Viral Vectors 101: AAV Serotypes and Tissue Tropism
Type
Blog Post
...Brian O’Neill and Ina Ersing for contributing their expertise!
This post was originally published in January...administered systemically, without causing disease? Recombinant adeno-associated viral vectors, or rAAVs, can...Carboxypeptidase D (CPD), also called AAVR25
AAV9
Terminal N-linked galactose3
AAV receptor (AAVR)2
Laminin...found to transduce skeletal muscle, cardiac, and retinal cells (Issa et al., 2023).
AAV2
Despite being isolated...tropism, including liver, muscle, lung, CNS, kidney, retinal, and pancreatic cells (Ahuja et al., 2025; Issa...cardiac, pancreas, smooth muscle, CNS, kidney, and retinal cells (Issa et al., 2023; Wu, Asokan, et al., 2006...transduce liver, skeletal muscle, pancreatic, and retinal cells (Issa et al., 2023).
AAV11
AAV11 is a relatively...