We narrowed to 10,156 results for: ada

1. pDF0237 pCMV - dead huDisCas7-11 - NES - huADAR2

   Plasmid

   #172510

   Purpose

   Encodes human codon optimized catalytically dead DisCas7-11-NES-huADAR2 fusion protein alone for expression in mammalian cells

   Depositor

   Omar Abudayyeh, Jonathan Gootenberg

   Article

   Ozcan et al Nature. 2021 Sep 6. pii: 10.1038/s41586-

   Insert

   pCMV - dead huDisCas7-11 - NES - huADAR2
   

   Expression

   Mammalian

   Available Since

   Oct. 7, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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2. pAAV-hSyn-ADAR2-sesRNA-tTA2-W3SL

   Plasmid

   #192068

   Purpose

   Expression of ADAR2, sesRNA in mammalian cells with hSyn promoter, with tTA2 as efRNA and ADAR2 overexpression.

   Depositor

   Josh Huang

   Article

   Qian et al Nature. 2022 Oct;610(7933):713-721. doi:

   Insert

   sesRNA for mouse Ctip2
   

   Use

   AAV

   Expression

   Mammalian

   Promoter

   hSyn

   Available Since

   Jan. 19, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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3. All-in-one split-ADAR2(E488Q, N496F)

   Plasmid

   #170148

   Purpose

   AAV vector carrying ADAR2-DDC(E488Q, N496F)-λN-P2A-MCP-ADAR2-DDN with a nuclear export signal

   Depositor

   Prashant Mali

   Article

   Katrekar et al Elife. 2022 Jan 19;11. pii: 75555. doi:

   Insert

   ADAR2-DDC(E488Q, N496F)-λN-P2A-MCP-ADAR2-DDN
   

   Use

   AAV

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Feb. 25, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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4. pcDNA3.2-V5-DEST-hADAM10(aa1-213)-GST

   Plasmid

   #189562

   Purpose

   Protein expression ADAM10 in mammalian cells. Contains only prodomain--amino acids 1-213

   Depositor

   Haian Fu

   Insert

   truncated ADAM metallopeptidase domain 10 (ADAM10 Human)
   

   Tags

   GST

   Expression

   Mammalian

   Mutation

   contains aa 1-213

   Available Since

   Nov. 11, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. FLAG-ADA add back mutant pCMV5

   Plasmid

   #17554

   Depositor

   Domenico Accili

   Article

   Kitamura et al J Clin Invest. 2007 Sep . 117(9):2477-85

   Insert

   FLAG-FoxO1-ADA
   

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   siRNA-resistant Foxo1 by replacing 3 residues (un…

   Available Since

   Oct. 17, 2008

   Availability

   Academic Institutions and Nonprofits only

6. EW446 CMV-TO-ADAR2dd(E488Q, T501A) (FLP-IN)

   Plasmid

   #236125

   Purpose

   Plasmid encoding free ADAR2dd under control of CMV promoter with two TetR binding sites

   Depositor

   Xiaojing Gao

   Article

   Wolfsberg et al bioRxiv 2025.02.24.639918

   Insert

   ADAR2dd (ADARB1 Synthetic, Human)
   

   Expression

   Mammalian

   Mutation

   E488Q, T501A

   Promoter

   CMV promoter with two TetR binding sites

   Available Since

   April 9, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. XZ088 (IVT) CMV-TO-T7-CCR6-V2-ADAR2dd-hybridUTR3

   Plasmid

   #233421

   Purpose

   IVT template for CCR6-V2-ADAR2dd(E488Q, T501A)

   Depositor

   Xiaojing Gao

   Article

   Zhang et al Nat Chem Biol. 2025 Mar 28. doi: 10.1038

   Insert

   T7-CCR6-V2-ADAR2dd-hybridUTR3
   

   Expression

   Mammalian

   Mutation

   E488Q, T501A on ADAR2dd

   Promoter

   CMV

   Available Since

   April 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. XZ387 (IVT) CMV-TO-T7-AVPR2-V2-ADAR2dd-hybridUTR3

   Plasmid

   #233423

   Purpose

   IVT template for AVPR2-V2-ADAR2dd(E488Q, T501A)

   Depositor

   Xiaojing Gao

   Article

   Zhang et al Nat Chem Biol. 2025 Mar 28. doi: 10.1038

   Insert

   T7-AVPR2-V2-ADAR2dd-hybridUTR3
   

   Expression

   Mammalian

   Mutation

   E488Q, T501A on ADAR2dd

   Promoter

   CMV

   Available Since

   April 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. LSM101 CMV-TO-ADAR2dd(E488Q,T501A)-MCP

   Plasmid

   #233432

   Purpose

   ADAR2dd(E488Q,T501A)-MCP (positive control that fuses ADAR2dd and MCP on the same protein)

   Depositor

   Xiaojing Gao

   Article

   Zhang et al Nat Chem Biol. 2025 Mar 28. doi: 10.1038

   Insert

   ADAR2dd-tdMCP
   

   Expression

   Mammalian

   Mutation

   E488Q, T501A on ADAR2dd

   Promoter

   CMV

   Available Since

   April 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. XZ031 CMV-TO-CCR6-ADAR2dd(E488Q, T501A)

    Plasmid

    #233393

    Purpose

    CCR6-ADAR2dd(E488Q, T501A) with a short 4 amino acid linker and no V2 tail

    Depositor

    Xiaojing Gao

    Article

    Zhang et al Nat Chem Biol. 2025 Mar 28. doi: 10.1038

    Insert

    CCR6-ADAR2dd
    

    Expression

    Mammalian

    Mutation

    E488Q, T501A on ADAR2dd

    Promoter

    CMV

    Available Since

    April 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. XZ032 CMV-TO-CCR6-V2-ADAR2dd(E488Q, T501A)

