We narrowed to 10,957 results for: AGA

1. NFATc1-CRISPR-Nick 2/2 (PX461-EF1a-pSpCas9n(BB)-2A-GFP)

   Plasmid

   #75239

   Purpose

   CRISPR/Cas9 NICKASE plasmid against human NFATc1 (2/2)

   Depositor

   Ria Baumgrass

   Article

   Gabriel et al J Biol Chem. 2016 Sep 16. pii: jbc.M116.

   Insert

   sgRNA against NFATc1 (NFATC1 Human)
   

   Use

   CRISPR

   Tags

   Expression

   Mutation

   Promoter

   Available since

   June 8, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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2. pUAST-HA, Pbl-A PH+DH domains

   Plasmid

   #69793

   Purpose

   Pebble isoform A, PH and DH domains, in P element-based pUAST vector for Gal4-regulated expression in Drosophila.

   Depositor

   Arno Muller

   Article

   van Impel et al Development. 2009 Mar;136(5):813-22. doi

   Insert

   Pebble DH +PH domains (pbl Fly)
   

   Use

   P element-based puast vector for gal4-regulated e…

   Tags

   HA tag

   Expression

   Insect

   Mutation

   Pbl-A (NP_729306.1) amino acids 385-647.

   Promoter

   hsp70 promoter

   Available since

   Nov. 24, 2015

   Availability

   Academic Institutions and Nonprofits only

3. PIK3R4 gRNA (BRDN0001145724)

   Plasmid

   #75593

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human PIK3R4

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   PIK3R4 (PIK3R4 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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4. pIS1 ELOVL6

   Plasmid

   #60790

   Purpose

   Luciferase reporter to measure miR-155 mediated differential repression. Contains ELOVL6 3' UTR and wild-type miR-155 sites

   Depositor

   David Bartel

   Article

   Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi

   Insert

   ELOVL6 3'UTR and wild-type miR-155 binding site (ELOVL6 Human)
   

   Use

   Luciferase

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   thymidine kinase (HSV-TK promoter)

   Available since

   Oct. 20, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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5. pIS1 LPIN1

   Plasmid

   #60802

   Purpose

   Luciferase reporter to measure miR-155 mediated differential repression. Contains LPIN1 3' UTR and wild-type miR-155 sites

   Depositor

   David Bartel

   Article

   Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi

   Insert

   LPIN1 3'UTR and wild-type miR-155 binding site (LPIN1 Human)
   

   Use

   Luciferase

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   thymidine kinase (HSV-TK promoter)

   Available since

   May 18, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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6. pIS1 PELO

   Plasmid

   #60804

   Purpose

   Luciferase reporter to measure miR-155 mediated differential repression. Contains PELO 3' UTR and wild-type miR-155 sites

   Depositor

   David Bartel

   Article

   Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi

   Insert

   PELO 3'UTR and wild-type miR-155 binding site (PELO Human)
   

   Use

   Luciferase

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   thymidine kinase (HSV-TK promoter)

   Available since

   Oct. 20, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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7. pIS1 EPAS1

   Plasmid

   #60792

   Purpose

   Luciferase reporter to measure miR-155 mediated differential repression. Contains EPAS1 3' UTR and wild-type miR-155 sites

   Depositor

   David Bartel

   Article

   Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi

   Insert

   EPAS1 3'UTR and wild-type miR-155 binding site (EPAS1 Human)
   

   Use

   Luciferase

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   thymidine kinase (HSV-TK promoter)

   Available since

   Oct. 20, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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8. pKLV2-U6gRNA5(hTNF_2b)-PGKpuro2ABFP-W

   Plasmid

   #208426

   Purpose

   Lentiviral gRNA plasmid targeting human TNF gene, co-expression of BFP tag

   Depositor

   Sok Ching Cheong

   Article

   Chai et al Cancer Res Commun. 2024 Nov 1;4(11):2919

   Insert

   TNF (TNF Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   N/A

   Promoter

   human U6

   Available since

   July 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. pX458_mCherry-HP1a-gRNA-2

   Plasmid

   #237635

   Purpose

   Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to HP1a locus

   Depositor

   Denes Hnisz

   Article

   Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

   Insert

   HP1a gRNA (CBX5 Human)
   

   Use

   CRISPR

   Tags

   mCherry

   Expression

   Mutation

   Promoter

   Available since

   May 6, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pRK5_mEGFP-SS18-SSX1-KS

    Plasmid

    #237679

    Purpose

    For overexpression of mEGFP-SS18-SSX1-KS

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    SS18-SSX1-KS (SS18, SSX1 Human)
    

