966 results

1. pAAV-hSynapsin1-axon-GCaMP6f (AAV1)

   Viral Prep

   #112000-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-hSynapsin1-axon-GCaMP6f (#112000). In addition to the viral particles, you will also receive purified pAAV-hSynapsin1-axon-GCaMP6f plasmid DNA. Synapsin-driven, axon-targeted GCaMP6f calcium sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Lin Tian

   Article

   Broussard et al Nat Neurosci. 2018 Sep;21(9):1272-1280.

   Promoter

   Syn

   Tags

   None

   Available since

   March 12, 2021

   Availability

   Academic Institutions and Nonprofits only

2. pAAV-CAG-2xNLS-tdTomato-WPRE-hGHpolyA (AAV9)

   Viral Prep

   #192552-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-CAG-2xNLS-tdTomato-WPRE-hGHpolyA (#192552). In addition to the viral particles, you will also receive purified pAAV-CAG-2xNLS-tdTomato-WPRE-hGHpolyA plasmid DNA. CAG-driven expression of nuclear localized tdTomato. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Guoping Feng

   Promoter

   CAG

   Tags

   tdTomato

   Available since

   June 26, 2024

   Availability

   Academic Institutions and Nonprofits only

3. pAAV-EF1a-Flpo (AAV2)

   Viral Prep

   #55637-AAV2

   Purpose

   Ready-to-use AAV2 particles produced from pAAV-EF1a-Flpo (#55637). In addition to the viral particles, you will also receive purified pAAV-EF1a-Flpo plasmid DNA. EF1a-driven Flpo recombinase expression. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Article

   Fenno et al Nat Methods. 2014 Jul;11(7):763-72. doi:

   Promoter

   EF1a

   Tags

   None

   Available since

   March 18, 2024

   Availability

   Academic Institutions and Nonprofits only

4. pAAV.CAG.GCaMP6f.WPRE.SV40 (AAV1)

   Viral Prep

   #100836-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV.CAG.GCaMP6f.WPRE.SV40 (#100836). In addition to the viral particles, you will also receive purified pAAV.CAG.GCaMP6f.WPRE.SV40 plasmid DNA. CAG-driven GCaMP6f calcium sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   GENIE Project, Douglas Kim

   Article

   Chen et al Nature. 2013 Jul 18;499(7458):295-300. d

   Promoter

   CAG

   Tags

   None

   Available since

   March 16, 2018

   Availability

   Academic Institutions and Nonprofits only

5. pAAV-mDlx-GFP-Fishell-1 (AAV9)

   Viral Prep

   #83900-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-mDlx-GFP-Fishell-1 (#83900). In addition to the viral particles, you will also receive purified pAAV-mDlx-GFP-Fishell-1 plasmid DNA. mDlx-driven expression of GFP in GABA-ergic interneurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Gordon Fishell

   Article

   Dimidschstein et al Nat Neurosci. 2016 Oct 31. doi: 10.1038/

   Promoter

   mDlx

   Tags

   GFP

   Available since

   Nov. 13, 2020

   Availability

   Academic Institutions and Nonprofits only

6. AAV CAMKII PSAM4 GlyR IRES EGFP (AAV5)

   Viral Prep

   #119744-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from AAV CAMKII PSAM4 GlyR IRES EGFP (#119744). In addition to the viral particles, you will also receive purified AAV CAMKII PSAM4 GlyR IRES EGFP plasmid DNA. CamKII-driven expression of PSAM4 GlyR IRES EGFP for neuronal silencing. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Scott Sternson

   Article

   Magnus et al Science. 2019 Mar 14. pii: science.aav52

   Promoter

   CaMKII

   Tags

   EGFP

   Available since

   Aug. 28, 2020

   Availability

   Academic Institutions and Nonprofits only

7. pAAV-CAG-GFP (AAV2 trial size)

