pRRLSIN.cPPT.PGK-GFP.WPRE Citations (158)
Originally described in: Trono Lab Misc PlasmidsUnpublished
Articles Citing pRRLSIN.cPPT.PGK-GFP.WPRE
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| Hypoxic preconditioning enhances the benefit of cardiac progenitor cell therapy for treatment of myocardial infarction by inducing CXCR4 expression. Tang YL, Zhu W, Cheng M, Chen L, Zhang J, Sun T, Kishore R, Phillips MI, Losordo DW, Qin G. Circ Res. 2009 May 22;104(10):1209-16. doi: 10.1161/CIRCRESAHA.109.197723. Epub 2009 Apr 30. PubMed |
| Ex vivo expansion and lentiviral transduction of Macaca nemestrina CD4+ T cells. Munoz NM, Trobridge GD, Kiem HP. J Med Primatol. 2009 Dec;38(6):438-43. doi: 10.1111/j.1600-0684.2009.00383.x. Epub 2009 Sep 28. PubMed |
| Reversibly immortalized human olfactory ensheathing glia from an elderly donor maintain neuroregenerative capacity. Lim F, Martin-Bermejo MJ, Garcia-Escudero V, Gallego-Hernandez MT, Garcia-Gomez A, Rabano A, Diaz-Nido J, Avila J, Moreno-Flores MT. Glia. 2010 Apr;58(5):546-58. doi: 10.1002/glia.20944. PubMed |
| Prevention of senescence progression in reversibly immortalized human ensheathing glia permits their survival after deimmortalization. García-Escudero V, García-Gómez A, Gargini R, Martín-Bermejo MJ, Langa E, de Yébenes JG, Delicado A, Avila J, Moreno-Flores MT, Lim F. Mol Ther. 2010 Feb . 18(2):394-403. PubMed |
| An emerging player in the adaptive immune response: microRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes. Curtale G, Citarella F, Carissimi C, Goldoni M, Carucci N, Fulci V, Franceschini D, Meloni F, Barnaba V, Macino G. Blood. 2010 Jan 14. 115(2):265-73. PubMed |
| Cocal-pseudotyped lentiviral vectors resist inactivation by human serum and efficiently transduce primate hematopoietic repopulating cells. Trobridge GD, Wu RA, Hansen M, Ironside C, Watts KL, Olsen P, Beard BC, Kiem HP. Mol Ther. 2010 Apr;18(4):725-33. doi: 10.1038/mt.2009.282. Epub 2009 Dec 8. PubMed |
| Recreation of the terminal events in physiological integrin activation. Ye F, Hu G, Taylor D, Ratnikov B, Bobkov AA, McLean MA, Sligar SG, Taylor KA, Ginsberg MH. J Cell Biol. 2010 Jan 11;188(1):157-73. doi: 10.1083/jcb.200908045. Epub 2010 Jan 4. PubMed |
| A neuroregenerative human ensheathing glia cell line with conditional rapid growth. Garcia-Escudero V, Gargini R, Gallego-Hernandez MT, Garcia-Gomez A, Martin-Bermejo MJ, Simon D, Delicado A, Moreno-Flores MT, Avila J, Lim F. Cell Transplant. 2011;20(2):153-66. doi: 10.3727/096368910X522108. Epub 2010 Aug 18. PubMed |
| Gene therapy of canine leukocyte adhesion deficiency using lentiviral vectors with human CD11b and CD18 promoters driving canine CD18 expression. Hunter MJ, Tuschong LM, Fowler CJ, Bauer TR Jr, Burkholder TH, Hickstein DD. Mol Ther. 2011 Jan;19(1):113-21. doi: 10.1038/mt.2010.203. Epub 2010 Sep 21. PubMed |
| Combining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon alpha-induced early antiviral signalling. Maiwald T, Schneider A, Busch H, Sahle S, Gretz N, Weiss TS, Kummer U, Klingmuller U. FEBS J. 2010 Nov;277(22):4741-54. doi: 10.1111/j.1742-4658.2010.07880.x. Epub 2010 Oct 21. PubMed |
| Development of B-lineage predominant lentiviral vectors for use in genetic therapies for B cell disorders. Sather BD, Ryu BY, Stirling BV, Garibov M, Kerns HM, Humblet-Baron S, Astrakhan A, Rawlings DJ. Mol Ther. 2011 Mar;19(3):515-25. doi: 10.1038/mt.2010.259. Epub 2010 Dec 7. PubMed |
| Engineering exon-skipping vectors expressing U7 snRNA constructs for Duchenne muscular dystrophy gene therapy. Goyenvalle A, Davies KE. Methods Mol Biol. 2011;709:179-96. doi: 10.1007/978-1-61737-982-6_11. PubMed |
| Gene therapy for canine leukocyte adhesion deficiency with lentiviral vectors using the murine stem cell virus and human phosphoglycerate kinase promoters. Hunter MJ, Zhao H, Tuschong LM, Bauer TR Jr, Burkholder TH, Persons DA, Hickstein DD. Hum Gene Ther. 2011 Jun;22(6):689-96. doi: 10.1089/hum.2010.130. Epub 2011 Apr 11. PubMed |
Tracking genome engineering outcome at individual DNA breakpoints.
Certo MT, Ryu BY, Annis JE, Garibov M, Jarjour J, Rawlings DJ, Scharenberg AM.
Nat Methods. 2011 Jul 10;8(8):671-6. doi: 10.1038/nmeth.1648.
PubMed
Associated Plasmids |
| Induced autophagy reduces virus output in dengue infected monocytic cells. Panyasrivanit M, Greenwood MP, Murphy D, Isidoro C, Auewarakul P, Smith DR. Virology. 2011 Sep 15;418(1):74-84. doi: 10.1016/j.virol.2011.07.010. Epub 2011 Aug 2. PubMed |
| Daedalus: a robust, turnkey platform for rapid production of decigram quantities of active recombinant proteins in human cell lines using novel lentiviral vectors. Bandaranayake AD, Correnti C, Ryu BY, Brault M, Strong RK, Rawlings DJ. Nucleic Acids Res. 2011 Nov;39(21):e143. doi: 10.1093/nar/gkr706. Epub 2011 Sep 12. PubMed |
| A role for SMN exon 7 splicing in the selective vulnerability of motor neurons in spinal muscular atrophy. Ruggiu M, McGovern VL, Lotti F, Saieva L, Li DK, Kariya S, Monani UR, Burghes AH, Pellizzoni L. Mol Cell Biol. 2012 Jan;32(1):126-38. doi: 10.1128/MCB.06077-11. Epub 2011 Oct 28. PubMed |
| Remodeling of the epitope repertoire of a candidate idiotype vaccine by targeting to lysosomal degradation in dendritic cells. Martorelli D, Coppotelli G, Muraro E, Dolcetti R, Masucci MG. Cancer Immunol Immunother. 2012 Jun;61(6):881-92. doi: 10.1007/s00262-011-1157-5. Epub 2011 Nov 17. PubMed |
| Efficient reprogramming of human cord blood CD34+ cells into induced pluripotent stem cells with OCT4 and SOX2 alone. Meng X, Neises A, Su RJ, Payne KJ, Ritter L, Gridley DS, Wang J, Sheng M, Lau KH, Baylink DJ, Zhang XB. Mol Ther. 2012 Feb;20(2):408-16. doi: 10.1038/mt.2011.258. Epub 2011 Nov 22. PubMed |
Chromatin-modifying enzymes as modulators of reprogramming.
Onder TT, Kara N, Cherry A, Sinha AU, Zhu N, Bernt KM, Cahan P, Marcarci BO, Unternaehrer J, Gupta PB, Lander ES, Armstrong SA, Daley GQ.
Nature. 2012 Mar 4;483(7391):598-602. doi: 10.1038/nature10953.