    Use

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pRK5_mEGFP-SS18-SSX1

    Plasmid

    #237678

    Purpose

    For overexpression of mEGFP-SS18-SSX1

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    SS18-SSX1 (SS18, SSX1 Human)
    

    Use

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pRK5_mEGFP-SS18-SSX2-KS

    Plasmid

    #237680

    Purpose

    For overexpression of mEGFP-SS18-SSX2-KS

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    SS18-SSX2-KS (SS18, SSX2 Human)
    

    Use

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pX458_mCherry-HP1a-gRNA-1

    Plasmid

    #237634

    Purpose

    Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to HP1a locus

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    HP1a gRNA (CBX5 Human)
    

    Use

    CRISPR

    Tags

    mCherry

    Expression

    Mutation

    Promoter

    Available since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pX458_mCherry-TCOF1-gRNA

    Plasmid

    #237633

    Purpose

    Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to TCOF1 locus

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    TCOF1 gRNA (TCOF1 Human)
    

    Use

    CRISPR

    Tags

    mCherry

    Expression

    Mutation

    Promoter

    Available since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pUC19_msfGFP-FUS-repair-tempate

    Plasmid

    #237684

    Purpose

    For knock-in msfGFP to FUS locus

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    FUS (FUS Human)
    

    Use

    CRISPR

    Tags

    msfGFP

    Expression

    Mutation

    Promoter

    Available since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. pRP.ABCA4 c.5461-10T

    Plasmid

    #226553

    Purpose

    Minigene encoding the ABCA4 c.5461-10T mutation

    Depositor

    Dave Wee

    Article

    Tabaglio et al Mol Ther Nucleic Acids. 2025 Jan 7;36(1)

    Insert

    ABCA4 (ABCA4 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    c.5461-10T intronic mutation

    Promoter

    CAG

    Available since

    Jan. 13, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pRP.ATM c.7865C>T

    Plasmid

    #226554

    Purpose

    Minigene encoding the ATM c.7865C>T mutation

    Depositor

    Dave Wee

    Article

    Tabaglio et al Mol Ther Nucleic Acids. 2025 Jan 7;36(1)

    Insert

    ATM (ATM Human)
    

    Use

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    c.7865C>T

    Promoter

    Available since

    Jan. 13, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. Lenti-SAM-Puro

    Plasmid

    #198713

    Purpose

    For expression of guide RNAs and the SAM transcriptional activator for CRISPRa in mammalian cells.

    Depositor

    Tyler Jacks

    Article

    Gaglia et al Cancer Cell. 2023 May 8;41(5):871-886.e1

    Inserts

    U6-MS2-gRNAscaffold
    EF1a-MPH-Puro
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1a and U6

    Available since

    Jan. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. Lenti-SAM-Cre

    Plasmid

    #198714

    Purpose

    For expression of guide RNAs, the SAM transcriptional activator for CRISPRa and Cre in mammalian cells

    Depositor

    Tyler Jacks

    Article

    Gaglia et al Cancer Cell. 2023 May 8;41(5):871-886.e1

    Inserts

    U6-MS2-gRNAscaffold
    Pgk-MPH-Cre
    

    Use

    Cre/Lox and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Pgk and U6

    Available since

    Jan. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pLX304-BCL-XL-F97W

    Plasmid

    #203572

    Purpose

    Expresses V5-tagged BCL-XL with partial drug resistance to A-1331852 in mammalian cells.

    Depositor

    Abhishek Chakraborty

    Article

    Grubb et al Clin Cancer Res. 2022 Nov 1;28(21):4689-

    Insert

    BCL2L1 (BCL2L1 Human)
    

    Use

    Lentiviral

    Tags

    V5-tagged

    Expression

    Mammalian

    Mutation

    Changed Phenylalanine 97 to Tryptophan for partia…

    Promoter

    CMV

    Available since

    Dec. 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. pET28.His.3C.20D3Q.Tau2N4R

    Plasmid

    #226397

    Purpose

    Expresses his-tagged, 3C-cleavable 20D3Q mutant 2N4R tau for recombinant protein production in bacteria

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT synthetic, Human)
    

    Use

    Tags

    His.3C

    Expression

    Bacterial

    Mutation

    20D3Q, Tau2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. pET28.His.3C.8D2Q.Tau2N4R

    Plasmid

    #226398

    Purpose

    Expresses his-tagged, 3C-cleavable 8D2Q mutant 2N4R tau for recombinant protein production in bacteria