   Viral Prep

   #37825-AAV2.T

   Purpose

   Ready-to-use AAV2 trial size particles produced from pAAV-CAG-GFP (#37825). In addition to the viral particles, you will also receive purified pAAV-CAG-GFP plasmid DNA. CAG-driven GFP expression. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Edward Boyden

   Promoter

   CAG

   Tags

   GFP

   Available since

   May 29, 2019

   Availability

   Academic Institutions and Nonprofits only

8. pAAV-hsyn-GRAB_DA-mut (AAV9)

   Viral Prep

   #140555-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-hsyn-GRAB_DA-mut (#140555). In addition to the viral particles, you will also receive purified pAAV-hsyn-GRAB_DA-mut plasmid DNA. Synapsin-driven expression of control dopamine sensor GRAB_DA-mut (does not respond to DA). These AAV preparations are suitable purity for injection into animals.

   Depositor

   Yulong Li

   Article

   Sun et al Nat Methods. 2020 Nov;17(11):1156-1166.

   Promoter

   Syn

   Tags

   None

   Available since

   Aug. 31, 2021

   Availability

   Academic Institutions and Nonprofits only

9. pAAV-Ef1a-fDIO EYFP (AAV8)

   Viral Prep

   #55641-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-Ef1a-fDIO EYFP (#55641). In addition to the viral particles, you will also receive purified pAAV-Ef1a-fDIO EYFP plasmid DNA. EF1a-driven, Flp-dependent expression of EYFP. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Article

   Fenno et al Nat Methods. 2014 Jul;11(7):763-72. doi:

   Promoter

   EF1a

   Tags

   None

   Available since

   Dec. 18, 2024

   Availability

   Academic Institutions and Nonprofits only

10. pAAV-S5E2-GCaMP6f (AAV1)

    Viral Prep

    #135632-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-S5E2-GCaMP6f (#135632). In addition to the viral particles, you will also receive purified pAAV-S5E2-GCaMP6f plasmid DNA. Expression of GCaMP6f under the control of the E2 regulatory element. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jordane Dimidschstein

    Article

    Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

    Promoter

    Tags

    None

    Available since

    Nov. 11, 2020

    Availability

    Academic Institutions and Nonprofits only

11. pAAV-hsyn-flex-Voltron-ST (AAV1)

    Viral Prep

    #119036-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-hsyn-flex-Voltron-ST (#119036). In addition to the viral particles, you will also receive purified pAAV-hsyn-flex-Voltron-ST plasmid DNA. Synapsin-driven, cre-dependent expression of genetically encoded fluorescent voltage indicator Voltron1 with a soma-targeting sequence. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Eric Schreiter

    Article

    Abdelfattah et al Science. 2019 Aug 1. pii: science.aav641

    Promoter

    Syn

    Tags

    None

    Available since

    April 10, 2019

    Availability

    Academic Institutions and Nonprofits only

12. pAAV-Syn-Chronos-GFP (AAV Retrograde)

    Viral Prep

    #59170-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-Syn-Chronos-GFP (#59170). In addition to the viral particles, you will also receive purified pAAV-Syn-Chronos-GFP plasmid DNA. Chronos-GFP under the control of the Synapsin promoter. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Edward Boyden

    Article

    Klapoetke et al Nat Methods. 2014 Mar;11(3):338-46. doi:

    Promoter

    Syn

    Tags

    GFP

    Available since

    Oct. 3, 2017

    Availability

    Academic Institutions and Nonprofits only

13. pAAV_hSyn-DIO-PdCO-mScarlet-WPRE (AAV5)

    Viral Prep

    #198511-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV_hSyn-DIO-PdCO-mScarlet-WPRE (#198511). In addition to the viral particles, you will also receive purified pAAV_hSyn-DIO-PdCO-mScarlet-WPRE plasmid DNA. Syn-driven Cre-dependent expression of optimized PdCO in frame with mScarlet. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Ofer Yizhar