PubMed
Associated Plasmids |
| Engineering U7snRNA gene to reframe transcripts. Goyenvalle A. Methods Mol Biol. 2012;867:259-71. doi: 10.1007/978-1-61779-767-5_17. PubMed |
| Excitotoxicity downregulates TrkB.FL signaling and upregulates the neuroprotective truncated TrkB receptors in cultured hippocampal and striatal neurons. Gomes JR, Costa JT, Melo CV, Felizzi F, Monteiro P, Pinto MJ, Inacio AR, Wieloch T, Almeida RD, Graos M, Duarte CB. J Neurosci. 2012 Mar 28;32(13):4610-22. doi: 10.1523/JNEUROSCI.0374-12.2012. PubMed |
| Talin activates integrins by altering the topology of the beta transmembrane domain. Kim C, Ye F, Hu X, Ginsberg MH. J Cell Biol. 2012 May 28;197(5):605-11. doi: 10.1083/jcb.201112141. PubMed |
Coupling endonucleases with DNA end-processing enzymes to drive gene disruption.
Certo MT, Gwiazda KS, Kuhar R, Sather B, Curinga G, Mandt T, Brault M, Lambert AR, Baxter SK, Jacoby K, Ryu BY, Kiem HP, Gouble A, Paques F, Rawlings DJ, Scharenberg AM.
Nat Methods. 2012 Oct;9(10):973-5. doi: 10.1038/nmeth.2177. Epub 2012 Sep 2.
PubMed
Associated Plasmids |
| An SMN-dependent U12 splicing event essential for motor circuit function. Lotti F, Imlach WL, Saieva L, Beck ES, Hao le T, Li DK, Jiao W, Mentis GZ, Beattie CE, McCabe BD, Pellizzoni L. Cell. 2012 Oct 12;151(2):440-54. doi: 10.1016/j.cell.2012.09.012. PubMed |
| The transporter ABCB7 is a mediator of the phenotype of acquired refractory anemia with ring sideroblasts. Nikpour M, Scharenberg C, Liu A, Conte S, Karimi M, Mortera-Blanco T, Giai V, Fernandez-Mercado M, Papaemmanuil E, Hogstrand K, Jansson M, Vedin I, Stephen Wainscoat J, Campbell P, Cazzola M, Boultwood J, Grandien A, Hellstrom-Lindberg E. Leukemia. 2013 Apr;27(4):889-96. doi: 10.1038/leu.2012.298. Epub 2012 Oct 16. PubMed |
Generation of human cell lines using lentiviral-mediated genetic engineering.
Salmon P.
Methods Mol Biol. 2013;945:417-48. doi: 10.1007/978-1-62703-125-7_25.
PubMed
Associated Plasmids |
| A systematic approach to the establishment and characterization of endothelial progenitor cells for gene therapy. Werling NJ, Thorpe R, Zhao Y. Hum Gene Ther Methods. 2013 Jun;24(3):171-84. doi: 10.1089/hgtb.2012.146. Epub 2013 Apr 30. PubMed |
| Endogenous IL-1alpha is a chromatin-associated protein in mouse macrophages. Lamacchia C, Rodriguez E, Palmer G, Gabay C. Cytokine. 2013 Aug;63(2):135-44. doi: 10.1016/j.cyto.2013.04.010. Epub 2013 May 14. PubMed |
| Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming. Christoforou N, Chellappan M, Adler AF, Kirkton RD, Wu T, Addis RC, Bursac N, Leong KW. PLoS One. 2013 May 21;8(5):e63577. doi: 10.1371/journal.pone.0063577. Print 2013. PubMed |
| Technical advance: actin CytoFRET, a novel FRET flow cytometry method for detection of actin dynamics in resting and activated T cell. Larbret F, Dubois N, Brau F, Guillemot E, Mahiddine K, Tartare-Deckert S, Verhasselt V, Deckert M. J Leukoc Biol. 2013 Sep;94(3):531-9. doi: 10.1189/jlb.0113022. Epub 2013 Jun 21. PubMed |
| A cell system for phenotypic screening of modifiers of SMN2 gene expression and function. Li DK, Tisdale S, Espinoza-Derout J, Saieva L, Lotti F, Pellizzoni L. PLoS One. 2013 Aug 15;8(8):e71965. doi: 10.1371/journal.pone.0071965. eCollection 2013. PubMed |
| A high-capacity cell macroencapsulation system supporting the long-term survival of genetically engineered allogeneic cells. Lathuiliere A, Cosson S, Lutolf MP, Schneider BL, Aebischer P. Biomaterials. 2014 Jan;35(2):779-91. doi: 10.1016/j.biomaterials.2013.09.071. Epub 2013 Oct 5. PubMed |
| Genetic engineering of cell lines using lentiviral vectors to achieve antibody secretion following encapsulated implantation. Lathuiliere A, Bohrmann B, Kopetzki E, Schweitzer C, Jacobsen H, Moniatte M, Aebischer P, Schneider BL. Biomaterials. 2014 Jan;35(2):792-802. PubMed |
| Inhibition of stearoyl-coA desaturase selectively eliminates tumorigenic Nanog-positive cells: improving the safety of iPS cell transplantation to myocardium. Zhang L, Pan Y, Qin G, Chen L, Chatterjee TK, Weintraub NL, Tang Y. Cell Cycle. 2014;13(5):762-71. doi: 10.4161/cc.27677. Epub 2014 Jan 6. PubMed |
| MiR-92a regulates viability and angiogenesis of endothelial cells under oxidative stress. Zhang L, Zhou M, Qin G, Weintraub NL, Tang Y. Biochem Biophys Res Commun. 2014 Apr 18;446(4):952-8. doi: 10.1016/j.bbrc.2014.03.035. Epub 2014 Mar 17. PubMed |
| Assessing in vitro stem-cell function and tracking engraftment of stem cells in ischaemic hearts by using novel iRFP gene labelling. Wang Y, Zhou M, Wang X, Qin G, Weintraub NL, Tang Y. J Cell Mol Med. 2014 Sep;18(9):1889-94. doi: 10.1111/jcmm.12321. Epub 2014 Jun 9. PubMed |
| MT5-MMP regulates adult neural stem cell functional quiescence through the cleavage of N-cadherin. Porlan E, Marti-Prado B, Morante-Redolat JM, Consiglio A, Delgado AC, Kypta R, Lopez-Otin C, Kirstein M, Farinas I. Nat Cell Biol. 2014 Jul;16(7):629-38. doi: 10.1038/ncb2993. Epub 2014 Jun 22. PubMed |
| Lentiviral gene transduction of mouse and human hematopoietic stem cells. van Til NP, Wagemaker G. Methods Mol Biol. 2014;1185:311-9. doi: 10.1007/978-1-4939-1133-2_21. PubMed |
| Isolation of contractile cardiomyocytes from human pluripotent stem-cell-derived cardiomyogenic cultures using a human NCX1-EGFP reporter. Ovchinnikov DA, Hidalgo A, Yang SK, Zhang X, Hudson J, Mazzone SB, Chen C, Cooper-White JJ, Wolvetang EJ. Stem Cells Dev. 2015 Jan 1;24(1):11-20. doi: 10.1089/scd.2014.0195. PubMed |
| MYC activates stem-like cell potential in hepatocarcinoma by a p53-dependent mechanism. Akita H, Marquardt JU, Durkin ME, Kitade M, Seo D, Conner EA, Andersen JB, Factor VM, Thorgeirsson SS. Cancer Res. 2014 Oct 15;74(20):5903-13. doi: 10.1158/0008-5472.CAN-14-0527. Epub 2014 Sep 4. PubMed |
U2AF1 mutations alter splice site recognition in hematological malignancies.
Ilagan JO, Ramakrishnan A, Hayes B, Murphy ME, Zebari AS, Bradley P, Bradley RK.
