Skip to main content
Holiday Schedule: Addgene will be closed November 26th & 27th for the Thanksgiving Holiday. Order processing and shipping may be delayed during this week. For questions about your shipment please contact [email protected].
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected] Learn more

COVID-19 and Coronavirus Plasmids & Resources


Please Note: We are automatically prioritizing orders related to ongoing coronavirus and COVID-19 research. Additionally, if you would like to deposit materials related to coronavirus or COVID-19 research, please email us at [email protected].


The global research community is moving quickly to expand the knowledge and understanding of COVID-19 and related coronaviruses. To assist with this effort Addgene will maintain this plasmid collection page, which outlines various plasmids available and those coming soon. Additionally, we have linked to collections of open-access articles, protocols, and other resource collections related to COVID-19 that may be of use to scientists.

Background

The Coronavirus Disease-2019 (COVID-19) pandemic is caused by a novel virus strain from the Coronaviridae family called SARS-CoV-2. Scientists have been working at lightning speed to elucidate as much as they can about this novel virus. It is now known that SARS-CoV-2 entry, like that of SARS-CoV and MERS CoV, depends on binding of the viral spike (S) protein to cellular receptors. The cellular receptor for SARS-CoV-2 and SARS-CoV is hACE2, an angiotensin receptor. Another key step is the priming of the S protein by host cell proteases. The S protein of SARS-CoV-2 is primed by the serine protease TMPRSS2.

Image credit: Maya Kostman for the Innovative Genomics Institute
Single virion with all parts labeled

Addgene COVID-19 Resources

The following types of resources can be found on this page:

  • SARS-CoV-2 Plasmids: Plasmids that are available or coming soon containing SARS-CoV-2 sequences.
  • SARS-CoV Plasmids: Plasmids that are available containing SARS-CoV (SARS classic) sequences.
  • Human Targets: Plasmids containing human sequences linked to SARS-CoV-2 infection.
  • General Tools: Plasmids expressing Cas12a/Cas13a, Reverse Transcriptases, etc. that may be useful for detection assays and more.
  • Research Articles: A list of free access articles on COVID-19 research.
  • Protocols: Protocols that may be useful for COVID-19 research.

Plasmids

SARS-CoV-2 Plasmids