1,189 results

Find materials created at Addgene, including empty backbones, control vectors, viral packaging and expression plasmids, and more.

Addgene's curated collection of plasmids for cancer research, organized by signaling pathway.

Addgene's plasmids for the mTOR pathway. enhanced signaling of mTOR, a key metabolic regulator, correlates with poor prognosis in many cancers.

Addgene's collection of plasmids for the p53 pathway. p53 is a transcription factor and tumor suppressor activated by cellular stress.

Addgene's collection of plasmids for the Ras pathway. Ras is a small GTPase and constitutively active Ras is the most common oncogene in human cancer.

CRISPR plasmids available at Addgene. Search by species and CRISPR function.

CRISPR plasmids for activating or upregulating gene expression in various model organisms.

CRISPR plasmids for precisely editing DNA bases without inducing a DNA break.

CRISPR plasmids that create double strand breaks in DNA.

CRISPR plasmids with dCas9 fused to FokI for creating double-strand breaks (DSBs).

Empty gRNA expression vectors for insertion of custom gRNA target sequences.

CRISPR plasmids for targeted epigenetic modification, including histone acetylation/demethylation, and cytosine methylation/demethylation.

CRISPR plasmids for transcriptional repression of target genes.

CRISPR nickase plasmids for the generation of single-strand breaks.

CRISPR plasmids for endogenous tagging of your gene of interest.

Catalytically inactive CRISPR plasmids for purification of target loci.

CRISPR plasmids based on Cas13 designed to precisely edit RNA targets.

CRISPR plasmids for targeting RNA sequences, which include the enzymes C2c2/Cas13a and Cas13b.

CRISPR/Cas plasmids for labeling and visualization of genomic loci.