Genome Res. 2015 Jan;25(1):14-26. doi: 10.1101/gr.181016.114. Epub 2014 Sep 29.
PubMed
Associated Plasmids |
Rapid neurogenesis through transcriptional activation in human stem cells.
Busskamp V, Lewis NE, Guye P, Ng AH, Shipman SL, Byrne SM, Sanjana NE, Murn J, Li Y, Li S, Stadler M, Weiss R, Church GM.
Mol Syst Biol. 2014 Nov 17;10(11):760. doi: 10.15252/msb.20145508.
PubMed
Associated Plasmids |
| TRAF2 recruitment via T61 in CD30 drives NFkappaB activation and enhances hESC survival and proliferation. Thakar NY, Ovchinnikov DA, Hastie ML, Kobe B, Gorman JJ, Wolvetang EJ. Mol Biol Cell. 2015 Mar 1;26(5):993-1006. doi: 10.1091/mbc.E14-08-1290. Epub 2015 Jan 7. PubMed |
| Potent degradation of neuronal miRNAs induced by highly complementary targets. de la Mata M, Gaidatzis D, Vitanescu M, Stadler MB, Wentzel C, Scheiffele P, Filipowicz W, Grosshans H. EMBO Rep. 2015 Apr;16(4):500-11. doi: 10.15252/embr.201540078. Epub 2015 Feb 27. PubMed |
| Osmoregulation requires brain expression of the renal Na-K-2Cl cotransporter NKCC2. Konopacka A, Qiu J, Yao ST, Greenwood MP, Greenwood M, Lancaster T, Inoue W, Mecawi Ade S, Vechiato FM, de Lima JB, Coletti R, Hoe SZ, Martin A, Lee J, Joseph M, Hindmarch C, Paton J, Antunes-Rodrigues J, Bains J, Murphy D. J Neurosci. 2015 Apr 1;35(13):5144-55. doi: 10.1523/JNEUROSCI.4121-14.2015. PubMed |
| Single-step cloning-screening method: a new tool for developing and studying high-titer viral vector producer cells. Rodrigues AF, Formas-Oliveira AS, Guerreiro MR, Tomas HA, Alves PM, Coroadinha AS. Gene Ther. 2015 Sep;22(9):685-95. doi: 10.1038/gt.2015.44. Epub 2015 May 4. PubMed |
| Systematic Comparison and Validation of Quantitative Real-Time PCR Methods for the Quantitation of Adeno-Associated Viral Products. Werling NJ, Satkunanathan S, Thorpe R, Zhao Y. Hum Gene Ther Methods. 2015 Jun;26(3):82-92. doi: 10.1089/hgtb.2015.013. Epub 2015 Jun 9. PubMed |
| Lentiviral transduction of mammary epithelial cells. Iggo R, Richard E. Methods Mol Biol. 2015;1293:137-60. doi: 10.1007/978-1-4939-2519-3_8. PubMed |
| Scalable Electrophysiological Investigation of iPS Cell-Derived Cardiomyocytes Obtained by a Lentiviral Purification Strategy. Friedrichs S, Malan D, Voss Y, Sasse P. J Clin Med. 2015 Jan 8;4(1):102-23. doi: 10.3390/jcm4010102. PubMed |
| MiR-146b Mediates Endotoxin Tolerance in Human Phagocytes. Renzi TA, Rubino M, Gornati L, Garlanda C, Locati M, Curtale G. Mediators Inflamm. 2015;2015:145305. doi: 10.1155/2015/145305. Epub 2015 Sep 14. PubMed |
| Transduction of an immortalized olfactory ensheathing glia cell line with the green fluorescent protein (GFP) gene: Evaluation of its neuroregenerative capacity as a proof of concept. Plaza N, Simon D, Sierra J, Moreno-Flores MT. Neurosci Lett. 2016 Jan 26;612:25-31. doi: 10.1016/j.neulet.2015.12.001. Epub 2015 Dec 3. PubMed |
| Rasd1, a small G protein with a big role in the hypothalamic response to neuronal activation. Greenwood MP, Greenwood M, Mecawi AS, Antunes-Rodrigues J, Paton JF, Murphy D. Mol Brain. 2016 Jan 7;9(1):1. doi: 10.1186/s13041-015-0182-2. PubMed |
| T-cell libraries allow simple parallel generation of multiple peptide-specific human T-cell clones. Theaker SM, Rius C, Greenshields-Watson A, Lloyd A, Trimby A, Fuller A, Miles JJ, Cole DK, Peakman M, Sewell AK, Dolton G. J Immunol Methods. 2016 Jan 27. pii: S0022-1759(16)30014-X. doi: 10.1016/j.jim.2016.01.014. PubMed |
| A subcutaneous cellular implant for passive immunization against amyloid-beta reduces brain amyloid and tau pathologies. Lathuiliere A, Laversenne V, Astolfo A, Kopetzki E, Jacobsen H, Stampanoni M, Bohrmann B, Schneider BL, Aebischer P. Brain. 2016 May;139(Pt 5):1587-604. doi: 10.1093/brain/aww036. Epub 2016 Mar 8. PubMed |
| Stable and Efficient Genetic Modification of Cells in the Adult Mouse V-SVZ for the Analysis of Neural Stem Cell Autonomous and Non-autonomous Effects. Porlan E, Marti-Prado B, Consiglio A, Farinas I. J Vis Exp. 2016 Feb 17;(108). doi: 10.3791/53282. PubMed |
| Development of Third-generation Cocal Envelope Producer Cell Lines for Robust Lentiviral Gene Transfer into Hematopoietic Stem Cells and T-cells. Humbert O, Gisch DW, Wohlfahrt ME, Adams AB, Greenberg PD, Schmitt TM, Trobridge GD, Kiem HP. Mol Ther. 2016 May 24. doi: 10.1038/mt.2016.70. PubMed |
| CD99 isoforms regulate CD1a expression in human monocyte-derived DCs through ATF-2/CREB-1 phosphorylation. Mahiddine K, Mallavialle A, Bziouech H, Larbret F, Bernard A, Bernard G. Eur J Immunol. 2016 Jun;46(6):1460-71. doi: 10.1002/eji.201546143. Epub 2016 May 6. PubMed |
| Engineering of Isogenic Cells Deficient for MR1 with a CRISPR/Cas9 Lentiviral System: Tools To Study Microbial Antigen Processing and Presentation to Human MR1-Restricted T Cells. Laugel B, Lloyd A, Meermeier EW, Crowther MD, Connor TR, Dolton G, Miles JJ, Burrows SR, Gold MC, Lewinsohn DM, Sewell AK. J Immunol. 2016 Jun 15. pii: 1501402. PubMed |
| Preventing Pluripotent Cell Teratoma in Regenerative Medicine Applied to Hematology Disorders. Bedel A, Beliveau F, Lamrissi-Garcia I, Rousseau B, Moranvillier I, Rucheton B, Guyonnet-Duperat V, Cardinaud B, de Verneuil H, Moreau-Gaudry F, Dabernat S. Stem Cells Transl Med. 2016 Sep 7. pii: sctm.2016-0201. PubMed |
| Generation of transgenic marmosets expressing genetically encoded calcium indicators. Park JE, Zhang XF, Choi SH, Okahara J, Sasaki E, Silva AC. Sci Rep. 2016 Oct 11;6:34931. doi: 10.1038/srep34931. PubMed |