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT synthetic, Human)
    

    Use

    Tags

    His.3C

    Expression

    Bacterial

    Mutation

    8D2Q.Tau2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. pET28.His.3C.86b.Tau2N4R

    Plasmid

    #226399

    Purpose

    Expresses his-tagged, 3C-cleavable, 86b (split luciferase fragment)-tagged WT 2N4R tau for recombinant protein production in bacteria

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT synthetic, Human)
    

    Use

    Tags

    His.3C.86b

    Expression

    Bacterial

    Mutation

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. SpyTag-RBD Omicron BQ.1.1

    Plasmid

    #214725

    Purpose

    Expresses SARS-CoV-2 Omicron BQ.1.1 RBD (receptor-binding domain from Spike) with N-terminal SpyTag fusion in mammalian cells

    Depositor

    Mark Howarth

    Article

    Hills et al Nat Nanotechnol. 2024 May 6. doi: 10.103

    Insert

    Receptor-Binding Domain (S SARS-CoV-2)
    

    Use

    Tags

    SpyTag

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    June 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. Quartet-SpyTag

    Plasmid

    #214726

    Purpose

    In mammalian cells expresses a Quartet of receptor-binding domains (RBDs) from the sarbecoviruses SHC014, Rs4081, RaTG13, and SARS-CoV-2 each separated by GS-linkers with a C-terminal SpyTag fusion

    Depositor

    Mark Howarth

    Article

    Hills et al Nat Nanotechnol. 2024 May 6. doi: 10.103

    Insert

    Quartet-SpyTag (S Synthetic)
    

    Use

    Tags

    SpyTag

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    June 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. SpyTag-Quartet

    Plasmid

    #214727

    Purpose

    In mammalian cells expresses a Quartet of receptor-binding domains (RBDs) from the sarbecoviruses SHC014, Rs4081, RaTG13, and SARS-CoV-2 each separated by GS-linkers with an N-terminal SpyTag fusion

    Depositor

    Mark Howarth

    Article

    Hills et al Nat Nanotechnol. 2024 May 6. doi: 10.103

    Insert

    SpyTag-Quartet (S Synthetic)
    

    Use

    Tags

    SpyTag

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    June 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. SpyTag-Alternate Quartet

    Plasmid

    #214728

    Purpose

    In mammalian cells expresses a Quartet of receptor-binding domains (RBDs) from the sarbecoviruses pang17, RmYN02, Rf1, and WIV1 each separated by GS-linkers with an N-terminal SpyTag fusion

    Depositor

    Mark Howarth

    Article

    Hills et al Nat Nanotechnol. 2024 May 6. doi: 10.103

    Insert

    SpyTag-Alternate Quartet
    

    Use

    Tags

    SpyTag

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    June 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. SpyTag-Quartet [SARS1]

    Plasmid

    #214729

    Purpose

    In mammalian cells expresses a Quartet of receptor-binding domains (RBDs) from the sarbecoviruses SHC014, Rs4081, RaTG13, and SARS-CoV each separated by GS-linkers with an N-terminal SpyTag fusion

    Depositor

    Mark Howarth

    Article

    Hills et al Nat Nanotechnol. 2024 May 6. doi: 10.103

    Insert

    SpyTag-Quartet [SARS1] (S Synthetic)
    

    Use

    Tags

    SpyTag

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    June 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. SpyTag-Kraken Quartet

    Plasmid

    #214730

    Purpose

    In mammalian cells expresses a Quartet of receptor-binding domains (RBDs) from the sarbecoviruses SHC014, Rs4081, RaTG13, and SARS-CoV-2 XBB.1.5 separated by GS-linkers with an N-terminal SpyTag

    Depositor

    Mark Howarth

    Article

    Hills et al Nat Nanotechnol. 2024 May 6. doi: 10.103

    Insert

    SpyTag-Kraken Quartet (S Synthetic)
    

    Use

    Tags

    SpyTag

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    June 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. SpyTag-Quartet_NoLinker

    Plasmid

    #214731

    Purpose

    In mammalian cells expresses a Quartet of receptor-binding domains (RBDs) from the sarbecoviruses SHC014, Rs4081, RaTG13, and SARS-CoV-2 with no linkers between the RBDs and an N-terminal SpyTag

    Depositor

    Mark Howarth

    Article

    Hills et al Nat Nanotechnol. 2024 May 6. doi: 10.103

    Insert

    SpyTag-Quartet_NoLinker (S Synthetic)
    

    Use

    Tags

    SpyTag

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    June 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge