1,050 results

1. pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP (AAV8)

   Viral Prep

   #112677-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP (#112677). In addition to the viral particles, you will also receive purified pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP plasmid DNA. EF1a-driven, Cre-dependent color switch. This AAV directs expression of nuclear mCherry in the absence of Cre. In the presence of Cre, nuclear EGFP (and not mCherry) will be expressed. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Brandon Harvey

   Article

   Back et al Neuron. 2019 Feb 8. pii: S0896-6273(19)3

   Promoter

   EF1a

   Tags

   mCherry (Cre-negative cells), EGFP (Cre-positive cells)

   Available Since

   Sept. 8, 2020

   Availability

   Academic Institutions and Nonprofits only

2. pAAV-CaMKIIa-hChR2(E123A)-EYFP (AAV9)

   Viral Prep

   #35505-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-CaMKIIa-hChR2(E123A)-EYFP (#35505). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hChR2(E123A)-EYFP plasmid DNA. CaMKIIa-driven hChR2(E123A)-EYFP expression for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Article

   Mattis et al Nat Methods. 2011 Dec 18;9(2):159-72. do

   Promoter

   CaMKII

   Tags

   EYFP

   Available Since

   May 24, 2018

   Availability

   Academic Institutions and Nonprofits only

3. pGP-AAV-CAG-FLEX-jGCaMP7f-WPRE (AAV PHP.eB)

   Viral Prep

   #104496-PHPeB

   Purpose

   Ready-to-use AAV PHP.eB particles produced from pGP-AAV-CAG-FLEX-jGCaMP7f-WPRE (#104496). In addition to the viral particles, you will also receive purified pGP-AAV-CAG-FLEX-jGCaMP7f-WPRE plasmid DNA. CAG-driven, Cre-dependent jGCaMP7f calcium sensor. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

   Depositor

   GENIE Project, Douglas Kim

   Article

   Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

   Promoter

   CAG

   Available Since

   Sept. 27, 2023

   Availability

   Academic Institutions and Nonprofits only

4. pAAV-nEF-Con/Fon-ChR2(ET/TC)-EYFP (AAV8)

   Viral Prep

   #137139-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Fon-ChR2(ET/TC)-EYFP (#137139). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Fon-ChR2(ET/TC)-EYFP plasmid DNA. nEF-driven, Cre and Flp-dependent expression of ChR2(E123T/T159C)-EYFP for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   INTRSECT 2.0 Project, Karl Deisseroth

   Article

   Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

   Promoter

   nEF

   Tags

   EYFP (Cre and Flp-dependent)

   Available Since

   May 19, 2021

   Availability

   Academic Institutions and Nonprofits only

5. pAAV.hSynapsin.SF-iGluSnFR.S72A (AAV1)

   Viral Prep

   #106176-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV.hSynapsin.SF-iGluSnFR.S72A (#106176). In addition to the viral particles, you will also receive purified pAAV.hSynapsin.SF-iGluSnFR.S72A plasmid DNA. hSynapsin driven SF-iGluSnFR.S72A, glutamate sensor. The S72A mutant has lower affinity for glutamate. Slower on-rate and faster off-rate. Enhanced temporal resolution and spatial resolution. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Article

   Marvin et al Nat Methods. 2018 Nov;15(11):936-939. do

   Promoter

   Syn

   Available Since

   Feb. 25, 2019

   Availability

   Academic Institutions and Nonprofits only

6. pAAV-CAG-dLight1.2 (AAV1)

   Viral Prep

   #111069-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-CAG-dLight1.2 (#111069). In addition to the viral particles, you will also receive purified pAAV-CAG-dLight1.2 plasmid DNA. CAG-driven expression of dLight1.2 dopamine sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Lin Tian

   Article

   Patriarchi et al Science. 2018 Jun 29;360(6396). pii: sci

   Available Since

   Feb. 14, 2022

   Availability

   Academic Institutions and Nonprofits only

7. pAAV-hSyn1-Flex-mRuby2-GSG-P2A-GCaMP6s-WPRE-pA (AAV1)