| Non-human Primate Schlafen11 Inhibits Production of Both Host and Viral Proteins. Stabell AC, Hawkins J, Li M, Gao X, David M, Press WH, Sawyer SL. PLoS Pathog. 2016 Dec 27;12(12):e1006066. doi: 10.1371/journal.ppat.1006066. eCollection 2016 Dec. PubMed |
| Preventing Pluripotent Cell Teratoma in Regenerative Medicine Applied to Hematology Disorders. Bedel A, Beliveau F, Lamrissi-Garcia I, Rousseau B, Moranvillier I, Rucheton B, Guyonnet-Duperat V, Cardinaud B, de Verneuil H, Moreau-Gaudry F, Dabernat S. Stem Cells Transl Med. 2017 Feb;6(2):382-393. doi: 10.5966/sctm.2016-0201. Epub 2016 Sep 7. PubMed |
| Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2. Cerda-Esteban N, Naumann H, Ruzittu S, Mah N, Pongrac IM, Cozzitorto C, Hommel A, Andrade-Navarro MA, Bonifacio E, Spagnoli FM. Nat Commun. 2017 Feb 13;8:14127. doi: 10.1038/ncomms14127. PubMed |
| Contribution of macrophages in the contrast loss in iron oxide-based MRI cancer cell tracking studies. Danhier P, Deumer G, Joudiou N, Bouzin C, Leveque P, Haufroid V, Jordan BF, Feron O, Sonveaux P, Gallez B. Oncotarget. 2017 Jun 13;8(24):38876-38885. doi: 10.18632/oncotarget.17103. PubMed |
| Shedding of host autophagic proteins from the parasitophorous vacuolar membrane of Plasmodium berghei. Agop-Nersesian C, De Niz M, Niklaus L, Prado M, Eickel N, Heussler VT. Sci Rep. 2017 May 19;7(1):2191. doi: 10.1038/s41598-017-02156-7. PubMed |
| Synchronization of excitable cardiac cultures of different origin. Agladze NN, Halaidych OV, Tsvelaya VA, Bruegmann T, Kilgus C, Sasse P, Agladze KI. Biomater Sci. 2017 Jun 23. doi: 10.1039/c7bm00171a. PubMed |
| Disruption of the C/EBPalpha-miR-182 balance impairs granulocytic differentiation. Wurm AA, Zjablovskaja P, Kardosova M, Gerloff D, Brauer-Hartmann D, Katzerke C, Hartmann JU, Benoukraf T, Fricke S, Hilger N, Muller AM, Bill M, Schwind S, Tenen DG, Niederwieser D, Alberich-Jorda M, Behre G. Nat Commun. 2017 Jun 29;8(1):46. doi: 10.1038/s41467-017-00032-6. PubMed |
| Glucocorticoids downregulate TLR4 signaling activity via its direct targeting by miR-511-5p. Curtale G, Renzi TA, Drufuca L, Rubino M, Locati M. Eur J Immunol. 2017 Dec;47(12):2080-2089. doi: 10.1002/eji.201747044. Epub 2017 Aug 31. PubMed |
| Monocarboxylate Transporter MCT1 Promotes Tumor Metastasis Independently of Its Activity as a Lactate Transporter. Payen VL, Hsu MY, Radecke KS, Wyart E, Vazeille T, Bouzin C, Porporato PE, Sonveaux P. Cancer Res. 2017 Oct 15;77(20):5591-5601. doi: 10.1158/0008-5472.CAN-17-0764. Epub 2017 Aug 21. PubMed |
| Assessment of selected media supplements to improve F/HN lentiviral vector production yields. Gelinas JF, Davies LA, Gill DR, Hyde SC. Sci Rep. 2017 Aug 31;7(1):10198. doi: 10.1038/s41598-017-07893-3. PubMed |
| Combining confocal and atomic force microscopy to quantify single-virus binding to mammalian cell surfaces. Newton R, Delguste M, Koehler M, Dumitru AC, Laskowski PR, Muller DJ, Alsteens D. Nat Protoc. 2017 Nov;12(11):2275-2292. doi: 10.1038/nprot.2017.112. Epub 2017 Oct 5. PubMed |
| Nuclear TRIM25 Specifically Targets Influenza Virus Ribonucleoproteins to Block the Onset of RNA Chain Elongation. Meyerson NR, Zhou L, Guo YR, Zhao C, Tao YJ, Krug RM, Sawyer SL. Cell Host Microbe. 2017 Nov 8;22(5):627-638.e7. doi: 10.1016/j.chom.2017.10.003. Epub 2017 Nov 5. PubMed |
| Virus stamping for targeted single-cell infection in vitro and in vivo. Schubert R, Trenholm S, Balint K, Kosche G, Cowan CS, Mohr MA, Munz M, Martinez-Martin D, Flaschner G, Newton R, Krol J, Scherf BG, Yonehara K, Wertz A, Ponti A, Ghanem A, Hillier D, Conzelmann KK, Muller DJ, Roska B. Nat Biotechnol. 2018 Jan;36(1):81-88. doi: 10.1038/nbt.4034. Epub 2017 Dec 18. PubMed |
| Differential Enzymatic Activity of Rat ADAR2 Splicing Variants Is Due to Altered Capability to Interact with RNA in the Deaminase Domain. Filippini A, Bonini D, Giacopuzzi E, La Via L, Gangemi F, Colombi M, Barbon A. Genes (Basel). 2018 Feb 8;9(2). pii: genes9020079. doi: 10.3390/genes9020079. PubMed |
| Identification of novel cell-impermeant fluorescent substrates for testing the function and drug interaction of Organic Anion-Transporting Polypeptides, OATP1B1/1B3 and 2B1. Patik I, Szekely V, Nemet O, Szepesi A, Kucsma N, Varady G, Szakacs G, Bakos E, Ozvegy-Laczka C. Sci Rep. 2018 Feb 8;8(1):2630. doi: 10.1038/s41598-018-20815-1. PubMed |
| Opposite regulation of inhibition by adult-born granule cells during implicit versus explicit olfactory learning. Mandairon N, Kuczewski N, Kermen F, Forest J, Midroit M, Richard M, Thevenet M, Sacquet J, Linster C, Didier A. Elife. 2018 Feb 28;7. pii: 34976. doi: 10.7554/eLife.34976. PubMed |
| LentiPro26: novel stable cell lines for constitutive lentiviral vector production. Tomas HA, Rodrigues AF, Carrondo MJT, Coroadinha AS. Sci Rep. 2018 Mar 27;8(1):5271. doi: 10.1038/s41598-018-23593-y. PubMed |
| HSP27 is a partner of JAK2-STAT5 and a potential therapeutic target in myelofibrosis. Sevin M, Kubovcakova L, Pernet N, Causse S, Vitte F, Villeval JL, Lacout C, Cordonnier M, Rodrigues-Lima F, Chanteloup G, Mosca M, Chretien ML, Bastie JN, Audia S, Sagot P, Ramla S, Martin L, Gleave M, Mezger V, Skoda R, Plo I, Garrido C, Girodon F, de Thonel A. Nat Commun. 2018 Apr 12;9(1):1431. doi: 10.1038/s41467-018-03627-9. PubMed |
| Neuronal network maturation differently affects secretory vesicles and mitochondria transport in axons. Moutaux E, Christaller W, Scaramuzzino C, Genoux A, Charlot B, Cazorla M, Saudou F. Sci Rep. 2018 Sep 7;8(1):13429. doi: 10.1038/s41598-018-31759-x. PubMed |
