We narrowed to 48,883 results for: des.1

1. pLenti-K36M TAIL[1-44]-3AID-HA-2A-mCherryBSD

   Plasmid

   #225872

   Purpose

   Lentiviral expression of AID degron tagged H3.3(K36M) histone tail corresponding to amino acids 1-44 and mCherry fused BlasticidinR

   Depositor

   Lacra Bintu

   Article

   Sinha et al bioRxiv [Preprint]. 2023 Oct 14:2023.10.

   Insert

   H3.3(K36M) amino acids 1-44 (H3-3A, H3-3B Human, Synthetic)
   

   Use

   Lentiviral and Synthetic Biology

   Tags

   3xAID HA and T2A-mCherry

   Expression

   Mammalian

   Mutation

   amino acids 1-44 from H3.3 K36M

   Promoter

   Available since

   Oct. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. K-to-R mutant NPRL3(1-569) in pLJM60, codon-optimized

   Plasmid

   #184563

   Purpose

   CMV-driven expression of an untagged mutant NPRL3 (core subunit of GATOR1) — codon-optimized sequence for stable expression in mammalian cells. All lysine residues were mutated to arginines.

   Depositor

   Kacper Rogala

   Article

   Valenstein et al Nature. 2022 Jul;607(7919):610-616. doi:

   Insert

   C16orf35, CGTHBA, FFEVF3, HS-40, MARE, NPR3, RMD11 (NPRL3 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   All lysines were mutated to arginines. Codon-opti…

   Promoter

   CMV

   Available since

   Nov. 23, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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3. pCSC-CMV-HA-Ast-3-NP-1-IRES-mCherry

   Plasmid

   #159631

   Purpose

   expresses HA Allatostatin-3, Neurophysin-1, IRES mCherry under the CSC promoter

   Depositor

   Andrew Allen, Ross Bathgate

   Article

   Ngo et al Cell Rep. 2020 Sep 15;32(11):108139. doi

   Insert

   Ast (AstA Fly)
   

   Use

   Lentiviral

   Tags

   HA, IRES, mCherry, and neurophysin-1

   Expression

   Mammalian

   Mutation

   Promoter

   CMV promoter

   Available since

   Oct. 30, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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4. Anti-Copper ATPase 1 (Menke's disease protein) [L60/4R]

   Plasmid

   #114502

   Purpose

   Mammalian Expression Plasmid of anti-Copper ATPase 1 (Menke's disease protein) (Human). Derived from hybridoma L60/4.

   Depositor

   James Trimmer

   Article

   Andrews et al Elife. 2019 Jan 22;8. pii: 43322. doi: 1

   Insert

   anti-Copper ATPase 1 (Menke's disease protein) (Homo sapiens) recombinant mouse monoclonal antibody (ATP7A Mouse)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   dual CMV

   Available since

   Feb. 22, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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5. pCDH-3_Flag-YTHDF2-RNA-MUT (nonsense mutation of sgYTHDF2-1)

   Plasmid

   #232948

   Purpose

   Expresses the RNA-binding-deficient mutant of YTHDF2 with synonymous mutations for resistance against sgYTHDF2-1-mediated knockdown

   Depositor

   Jianjun Chen

   Article

   Chen et al Cell. 2024 Dec 12:S0092-8674(24)01324-2.

   Insert

   YTHDF2-RNA-MUT (YTHDF2 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   RNA binding mutation (K416A+R527A), synonymous mu…

   Promoter

   Available since

   May 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. Anti-KCNT1/Slo2.2/Slack K+ channel [N3/26R-1]

   Plasmid

   #211599

   Purpose

   Mammalian Expression Plasmid of anti-KCNT1/Slo2.2/Slack K+ channel (Rat) subclass-switched IgG1 R-mAb. Derived from hybridoma N3/26.

   Depositor

   James Trimmer

   Article

   Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

   Insert

   anti-KCNT1/Slo2.2/Slack K+ channel (Rattus norvegicus) recombinant mouse monoclonal antibody. (Kcnt1 Mouse)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Dual CMV

   Available since

   Jan. 4, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. Anti-Copper ATPase 1 [L60/4R-rat IgG2a] - Chimeric

   Plasmid

   #231823

   Purpose

   Mammalian expression plasmid of anti-Copper ATPase 1 (Menke's disease protein) (Human) rat IgG2a R-mab. Derived from hybridoma L60/4.

