pLKO.1 puro Citations (236)

Plasmid Article: Lentivirus-delivered stable gene silencing by RNAi in primary cells.
Stewart SA, Dykxhoorn DM, Palliser D, Mizuno H, Yu EY, An DS, Sabatini DM, Chen IS, Hahn WC, Sharp PA, Weinberg RA, Novina CD RNA 2003 Apr;9(4):493-501. PubMed Journal

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Articles Citing pLKO.1 puro

Articles
PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding. Wang L, Harris TE, Roth RA, Lawrence JC. J Biol Chem. 2007 Jul 6. 282(27):20036-44. PubMed Associated Plasmids PRAS40 (mouse) shRNA HA PRAS40 F129A HA PRAS40 S183A HA PRAS40 P185A
Raptor binds the SAIN (Shc and IRS-1 NPXY binding) domain of insulin receptor substrate-1 (IRS-1) and regulates the phosphorylation of IRS-1 at Ser-636/639 by mTOR. Tzatsos A. J Biol Chem. 2009 Aug 21;284(34):22525-34. doi: 10.1074/jbc.M109.027748. Epub 2009 Jun 26. PubMed
Identification of prospective factors promoting osteotropism in breast cancer: a potential role for CITED2. Lau WM, Weber KL, Doucet M, Chou YT, Brady K, Kowalski J, Tsai HL, Yang J, Kominsky SL. Int J Cancer. 2010 Feb 15;126(4):876-84. doi: 10.1002/ijc.24780. PubMed
Phagocytosis of cells dying through autophagy induces inflammasome activation and IL-1beta release in human macrophages. Petrovski G, Ayna G, Majai G, Hodrea J, Benko S, Madi A, Fesus L. Autophagy. 2011 Mar;7(3):321-30. PubMed
Scavenger receptor WC1 contributes to the gammadelta T cell response to Leptospira. Wang F, Herzig CT, Chen C, Hsu H, Baldwin CL, Telfer JC. Mol Immunol. 2011 Mar;48(6-7):801-9. doi: 10.1016/j.molimm.2010.12.001. Epub 2011 Jan 11. PubMed
JNK signaling promotes intestinal tumorigenesis through activation of mTOR complex 1 in Apc(Delta716) mice. Fujishita T, Aoki M, Taketo MM. Gastroenterology. 2011 May;140(5):1556-63.e6. doi: 10.1053/j.gastro.2011.02.007. Epub 2011 Feb 12. PubMed
Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development. Kawazu M, Saso K, Tong KI, McQuire T, Goto K, Son DO, Wakeham A, Miyagishi M, Mak TW, Okada H. PLoS One. 2011 Mar 18;6(3):e17830. doi: 10.1371/journal.pone.0017830. PubMed
The function of hypoxia-inducible factor (HIF) is independent of the endoplasmic reticulum protein OS-9. Brockmeier U, Platzek C, Schneider K, Patak P, Bernardini A, Fandrey J, Metzen E. PLoS One. 2011 Apr 29;6(4):e19151. doi: 10.1371/journal.pone.0019151. PubMed
Willin/FRMD6 expression activates the Hippo signaling pathway kinases in mammals and antagonizes oncogenic YAP. Angus L, Moleirinho S, Herron L, Sinha A, Zhang X, Niestrata M, Dholakia K, Prystowsky MB, Harvey KF, Reynolds PA, Gunn-Moore FJ. Oncogene. 2012 Jan 12;31(2):238-50. doi: 10.1038/onc.2011.224. Epub 2011 Jun 13. PubMed Associated Plasmids pBabepuro-Willin pLKO.1puro-shWillin-A pLKO.1puro-shWillin-B
Loss of DLK expression in WI-38 human diploid fibroblasts induces a senescent-like proliferation arrest. Daviau A, Couture JP, Blouin R. Biochem Biophys Res Commun. 2011 Sep 23;413(2):282-7. doi: 10.1016/j.bbrc.2011.08.086. Epub 2011 Aug 27. PubMed