| Effect of bone marrow stromal cells in combination with biomaterials in early phases of distraction osteogenesis: An experimental study in a rabbit femur model. Montes-Medina L, Hernandez-Fernandez A, Gutierrez-Rivera A, Ripalda-Cemborain P, Bitarte N, Perez-Lopez V, Granero-Molto F, Prosper F, Izeta A. Injury. 2018 Nov;49(11):1979-1986. doi: 10.1016/j.injury.2018.09.007. Epub 2018 Sep 6. PubMed |
| Multi-Step Regulation of the TLR4 Pathway by the miR-125a~99b~let-7e Cluster. Curtale G, Renzi TA, Mirolo M, Drufuca L, Albanese M, De Luca M, Rossato M, Bazzoni F, Locati M. Front Immunol. 2018 Sep 7;9:2037. doi: 10.3389/fimmu.2018.02037. eCollection 2018. PubMed |
| An integrated microfluidic/microelectrode array for the study of activity-dependent intracellular dynamics in neuronal networks. Moutaux E, Charlot B, Genoux A, Saudou F, Cazorla M. Lab Chip. 2018 Nov 6;18(22):3425-3435. doi: 10.1039/c8lc00694f. PubMed |
| Characterization of inv(3) cell line OCI-AML-20 with stroma-dependent CD34 expression. Luciani GM, Xie L, Dilworth D, Tierens A, Moskovitz Y, Murison A, Szewczyk MM, Mitchell A, Lupien M, Shlush L, Dick JE, Arrowsmith CH, Barsyte-Lovejoy D, Minden MD. Exp Hematol. 2019 Jan;69:27-36. doi: 10.1016/j.exphem.2018.10.006. Epub 2018 Oct 22. PubMed |
| Teneurin C-Terminal Associated Peptide (TCAP)-1 and Latrophilin Interaction in HEK293 Cells: Evidence for Modulation of Intercellular Adhesion. Husic M, Barsyte-Lovejoy D, Lovejoy DA. Front Endocrinol (Lausanne). 2019 Feb 1;10:22. doi: 10.3389/fendo.2019.00022. eCollection 2019. PubMed |
| Actomyosin contractility-dependent matrix stretch and recoil induces rapid cell migration. Wang WY, Davidson CD, Lin D, Baker BM. Nat Commun. 2019 Mar 12;10(1):1186. doi: 10.1038/s41467-019-09121-0. PubMed |
| IPS-1 polymorphisms in regulating interferon response in HBV infection. Liu K, Chen L, Zhao G, Cao Z, Li F, Lin L, Zhu C, Xie Q, Xu Y, Bao S, Wang H. Biosci Trends. 2019 May 12;13(2):130-135. doi: 10.5582/bst.2018.01304. Epub 2019 Mar 29. PubMed |
| Detection and Quantification of Label-Free Infectious Adenovirus Using a Switch-On Cell-Based Fluorescent Biosensor. Guerreiro MR, Freitas DF, Alves PM, Coroadinha AS. ACS Sens. 2019 Jun 28;4(6):1654-1661. doi: 10.1021/acssensors.9b00489. Epub 2019 Jun 5. PubMed |
| Deciphering host lysosome-mediated elimination of Plasmodium berghei liver stage parasites. Niklaus L, Agop-Nersesian C, Schmuckli-Maurer J, Wacker R, Grunig V, Heussler VT. Sci Rep. 2019 May 28;9(1):7967. doi: 10.1038/s41598-019-44449-z. PubMed |
| TRIM5alpha Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation. Chiramel AI, Meyerson NR, McNally KL, Broeckel RM, Montoya VR, Mendez-Solis O, Robertson SJ, Sturdevant GL, Lubick KJ, Nair V, Youseff BH, Ireland RM, Bosio CM, Kim K, Luban J, Hirsch VM, Taylor RT, Bouamr F, Sawyer SL, Best SM. Cell Rep. 2019 Jun 11;27(11):3269-3283.e6. doi: 10.1016/j.celrep.2019.05.040. PubMed |
| Role of Adult-Born Versus Preexisting Neurons Born at P0 in Olfactory Perception in a Complex Olfactory Environment in Mice. Forest J, Chalencon L, Midroit M, Terrier C, Caille I, Sacquet J, Benetollo C, Martin K, Richard M, Didier A, Mandairon N. Cereb Cortex. 2019 Jun 19. pii: 5520592. doi: 10.1093/cercor/bhz105. PubMed |
| Mitophagy Failure in APP and Tau Overexpression Model of Alzheimer's Disease. Martin-Maestro P, Gargini R, Garcia E, Simon D, Avila J, Garcia-Escudero V. J Alzheimers Dis. 2019;70(2):525-540. doi: 10.3233/JAD-190086. PubMed |
| Synaptogenesis Stimulates a Proteasome-Mediated Ribosome Reduction in Axons. Costa RO, Martins H, Martins LF, Cwetsch AW, Mele M, Pedro JR, Tome D, Jeon NL, Cancedda L, Jaffrey SR, Almeida RD. Cell Rep. 2019 Jul 23;28(4):864-876.e6. doi: 10.1016/j.celrep.2019.06.080. PubMed |
| Regulatory mechanisms for the axonal localization of tau protein in neurons. Iwata M, Watanabe S, Yamane A, Miyasaka T, Misonou H. Mol Biol Cell. 2019 Sep 1;30(19):2441-2457. doi: 10.1091/mbc.E19-03-0183. Epub 2019 Aug 7. PubMed |
| Inhibition of Mitochondrial Complex I Impairs Release of alpha-Galactosidase by Jurkat Cells. Lambert JRA, Howe SJ, Rahim AA, Burke DG, Heales SJR. Int J Mol Sci. 2019 Sep 5;20(18). pii: ijms20184349. doi: 10.3390/ijms20184349. PubMed |
| Induced pluripotent stem cell macrophages present antigen to proinsulin-specific T cell receptors from donor-matched islet-infiltrating T cells in type 1 diabetes. Joshi K, Elso C, Motazedian A, Labonne T, Schiesser JV, Cameron F, Mannering SI, Elefanty AG, Stanley EG. Diabetologia. 2019 Dec;62(12):2245-2251. doi: 10.1007/s00125-019-04988-6. Epub 2019 Sep 12. PubMed |
| SLC1A3 contributes to L-asparaginase resistance in solid tumors. Sun J, Nagel R, Zaal EA, Ugalde AP, Han R, Proost N, Song JY, Pataskar A, Burylo A, Fu H, Poelarends GJ, van de Ven M, van Tellingen O, Berkers CR, Agami R. EMBO J. 2019 Oct 4;38(21):e102147. doi: 10.15252/embj.2019102147. Epub 2019 Sep 16. PubMed |
| Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins. Xie Y, Mansouri M, Rizk A, Berger P. Sci Rep. 2019 Sep 16;9(1):13342. doi: 10.1038/s41598-019-49646-4. PubMed |
| Improved GaLV-TR Glycoproteins to Pseudotype Lentiviral Vectors: Impact of Viral Protease Activity in the Production of LV Pseudotypes. Tomas HA, Mestre DA, Rodrigues AF, Guerreiro MR, Carrondo MJT, Coroadinha AS. Mol Ther Methods Clin Dev. 2019 Aug 14;15:1-8. doi: 10.1016/j.omtm.2019.08.001. eCollection 2019 Dec 13. PubMed |
Fate-mapping post-hypoxic tumor cells reveals a ROS-resistant phenotype that promotes metastasis.
Godet I, Shin YJ, Ju JA, Ye IC, Wang G, Gilkes DM.
Nat Commun. 2019 Oct 24;10(1):4862. doi: 10.1038/s41467-019-12412-1.