    Article

    Wietek et al Nat Methods. 2024 May 29. doi: 10.1038/s

    Promoter

    Syn

    Tags

    mScarlet (Cre-dependent)

    Available since

    Sept. 27, 2024

    Availability

    Academic Institutions and Nonprofits only

14. pAAV_hSyn-PdCO-EGFP-WPRE (AAV1)

    Viral Prep

    #198513-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV_hSyn-PdCO-EGFP-WPRE (#198513). In addition to the viral particles, you will also receive purified pAAV_hSyn-PdCO-EGFP-WPRE plasmid DNA. Synapsin-driven expression of the optimized opsin PdCO in frame with EGFP. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Ofer Yizhar

    Article

    Wietek et al Nat Methods. 2024 May 29. doi: 10.1038/s

    Promoter

    Syn

    Tags

    EGFP

    Available since

    April 10, 2024

    Availability

    Academic Institutions and Nonprofits only

15. AAV-CAG-jGCaMP8s-WPRE (AAV1)

    Viral Prep

    #179256-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from AAV-CAG-jGCaMP8s-WPRE (#179256). In addition to the viral particles, you will also receive purified AAV-CAG-jGCaMP8s-WPRE plasmid DNA. CAG-driven expression of calcium sensor GCaMP8s. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    CAG

    Tags

    None

    Available since

    Jan. 24, 2024

    Availability

    Academic Institutions and Nonprofits only

16. pAAV-nEF-Coff/Fon-ChRmine-oScarlet (AAV8)

    Viral Prep

    #137160-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-nEF-Coff/Fon-ChRmine-oScarlet (#137160). In addition to the viral particles, you will also receive purified pAAV-nEF-Coff/Fon-ChRmine-oScarlet plasmid DNA. nEF-driven expression of ChRmine-oScarlet in the presence of Flp (inhibited in the presence of Cre). These AAV preparations are suitable purity for injection into animals.

    Depositor

    INTRSECT 2.0 Project, Karl Deisseroth

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    nEF

    Tags

    oScarlet (Flp-dependent)

    Available since

    Oct. 14, 2020

    Availability

    Academic Institutions and Nonprofits only

17. pAAV-Ef1a-mCherry (AAV Retrograde)

    Viral Prep

    #114470-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-Ef1a-mCherry (#114470). In addition to the viral particles, you will also receive purified pAAV-Ef1a-mCherry plasmid DNA. EF1a-driven mCherry expression. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Promoter

    EF1a

    Tags

    mCherry

    Available since

    Sept. 15, 2021

    Availability

    Academic Institutions and Nonprofits only

18. pAAV.hSyn.FLEX.iGluSnFR3.v857.PDGFR.codonopt (AAV1)

    Viral Prep

    #175180-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV.hSyn.FLEX.iGluSnFR3.v857.PDGFR.codonopt (#175180). In addition to the viral particles, you will also receive purified pAAV.hSyn.FLEX.iGluSnFR3.v857.PDGFR.codonopt plasmid DNA. Synapsin-driven, Cre-dependent, iGluSnFR3 glutamate sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Kaspar Podgorski

    Article

    Aggarwal et al Nat Methods. 2023 May 4. doi: 10.1038/s4

    Promoter

    Syn

    Tags

    None

    Available since

    July 1, 2022

    Availability

    Academic Institutions and Nonprofits only

19. pGP-AAV-syn-FLEX-jGCaMP7b-WPRE (AAV1)

    Viral Prep

    #104493-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pGP-AAV-syn-FLEX-jGCaMP7b-WPRE (#104493). In addition to the viral particles, you will also receive purified pGP-AAV-syn-FLEX-jGCaMP7b-WPRE plasmid DNA. Synapsin-driven, Cre-dependent jGCaMP7b expression. jGCaMP7b exhibits the brightest resting fluorescence and can be used for imaging of small neuronal processes (dendrites and axons). These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project, Douglas Kim

    Article

    Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

    Promoter

    Syn

    Tags

    None

    Available since

    Jan. 3, 2019

    Availability

    Academic Institutions and Nonprofits only

20. rAAV-CAG::FLEX-rev:: hM4D-2a-GFP (AAV1)

    Viral Prep

    #52536-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from rAAV-CAG::FLEX-rev:: hM4D-2a-GFP (#52536). In addition to the viral particles, you will also receive purified rAAV-CAG::FLEX-rev:: hM4D-2a-GFP plasmid DNA. CAG driven, Cre-dependent expression of hM4D and GFP. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Scott Sternson

    Article

    Atasoy et al Nature. 2012 Aug 9;488(7410):172-7. doi:

    Promoter

    CAG

    Tags

    GFP

    Available since

    Dec. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

21. pAAV-Ef1a-Coff/Fon-GCaMP6F (AAV8)

    Viral Prep

    #137124-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-Ef1a-Coff/Fon-GCaMP6F (#137124). In addition to the viral particles, you will also receive purified pAAV-Ef1a-Coff/Fon-GCaMP6F plasmid DNA. EF1a-driven, Flp-dependent expression of GCaMP6f (inhibited in presence of Cre). These AAV preparations are suitable purity for injection into animals.

    Depositor

    INTRSECT 2.0 Project, Karl Deisseroth

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    EF1a

    Tags

    None

    Available since

    May 18, 2021

    Availability

    Academic Institutions and Nonprofits only

22. pAAV-Ef1a-fDIO-ChrimsonR-tdTomato (AAV1)

    Viral Prep

    #171027-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-Ef1a-fDIO-ChrimsonR-tdTomato (#171027). In addition to the viral particles, you will also receive purified pAAV-Ef1a-fDIO-ChrimsonR-tdTomato plasmid DNA. Flp-dependent, Ef1a-driven expression of ChrimsonR-tdTomato fusion for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Patricia Jensen

    Article

    Sciolino et al Sci Adv. 2022 Aug 19;8(33):eabn9134. doi

    Promoter

    EF1a

    Tags

    tdTomato

    Available since

    July 21, 2023

    Availability

    Academic Institutions and Nonprofits only

23. pAAV-S5E6-dTom-nlsdTom (AAV1)

    Viral Prep

    #135641-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-S5E6-dTom-nlsdTom (#135641). In addition to the viral particles, you will also receive purified pAAV-S5E6-dTom-nlsdTom plasmid DNA. Bicistronic expression of dTomato and nuclear-targeted dTomato in VIP cortical interneurons under the control of the E6 regulatory element. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jordane Dimidschstein

    Article

    Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

    Promoter

    Tags

    dTomato

    Available since

    Feb. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

24. pAAV-CaMKIIa-EGFP (AAV2)

    Viral Prep

    #50469-AAV2

    Purpose

    Ready-to-use AAV2 particles produced from pAAV-CaMKIIa-EGFP (#50469). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-EGFP plasmid DNA. CamKIIa-driven EGFP expression control. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Promoter

    CaMKII

    Tags

    EGFP

    Available since

    Jan. 6, 2022

    Availability

    Academic Institutions and Nonprofits only

25. pAAV.CAG.Flex.GCaMP6s.WPRE.SV40 (AAV5)

    Viral Prep

    #100842-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV.CAG.Flex.GCaMP6s.WPRE.SV40 (#100842). In addition to the viral particles, you will also receive purified pAAV.CAG.Flex.GCaMP6s.WPRE.SV40 plasmid DNA. CAG-driven, Cre-dependent GCaMP6s calcium sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project, Douglas Kim

    Article

    Chen et al Nature. 2013 Jul 18;499(7458):295-300. d

    Promoter

    CAG

    Tags

    None

    Available since

    May 11, 2018

    Availability

    Academic Institutions and Nonprofits only

26. pAAV-nEF-Coff/Fon-Arch3.3-p2a-EYFP (AAV8)

    Viral Prep

    #137150-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-nEF-Coff/Fon-Arch3.3-p2a-EYFP (#137150). In addition to the viral particles, you will also receive purified pAAV-nEF-Coff/Fon-Arch3.3-p2a-EYFP plasmid DNA. nEF-driven, Flp-dependent expression of Arch3.3-EYFP (inhibited in presence of Cre) for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    INTRSECT 2.0 Project, Karl Deisseroth

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    nEF

    Tags

    EYFP (Flp-dependent)

    Available since

    May 5, 2021

    Availability

    Academic Institutions and Nonprofits only

27. pAAV.CAG.hChR2(H134R)-mCherry.WPRE.SV40 (AAV5)

    Viral Prep

    #100054-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV.CAG.hChR2(H134R)-mCherry.WPRE.SV40 (#100054). In addition to the viral particles, you will also receive purified pAAV.CAG.hChR2(H134R)-mCherry.WPRE.SV40 plasmid DNA. CAG-driven, humanized channelrhodopsin H134R mutant fused to mCherry for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Promoter

    CAG

    Tags

    mCherry

    Available since

    Feb. 15, 2018

    Availability

    Academic Institutions and Nonprofits only

28. pAAV-hSyn-Cre-P2A-dTomato (AAV2)

    Viral Prep

    #107738-AAV2

    Purpose

    Ready-to-use AAV2 particles produced from pAAV-hSyn-Cre-P2A-dTomato (#107738). In addition to the viral particles, you will also receive purified pAAV-hSyn-Cre-P2A-dTomato plasmid DNA. hSyn-driven expression of Cre and dTomato (physically separate). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Rylan Larsen

    Promoter

    Syn

    Tags

    dTomato (physically separate, not a fusion protein)

    Available since

    Feb. 25, 2021

    Availability

    Academic Institutions and Nonprofits only

29. pAAV-CaMKIIa-mScarlet (AAV8)

    Viral Prep

    #131000-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-CaMKIIa-mScarlet (#131000). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-mScarlet plasmid DNA. CamKIIa-driven expression of mScarlet. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Marshel et al Science. 2019 Aug 9;365(6453). pii: scie

    Promoter

    CaMKII

    Tags

    mScarlet

    Available since

    Sept. 27, 2023

    Availability

    Academic Institutions and Nonprofits only

30. pGP-AAV-syn-jGCaMP7s-WPRE (AAV Retrograde)

    Viral Prep

    #104487-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pGP-AAV-syn-jGCaMP7s-WPRE (#104487). In addition to the viral particles, you will also receive purified pGP-AAV-syn-jGCaMP7s-WPRE plasmid DNA. Synapsin-driven GCaMP7s calcium sensor. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project, Douglas Kim

    Article

    Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

    Promoter

    Syn

    Tags

    None

    Available since

    May 31, 2018

    Availability

    Academic Institutions and Nonprofits only

31. pAAV-Ef1a-sRGECO (AAV8)

    Viral Prep

    #137125-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-Ef1a-sRGECO (#137125). In addition to the viral particles, you will also receive purified pAAV-Ef1a-sRGECO plasmid DNA. EF1a-driven expression of cytosolic sRGECO calcium sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    INTRSECT 2.0 Project, Karl Deisseroth

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    EF1a

    Tags

    None

    Available since

    May 6, 2021

    Availability

    Academic Institutions and Nonprofits only

32. pZac2.1-GfaABC1D-lck-jGCaMP8f (AAV1)

    Viral Prep

    #176759-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pZac2.1-GfaABC1D-lck-jGCaMP8f (#176759). In addition to the viral particles, you will also receive purified pZac2.1-GfaABC1D-lck-jGCaMP8f plasmid DNA. GfaABC1D-driven expression of membrane-bound calcium sensor GCaMP8f. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    GfaABC1D

    Tags

    None

    Available since

    July 12, 2023

    Availability

    Academic Institutions and Nonprofits only

33. pAAV-hSyn-EGFP (AAV8 trial size)

