164,824 results

1. AICSDP-079:DCP1A-mEGFP

   Plasmid

   #193922

   Purpose

   Homology arms and mEGFP-SRA for N-terminus tagging of human DCP1A

   Depositor

   Allen Institute for Cell Science

   Insert

   DCP1A Homology Arms with mEGFP-SRA (DCP1A Human)
   

   Use

   CRISPR; Donor template

   Tags

   mEGFP-linker

   Expression

   Mutation

   homology arms contain point mutations to disrupt …

   Promoter

   Available since

   Dec. 22, 2022

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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2. pSF4 CMV intron renilla TRICK CTE polyA

   Plasmid

   #84443

   Purpose

   TRICK reporter mRNA

   Depositor

   Jeffrey Chao

   Article

   Halstead et al Science. 2015 Mar 20;347(6228):1367-671.

   Insert

   Renill-TRICK
   

   Use

   Luciferase; Frt

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Tet-CMV

   Available since

   Nov. 29, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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3. pX330-PITCh-H3C2

   Plasmid

   #207780

   Purpose

   Expresses SpCas9, the PITCh gRNA, and a sgRNA targeting the C-terminus of H3C2 for knock-in.

   Depositor

   Laurence Pelletier

   Article

   Philip et al EMBO J. 2024 Dec 12. doi: 10.1038/s44318

   Insert

   sgRNA Targeting C-terminus of H3C2 (H3C2 Human)
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Dec. 1, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. PRKAG3 gRNA (BRDN0001145578)

   Plasmid

   #77295

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human PRKAG3

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   PRKAG3 (PRKAG3 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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5. PRKAG3 gRNA (BRDN0001147132)

   Plasmid

   #77296

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human PRKAG3

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   PRKAG3 (PRKAG3 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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6. PRKAG3 gRNA (BRDN0001146704)

   Plasmid

   #77294

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human PRKAG3

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   PRKAG3 (PRKAG3 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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7. TFORF2033

   Plasmid

   #143567

   Purpose

   Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

   Depositor

   Feng Zhang

   Article

   Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

   Insert

   OSR1 (OSR1 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   EF1a

   Available since

   April 27, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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8. pcDNA4/TO/GFPZNF598-9P-9A

   Plasmid

   #141192

   Purpose

   Expresses GFP-ZNF598 mutated in polyproline streches in mammalian cells, can be used to make inducible cell line

   Depositor

   Simon Bekker-Jensen

   Article

   Tollenaere et al Cell Rep. 2019 Mar 26;26(13):3511-3521.e

   Insert

   ZNF598 (ZNF598 Human)
   

   Use

   Tags

   GFP

   Expression

   Mammalian

   Mutation

   all 3 proline repeats are mutated to Alanine (9xP…

   Promoter

   CMV

   Available since

   June 5, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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9. pSKB3.MPN348

   Plasmid

   #11437

   Depositor

   Sung-Hou Kim

   Article

   Chen et al Proteins. 2004 Sep 1. 56(4):839-43.

   Insert

   methenyltetrahydrofolate synthetase
   

   Use

   Tags

   6x His and TEV cleavage site

   Expression

   Bacterial

   Mutation

   Promoter

   Available since

   April 10, 2006

   Availability

   Academic Institutions and Nonprofits only

   

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10. FLAG-sc-WDR59-SEC13

    Plasmid

    #237416

    Purpose

    Transient expression of N-terminally FLAG-tagged human WDR59-SEC13 "single chain" in the GATOR2 complex

    Depositor

    David Sabatini

    Article

    Valenstein et al Nature. 2025 Aug 20. doi: 10.1038/s41586

    Insert

    WDR59-SEC13 fusion (WDR59, SEC13 Human)
    

    Use

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Aug. 20, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. sc-MIOS-SEH1L

    Plasmid

    #237417

    Purpose

    Transient expression of human MIOS-SEH1L "single chain" in the GATOR2 complex

    Depositor

    David Sabatini

    Article

    Valenstein et al Nature. 2025 Aug 20. doi: 10.1038/s41586

    Insert

    MIOS-SEH1L fusion (MIOS, SEH1L Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Aug. 20, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. sc-WDR24-SEH1L

    Plasmid

    #237418

    Purpose

    Transient expression of human WDR24-SEH1L "single chain" in the GATOR2 complex

    Depositor

    David Sabatini

    Article

    Valenstein et al Nature. 2025 Aug 20. doi: 10.1038/s41586

    Insert

    WDR24-SEH1L fusion (WDR24, SEH1L Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Aug. 20, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. mCherry_SeV_Nucleoprotein

    Plasmid

    #228806

    Purpose

    Expression of Sendai virus Nucleoprotein

    Depositor

    Shravanti Rampalli

    Article

    Biligiri et al PLOS Biology 22(11): e3002871.