PubMed
Associated Plasmids |
| Negative Regulator of Ubiquitin-Like Protein 1 modulates the autophagy-lysosomal pathway via p62 to facilitate the extracellular release of tau following proteasome impairment. Guarascio R, Salih D, Yasvoina M, Edwards FA, Cheetham ME, van der Spuy J. Hum Mol Genet. 2020 Jan 1;29(1):80-96. doi: 10.1093/hmg/ddz255. PubMed |
| Stasimon Contributes to the Loss of Sensory Synapses and Motor Neuron Death in a Mouse Model of Spinal Muscular Atrophy. Simon CM, Van Alstyne M, Lotti F, Bianchetti E, Tisdale S, Watterson DM, Mentis GZ, Pellizzoni L. Cell Rep. 2019 Dec 17;29(12):3885-3901.e5. doi: 10.1016/j.celrep.2019.11.058. PubMed |
| Injectable, scalable 3D tissue-engineered model of marrow hematopoiesis. Tavakol DN, Tratwal J, Bonini F, Genta M, Campos V, Burch P, Hoehnel S, Beduer A, Alessandrini M, Naveiras O, Braschler T. Biomaterials. 2020 Feb;232:119665. doi: 10.1016/j.biomaterials.2019.119665. Epub 2019 Dec 11. PubMed |
| HIV-1 Reverse Transcriptase Promotes Tumor Growth and Metastasis Formation via ROS-Dependent Upregulation of Twist. Bayurova E, Jansons J, Skrastina D, Smirnova O, Mezale D, Kostyusheva A, Kostyushev D, Petkov S, Podschwadt P, Valuev-Elliston V, Sasinovich S, Korolev S, Warholm P, Latanova A, Starodubova E, Tukhvatulin A, Latyshev O, Selimov R, Metalnikov P, Komarov A, Ivanova O, Gorodnicheva T, Kochetkov S, Gottikh M, Strumfa I, Ivanov A, Gordeychuk I, Isaguliants M. Oxid Med Cell Longev. 2019 Dec 2;2019:6016278. doi: 10.1155/2019/6016278. eCollection 2019. PubMed |
| Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1. Crowther MD, Dolton G, Legut M, Caillaud ME, Lloyd A, Attaf M, Galloway SAE, Rius C, Farrell CP, Szomolay B, Ager A, Parker AL, Fuller A, Donia M, McCluskey J, Rossjohn J, Svane IM, Phillips JD, Sewell AK. Nat Immunol. 2020 Feb;21(2):178-185. doi: 10.1038/s41590-019-0578-8. Epub 2020 Jan 20. PubMed |
| Rare and private spliceosomal gene mutations drive partial, complete, and dual phenocopies of hotspot alterations. Pangallo J, Kiladjian JJ, Cassinat B, Renneville A, Taylor J, Polaski JT, North K, Abdel-Wahab O, Bradley RK. Blood. 2020 Mar 26;135(13):1032-1043. doi: 10.1182/blood.2019002894. PubMed |
| Recruitment of Host Nuclear Pore Components to the Vicinity of Theileria Schizonts. Huber S, Bar A, Epp S, Schmuckli-Maurer J, Eberhard N, Humbel BM, Hemphill A, Woods K. mSphere. 2020 Feb 5;5(1). pii: 5/1/e00709-19. doi: 10.1128/mSphere.00709-19. PubMed |
| CD229 CAR T cells eliminate multiple myeloma and tumor propagating cells without fratricide. Radhakrishnan SV, Luetkens T, Scherer SD, Davis P, Vander Mause ER, Olson ML, Yousef S, Panse J, Abdiche Y, Li KD, Miles RR, Matsui W, Welm AL, Atanackovic D. Nat Commun. 2020 Feb 7;11(1):798. doi: 10.1038/s41467-020-14619-z. PubMed |
| Reprogramming normal cells into tumour precursors requires ECM stiffness and oncogene-mediated changes of cell mechanical properties. Panciera T, Citron A, Di Biagio D, Battilana G, Gandin A, Giulitti S, Forcato M, Bicciato S, Panzetta V, Fusco S, Azzolin L, Totaro A, Dei Tos AP, Fassan M, Vindigni V, Bassetto F, Rosato A, Brusatin G, Cordenonsi M, Piccolo S. Nat Mater. 2020 Jul;19(7):797-806. doi: 10.1038/s41563-020-0615-x. Epub 2020 Feb 17. PubMed |
Accurate and live peroxisome biogenesis evaluation achieved by lentiviral expression of a green fluorescent protein fused to a peroxisome targeting signal 1.
Demaret T, Courtoy GE, Ravau J, Van Der Smissen P, Najimi M, Sokal EM.
Histochem Cell Biol. 2020 Mar 2. pii: 10.1007/s00418-020-01855-z. doi: 10.1007/s00418-020-01855-z.
PubMed
Associated Plasmids |
| TMEM87a/Elkin1, a component of a novel mechanoelectrical transduction pathway, modulates melanoma adhesion and migration. Patkunarajah A, Stear JH, Moroni M, Schroeter L, Blaszkiewicz J, Tearle JL, Cox CD, Furst C, Sanchez-Carranza O, Ocana Fernandez MDA, Fleischer R, Eravci M, Weise C, Martinac B, Biro M, Lewin GR, Poole K. Elife. 2020 Apr 1;9. pii: 53308. doi: 10.7554/eLife.53308. PubMed |
| A genetic screen identifies Crat as a regulator of pancreatic beta-cell insulin secretion. Berdous D, Berney X, Sanchez-Archidona AR, Jan M, Roujeau C, Lopez-Mejia IC, Mynatt R, Thorens B. Mol Metab. 2020 Jul;37:100993. doi: 10.1016/j.molmet.2020.100993. Epub 2020 Apr 13. PubMed |
| Intramembrane proteolysis of an extracellular serine protease, epithin/PRSS14, enables its intracellular nuclear function. Cho Y, Kim SB, Kim J, Pham AVQ, Yoon MJ, Park JH, Hwang KT, Park D, Cho Y, Kim MG, Kim C. BMC Biol. 2020 Jun 3;18(1):60. doi: 10.1186/s12915-020-00787-3. PubMed |
| Comparative analysis of lentiviral gene transfer approaches designed to promote fetal hemoglobin production for the treatment of beta-hemoglobinopathies. Daniel-Moreno A, Lamsfus-Calle A, Wilber A, Chambers CB, Johnston I, Antony JS, Epting T, Handgretinger R, Mezger M. Blood Cells Mol Dis. 2020 Sep;84:102456. doi: 10.1016/j.bcmd.2020.102456. Epub 2020 May 29. PubMed |
| Expression of the Reverse Transcriptase Domain of Telomerase Reverse Transcriptase Induces Lytic Cellular Response in DNA-Immunized Mice and Limits Tumorigenic and Metastatic Potential of Murine Adenocarcinoma 4T1 Cells. Jansons J, Bayurova E, Skrastina D, Kurlanda A, Fridrihsone I, Kostyushev D, Kostyusheva A, Artyuhov A, Dashinimaev E, Avdoshina D, Kondrashova A, Valuev-Elliston V, Latyshev O, Eliseeva O, Petkov S, Abakumov M, Hippe L, Kholodnyuk I, Starodubova E, Gorodnicheva T, Ivanov A, Gordeychuk I, Isaguliants M. Vaccines (Basel). 2020 Jun 18;8(2). pii: vaccines8020318. doi: 10.3390/vaccines8020318. PubMed |
| Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury model. Lee H, Lee HY, Lee BE, Gerovska D, Park SY, Zaehres H, Arauzo-Bravo MJ, Kim JI, Ha Y, Scholer HR, Kim JB. Elife. 2020 Jun 23;9. pii: 52069. doi: 10.7554/eLife.52069. PubMed |
| Overexpression of ER Protein Processing and Apoptosis Regulator Genes in Human Embryonic Kidney 293 Cells Improves Gene Therapy Vectors Production. Formas-Oliveira AS, Basilio JS, Rodrigues AF, Coroadinha AS. Biotechnol J. 2020 Jul 8:e1900562. doi: 10.1002/biot.201900562. PubMed |
| Nanosecond pulsed electric fields enhance mesenchymal stem cells differentiation via DNMT1-regulated OCT4/NANOG gene expression. Li K, Ning T, Wang H, Jiang Y, Zhang J, Ge Z. Stem Cell Res Ther. 2020 Jul 22;11(1):308. doi: 10.1186/s13287-020-01821-5. PubMed |
