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Human Base Editing Sensor Library

Pooled Library

#179218

Purpose

sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

Depositor

Lukas Dow

Article

Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

Expression

Mammalian

Use

Lentiviral

Available Since

June 16, 2022

Availability

Academic Institutions and Nonprofits only
Mouse Base Editing Sensor Library

Pooled Library

#179217

Purpose

sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

Depositor

Lukas Dow

Article

Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

Expression

Mammalian

Use

Lentiviral

Available Since

June 16, 2022

Availability

Academic Institutions and Nonprofits only
RNA-Binding Protein Pooled CRISPR Knockout In Vivo Library

Pooled Library

#250988

Purpose

CRISPR knockout library targets 206 RBPs with 5 single-guide RNAs (sgRNAs) per target. It is constructed in the lenti-CRISPR V2 backbone, enabling doxycycline-inducible expression of Cas9.

Depositor

Eugene Yeo

Article

Tankka et al Cancer Res. 2025 Dec 18:10.1158/0008-547

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

March 10, 2026

Availability

Academic Institutions and Nonprofits only
pDONR221_SLC25A4

Plasmid

#131982

Purpose

Gateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors

Depositor

RESOLUTE Consortium, Giulio Superti-Furga

Article

Superti-Furga et al Nat Rev Drug Discov. 2020 Jul;19(7):429-

Insert

SLC25A4 (SLC25A4 Human)

Expression

Mammalian

Available Since

Oct. 22, 2019

Availability

Industry, Academic Institutions, and Nonprofits

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pDONR221-SLC25A4_STOP

Plasmid

#161148

Purpose

Gateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors. Contains a STOP codon at the end of the codon-optimized ORF sequence.

Depositor

RESOLUTE Consortium, Giulio Superti-Furga

Article

Superti-Furga et al Nat Rev Drug Discov. 2020 Jul;19(7):429-

Insert

SLC25A4 (SLC25A4 Human)

Expression

Mammalian

Available Since

June 21, 2021

Availability

Industry, Academic Institutions, and Nonprofits

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pDONR221-SLC25A4_STOP

Plasmid

#161148

Purpose

Gateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors. Contains a STOP codon at the end of the codon-optimized ORF sequence.

Depositor

RESOLUTE Consortium, Giulio Superti-Furga

Article

Superti-Furga et al Nat Rev Drug Discov. 2020 Jul;19(7):429-

Insert

SLC25A4 (SLC25A4 Human)

Expression

Mammalian

Available Since

June 21, 2021

Availability

Industry, Academic Institutions, and Nonprofits

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pEF2-FL-hMer_gR1

Plasmid

#225993

Purpose

Expresses a chimeric contruct having N-terminal human MerTK and C-terminal human Interferon Gamma Receptor

Depositor

Raymond Birge, Sergei Kotenko

Article

Tsou et al J Biol Chem. 2014 Sep 12;289(37):25750-6

Insert

human MerTK N-Terminal human Interferon Gamma R1 Receptor C-Terminal fusion (MERTK, IFNGR1 Human)

Expression

Mammalian

Promoter

EF1-a

Available Since

Nov. 26, 2024

Availability

Academic Institutions and Nonprofits only

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pEF2-FL-hTyro_gR1

Plasmid

#225995

Purpose

Expresses a chimeric contruct having N-terminal human Tyro3 and C-terminal human Interferon Gamma Receptor

Depositor

Raymond Birge, Sergei Kotenko

Article

Tsou et al J Biol Chem. 2014 Sep 12;289(37):25750-6

Insert

human Tyro3 N-Terminal human Interferon Gamma R1 Receptor C-Terminal fusion (TYRO3, IFNGR1 Human)

Expression

Mammalian

Promoter

EF1-a

Available Since

Nov. 26, 2024

Availability

Academic Institutions and Nonprofits only

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pEF2-FL-hAxl_gR1

Plasmid

#225994

Purpose

Expresses a chimeric contruct having N-terminal human Axl and C-terminal human Interferon Gamma Receptor

Depositor

Raymond Birge, Sergei Kotenko

Article

Tsou et al J Biol Chem. 2014 Sep 12;289(37):25750-6

Insert

human Axl N-Terminal human Interferon Gamma R1 Receptor C-Terminal fusion (AXL, IFNGR1 Human)

Expression

Mammalian

Promoter

EF1-a

Available Since

Nov. 26, 2024

Availability

Academic Institutions and Nonprofits only

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pEF2-EFGR-hAxl

Plasmid

#225997

Purpose

Expresses a chimeric contruct having N-terminal human EGFR and C-terminal human Axl

Depositor

Raymond Birge, Sergei Kotenko

Article

Kimani et al Cell Commun Signal. 2016 Sep 6;14(1):19.