    Viral Prep

    #50465-AAV8.T

    Purpose

    Ready-to-use AAV8 trial size particles produced from pAAV-hSyn-EGFP (#50465). In addition to the viral particles, you will also receive purified pAAV-hSyn-EGFP plasmid DNA. hSyn-driven EGFP expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Promoter

    Syn

    Tags

    EGFP

    Available since

    May 29, 2019

    Availability

    Academic Institutions and Nonprofits only

34. pAAV-CAG-SomaGCaMP6f2 (AAV8)

    Viral Prep

    #158757-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-CAG-SomaGCaMP6f2 (#158757). In addition to the viral particles, you will also receive purified pAAV-CAG-SomaGCaMP6f2 plasmid DNA. CAG-driven expression of soma-targeting GCaMP6f2. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Edward Boyden

    Article

    Shemesh et al Neuron. 2020 Jun 26. pii: S0896-6273(20)

    Promoter

    CAG promoter

    Tags

    None

    Available since

    Feb. 23, 2021

    Availability

    Academic Institutions and Nonprofits only

35. AiP11839-pAAV-hSyn1-SYFP2-10aa-H2B-WPRE3-BGHpA (Alias: CN1839) (AAV PHP.eB)

    Viral Prep

    #163509-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from AiP11839-pAAV-hSyn1-SYFP2-10aa-H2B-WPRE3-BGHpA (Alias: CN1839) (#163509). In addition to the viral particles, you will also receive purified AiP11839-pAAV-hSyn1-SYFP2-10aa-H2B-WPRE3-BGHpA (Alias: CN1839) plasmid DNA. hSyn1-driven expression for nuclear SYFP2 labeling in neurons. Useful for nuclear isolation and scRNA-seq applications. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jonathan Ting, The Allen Institute for Brain Science

    Article

    Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

    Promoter

    Syn

    Tags

    SYFP2

    Available since

    Aug. 17, 2022

    Availability

    Academic Institutions and Nonprofits only

36. pAAV-Ef1a-DIO EYFP (AAV2)

    Viral Prep

    #27056-AAV2

    Purpose

    Ready-to-use AAV2 particles produced from pAAV-Ef1a-DIO EYFP (#27056). In addition to the viral particles, you will also receive purified pAAV-Ef1a-DIO EYFP plasmid DNA. EF1a-driven, cre-dependent EYFP expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Promoter

    Tags

    EYFP (Cre-dependent)

    Available since

    Feb. 15, 2018

    Availability

    Academic Institutions and Nonprofits only

37. pAAV-Ef1a-DIO-PPO-Venus (AAV9)

    Viral Prep

    #139505-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-Ef1a-DIO-PPO-Venus (#139505). In addition to the viral particles, you will also receive purified pAAV-Ef1a-DIO-PPO-Venus plasmid DNA. EF1a-driven, Cre-dependent expression of Venus-tagged parapinopsin for spatiotemporal control of inhibitory GPCR signaling cascades. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Michael Bruchas

    Article

    Copits et al Neuron. 2021 Jun 2;109(11):1791-1809.e11

    Promoter

    EF1a

    Tags

    Venus (Cre-dependent)

    Available since

    Oct. 28, 2021

    Availability

    Academic Institutions and Nonprofits only

38. pAAV-CaMKIIa(0.4)-eOPN3-mScarlet-WPRE (AAV5)

    Viral Prep

    #125712-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV-CaMKIIa(0.4)-eOPN3-mScarlet-WPRE (#125712). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa(0.4)-eOPN3-mScarlet-WPRE plasmid DNA. CaMKIIa-driven expression of the optimized mosquito OPN3 rhodopsin in-frame with mScarlet. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Ofer Yizhar

    Article

    Mahn et al Neuron. 2021 May 10. pii: S0896-6273(21)

    Promoter

    short version of αCamKinase II promoter (0.4kb)