| Design and Evaluation of Guide RNA Transcripts with a 3'-Terminal HDV Ribozyme to Enhance CRISPR-Based Gene Inactivation. Berkhout B, Gao Z, Herrera-Carrillo E. Methods Mol Biol. 2021;2167:205-224. doi: 10.1007/978-1-0716-0716-9_12. PubMed |
| Design and Evaluation of AgoshRNAs with 3'-Terminal HDV Ribozymes to Enhance the Silencing Activity. Berkhout B, Herrera-Carrillo E. Methods Mol Biol. 2021;2167:225-252. doi: 10.1007/978-1-0716-0716-9_13. PubMed |
| Activation of Toll-like receptor 5 in microglia modulates their function and triggers neuronal injury. Ifuku M, Hinkelmann L, Kuhrt LD, Efe IE, Kumbol V, Buonfiglioli A, Kruger C, Jordan P, Fulde M, Noda M, Kettenmann H, Lehnardt S. Acta Neuropathol Commun. 2020 Sep 10;8(1):159. doi: 10.1186/s40478-020-01031-3. PubMed |
| Primate-restricted KRAB zinc finger proteins and target retrotransposons control gene expression in human neurons. Turelli P, Playfoot C, Grun D, Raclot C, Pontis J, Coudray A, Thorball C, Duc J, Pankevich EV, Deplancke B, Busskamp V, Trono D. Sci Adv. 2020 Aug 28;6(35):eaba3200. doi: 10.1126/sciadv.aba3200. eCollection 2020 Aug. PubMed |
| Plasmodium berghei sporozoites in nonreplicative vacuole are eliminated by a PI3P-mediated autophagy-independent pathway. Bindschedler A, Wacker R, Egli J, Eickel N, Schmuckli-Maurer J, Franke-Fayard BM, Janse CJ, Heussler VT. Cell Microbiol. 2021 Jan;23(1):e13271. doi: 10.1111/cmi.13271. Epub 2020 Oct 8. PubMed |
| Optimized Transgene Delivery Using Third-Generation Lentiviruses. Gill KP, Denham M. Curr Protoc Mol Biol. 2020 Dec;133(1):e125. doi: 10.1002/cpmb.125. PubMed |
| Tm7sf2 Disruption Alters Radial Gene Positioning in Mouse Liver Leading to Metabolic Defects and Diabetes Characteristics. Gatticchi L, de Las Heras JI, Sivakumar A, Zuleger N, Roberti R, Schirmer EC. Front Cell Dev Biol. 2020 Nov 23;8:592573. doi: 10.3389/fcell.2020.592573. eCollection 2020. PubMed |
| Evaluation of Structurally Distorted Split GFP Fluorescent Sensors for Cell-Based Detection of Viral Proteolytic Activity. Guerreiro MR, Fernandes AR, Coroadinha AS. Sensors (Basel). 2020 Dec 23;21(1). pii: s21010024. doi: 10.3390/s21010024. PubMed |
| Enhanced Expression of miR-181b in B Cells of CLL Improves the Anti-Tumor Cytotoxic T Cell Response. Di Marco M, Veschi S, Lanuti P, Ramassone A, Pacillo S, Pagotto S, Pepe F, George-William JN, Curcio C, Marchisio M, Miscia S, Innocenti I, Autore F, Vannata B, Di Gregorio P, Di Gioacchino M, Valentinuzzi S, Iezzi M, Mariani-Costantini R, Larocca LM, Laurenti L, Veronese A, Visone R. Cancers (Basel). 2021 Jan 12;13(2). pii: cancers13020257. doi: 10.3390/cancers13020257. PubMed |
| Targeted epigenetic repression by CRISPR/dSaCas9 suppresses pathogenic DUX4-fl expression in FSHD. Himeda CL, Jones TI, Jones PL. Mol Ther Methods Clin Dev. 2020 Dec 10;20:298-311. doi: 10.1016/j.omtm.2020.12.001. eCollection 2021 Mar 12. PubMed |
| Quantitative analysis of dense-core vesicle fusion in rodent CNS neurons. Moro A, Hoogstraaten RI, Persoon CM, Verhage M, Toonen RF. STAR Protoc. 2021 Feb 3;2(1):100325. doi: 10.1016/j.xpro.2021.100325. eCollection 2021 Mar 19. PubMed |
| Biofabrication of a three dimensional human-based personalized neurofibroma model. Roy V, Lamontagne R, Talagas M, Touzel-Deschenes L, Khuong HT, Saikali S, Dupre N, Gros-Louis F. Biotechnol J. 2021 Jun;16(6):e2000250. doi: 10.1002/biot.202000250. Epub 2021 Apr 7. PubMed |
| Effective, safe, and sustained correction of murine XLA using a UCOE-BTK promoter-based lentiviral vector. Seymour BJ, Singh S, Certo HM, Sommer K, Sather BD, Khim S, Clough C, Hale M, Pangallo J, Ryu BY, Khan IF, Adair JE, Rawlings DJ. Mol Ther Methods Clin Dev. 2021 Jan 20;20:635-651. doi: 10.1016/j.omtm.2021.01.007. eCollection 2021 Mar 12. PubMed |
| Single-cell transcriptome analysis of the heterogeneous effects of differential expression of tumor PD-L1 on responding TCR-T cells. Ding R, Liu S, Wang S, Chen H, Wang F, Xu Q, Zhu L, Dong X, Gu Y, Zhang X, Chao CC, Gao Q. Theranostics. 2021 Mar 5;11(10):4957-4974. doi: 10.7150/thno.55075. eCollection 2021. PubMed |
| Gain of toxic function by long-term AAV9-mediated SMN overexpression in the sensorimotor circuit. Van Alstyne M, Tattoli I, Delestree N, Recinos Y, Workman E, Shihabuddin LS, Zhang C, Mentis GZ, Pellizzoni L. Nat Neurosci. 2021 Jul;24(7):930-940. doi: 10.1038/s41593-021-00827-3. Epub 2021 Apr 1. PubMed |
| A nonviral, nonintegrating DNA nanovector platform for the safe, rapid, and persistent manufacture of recombinant T cells. Bozza M, De Roia A, Correia MP, Berger A, Tuch A, Schmidt A, Zornig I, Jager D, Schmidt P, Harbottle RP. Sci Adv. 2021 Apr 14;7(16). pii: 7/16/eabf1333. doi: 10.1126/sciadv.abf1333. Print 2021 Apr. PubMed |
| Apical CLC-2 in retinal pigment epithelium is crucial for survival of the outer retina. Hanke-Gogokhia C, Lehmann GL, Benedicto I, de la Fuente-Ortega E, Arshavsky VY, Schreiner R, Rodriguez-Boulan E. FASEB J. 2021 Jul;35(7):e21689. doi: 10.1096/fj.202100349R. PubMed |
| Galphaq activation modulates autophagy by promoting mTORC1 signaling. Cabezudo S, Sanz-Flores M, Caballero A, Tasset I, Rebollo E, Diaz A, Aragay AM, Cuervo AM, Mayor F Jr, Ribas C. Nat Commun. 2021 Jul 27;12(1):4540. doi: 10.1038/s41467-021-24811-4. PubMed |
| Sumoylation regulates the assembly and activity of the SMN complex. Riboldi GM, Faravelli I, Kuwajima T, Delestree N, Dermentzaki G, De Planell-Saguer M, Rinchetti P, Hao LT, Beattie CC, Corti S, Przedborski S, Mentis GZ, Lotti F. Nat Commun. 2021 Aug 19;12(1):5040. doi: 10.1038/s41467-021-25272-5. PubMed |
| Circumventricular Organ Apelin Receptor Knockdown Decreases Blood Pressure and Sympathetic Drive Responses in the Spontaneously Hypertensive Rat. Griffiths PR, Lolait SJ, Paton JFR, O'Carroll AM. Front Physiol. 2021 Aug 4;12:711041. doi: 10.3389/fphys.2021.711041. eCollection 2021. PubMed |
| miR-9-5p is involved in the rescue of stress-dependent dendritic shortening of hippocampal pyramidal neurons induced by acute antidepressant treatment with ketamine. Mingardi J, La Via L, Tornese P, Carini G, Trontti K, Seguini M, Tardito D, Bono F, Fiorentini C, Elia L, Hovatta I, Popoli M, Musazzi L, Barbon A. Neurobiol Stress. 2021 Aug 12;15:100381. doi: 10.1016/j.ynstr.2021.100381. eCollection 2021 Nov. PubMed |
Discovery of synthetic lethal and tumor suppressor paralog pairs in the human genome.