Inhibition of the Notch-Hey1 axis blocks embryonal rhabdomyosarcoma tumorigenesis. Belyea BC, Naini S, Bentley RC, Linardic CM. Clin Cancer Res. 2011 Dec 1;17(23):7324-36. doi: 10.1158/1078-0432.CCR-11-1004. Epub 2011 Sep 23. PubMed
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells. Cordenonsi M, Zanconato F, Azzolin L, Forcato M, Rosato A, Frasson C, Inui M, Montagner M, Parenti AR, Poletti A, Daidone MG, Dupont S, Basso G, Bicciato S, Piccolo S. Cell. 2011 Nov 11;147(4):759-72. doi: 10.1016/j.cell.2011.09.048. PubMed
FGF signalling inhibits neural induction in human embryonic stem cells. Greber B, Coulon P, Zhang M, Moritz S, Frank S, Muller-Molina AJ, Arauzo-Bravo MJ, Han DW, Pape HC, Scholer HR. EMBO J. 2011 Nov 15;30(24):4874-84. doi: 10.1038/emboj.2011.407. PubMed
Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms. Piskounova E, Polytarchou C, Thornton JE, LaPierre RJ, Pothoulakis C, Hagan JP, Iliopoulos D, Gregory RI. Cell. 2011 Nov 23;147(5):1066-79. doi: 10.1016/j.cell.2011.10.039. PubMed
gamma-Tubulin 2 nucleates microtubules and is downregulated in mouse early embryogenesis. Vinopal S, Cernohorska M, Sulimenko V, Sulimenko T, Vosecka V, Flemr M, Draberova E, Draber P. PLoS One. 2012;7(1):e29919. doi: 10.1371/journal.pone.0029919. Epub 2012 Jan 3. PubMed
The cyclin-like protein Spy1/RINGO promotes mammary transformation and is elevated in human breast cancer. Al Sorkhy M, Ferraiuolo RM, Jalili E, Malysa A, Fratiloiu AR, Sloane BF, Porter LA. BMC Cancer. 2012 Jan 26;12:45. doi: 10.1186/1471-2407-12-45. PubMed
Combining competition assays with genetic complementation strategies to dissect mouse embryonic stem cell self-renewal and pluripotency. Lee DF, Su J, Sevilla A, Gingold J, Schaniel C, Lemischka IR. Nat Protoc. 2012 Mar 22;7(4):729-48. doi: 10.1038/nprot.2012.018. PubMed
KIBRA exhibits MST-independent functional regulation of the Hippo signaling pathway in mammals. Moleirinho S, Chang N, Sims AH, Tilston-Lunel AM, Angus L, Steele A, Boswell V, Barnett SC, Ormandy C, Faratian D, Gunn-Moore FJ, Reynolds PA. Oncogene. 2012 May 21. doi: 10.1038/onc.2012.196. PubMed Associated Plasmids pBabepuro-KIBRA pLKO.1puro-shKIBRA-A pLKO.1puro-shKIBRA-B
FGFR4 blockade exerts distinct antitumorigenic effects in human embryonal versus alveolar rhabdomyosarcoma. Crose LE, Etheridge KT, Chen C, Belyea B, Talbot LJ, Bentley RC, Linardic CM. Clin Cancer Res. 2012 Jul 15;18(14):3780-90. doi: 10.1158/1078-0432.CCR-10-3063. Epub 2012 May 30. PubMed
Inverted Alu dsRNA structures do not affect localization but can alter translation efficiency of human mRNAs independent of RNA editing. Capshew CR, Dusenbury KL, Hundley HA. Nucleic Acids Res. 2012 Sep 1;40(17):8637-45. Epub 2012 Jun 25. PubMed