   Depositor

   James Trimmer

   Article

   Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

   Insert

   Anti-Copper ATPase 1 (Menke's disease protein) (Homo sapiens) recombinant mouse monoclonal antibody (ATP7A Chimera: M. musculus (mouse)/R. norvegicus (rat))
   

   Use

   Affinity Reagent/ Antibody

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Dual CMV

   Available since

   Feb. 6, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pAAV.synP.DIO.EGFP.WPRE.hGH (AAV9)

   Viral Prep

   #100043-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV.synP.DIO.EGFP.WPRE.hGH (#100043). In addition to the viral particles, you will also receive purified pAAV.synP.DIO.EGFP.WPRE.hGH plasmid DNA. Synapsin-driven, Cre-dependent EGFP expression. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Ian Wickersham

   Promoter

   Syn

   Tags

   EGFP (Cre-dependent)

   Available since

   April 20, 2018

   Availability

   Academic Institutions and Nonprofits only

9. pAAV-hSyn-fDIO-hM4D(Gi)-mCherry-WPREpA (AAV8)

   Viral Prep

   #154867-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-hSyn-fDIO-hM4D(Gi)-mCherry-WPREpA (#154867). In addition to the viral particles, you will also receive purified pAAV-hSyn-fDIO-hM4D(Gi)-mCherry-WPREpA plasmid DNA. Syn-driven, Flp-dependent hM4D(Gi) receptor with an mCherry reporter for CNO-induced neuronal inhibition. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Ulrik Gether

   Article

   Runegaard et al eNeuro. 2018 Jun 18;5(3). pii: eN-NWR-03

   Promoter

   Human Synapsin-1

   Tags

   mCherry (Flp-dependent)

   Available since

   Aug. 19, 2022

   Availability

   Academic Institutions and Nonprofits only

10. CaMKII-somBiPOLES-mCerulean (AAV Retrograde)

    Viral Prep

    #154948-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from CaMKII-somBiPOLES-mCerulean (#154948). In addition to the viral particles, you will also receive purified CaMKII-somBiPOLES-mCerulean plasmid DNA. CamKII-driven expression of soma-targeted BiPOLES for optogenetic inhibition (blue light) and activation (red light). These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Simon Wiegert

    Article

    Vierock et al Nat Commun. 2021 Jul 26;12(1):4527. doi:

    Promoter

    CaMKIIa(0.4)

    Tags

    mCerulean

    Available since

    Sept. 1, 2021

    Availability

    Academic Institutions and Nonprofits only

11. hSyn-DIO-somBiPOLES-mCerulean (AAV Retrograde)

    Viral Prep

    #154951-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from hSyn-DIO-somBiPOLES-mCerulean (#154951). In addition to the viral particles, you will also receive purified hSyn-DIO-somBiPOLES-mCerulean plasmid DNA. Synapsin-driven, Cre-dependent expression of soma-targeted BiPOLES for optogenetic inhibition (blue light) and activation (red light). These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Simon Wiegert

    Article

    Vierock et al Nat Commun. 2021 Jul 26;12(1):4527. doi:

    Promoter

    Syn

    Tags

    mCerulean (Cre-dependent)

    Available since

    Sept. 1, 2021

    Availability

    Academic Institutions and Nonprofits only

12. pAAV-hSyn-EGFP (AAV1)

    Viral Prep

    #50465-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-hSyn-EGFP (#50465). In addition to the viral particles, you will also receive purified pAAV-hSyn-EGFP plasmid DNA. hSyn-driven EGFP expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Promoter

    Syn

    Tags

    EGFP

    Available since

    July 12, 2019

    Availability

    Academic Institutions and Nonprofits only

13. pAAV-hSyn-EGFP (AAV9)

    Viral Prep

    #50465-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-hSyn-EGFP (#50465). In addition to the viral particles, you will also receive purified pAAV-hSyn-EGFP plasmid DNA. hSyn-driven EGFP expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Promoter