   Viral Prep

   #68720-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-hSyn1-Flex-mRuby2-GSG-P2A-GCaMP6s-WPRE-pA (#68720). In addition to the viral particles, you will also receive purified pAAV-hSyn1-Flex-mRuby2-GSG-P2A-GCaMP6s-WPRE-pA plasmid DNA. Cre-dependent GCaMP6s calcium sensor and bicistronic, physically separate mRuby2 expression under a human synapsin1 promoter. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Tobias Rose, Tobias Bonhoeffer, Mark Huebener

   Article

   Rose et al Science. 2016 Jun 10;352(6291):1319-22.

   Promoter

   hSyn1-FLEX

   Tags

   mRuby2 (Cre-dependent)

   Available Since

   March 7, 2018

   Availability

   Academic Institutions and Nonprofits only

8. pOTTC1484 - pAAV SYN1 HA-hM4D(Gi) (AAV2)

   Viral Prep

   #121538-AAV2

   Purpose

   Ready-to-use AAV2 particles produced from pOTTC1484 - pAAV SYN1 HA-hM4D(Gi) (#121538). In addition to the viral particles, you will also receive purified pOTTC1484 - pAAV SYN1 HA-hM4D(Gi) plasmid DNA. Synapsin-driven, HA-tagged hM4D(Gi) for neuronal inhibition. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Christopher Richie

   Article

   Galvan et al Eur J Neurosci. 2019 May 7. doi: 10.1111

   Promoter

   Syn

   Tags

   HA

   Available Since

   Sept. 25, 2019

   Availability

   Academic Institutions and Nonprofits only

9. pAAV-hDlx-Flex-dTomato-Fishell_7 (AAV Retrograde)

   Viral Prep

   #83894-AAVrg

   Purpose

   Ready-to-use AAV Retrograde particles produced from pAAV-hDlx-Flex-dTomato-Fishell_7 (#83894). In addition to the viral particles, you will also receive purified pAAV-hDlx-Flex-dTomato-Fishell_7 plasmid DNA. hDlx-driven, Cre-dependent expression of dTomato. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Gordon Fishell

   Article

   Dimidschstein et al Nat Neurosci. 2016 Oct 31. doi: 10.1038/

   Promoter

   hDlx

   Tags

   dTomato (Cre-dependent)

   Available Since

   June 22, 2020

   Availability

   Academic Institutions and Nonprofits only

10. pZac2.1-GfaABC1D-lck-jGCaMP8m (AAV1)

    Viral Prep

    #176760-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pZac2.1-GfaABC1D-lck-jGCaMP8m (#176760). In addition to the viral particles, you will also receive purified pZac2.1-GfaABC1D-lck-jGCaMP8m plasmid DNA. GfaABC1D-driven expression of membrane-bound calcium sensor GCaMP8m. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    GfaABC1D

    Available Since

    Feb. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

11. AAV pEF1a-DIO-FLPo-WPRE-hGHpA (AAV2)

    Viral Prep

    #87306-AAV2

    Purpose

    Ready-to-use AAV2 particles produced from AAV pEF1a-DIO-FLPo-WPRE-hGHpA (#87306). In addition to the viral particles, you will also receive purified AAV pEF1a-DIO-FLPo-WPRE-hGHpA plasmid DNA. EF1a-driven, Cre dependent expression of the site-specific recombinase FlpO. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Li Zhang

    Article

    Zingg et al Neuron. 2017 Jan 4;93(1):33-47. doi: 10.

    Promoter

    EF1a

    Available Since

    Aug. 24, 2020

    Availability

    Academic Institutions and Nonprofits only

12. AAV pEF1a-DIO-FLPo-WPRE-hGHpA (AAV5)

    Viral Prep

    #87306-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from AAV pEF1a-DIO-FLPo-WPRE-hGHpA (#87306). In addition to the viral particles, you will also receive purified AAV pEF1a-DIO-FLPo-WPRE-hGHpA plasmid DNA. EF1a-driven, Cre dependent expression of the site-specific recombinase FlpO. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Li Zhang

    Article

    Zingg et al Neuron. 2017 Jan 4;93(1):33-47. doi: 10.

    Promoter

    EF1a

    Available Since

    July 22, 2020

    Availability

    Academic Institutions and Nonprofits only

13. pAAV.hSyn.CaMPARI.WPRE.SV40 (AAV9)

    Viral Prep

    #100832-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV.hSyn.CaMPARI.WPRE.SV40 (#100832). In addition to the viral particles, you will also receive purified pAAV.hSyn.CaMPARI.WPRE.SV40 plasmid DNA. Synapsin-driven, photoconvertible (irreversible green-to-red) calcium integrator. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Eric Schreiter, Loren Looger

    Article

    Fosque et al Science. 2015 Feb 13;347(6223):755-60. d

    Promoter

    Syn

    Available Since

    April 17, 2018

    Availability

    Academic Institutions and Nonprofits only

14. pAAV-S5E2-C1V1-eYFP (AAV PHP.eB)

    Viral Prep

    #135633-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV-S5E2-C1V1-eYFP (#135633). In addition to the viral particles, you will also receive purified pAAV-S5E2-C1V1-eYFP plasmid DNA. Expression of red-shifted opsin C1V1 fused to EYFP under the control of the E2 regulatory element. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jordane Dimidschstein

    Article

    Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

    Tags

    EYFP

    Available Since

    Aug. 27, 2021

    Availability

    Academic Institutions and Nonprofits only

15. pAAV-hSyn-GRAB_DA1h (AAV Retrograde)

    Viral Prep

    #113050-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-hSyn-GRAB_DA1h (#113050). In addition to the viral particles, you will also receive purified pAAV-hSyn-GRAB_DA1h plasmid DNA. Synapsin-driven expression of GRAB-DA1h dopamine sensor in neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Yulong Li

    Article

    Sun et al Cell. 2018 Jul 12;174(2):481-496.e19. do

    Promoter

    Syn

    Available Since

    Nov. 4, 2019

    Availability

    Academic Institutions and Nonprofits only

16. pENN.AAV.CB7.CI.eGFP.WPRE.rBG (AAV8)

    Viral Prep

    #105542-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pENN.AAV.CB7.CI.eGFP.WPRE.rBG (#105542). In addition to the viral particles, you will also receive purified pENN.AAV.CB7.CI.eGFP.WPRE.rBG plasmid DNA. CB7-driven eGFP. These AAV preparations are suitable purity for injection into animals.

    Depositor

    James M. Wilson

    Promoter

    CB7

    Tags

    EGFP

    Available Since

    July 25, 2018

    Availability

    Academic Institutions and Nonprofits only

17. AAV phSyn1(S)-DreO-bGHpA (AAV5)

    Viral Prep

    #50363-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from AAV phSyn1(S)-DreO-bGHpA (#50363). In addition to the viral particles, you will also receive purified AAV phSyn1(S)-DreO-bGHpA plasmid DNA. hSyn-driven Dre recombinase expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Hongkui Zeng

    Article

    Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

    Promoter

    Syn

    Available Since

    May 29, 2019

    Availability

    Academic Institutions and Nonprofits only

18. pAAV-CAG-eYFP (AAV PHP.eB)

    Viral Prep

    #104055-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV-CAG-eYFP (#104055). In addition to the viral particles, you will also receive purified pAAV-CAG-eYFP plasmid DNA. CAG-driven eYFP expression control. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Viviana Gradinaru

    Article

    Challis et al Nat Protoc. 2019 Feb;14(2):379-414. doi:

    Promoter

    CAG

    Tags

    EYFP

    Available Since

    June 13, 2023

    Availability

    Academic Institutions and Nonprofits only

19. pAAV-synapsin-HaloCaMP1a-EGFP (AAV1)

    Viral Prep

    #138327-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-synapsin-HaloCaMP1a-EGFP (#138327). In addition to the viral particles, you will also receive purified pAAV-synapsin-HaloCaMP1a-EGFP plasmid DNA. Synapsin-driven HaloCaMP1a, a far-red calcium sensor, fused to EGFP. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Eric Schreiter

    Article

    Deo et al Nat Chem Biol. 2021 Jun;17(6):718-723. d

    Promoter

    Syn

    Tags

    EGFP

    Available Since

    Sept. 15, 2021

    Availability

    Academic Institutions and Nonprofits only

20. pSMAL-CellTag-V2 (Concentrated Lentiviral Prep)

    Viral Prep

    #115644-LVC

    Purpose

    Ready-to-use Concentrated Lentiviral Prep particles produced from pSMAL-CellTag-V2 (#115644). In addition to the viral particles, you will also receive purified pSMAL-CellTag-V2 plasmid DNA. Ready-to-use lentiviral particles carrying version 2 of the CellTag barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics.

    Depositor

    Samantha Morris

    Article

    Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

    Promoter

    Minimal CMV

    Tags

    EGFP

    Available Since

    Oct. 29, 2019

    Availability

    Academic Institutions and Nonprofits only

21. AiP13987: pAAV-AiE0452h_3xC2-minBG-jRGECO1a-WPRE3-BGHpA (Alias: CN3987) (AAV PHP.eB)

    Viral Prep

    #214851-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from AiP13987: pAAV-AiE0452h_3xC2-minBG-jRGECO1a-WPRE3-BGHpA (Alias: CN3987) (#214851). In addition to the viral particles, you will also receive purified AiP13987: pAAV-AiE0452h_3xC2-minBG-jRGECO1a-WPRE3-BGHpA (Alias: CN3987) plasmid DNA. minBG-driven expression of jRGECO1a in striatal indirect pathway medium spiny neurons (D2 MSNs). These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Available Since

    Jan. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

22. pAAV-CAG-DIO-PPO-Venus (AAV5)

    Viral Prep

    #139504-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV-CAG-DIO-PPO-Venus (#139504). In addition to the viral particles, you will also receive purified pAAV-CAG-DIO-PPO-Venus plasmid DNA. CAG-driven, Cre-dependent expression of Venus-tagged parapinopsin. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Michael Bruchas

    Article

    Copits et al Neuron. 2021 Jun 2;109(11):1791-1809.e11

    Promoter

    CAG

    Tags

    Venus

    Available Since

    April 10, 2024

    Availability

    Academic Institutions and Nonprofits only

23. pGP-AAV-syn-flex-iGABASnFR2(no bind)-WPRE (AAV1)

    Viral Prep

    #218879-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pGP-AAV-syn-flex-iGABASnFR2(no bind)-WPRE (#218879). In addition to the viral particles, you will also receive purified pGP-AAV-syn-flex-iGABASnFR2(no bind)-WPRE plasmid DNA. Syn-driven, Cre-dependent expression of the improved GABA sensor control iGABASnFR2(no bind) (no change in fluorescence). These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project

    Article

    Kolb et al bioRxiv 2025.03.25.644953

    Promoter

    Syn

    Available Since

    Oct. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

24. pGP-AAV-syn-jGCaMP7c variant 1513-WPRE (AAV1)

    Viral Prep

    #105321-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pGP-AAV-syn-jGCaMP7c variant 1513-WPRE (#105321). In addition to the viral particles, you will also receive purified pGP-AAV-syn-jGCaMP7c variant 1513-WPRE plasmid DNA. Synapsin-driven jGCaMP7c expression. jGCaMP7c exhibits high contrast between peak fluorescence and resting fluorescence. It is useful for activity imaging of large populations of densely-labeled neurons because background fluorescence from inactive neurons is reduced. These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project, Douglas Kim