New insight into the SDF-1/CXCR4 axis in a breast carcinoma model: hypoxia-induced endothelial SDF-1 and tumor cell CXCR4 are required for tumor cell intravasation. Jin F, Brockmeier U, Otterbach F, Metzen E. Mol Cancer Res. 2012 Aug;10(8):1021-31. doi: 10.1158/1541-7786.MCR-11-0498. Epub 2012 Jul 5. PubMed
The oncogene LRF is a survival factor in chondrosarcoma and contributes to tumor malignancy and drug resistance. Kumari R, Li H, Haudenschild DR, Fierro F, Carlson CS, Overn P, Gupta L, Gupta K, Nolta J, Yik JH, Di Cesare PE. Carcinogenesis. 2012 Nov;33(11):2076-83. doi: 10.1093/carcin/bgs254. Epub 2012 Jul 30. PubMed
High-mobility group box 2 (HMGB2) modulates radioresponse and is downregulated by p53 in colorectal cancer cell. Shin YJ, Kim MS, Kim MS, Lee J, Kang M, Jeong JH. Cancer Biol Ther. 2013 Mar;14(3):213-21. doi: 10.4161/cbt.23292. Epub 2012 Dec 19. PubMed
Gene transduction in human monocyte-derived dendritic cells using lentiviral vectors. Satoh T, Manel N. Methods Mol Biol. 2013;960:401-9. doi: 10.1007/978-1-62703-218-6_30. PubMed
alpha-SNAP inhibits AMPK signaling to reduce mitochondrial biogenesis and dephosphorylates Thr172 in AMPKalpha in vitro. Wang L, Brautigan DL. Nat Commun. 2013;4:1559. doi: 10.1038/ncomms2565. PubMed
Mammalian target of rapamycin (mTor) mediates tau protein dyshomeostasis: implication for Alzheimer disease. Tang Z, Bereczki E, Zhang H, Wang S, Li C, Ji X, Branca RM, Lehtio J, Guan Z, Filipcik P, Xu S, Winblad B, Pei JJ. J Biol Chem. 2013 May 31;288(22):15556-70. doi: 10.1074/jbc.M112.435123. Epub 2013 Apr 12. PubMed
Cadherin-17 interacts with alpha2beta1 integrin to regulate cell proliferation and adhesion in colorectal cancer cells causing liver metastasis. Bartolome RA, Barderas R, Torres S, Fernandez-Acenero MJ, Mendes M, Garcia-Foncillas J, Lopez-Lucendo M, Casal JI. Oncogene. 2014 Mar 27;33(13):1658-69. doi: 10.1038/onc.2013.117. Epub 2013 Apr 22. PubMed
Factor inhibiting HIF-1 (FIH-1) modulates protein interactions of apoptosis-stimulating p53 binding protein 2 (ASPP2). Janke K, Brockmeier U, Kuhlmann K, Eisenacher M, Nolde J, Meyer HE, Mairbaurl H, Metzen E. J Cell Sci. 2013 Jun 15;126(Pt 12):2629-40. doi: 10.1242/jcs.117564. Epub 2013 Apr 19. PubMed
Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia. Willems L, Jacque N, Jacquel A, Neveux N, Maciel TT, Lambert M, Schmitt A, Poulain L, Green AS, Uzunov M, Kosmider O, Radford-Weiss I, Moura IC, Auberger P, Ifrah N, Bardet V, Chapuis N, Lacombe C, Mayeux P, Tamburini J, Bouscary D. Blood. 2013 Nov 14;122(20):3521-32. doi: 10.1182/blood-2013-03-493163. Epub 2013 Sep 6. PubMed
miR-26a enhances miRNA biogenesis by targeting Lin28B and Zcchc11 to suppress tumor growth and metastasis. Fu X, Meng Z, Liang W, Tian Y, Wang X, Han W, Lou G, Wang X, Lou F, Yen Y, Yu H, Jove R, Huang W. Oncogene. 2014 Aug 21;33(34):4296-306. doi: 10.1038/onc.2013.385. Epub 2013 Sep 23. PubMed