    Tags

    mScarlet

    Available since

    June 26, 2024

    Availability

    Academic Institutions and Nonprofits only

39. CaMKII-somBiPOLES-mCerulean (AAV Retrograde)

    Viral Prep

    #154948-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from CaMKII-somBiPOLES-mCerulean (#154948). In addition to the viral particles, you will also receive purified CaMKII-somBiPOLES-mCerulean plasmid DNA. CamKII-driven expression of soma-targeted BiPOLES for optogenetic inhibition (blue light) and activation (red light). These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Simon Wiegert

    Article

    Vierock et al Nat Commun. 2021 Jul 26;12(1):4527. doi:

    Promoter

    CaMKIIa(0.4)

    Tags

    mCerulean

    Available since

    Sept. 1, 2021

    Availability

    Academic Institutions and Nonprofits only

40. AAV-Syn-H2B-jGCaMP8m-WPRE (AAV1)

    Viral Prep

    #176748-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from AAV-Syn-H2B-jGCaMP8m-WPRE (#176748). In addition to the viral particles, you will also receive purified AAV-Syn-H2B-jGCaMP8m-WPRE plasmid DNA. Syn-driven expression of histone H2B fused to calcium sensor GCaMP8m. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    Syn

    Tags

    None

    Available since

    Feb. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

41. pAAV-S5E2-ChR2-mCherry (AAV PHP.eB)

    Viral Prep

    #135634-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV-S5E2-ChR2-mCherry (#135634). In addition to the viral particles, you will also receive purified pAAV-S5E2-ChR2-mCherry plasmid DNA. Expression of ChR2-mCherry under the control of the E2 regulatory element. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jordane Dimidschstein

    Article

    Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

    Promoter

    Tags

    mCherry

    Available since

    Oct. 28, 2021

    Availability

    Academic Institutions and Nonprofits only

42. pENN.AAV.hSyn.TurboRFP.WPRE.RBG (AAV1)

    Viral Prep

    #105552-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pENN.AAV.hSyn.TurboRFP.WPRE.RBG (#105552). In addition to the viral particles, you will also receive purified pENN.AAV.hSyn.TurboRFP.WPRE.RBG plasmid DNA. hSynapsin-driven TurboRFP. These AAV preparations are suitable purity for injection into animals.

    Depositor

    James M. Wilson

    Promoter

    Syn

    Tags

    TurboRFP

    Available since

    July 25, 2018

    Availability

    Academic Institutions and Nonprofits only

43. pAAV-CaMKIIa(0.4)-eOPN3-mScarlet-WPRE (AAV1)

    Viral Prep

    #125712-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-CaMKIIa(0.4)-eOPN3-mScarlet-WPRE (#125712). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa(0.4)-eOPN3-mScarlet-WPRE plasmid DNA. CaMKIIa-driven expression of the optimized mosquito OPN3 rhodopsin in-frame with mScarlet. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Ofer Yizhar

    Article

    Mahn et al Neuron. 2021 May 10. pii: S0896-6273(21)

    Promoter

    short version of αCamKinase II promoter (0.4kb)

    Tags

    mScarlet

    Available since

    June 26, 2024

    Availability

    Academic Institutions and Nonprofits only

44. pAAV-Ef1a-Coff/Fon-BFP (AAV8)

    Viral Prep

    #137131-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-Ef1a-Coff/Fon-BFP (#137131). In addition to the viral particles, you will also receive purified pAAV-Ef1a-Coff/Fon-BFP plasmid DNA. EF1a-driven, Flp-dependent expression of BFP (inhibited in presence of Cre). These AAV preparations are suitable purity for injection into animals.