Insert

human EGFR N-Terminal human Axl C-Terminal Fusion (EGFR, AXL Human)

Expression

Mammalian

Promoter

EF1-a

Available Since

Nov. 8, 2024

Availability

Academic Institutions and Nonprofits only

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pEF2-EFGR-hMer

Plasmid

#225996

Purpose

Expresses a chimeric construct having N-terminal human EGFR and C-terminal human MerTK

Depositor

Raymond Birge, Sergei Kotenko

Article

Kimani et al Cell Commun Signal. 2016 Sep 6;14(1):19.

Insert

human EGFR N-Terminal human MerTK C-Terminal Fusion (EGFR, MERTK Human)

Expression

Mammalian

Promoter

EF1-a

Available Since

Nov. 8, 2024

Availability

Academic Institutions and Nonprofits only

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pEF2-EFGR-hTyro

Plasmid

#225998

Purpose

Expresses a chimeric construct having N-terminal human EGFR and C-terminal human Tyro3

Depositor

Raymond Birge, Sergei Kotenko

Article

Kimani et al Cell Commun Signal. 2016 Sep 6;14(1):19.

Insert

human EGFR N-Terminal human Tyro3 C-Terminal Fusion (EGFR, TYRO3 Human)

Expression

Mammalian

Promoter

EF1-a

Available Since

Nov. 21, 2024

Availability

Academic Institutions and Nonprofits only

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pEPIP_PepTile_40merFragments_65CancerDrivers

Pooled Library

#172109

Purpose

Lentiviral peptide expression library for overexpression fitness screening

Depositor

Prashant Mali

Article

Ford et al Cell Syst. 2021 Jul 21;12(7):716-732.e7.

Use

Lentiviral

Available Since

Oct. 21, 2021

Availability

Academic Institutions and Nonprofits only
pSMAL-CellTag-V1

Pooled Library

#115643

Purpose

Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

Depositor

Samantha Morris

Article

Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

Has Service

Concentrated Lentiviral Prep

Expression

Mammalian

Species

Synthetic

Use

Lentiviral

Available Since

Dec. 5, 2018

Availability

Academic Institutions and Nonprofits only
pSMAL-CellTag-V2

Pooled Library

#115644

Purpose

Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

Depositor

Samantha Morris

Article

Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

Has Service

Concentrated Lentiviral Prep

Expression

Mammalian

Species

Synthetic

Use

Lentiviral

Available Since

Dec. 5, 2018

Availability

Academic Institutions and Nonprofits only
pSMAL-CellTag-V3

Pooled Library

#115645

Purpose

Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

Depositor

Samantha Morris

Article

Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

Has Service

Concentrated Lentiviral Prep

Expression

Mammalian

Species

Synthetic

Use

Lentiviral

Available Since

Dec. 5, 2018

Availability

Academic Institutions and Nonprofits only
pBD-PYR1-TSM_library

Pooled Library

#241288

Purpose

Library of pBD-PYR1 triple site mutants for yeast-based sensor screens

Depositor

Sean Cutler

Article

Tian et al bioRxiv [Preprint]. 2025 May 15:2025.05.

Expression

Yeast

Species

Arabidopsis thaliana

Available Since

Oct. 23, 2025

Availability

Academic Institutions and Nonprofits only
pSMAL-CellTag-multi-v1 barcode library

Pooled Library

#206045

Purpose

The CellTag multi library of barcodes can be used to clonally label cells with DNA barcodes. These barcodes can be profiled directly with single-cell RNA and ATAC sequencing, to allow clonal tracking

Depositor

Samantha Morris

Article

Jindal et al Nat Biotechnol. 2023 Sep 25. doi: 10.103

Use

Lentiviral

Available Since

Nov. 2, 2023

Availability

Academic Institutions and Nonprofits only
Escherichia coli DH10B-MOB

Bacterial Strain

#229395

Purpose

Escherichia coli DH10B DAP-auxotrophic strain containing an integrated RK2/RP4 mobilization vector to conjugate plasmids with an IncP origin of transfer (modified pTA-Mob 2.0, AddGene Plasmid #149662)

Depositor

Michael Springer

Article

Soltysiak et al ACS Synth Biol. 2025 Apr 18;14(4):1173-1

Bacterial Resistance

60 ug/mL of DAP

Species

Escherichia coli

Available Since

March 24, 2025

Availability

Academic Institutions and Nonprofits only
39R861+

Bacterial Strain

#119737

Purpose

Six stable plasmids can be used as size standards

Depositor

Ruth Hall

Article

Moran et al Plasmid. 2019 Mar;102:6-9. doi: 10.1016/

Bacterial Resistance

None

Available Since

Sept. 12, 2019

Availability

Academic Institutions and Nonprofits only