Parrish PCR, Thomas JD, Gabel AM, Kamlapurkar S, Bradley RK, Berger AH.
Cell Rep. 2021 Aug 31;36(9):109597. doi: 10.1016/j.celrep.2021.109597.
PubMed
Associated Plasmids |
| Human cytomegalovirus expands a CD8(+) T cell population with loss of BCL11B expression and gain of NK cell identity. Sottile R, Panjwani MK, Lau CM, Daniyan AF, Tanaka K, Barker JN, Brentjens RJ, Sun JC, Le Luduec JB, Hsu KC. Sci Immunol. 2021 Sep 24;6(63):eabe6968. doi: 10.1126/sciimmunol.abe6968. Epub 2021 Sep 24. PubMed |
| A persistent invasive phenotype in post-hypoxic tumor cells is revealed by fate mapping and computational modeling. Rocha HL, Godet I, Kurtoglu F, Metzcar J, Konstantinopoulos K, Bhoyar S, Gilkes DM, Macklin P. iScience. 2021 Aug 4;24(9):102935. doi: 10.1016/j.isci.2021.102935. eCollection 2021 Sep 24. PubMed |
| Cooperative methylation of human tRNA3Lys at positions A58 and U54 drives the early and late steps of HIV-1 replication. Fukuda H, Chujo T, Wei FY, Shi SL, Hirayama M, Kaitsuka T, Yamamoto T, Oshiumi H, Tomizawa K. Nucleic Acids Res. 2021 Nov 18;49(20):11855-11867. doi: 10.1093/nar/gkab879. PubMed |
| Time-Resolved Scanning Ion Conductance Microscopy for Three-Dimensional Tracking of Nanoscale Cell Surface Dynamics. Leitao SM, Drake B, Pinjusic K, Pierrat X, Navikas V, Nievergelt AP, Brillard C, Djekic D, Radenovic A, Persat A, Constam DB, Anders J, Fantner GE. ACS Nano. 2021 Nov 9. doi: 10.1021/acsnano.1c05202. PubMed |
| Cancer-cell-derived GABA promotes beta-catenin-mediated tumour growth and immunosuppression. Huang D, Wang Y, Thompson JW, Yin T, Alexander PB, Qin D, Mudgal P, Wu H, Liang Y, Tan L, Pan C, Yuan L, Wan Y, Li QJ, Wang XF. Nat Cell Biol. 2022 Feb;24(2):230-241. doi: 10.1038/s41556-021-00820-9. Epub 2022 Feb 10. PubMed |
| Synthetic introns enable splicing factor mutation-dependent targeting of cancer cells. North K, Benbarche S, Liu B, Pangallo J, Chen S, Stahl M, Bewersdorf JP, Stanley RF, Erickson C, Cho H, Pineda JMB, Thomas JD, Polaski JT, Belleville AE, Gabel AM, Udy DB, Humbert O, Kiem HP, Abdel-Wahab O, Bradley RK. Nat Biotechnol. 2022 Jul;40(7):1103-1113. doi: 10.1038/s41587-022-01224-2. Epub 2022 Mar 3. PubMed |
| PRMT5 regulates ATF4 transcript splicing and oxidative stress response. Szewczyk MM, Luciani GM, Vu V, Murison A, Dilworth D, Barghout SH, Lupien M, Arrowsmith CH, Minden MD, Barsyte-Lovejoy D. Redox Biol. 2022 May;51:102282. doi: 10.1016/j.redox.2022.102282. Epub 2022 Mar 11. PubMed |
| 12 months is a pivotal age for olfactory perceptual learning and its underlying neuronal plasticity in aging mice. Greco-Vuilloud J, Midroit M, Terrier C, Forest J, Sacquet J, Mandairon N, Didier A, Richard M. Neurobiol Aging. 2022 Jun;114:73-83. doi: 10.1016/j.neurobiolaging.2022.03.003. Epub 2022 Mar 9. PubMed |
| Low-affinity CAR T cells exhibit reduced trogocytosis, preventing rapid antigen loss, and increasing CAR T cell expansion. Olson ML, Mause ERV, Radhakrishnan SV, Brody JD, Rapoport AP, Welm AL, Atanackovic D, Luetkens T. Leukemia. 2022 Jul;36(7):1943-1946. doi: 10.1038/s41375-022-01585-2. Epub 2022 Apr 30. PubMed |
| SMN controls neuromuscular junction integrity through U7 snRNP. Tisdale S, Van Alstyne M, Simon CM, Mentis GZ, Pellizzoni L. Cell Rep. 2022 Sep 20;40(12):111393. doi: 10.1016/j.celrep.2022.111393. PubMed |
| Contrasting effects of Ksr2, an obesity gene, on trabecular bone volume and bone marrow adiposity. Gomez GA, Rundle CH, Xing W, Kesavan C, Pourteymoor S, Lewis RE, Powell DR, Mohan S. Elife. 2022 Nov 7;11:e82810. doi: 10.7554/eLife.82810. PubMed |
| Tissue-Resident Memory T Cells in Pancreatic Ductal Adenocarcinoma Coexpress PD-1 and TIGIT and Functional Inhibition Is Reversible by Dual Antibody Blockade. Pearce H, Croft W, Nicol SM, Margielewska-Davies S, Powell R, Cornall R, Davis SJ, Marcon F, Pugh MR, Fennell E, Powell-Brett S, Mahon BS, Brown RM, Middleton G, Roberts K, Moss P. Cancer Immunol Res. 2023 Apr 3;11(4):435-449. doi: 10.1158/2326-6066.CIR-22-0121. PubMed |
| Environmental signals perceived by the brain abate pro-metastatic monocytes by dampening glucocorticoids receptor signaling. Canali MM, Guyot M, Simon T, Daoudlarian D, Chabry J, Panzolini C, Petit-Paitel A, Hypolite N, Nicolas S, Bourdely P, Schmid-Antomarchi H, Schmid-Alliana A, Soria J, Karimdjee Soilihi B, Hofman P, Prevost-Blondel A, Kato M, Mougneau E, Glaichenhaus N, Blancou P. Cancer Cell Int. 2023 Feb 1;23(1):15. doi: 10.1186/s12935-023-02855-4. PubMed |
| Human EGFRvIII chimeric antigen receptor T cells demonstrate favorable safety profile and curative responses in orthotopic glioblastoma. Abbott RC, Iliopoulos M, Watson KA, Arcucci V, Go M, Hughes-Parry HE, Smith P, Call MJ, Cross RS, Jenkins MR. Clin Transl Immunology. 2023 Mar 5;12(3):e1440. doi: 10.1002/cti2.1440. eCollection 2023. PubMed |
| PTPN22 R620W gene editing in T cells enhances low-avidity TCR responses. Anderson W, Barahmand-Pour-Whitman F, Linsley PS, Cerosaletti K, Buckner JH, Rawlings DJ. Elife. 2023 Mar 24;12:e81577. doi: 10.7554/eLife.81577. PubMed |
| Murine macrophage-based iNos reporter reveals polarization and reprogramming in the context of breast cancer. Mas-Rosario JA, Medor JD, Jeffway MI, Martinez-Montes JM, Farkas ME. Front Oncol. 2023 Apr 5;13:1151384. doi: 10.3389/fonc.2023.1151384. eCollection 2023. PubMed |
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