    Depositor

    INTRSECT 2.0 Project, Karl Deisseroth

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    EF1a

    Tags

    BFP (Flp-dependent)

    Available since

    April 5, 2021

    Availability

    Academic Institutions and Nonprofits only

45. AAV-CAG-hChR2-H134R-tdTomato (AAV Retrograde)

    Viral Prep

    #28017-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from AAV-CAG-hChR2-H134R-tdTomato (#28017). In addition to the viral particles, you will also receive purified AAV-CAG-hChR2-H134R-tdTomato plasmid DNA. Humanized channelrhodopsin H134R mutant fused to tdTomato, under the control of the CAG promoter. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karel Svoboda

    Article

    Mao et al Neuron. 2011 Oct 6;72(1):111-23.

    Promoter

    CAG

    Tags

    tdTomato

    Available since

    June 20, 2017

    Availability

    Academic Institutions and Nonprofits only

46. pAAV-CAG-fDIO-mNeonGreen (AAV1)

    Viral Prep

    #99133-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-CAG-fDIO-mNeonGreen (#99133). In addition to the viral particles, you will also receive purified pAAV-CAG-fDIO-mNeonGreen plasmid DNA. CAG-driven, Flp-dependent mNeonGreen expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Viviana Gradinaru

    Article

    Chan et al Nat Neurosci. 2017 Aug;20(8):1172-1179.

    Promoter

    CAG

    Tags

    mNeonGreen (Flp-dependent)

    Available since

    Jan. 6, 2022

    Availability

    Academic Institutions and Nonprofits only

47. pAAV.CMV.HI.eGFP-Cre.WPRE.SV40 (AAV2)

    Viral Prep

    #105545-AAV2

    Purpose

    Ready-to-use AAV2 particles produced from pAAV.CMV.HI.eGFP-Cre.WPRE.SV40 (#105545). In addition to the viral particles, you will also receive purified pAAV.CMV.HI.eGFP-Cre.WPRE.SV40 plasmid DNA. CMV-driven EGFP-Cre expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    James M. Wilson

    Promoter

    HI

    Tags

    EGFP

    Available since

    Oct. 5, 2018

    Availability

    Academic Institutions and Nonprofits only

48. pAAV-EF1α-F-FLEX-mNaChBac-T2A-tdTomato (AAV8)

    Viral Prep

    #60658-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-EF1α-F-FLEX-mNaChBac-T2A-tdTomato (#60658). In addition to the viral particles, you will also receive purified pAAV-EF1α-F-FLEX-mNaChBac-T2A-tdTomato plasmid DNA. CAG-driven, Flp-dependent expression of the voltage-gated Na+ channel mNaChBac-T2A-tdTomato. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Massimo Scanziani

    Article

    Xue et al Nature. 2014 Jul 31;511(7511):596-600. d

    Promoter

    EF1α

    Tags

    None

    Available since

    Oct. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

49. pGP-AAV-GFAP-iGABASnFR2-WPRE (AAV5)

    Viral Prep

    #218871-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pGP-AAV-GFAP-iGABASnFR2-WPRE (#218871). In addition to the viral particles, you will also receive purified pGP-AAV-GFAP-iGABASnFR2-WPRE plasmid DNA. GFAP-driven expression of the improved GABA sensor iGABASnFR2 (positive change in fluorescence). These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project

    Article

    Kolb et al bioRxiv 2025.03.25.644953

    Promoter

    GFAP

    Tags

    None

    Available since

    Sept. 27, 2024

    Availability

    Academic Institutions and Nonprofits only

50. pGP-AAV-syn-FLEX-jGCaMP7f-WPRE (AAV PHP.eB)

    Viral Prep

    #104492-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pGP-AAV-syn-FLEX-jGCaMP7f-WPRE (#104492). In addition to the viral particles, you will also receive purified pGP-AAV-syn-FLEX-jGCaMP7f-WPRE plasmid DNA. Syn-driven, Cre-dependent GCaMP7f calcium sensor. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project, Douglas Kim

    Article

    Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

    Promoter

    Syn

    Tags

    None

    Available since

    Aug. 6, 2018

    Availability

    Academic Institutions and Nonprofits only