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Addgene
Showing: 41 - 60 of 65 results
  1. All Antibodies

    Type
    Collection
    ...undergo application-specific validation and quality control by Addgene as well as by our trusted partner labs...
  2. Zhang Lab CRISPR Page

    Type
    Collection
    ...recombinase, and Kras G12D HDR template 60225 : control for AAV-KPL; sgRNA targeted to LacZ, plus luciferase...within the mouse genome. This plasmid is used as a control for AAV-KPL. #60226 - AAV:ITR-U6-sgRNA(backbone...targeting the neuronal-specific gene NeuN. As a control they designed an sgRNA targeting LacZ, which is...
  3. Chemogenetics Plasmids

    Type
    Collection
    ...specific small molecules, allowing a scientist to control signaling within cells expressing these engineered...
  4. AAV Molecular Tools

    Type
    Collection
    ... These AAV encode tetracycline-inducible tools/controls and tetracycline transactivators that can be used...
  5. CRISPR References and Information

    Type
    Collection
    ... packaging plasmids: pVSVg , psPAX2 ; positive control: CMV-EGFP PDF 2.3 MB Zhang GeCKO pooled library...lentiGuide-Puro packaging plasmids: pVSVg , psPAX2 positive control: CMV-EGFP Kits are also available (mouse or human...
  6. SARS-CoV-2 Pseudotyped Virus

    Type
    Collection
    ...Description Mutations Industry PI Due to export control regulations, MERS and SARS-CoV materials are available...
  7. Fluorescent Protein Guide: Biosensors

    Type
    Collection
    ... with different binding affinities or negative-control constructs used to characterize the sensor's behavior... GCaMP6f in PV cortical interneurons under the control of the E2 regulatory element Viral manipulation...in forebrain GABA-ergic interneurons under the control of the mDlx enhancer A viral strategy for targeting...Autophagic Flux Probe that Releases an Internal Control. Mol Cell. 2016 Nov 17;64(4):835-849. Noboru Mizushima...expression of pH sensitive mt-mKeima) Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective...molecular tension sensors reveal extension-based control of vinculin loading. eLife. 2018 Jul 19;7. pii:...
  8. COVID-19 Resources

    Type
    Collection
    ...available and more are currently undergoing quality control analysis in our lab and will be made available ... Plasmid Description Industry PI Due to export control regulations, MERS and SARS-CoV materials are available...
  9. Recombinases AAV Preps

    Type
    Collection
    ...site-specific recombinases, which can be used to control gene expression. See our Cre-lox Plasmids page ...
  10. Optogenetics AAV Preps

    Type
    Collection
    ...Optogenetics AAV Optogenetic tools can be used to control cell activity in living tissue with light. Optogenetics...Optogenetics is typically used in neuroscience to control electrical potentials in neurons. See our Optogenetics...
  11. Distribution to Industry

    Type
    Collection
    ...undergo application-specific validation and quality control by Addgene as well as by our trusted partner labs...
  12. CRISPR Guide

    Type
    Collection
    ...-occurring Acr (Anti-CRISPR) proteins can help control CRISPR activity. Acr proteins have evolved in phages...LmoCas9 and SpCas9. Acr proteins can be used to control both when and where genome editing happens. CASANOVA...Dominik Niopek’s lab , is a way to optogenetically control genome editing by fusing the anti-CRISPR protein...photosensitive LOV2 domain . Several labs have also controlled Acr activity with endogenous cell-type specific...have also been used in in vivo RNA imaging or to control alternative splicing. Figure 13: Overview of RNA...Engineered anti-CRISPR proteins for optogenetic control of CRISPR–Cas9. Nature Methods , 15 (11), 924–927...homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery. eLife . 3 e04766...
  13. Antibody Plasmid Collection

    Type
    Collection
    ...undergo application-specific validation and quality control by Addgene as well as by our trusted partner labs...
  14. The Pleiades Promoter Project

    Type
    Collection
    ...MiniPromoter Source Gene Construct Reporter Negative Control N/A pEMS1312 cre N/A pEMS1301 cre/EGFP/NLS N/A ...EGFP/NLS N/A pEMS1313 intron-lacZ/NLS Positive Control CAG promoter pEMS1293 cre CAG promoter pEMS1164...
  15. Plant Plasmids and Resources

    Type
    Collection
    ... and experimental resources that relate to the control of gene expression in the grasses. OpenPlant Synthetic...
  16. Kazuhiro Oka Lentiviral Vectors

    Type
    Collection
    ...vectors to express your gene of interest under the control of a variety of promoters. Professor Oka and the...
  17. Lentivirus Plasmids

    Type
    Collection
    ...pLVTHM 2nd EF-1a-driven GFP and shRNA under the control of a tet-responsive H1 promoter Trono 11651 pLVUT-tTR-KRAB...
  18. Neurodegeneration Research Collection

    Type
    Collection
    ...neurons in the substantia nigra, one of the movement control centers in the brain. The cause of this neuron ...Symptoms include changes in behavior and emotion, uncontrolled movements, memory deficits, as well as difficulty...
Showing: 41 - 60 of 65 results