    Insert

    Nucleoprotein
    

    Use

    Tags

    mCherry

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Aug. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pLentiCRISPRv2_cGAS_gRNA_3

    Plasmid

    #235531

    Purpose

    gRNA against human cGAS

    Depositor

    Nicolas Manel

    Article

    Lahaye et al Cell. 2025 May 29:S0092-8674(25)00556-2.

    Insert

    cGAS (CGAS Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    July 17, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pAAV-CAG-GFP (AAV11)

    Viral Prep

    #37825-AAV11

    Purpose

    Ready-to-use AAV11 particles produced from pAAV-CAG-GFP (#37825). In addition to the viral particles, you will also receive purified pAAV-CAG-GFP plasmid DNA. CAG-driven GFP expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Edward Boyden

    Promoter

    CAG

    Tags

    GFP

    Available since

    July 16, 2025

    Availability

    Academic Institutions and Nonprofits only

16. pET28A-Rab8A

    Plasmid

    #228880

    Purpose

    Expression of His-tagged Rab8A in E. coli

    Depositor

    Sebastian Mathea

    Article

    Raig et al bioRxiv [Preprint]. 2025 Feb 13:2024.09.

    Insert

    RAB8A (RAB8A Human)
    

    Use

    Tags

    His tag

    Expression

    Bacterial

    Mutation

    residues 1-6 and 177-207 missing

    Promoter

    Available since

    Jan. 28, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. qTAG-KO-PGK-Blast

    Plasmid

    #227265

    Purpose

    Empty selectable Knock-Out donor cassette. Integrate homology arms to target the N-terminus insertion of a PGK-Blast cassette

    Depositor

    Laurence Pelletier

    Article

    Philip et al EMBO J. 2024 Dec 12. doi: 10.1038/s44318

    Type

    Empty backbone

    Use

    CRISPR; Donor cassette

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Nov. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. siRNA-resistant SigmaR1-mNeonGreen R119A

    Plasmid

    #226572

    Purpose

    Encodes mutant siRNA resistant SigmaR1 protein (substitution) labeled with mNeonGreen

    Depositor

    Gia Voeltz

    Article

    Sawyer et al Dev Cell. 2024 Jul 2:S1534-5807(24)00382

    Insert

    SigmaR1 (Sigma-1 Receptor) (SIGMAR1 Human)
    

    Use

    Tags

    mNeonGreen

    Expression

    Mammalian

    Mutation

    R119A

    Promoter

    Available since

    Nov. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. siRNA-resistant SigmaR1-mNeonGreen D188A

    Plasmid

    #226573

    Purpose

    Encodes mutant siRNA resistant SigmaR1 protein (substitution) labeled with mNeonGreen

    Depositor

    Gia Voeltz

    Article

    Sawyer et al Dev Cell. 2024 Jul 2:S1534-5807(24)00382

    Insert

    SigmaR1 (Sigma-1 Receptor) (SIGMAR1 Human)
    

    Use

    Tags

    mNeonGreen

    Expression

    Mammalian

    Mutation

    D188A

    Promoter

    Available since

    Nov. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. siRNA-resistant SigmaR1-mNeonGreen F191A

    Plasmid

    #226571

    Purpose

    Encodes mutant siRNA resistant SigmaR1 protein (substitution) labeled with mNeonGreen

    Depositor

    Gia Voeltz

    Article

    Sawyer et al Dev Cell. 2024 Jul 2:S1534-5807(24)00382

    Insert

    SigmaR1 (Sigma-1 Receptor) (SIGMAR1 Human)
    

    Use

    Tags

    mNeonGreen

    Expression

    Mammalian

    Mutation

    F191A

    Promoter

    Available since

    Nov. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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