    Plasmid

    #233394

    Purpose

    CCR6-V2-ADAR2dd(E488Q, T501A) with a short 4 amino acid linker and V2 tail

    Depositor

    Xiaojing Gao

    Article

    Zhang et al Nat Chem Biol. 2025 Mar 28. doi: 10.1038

    Insert

    CCR6-ADAR2dd
    

    Expression

    Mammalian

    Mutation

    E488Q, T501A on ADAR2dd

    Promoter

    CMV

    Available Since

    April 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pAAV-EFS-TadA8e-Sauri-U6-Camk2d sgRNA1

    Plasmid

    #220117

    Purpose

    Expresses SauriABE8e by EFS promoter and sgRNA targeting murine Camk2d start codon site by U6 promoter

    Depositor

    Yuxuan Guo

    Article

    Liu et al Circ Res. 2025 Jan 16. doi: 10.1161/CIRC

    Insert

    TadA8e, nSauriCas9
    

    Use

    AAV

    Promoter

    EFS

    Available Since

    Jan. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pAAV-EFS-TadA8e-Sauri-U6-Camk2d sgRNA6

    Plasmid

    #220118

    Purpose

    Expresses SauriABE8e by EFS promoter and sgRNA targeting murine Camk2d intron6 5' splice site by U6 promoter

    Depositor

    Yuxuan Guo

    Article

    Liu et al Circ Res. 2025 Jan 16. doi: 10.1161/CIRC

    Insert

    TadA8e, nSauriCas9
    

    Use

    AAV

    Promoter

    EFS

    Available Since

    Jan. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pAAV-EFS-TadA8e-Sauri-U6-Camk2d sgRNA7

    Plasmid

    #220119

    Purpose

    Expresses SauriABE8e by EFS promoter and sgRNA targeting murine Camk2d intron7 5' splice site by U6 promoter

    Depositor

    Yuxuan Guo

    Article

    Liu et al Circ Res. 2025 Jan 16. doi: 10.1161/CIRC

    Insert

    TadA8e, nSauriCas9
    

    Use

    AAV

    Promoter

    EFS

    Available Since

    Jan. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pAAV-MYL2-TadA8e-Sauri-U6-Camk2d sgRNA1

    Plasmid

    #220120

    Purpose

    Expresses SauriABE8e by MYL2 promoter and sgRNA targeting murine Camk2d start codon site by U6 promoter

    Depositor

    Yuxuan Guo

    Article

    Liu et al Circ Res. 2025 Jan 16. doi: 10.1161/CIRC

    Insert

    MYL2, TadA, nSauriCas9
    

    Use

    AAV

    Promoter

    MYL2

    Available Since

    Jan. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. pAAV-MYL2-TadA8e-Sauri-U6-Camk2d sgRNA6

    Plasmid

    #220122

    Purpose

    Expresses SauriABE8e by MYL2 promoter and sgRNA targeting murine Camk2d intron6 5' splice site by U6 promoter

    Depositor

    Yuxuan Guo

    Article

    Liu et al Circ Res. 2025 Jan 16. doi: 10.1161/CIRC

    Insert

    MYL2, TadA, nSauriCas9
    

    Use

    AAV

    Promoter

    MYL2

    Available Since

    Jan. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pAAV-MYL2-TadA8e-Sauri-U6-Camk2d sgRNA7

    Plasmid

    #220124

    Purpose

    Expresses SauriABE8e by MYL2 promoter and sgRNA targeting murine Camk2d intron7 5' splice site by U6 promoter

    Depositor

    Yuxuan Guo

    Article

    Liu et al Circ Res. 2025 Jan 16. doi: 10.1161/CIRC

    Insert

    MYL2, TadA, nSauriCas9
    

    Use

    AAV

    Promoter

    MYL2

    Available Since

    Jan. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. pAAV-MYL2-HA-TadA8e-Sauri-U6-Camk2d sgRNA7

    Plasmid

    #220127

    Purpose

    Expresses SauriABE8e by MYL2 promoter and sgRNA targeting murine Camk2d intron7 5' splice site by U6 promoter, and add an HA tag fused to TadA

    Depositor

    Yuxuan Guo

    Article

    Liu et al Circ Res. 2025 Jan 16. doi: 10.1161/CIRC

    Insert

    MYL2, TadA, nSauriCas9
    

    Use

    AAV

    Tags

    HA tag

    Promoter

    MYL2

    Available Since

    Jan. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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19. pAAV-EFS-TadA8e-Nme2-U6-sgRNA scaffold

    Plasmid

    #226933

    Purpose

    Encoding Nme2ABE8e and sgRNA cassette on a single AAV

    Depositor

    Yuxuan Guo

    Article

    Liu et al Circ Res. 2025 Jan 16. doi: 10.1161/CIRC

    Insert

    TadA8e, nNme2Cas9
    

    Use

    AAV

    Promoter

    EFS

    Available Since

    Jan. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. pAAV-EFS-TadA8e-SaKKH-U6-sgRNA scaffold

    Plasmid

    #226935

    Purpose

    Encoding SaKKHABE8e and sgRNA cassette on a single AAV

    Depositor

    Yuxuan Guo

    Article

    Liu et al Circ Res. 2025 Jan 16. doi: 10.1161/CIRC

    Insert

    TadA8e, nSaKKHCas9
    

    Use

    AAV

    Promoter

    EFS

    Available Since

    Jan. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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