    Syn

    Tags

    EGFP

    Available since

    May 28, 2019

    Availability

    Academic Institutions and Nonprofits only

14. pAAV-hSyn-EGFP (AAV5)

    Viral Prep

    #50465-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV-hSyn-EGFP (#50465). In addition to the viral particles, you will also receive purified pAAV-hSyn-EGFP plasmid DNA. hSyn-driven EGFP expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Promoter

    Syn

    Tags

    EGFP

    Available since

    Dec. 21, 2016

    Availability

    Academic Institutions and Nonprofits only

15. pAAV-hSyn-EGFP (AAV8)

    Viral Prep

    #50465-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-hSyn-EGFP (#50465). In addition to the viral particles, you will also receive purified pAAV-hSyn-EGFP plasmid DNA. hSyn-driven EGFP expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Promoter

    Syn

    Tags

    EGFP

    Available since

    Oct. 24, 2016

    Availability

    Academic Institutions and Nonprofits only

16. pAAV-hSyn-EGFP (AAV2)

    Viral Prep

    #50465-AAV2

    Purpose

    Ready-to-use AAV2 particles produced from pAAV-hSyn-EGFP (#50465). In addition to the viral particles, you will also receive purified pAAV-hSyn-EGFP plasmid DNA. hSyn-driven EGFP expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Promoter

    Syn

    Tags

    EGFP

    Available since

    Nov. 8, 2016

    Availability

    Academic Institutions and Nonprofits only

17. pAAV-hsyn-flex-Voltron-ST (AAV1)

    Viral Prep

    #119036-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-hsyn-flex-Voltron-ST (#119036). In addition to the viral particles, you will also receive purified pAAV-hsyn-flex-Voltron-ST plasmid DNA. Synapsin-driven, cre-dependent expression of genetically encoded fluorescent voltage indicator Voltron1 with a soma-targeting sequence. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Eric Schreiter

    Article

    Abdelfattah et al Science. 2019 Aug 1. pii: science.aav641

    Promoter

    Syn

    Tags

    None

    Available since

    April 10, 2019

    Availability

    Academic Institutions and Nonprofits only

18. pAAV-hSyn-fDIO-hM4D(Gi)-mCherry-WPREpA (AAV Retrograde)

    Viral Prep

    #154867-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-hSyn-fDIO-hM4D(Gi)-mCherry-WPREpA (#154867). In addition to the viral particles, you will also receive purified pAAV-hSyn-fDIO-hM4D(Gi)-mCherry-WPREpA plasmid DNA. Syn-driven, Flp-dependent hM4D(Gi) receptor with an mCherry reporter for CNO-induced neuronal inhibition. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Ulrik Gether

    Article

    Runegaard et al eNeuro. 2018 Jun 18;5(3). pii: eN-NWR-03

    Promoter

    Human Synapsin-1

    Tags

    mCherry (Flp-dependent)

    Available since

    Oct. 8, 2020

    Availability

    Academic Institutions and Nonprofits only

19. pAAV-hSyn-EGFP (AAV PHP.eB)

    Viral Prep

    #50465-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV-hSyn-EGFP (#50465). In addition to the viral particles, you will also receive purified pAAV-hSyn-EGFP plasmid DNA. hSyn-driven EGFP expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Promoter

    Syn

    Tags

    EGFP

    Available since

    Aug. 20, 2024

    Availability

    Academic Institutions and Nonprofits only

20. PB513B-1/TRE-hHNF1α-hHNF3β-hCEBPα-hCEBPβ-hCEBPγ-EF1α-Puro

    Plasmid

    #199550

    Purpose

    PiggyBac-based transposon vector plasmid which encodes the expression units of liver-enriched transcription factor genes (hHNF1α-hHNF3β-hCEBPα-hCEBPβ-hCEBP-γ) under control of the TRE/PCMVmin promoter

    Depositor

    Masamichi Kamihira

    Article

    Kitano et al Cells. 2022 Apr 1;11(7):1194. doi: 10.33

    Insert

    hHNF1α-hHNF3β-hCEBPα-hCEBPβ-hCEBPγ (HNF1A, FOXA2, CEBPB, CEBPA, CEBPG Human)
    

    Use

    Piggybac transposon vector

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    TRE+CMVmin promoter

    Available since

    Aug. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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