    Article

    Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

    Promoter

    Syn

    Available Since

    July 12, 2019

    Availability

    Academic Institutions and Nonprofits only

25. pAAV.hSyn.Flex.iGluSnFr.WPRE.SV40 (AAV9)

    Viral Prep

    #98931-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV.hSyn.Flex.iGluSnFr.WPRE.SV40 (#98931). In addition to the viral particles, you will also receive purified pAAV.hSyn.Flex.iGluSnFr.WPRE.SV40 plasmid DNA. Synapsin-driven, Cre-dependent, iGluSnFr glutamate sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Marvin et al Nat Methods. 2013 Feb;10(2):162-70. doi:

    Promoter

    Syn

    Available Since

    March 30, 2018

    Availability

    Academic Institutions and Nonprofits only

26. pAAV-S5E6-dTom-nlsdTom (AAV1)

    Viral Prep

    #135641-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-S5E6-dTom-nlsdTom (#135641). In addition to the viral particles, you will also receive purified pAAV-S5E6-dTom-nlsdTom plasmid DNA. Bicistronic expression of dTomato and nuclear-targeted dTomato in VIP cortical interneurons under the control of the E6 regulatory element. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jordane Dimidschstein

    Article

    Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

    Tags

    dTomato

    Available Since

    Feb. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

27. pAAV-GFAP-HA-rM3D(Gs)-IRES-mCitrine (AAV5)

    Viral Prep

    #50472-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV-GFAP-HA-rM3D(Gs)-IRES-mCitrine (#50472). In addition to the viral particles, you will also receive purified pAAV-GFAP-HA-rM3D(Gs)-IRES-mCitrine plasmid DNA. GFAP-driven HA-tagged rM3D(Gs) and bicistronic mCitrine expression, for chemogenetic excitation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Promoter

    GFAP

    Tags

    mCitrine

    Available Since

    Jan. 6, 2022

    Availability

    Academic Institutions and Nonprofits only

28. pAAV.CMV.LacZ.bGH (AAV8)

    Viral Prep

    #105531-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV.CMV.LacZ.bGH (#105531). In addition to the viral particles, you will also receive purified pAAV.CMV.LacZ.bGH plasmid DNA. CMV-driven LacZ expression control. These AAV preparations are suitable purity for injection into animals.

    Depositor

    James M. Wilson

    Promoter

    CMV

    Tags

    LacZ

    Available Since

    June 29, 2018

    Availability

    Academic Institutions and Nonprofits only

29. pAAV.hSynap-FLEX.SF-iGluSnFR.A184V (AAV1)

    Viral Prep

    #106181-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV.hSynap-FLEX.SF-iGluSnFR.A184V (#106181). In addition to the viral particles, you will also receive purified pAAV.hSynap-FLEX.SF-iGluSnFR.A184V plasmid DNA. Synapsin-driven, Cre-dependent expression of glutamate sensor iGluSnFR (medium affinity). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Marvin et al Nat Methods. 2018 Nov;15(11):936-939. do

    Promoter

    Syn

    Available Since

    March 19, 2021

    Availability

    Academic Institutions and Nonprofits only

30. pAAV-CAG-NIR-GECO2G (AAV2)

    Viral Prep

    #159605-AAV2

    Purpose

    Ready-to-use AAV2 particles produced from pAAV-CAG-NIR-GECO2G (#159605). In addition to the viral particles, you will also receive purified pAAV-CAG-NIR-GECO2G plasmid DNA. CAG-driven expression of the near-infrared calcium indicator NIR-GECO2G. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Robert Campbell

    Article

    Qian et al PLoS Biol. 2020 Nov 24;18(11):e3000965.

    Promoter

    CAG

    Available Since

    Dec. 18, 2024

    Availability

    Academic Institutions and Nonprofits only