institutions and Nonprofits only

  4. Oxford Drosophila melanogaster Genome-wide CRISPR Library

    Pooled library
    #64750
    Purpose
    Library designed for genomic targeting and screening in Drosophila cells. All possible gRNA target sites within the shared exonic regions on either DNA strand of the Drosophila genome were computed.
    Depositor
    Ji-Long Liu
    Publication
    Bassett et al J Genet Genomics. 2015 Jun 20;42(6):301-
    Expression
    Insect
    Species
    Drosophila melanogaster, Streptococcus pyogenes, and Synthetic
    Use
    CRISPR
    Available since
    March 7, 2016
    Availability
    Academic Institutions and Nonprofits only

  15. Human CRISPR Poison Exon Knockout Library

    Pooled library
    #138084
    Purpose
    Targets 3' splice sites with paired gRNAs. Induces skipping of poison cassette exons and matching upstream constitutive exons. Compare loss of a constitutive coding exon with loss of a poison exon.
    Depositor
    Robert Bradley
    Publication
    Thomas et al Nat Genet. 2020 Jan;52(1):84-94. doi: 10
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    March 6, 2020
    Availability
    Academic Institutions and Nonprofits only
    Cited by
    1 Article

  16. Human Brunello kinome pooled library, guides 5-8 in lentiCRISPRv2 backbone

    Pooled library
    #75315
    Purpose
    Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls
    Depositor
    John Doench, David Root
    Publication
    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103
    Expression
    Mammalian
    Use
    CRISPR and Lentiviral
    Available since
    June 27, 2016
    Availability
    Academic Institutions and Nonprofits only
    Cited by
    3 Articles
Showing: 141 - 160 of 285 results