Ephrin-A1 expression induced by S100A8 is mediated by the toll-like receptor 4. Ieguchi K, Omori T, Komatsu A, Tomita T, Deguchi A, Maru Y. Biochem Biophys Res Commun. 2013 Nov 1;440(4):623-9. doi: 10.1016/j.bbrc.2013.09.119. Epub 2013 Oct 5. PubMed
Lentiviral overexpression of miRNAs. Zollner H, Hahn SA, Maghnouj A. Methods Mol Biol. 2014;1095:177-90. doi: 10.1007/978-1-62703-703-7_15. PubMed
PRDM14 promotes active DNA demethylation through the ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells. Okashita N, Kumaki Y, Ebi K, Nishi M, Okamoto Y, Nakayama M, Hashimoto S, Nakamura T, Sugasawa K, Kojima N, Takada T, Okano M, Seki Y. Development. 2014 Jan;141(2):269-80. doi: 10.1242/dev.099622. Epub 2013 Dec 11. PubMed
microRNAs miR-27a and miR-27b directly regulate liver dihydropyrimidine dehydrogenase expression through two conserved binding sites. Offer SM, Butterfield GL, Jerde CR, Fossum CC, Wegner NJ, Diasio RB. Mol Cancer Ther. 2014 Mar;13(3):742-51. doi: 10.1158/1535-7163.MCT-13-0878. Epub 2014 Jan 8. PubMed
Plakoglobin but not desmoplakin regulates keratinocyte cohesion via modulation of p38MAPK signaling. Spindler V, Dehner C, Hubner S, Waschke J. J Invest Dermatol. 2014 Jun;134(6):1655-64. doi: 10.1038/jid.2014.21. Epub 2014 Jan 17. PubMed
Cyclin-dependent kinase 9 inhibition protects cartilage from the catabolic effects of proinflammatory cytokines. Yik JH, Hu Z, Kumari R, Christiansen BA, Haudenschild DR. Arthritis Rheumatol. 2014 Jun;66(6):1537-46. doi: 10.1002/art.38378. PubMed
Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos. Niu Y, Shen B, Cui Y, Chen Y, Wang J, Wang L, Kang Y, Zhao X, Si W, Li W, Xiang AP, Zhou J, Guo X, Bi Y, Si C, Hu B, Dong G, Wang H, Zhou Z, Li T, Tan T, Pu X, Wang F, Ji S, Zhou Q, Huang X, Ji W, Sha J. Cell. 2014 Feb 13;156(4):836-43. doi: 10.1016/j.cell.2014.01.027. Epub 2014 Jan 30. PubMed
Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects. Shen B, Zhang W, Zhang J, Zhou J, Wang J, Chen L, Wang L, Hodgkins A, Iyer V, Huang X, Skarnes WC. Nat Methods. 2014 Mar 2. doi: 10.1038/nmeth.2857. PubMed Associated Plasmids pST1374-N-NLS-flag-linker-Cas9-H840A pST1374-N-NLS-flag-linker-Cas9-D10A pUC57-sgRNA expression vector pGL3-U6-sgRNA-PGK-puromycin
hCLE/C14orf166 associates with DDX1-HSPC117-FAM98B in a novel transcription-dependent shuttling RNA-transporting complex. Perez-Gonzalez A, Pazo A, Navajas R, Ciordia S, Rodriguez-Frandsen A, Nieto A. PLoS One. 2014 Mar 7;9(3):e90957. doi: 10.1371/journal.pone.0090957. eCollection 2014. PubMed
Anoctamin 6 regulates C2C12 myoblast proliferation. Zhao P, Torcaso A, Mariano A, Xu L, Mohsin S, Zhao L, Han R. PLoS One. 2014 Mar 24;9(3):e92749. doi: 10.1371/journal.pone.0092749. eCollection 2014. PubMed Associated Plasmids ANO6-Plvx-mCherry-c1
ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism. Yang Y, Ahn YH, Chen Y, Tan X, Guo L, Gibbons DL, Ungewiss C, Peng DH, Liu X, Lin SH, Thilaganathan N, Wistuba II, Rodriguez-Canales J, McLendon G, Creighton CJ, Kurie JM. J Clin Invest. 2014 Jun;124(6):2696-708. doi: 10.1172/JCI72171. Epub 2014 Apr 24. PubMed
MS4A8B promotes cell proliferation in prostate cancer. Ye L, Yao XD, Wan FN, Qu YY, Liu ZY, Shen XX, Li S, Liu XJ, Yue F, Wang N, Dai B, Ye DW. Prostate. 2014 Jun;74(9):911-22. doi: 10.1002/pros.22802. Epub 2014 Apr 30. PubMed
Murine norovirus: propagation, quantification, and genetic manipulation. Hwang S, Alhatlani B, Arias A, Caddy SL, Christodoulou C, Cunha JB, Emmott E, Gonzalez-Hernandez M, Kolawole A, Lu J, Rippinger C, Sorgeloos F, Thorne L, Vashist S, Goodfellow I, Wobus CE. Curr Protoc Microbiol. 2014 May 1;33:15K.2.1-61. doi: 10.1002/9780471729259.mc15k02s33. PubMed
SOX2 is a cancer-specific regulator of tumour initiating potential in cutaneous squamous cell carcinoma. Siegle JM, Basin A, Sastre-Perona A, Yonekubo Y, Brown J, Sennett R, Rendl M, Tsirigos A, Carucci JA, Schober M. Nat Commun. 2014 Jul 31;5:4511. doi: 10.1038/ncomms5511. PubMed
Goat activin receptor type IIB knockdown by muscle specific promoter driven artificial microRNAs. Patel AK, Shah RK, Patel UA, Tripathi AK, Joshi CG. J Biotechnol. 2014 Oct 10;187:87-97. doi: 10.1016/j.jbiotec.2014.07.450. Epub 2014 Aug 7. PubMed
Regulation of mitochondrial function and cellular energy metabolism by protein kinase C-lambda/iota: a novel mode of balancing pluripotency. Mahato B, Home P, Rajendran G, Paul A, Saha B, Ganguly A, Ray S, Roy N, Swerdlow RH, Paul S. Stem Cells. 2014 Nov;32(11):2880-92. doi: 10.1002/stem.1817. PubMed
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells. Plotnik JP, Budka JA, Ferris MW, Hollenhorst PC. Nucleic Acids Res. 2014 Oct 29;42(19):11928-40. doi: 10.1093/nar/gku929. Epub 2014 Oct 7. PubMed
An optical labeling-based proliferation assay system reveals the paracrine effect of interleukin-6 in breast cancer. Itou J, Tanaka S, Sato F, Akiyama R, Kawakami Y, Toi M. Biochim Biophys Acta. 2015 Jan;1853(1):27-40. doi: 10.1016/j.bbamcr.2014.10.004. Epub 2014 Oct 12. PubMed
JNK-NQO1 axis drives TAp73-mediated tumor suppression upon oxidative and proteasomal stress. Kostecka A, Sznarkowska A, Meller K, Acedo P, Shi Y, Mohammad Sakil HA, Kawiak A, Lion M, Krolicka A, Wilhelm M, Inga A, Zawacka-Pankau J. Cell Death Dis. 2014 Oct 23;5:e1484. doi: 10.1038/cddis.2014.408. PubMed
MicroRNA-29c/PTEN pathway is involved in mice brain development and modulates neurite outgrowth in PC12 cells. Zou H, Ding Y, Shi W, Xu X, Gong A, Zhang Z, Liu J. Cell Mol Neurobiol. 2015 Apr;35(3):313-22. doi: 10.1007/s10571-014-0126-x. Epub 2014 Oct 29. PubMed
Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD. Mitter SK, Song C, Qi X, Mao H, Rao H, Akin D, Lewin A, Grant M, Dunn W Jr, Ding J, Bowes Rickman C, Boulton M. Autophagy. 2014;10(11):1989-2005. doi: 10.4161/auto.36184. PubMed
YAP-mediated induction of monoacylglycerol lipase restrains oncogenic transformation. Tang ED, Wang CY. Cell Signal. 2015 Apr;27(4):836-40. doi: 10.1016/j.cellsig.2015.01.011. Epub 2015 Jan 28. PubMed
GADS is required for TCR-mediated calcium influx and cytokine release, but not cellular adhesion, in human T cells. Bilal MY, Zhang EY, Dinkel B, Hardy D, Yankee TM, Houtman JC. Cell Signal. 2015 Apr;27(4):841-50. doi: 10.1016/j.cellsig.2015.01.012. Epub 2015 Jan 28. PubMed
EWI-2 negatively regulates TGF-beta signaling leading to altered melanoma growth and metastasis. Wang HX, Sharma C, Knoblich K, Granter SR, Hemler ME. Cell Res. 2015 Mar;25(3):370-85. doi: 10.1038/cr.2015.17. Epub 2015 Feb 6. PubMed
MicroRNA-29A/PTEN pathway modulates neurite outgrowth in PC12 cells. Zou H, Ding Y, Wang K, Xiong E, Peng W, Du F, Zhang Z, Liu J, Gong A. Neuroscience. 2015 Apr 16;291:289-300. doi: 10.1016/j.neuroscience.2015.01.055. Epub 2015 Feb 7. PubMed
miR-191 promotes tumorigenesis of human colorectal cancer through targeting C/EBPbeta. Zhang XF, Li KK, Gao L, Li SZ, Chen K, Zhang JB, Wang D, Tu RF, Zhang JX, Tao KX, Wang G, Zhang XD. Oncotarget. 2015 Feb 28;6(6):4144-58. PubMed
GRB2 Nucleates T Cell Receptor-Mediated LAT Clusters That Control PLC-gamma1 Activation and Cytokine Production. Bilal MY, Houtman JC. Front Immunol. 2015 Mar 30;6:141. doi: 10.3389/fimmu.2015.00141. eCollection 2015. PubMed
Leukemia stem cells in T-ALL require active Hif1alpha and Wnt signaling. Giambra V, Jenkins CE, Lam SH, Hoofd C, Belmonte M, Wang X, Gusscott S, Gracias D, Weng AP. Blood. 2015 Jun 18;125(25):3917-27. doi: 10.1182/blood-2014-10-609370. Epub 2015 May 1. PubMed
Co-activation of AMPK and mTORC1 Induces Cytotoxicity in Acute Myeloid Leukemia. Sujobert P, Poulain L, Paubelle E, Zylbersztejn F, Grenier A, Lambert M, Townsend EC, Brusq JM, Nicodeme E, Decrooqc J, Nepstad I, Green AS, Mondesir J, Hospital MA, Jacque N, Christodoulou A, Desouza TA, Hermine O, Foretz M, Viollet B, Lacombe C, Mayeux P, Weinstock DM, Moura IC, Bouscary D, Tamburini J. Cell Rep. 2015 Jun 9;11(9):1446-57. doi: 10.1016/j.celrep.2015.04.063. Epub 2015 May 21. PubMed
Optimization of methods for the genetic modification of human T cells. Bilal MY, Vacaflores A, Houtman JC. Immunol Cell Biol. 2015 Nov;93(10):896-908. doi: 10.1038/icb.2015.59. Epub 2015 Jun 1. PubMed
Secreted Frizzled-Related Protein 3 (SFRP3) Is Required for Tumorigenesis of PAX3-FOXO1-Positive Alveolar Rhabdomyosarcoma. Kephart JJ, Tiller RG, Crose LE, Slemmons KK, Chen PH, Hinson AR, Bentley RC, Chi JT, Linardic CM. Clin Cancer Res. 2015 Nov 1;21(21):4868-80. doi: 10.1158/1078-0432.CCR-14-1797. Epub 2015 Jun 12. PubMed
Critical role of Wnt/beta-catenin signaling in driving epithelial ovarian cancer platinum resistance. Nagaraj AB, Joseph P, Kovalenko O, Singh S, Armstrong A, Redline R, Resnick K, Zanotti K, Waggoner S, DiFeo A. Oncotarget. 2015 Sep 15;6(27):23720-34. PubMed
Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition. Jacque N, Ronchetti AM, Larrue C, Meunier G, Birsen R, Willems L, Saland E, Decroocq J, Thiago TT, Lambert M, Poulain L, Hospital MA, Sujobert P, Joseph L, Chapuis N, Lacombe C, Moura IC, Demo S, Sarry JE, Recher C, Mayeux P, Tamburini J, Bouscary D. Blood. 2015 Sep 10;126(11):1346-56. doi: 10.1182/blood-2015-01-621870. Epub 2015 Jul 17. PubMed
The Glycogen Synthase Kinase 3alpha and beta Isoforms Differentially Regulates Interleukin-12p40 Expression in Endothelial Cells Stimulated with Peptidoglycan from Staphylococcus aureus. Cortes-Vieyra R, Silva-Garcia O, Oviedo-Boyso J, Huante-Mendoza A, Bravo-Patino A, Valdez-Alarcon JJ, Finlay BB, Baizabal-Aguirre VM. PLoS One. 2015 Jul 22;10(7):e0132867. doi: 10.1371/journal.pone.0132867. eCollection 2015. PubMed
Myosin 1b Regulates Amino Acid Transport by Associating Transporters with the Apical Plasma Membrane of Kidney Cells. Komaba S, Coluccio LM. PLoS One. 2015 Sep 11;10(9):e0138012. doi: 10.1371/journal.pone.0138012. eCollection 2015. PubMed
LDL suppresses angiogenesis through disruption of the HIF pathway via NF-kappaB inhibition which is reversed by the proteasome inhibitor BSc2118. Yao G, Zhang Q, Doeppner TR, Niu F, Li Q, Yang Y, Kuckelkorn U, Hagemann N, Li W, Hermann DM, Dai Y, Zhou W, Jin F. Oncotarget. 2015 Oct 6;6(30):30251-62. doi: 10.18632/oncotarget.4943. PubMed
Paclitaxel-induced transcriptional regulation of Fas signaling pathway is antagonized by dexamethasone. Crozier M, Porter LA. Breast Cancer Res Treat. 2015 Nov;154(1):33-44. PubMed
Transcription factor CREB3L1 mediates cAMP and glucocorticoid regulation of arginine vasopressin gene transcription in the rat hypothalamus. Greenwood M, Greenwood MP, Mecawi AS, Loh SY, Rodrigues JA, Paton JF, Murphy D. Mol Brain. 2015 Oct 26;8(1):68. doi: 10.1186/s13041-015-0159-1. PubMed
Transcriptional regulation of APOBEC3 antiviral immunity through the CBF-beta/RUNX axis. Anderson BD, Harris RS. Sci Adv. 2015 Sep 18;1(8):e1500296. doi: 10.1126/sciadv.1500296. eCollection 2015 Sep. PubMed
Human Umbilical Tissue-Derived Cells Promote Synapse Formation and Neurite Outgrowth via Thrombospondin Family Proteins. Koh S, Kim N, Yin HH, Harris IR, Dejneka NS, Eroglu C. J Neurosci. 2015 Nov 25;35(47):15649-65. doi: 10.1523/JNEUROSCI.1364-15.2015. PubMed
Rasd1, a small G protein with a big role in the hypothalamic response to neuronal activation. Greenwood MP, Greenwood M, Mecawi AS, Antunes-Rodrigues J, Paton JF, Murphy D. Mol Brain. 2016 Jan 7;9(1):1. doi: 10.1186/s13041-015-0182-2. PubMed
WNT/beta-catenin signaling mediates human neural crest induction via a pre-neural border intermediate. Leung AW, Murdoch B, Salem AF, Prasad MS, Gomez GA, Garcia-Castro MI. Development. 2016 Feb 1;143(3):398-410. doi: 10.1242/dev.130849. PubMed
Constitutive p53 heightens mitochondrial apoptotic priming and favors cell death induction by BH3 mimetic inhibitors of BCL-xL. Le Pen J, Laurent M, Sarosiek K, Vuillier C, Gautier F, Montessuit S, Martinou JC, Letai A, Braun F, Juin PP. Cell Death Dis. 2016 Feb 4;7:e2083. doi: 10.1038/cddis.2015.400. PubMed
CDCP1 cleavage is necessary for homodimerization-induced migration of triple-negative breast cancer. Wright HJ, Arulmoli J, Motazedi M, Nelson LJ, Heinemann FS, Flanagan LA, Razorenova OV. Oncogene. 2016 Feb 15. doi: 10.1038/onc.2016.7. PubMed
Increased risk of interstitial lung disease in children with a single R288K variant of ABCA3. Wittmann T, Frixel S, Hoppner S, Schindlbeck U, Schams A, Kappler MV, Hegermann J, Wrede C, Liebisch G, Vierzig A, Zacharasiewicz A, Kopp M, Poets CF, Baden W, Hartl D, Van Kaam AH, Lohse P, Aslanidis C, Zarbock R, Griese M. Mol Med. 2016 Feb 26. pii: molmed.2015.00244. doi: 10.2119/molmed.2015.00244. PubMed
E-Cadherin repression increases amount of cancer stem cells in human A549 lung adenocarcinoma and stimulates tumor growth. Farmakovskaya M, Khromova N, Rybko V, Dugina V, Kopnin B, Kopnin P. Cell Cycle. 2016 Apr 17;15(8):1084-92. doi: 10.1080/15384101.2016.1156268. PubMed
Deacetylation Assays to Unravel the Interplay between Sirtuins (SIRT2) and Specific Protein-substrates. Song HY, Park SH, Kang HJ, Vassilopoulos A. J Vis Exp. 2016 Feb 27;(108). doi: 10.3791/53563. PubMed
A homeobox protein, NKX6.1, up-regulates interleukin-6 expression for cell growth in basal-like breast cancer cells. Li W, Itou J, Tanaka S, Nishimura T, Sato F, Toi M. Exp Cell Res. 2016 May 1;343(2):177-89. doi: 10.1016/j.yexcr.2016.03.023. Epub 2016 Mar 28. PubMed
A CRISPR-Based Toolbox for Studying T Cell Signal Transduction. Chi S, Weiss A, Wang H. Biomed Res Int. 2016;2016:5052369. doi: 10.1155/2016/5052369. Epub 2016 Feb 1. PubMed
ISL1 and JMJD3 synergistically control cardiac differentiation of embryonic stem cells. Wang Y, Li Y, Guo C, Lu Q, Wang W, Jia Z, Chen P, Ma K, Reinberg D, Zhou C. Nucleic Acids Res. 2016 Apr 21. pii: gkw301. PubMed
Highly variable cancer subpopulations that exhibit enhanced transcriptome variability and metastatic fitness. Nguyen A, Yoshida M, Goodarzi H, Tavazoie SF. Nat Commun. 2016 May 3;7:11246. doi: 10.1038/ncomms11246. PubMed
KLF4 transcriptionally activates non-canonical WNT5A to control epithelial stratification. Tetreault MP, Weinblatt D, Shaverdashvili K, Yang Y, Katz JP. Sci Rep. 2016 May 17;6:26130. doi: 10.1038/srep26130. PubMed
Crumbs 3b promotes tight junctions in an ezrin-dependent manner in mammalian cells. Tilston-Lunel AM, Haley KE, Schlecht NF, Wang Y, Chatterton AL, Moleirinho S, Watson A, Hundal HS, Prystowsky MB, Gunn-Moore FJ, Reynolds PA. J Mol Cell Biol. 2016 Apr 18. pii: mjw020. PubMed
CITED2 Modulates Breast Cancer Metastatic Ability Through Effects on IKKalpha. Jayaraman S, Doucet M, Lau WM, Kominsky SL. Mol Cancer Res. 2016 May 23. pii: molcanres.0081.2016. PubMed
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