We narrowed to 34,521 results for: MUT

1. pDONR221-ARL4D-no stop

   Plasmid

   #67337

   Purpose

   hArl4D without stop codon in Gateway Entry vector

   Depositor

   Richard Kahn

   Article

   Kerr et al Cell Logist. 2015 Sep 21;5(3):e1090523.

   Insert

   ARL4D (ARL4D Human)
   

   Use

   Gateway entry vector

   Expression

   Bacterial

   Mutation

   bp 272 A to C; N91T mutation; bp 327 T to G; sil…

   Promoter

   None

   Available Since

   Oct. 5, 2015

   Availability

   Academic Institutions and Nonprofits only

2. pDEST53-LRRK2-G2019S

   Plasmid

   #25045

   Depositor

   Mark Cookson

   Article

   Greggio et al Neurobiol Dis. 2006 Aug . 23(2):329-41.

   Insert

   LRRK2 (LRRK2 Human)
   

   Tags

   GFP

   Expression

   Mammalian

   Mutation

   Glycine 2019 mutated to Serine

   Available Since

   June 17, 2010

   Availability

   Academic Institutions and Nonprofits only

   

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3. pcDNA3-myc-his-BACH1 K52R

   Plasmid

   #17643

   Depositor

   Ronny Drapkin

   Article

   Cantor et al Proc Natl Acad Sci U S A. 2004 Feb 24. 1

   Insert

   BACH1 (BRIP1 Human)
   

   Tags

   His and Myc

   Expression

   Mammalian

   Mutation

   The lysine residue at position 52 was changed to …

   Available Since

   April 4, 2008

   Availability

   Academic Institutions and Nonprofits only

4. pT7-7 asyn E46K

   Plasmid

   #105728

   Purpose

   Bacterial expression of mutant human alpha synuclein

   Depositor

   Hilal Lashuel

   Article

   Mbefo et al J Biol Chem. 2015 Apr 10;290(15):9412-27

   Insert

   alpha-synuclein E46K (SNCA Human)
   

   Expression

   Bacterial

   Mutation

   E46K

   Promoter

   T7

   Available Since

   April 2, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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5. pCDNA3.1 hSCN5A-L325R

   Plasmid

   #145373

   Purpose

   expresses mutant form of human Nav1.5 (L325R) found in patient with Brugada syndrome in mammalian cells

   Depositor

   Hugues Abriel

   Article

   Keller et al Cardiovasc Res. 2005 Aug 15;67(3):510-9.

   Insert

   sodium voltage-gated channel alpha subunit 5 (SCN5A Human)
   

   Expression

   Mammalian

   Mutation

   changed Leucine 325 to Arginine

   Promoter

   CMV

   Available Since

   Oct. 28, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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6. pcDNA6 asyn E46K

   Plasmid

   #105730

   Purpose

   Mammalian expression of mutant human alpha synuclein

   Depositor

   Hilal Lashuel

   Article

   Mbefo et al J Biol Chem. 2015 Apr 10;290(15):9412-27

   Insert

   alpha-synuclein E46K (SNCA Human)
   

   Expression

   Mammalian

   Mutation

   E46K

   Promoter

   CMV

   Available Since

   March 29, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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7. fluoPEER-GFP>BFP

   Plasmid

   #185477

   Purpose

   Fluorescent reporter for a Y66H mutation to convert a GFP to BFP.

   Depositor

   Sabine Fuchs

   Article

   Schene et al Nat Commun. 2022 Mar 1;13(1):1028. doi:

   Insert

   GFP-Y66-editing-site
   

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   July 28, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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8. pCDH-EF1-FHC-POLQ-DY2230AA

   Plasmid

   #64878

   Purpose

   lentiviral expression of human POLQ -DY2230AA mutant (a polymerase domain mutant)

   Depositor

   Richard Wood

   Article

   Yousefzadeh et al PLoS Genet. 2014 Oct 2;10(10):e1004654.

   Insert

   POLQ (POLQ Human)
   

   Use

   Lentiviral

   Tags

   FLAG and HA

   Expression

   Mammalian

   Mutation

   D2330A,Y2331A, in the DNA polymerase domain (POL)…

   Promoter

   EF1alpha

   Available Since

   July 11, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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9. pAAV-FLEX-hKCNQ3(R230C)-P2A-EGFP

   Plasmid

   #209194

   Purpose

   Cre-dependent expression of Kcnq3 with R230C mutation and GFP from the same transcript

   Depositor

   Larry Zweifel

   Article

   Gamal El-Din et al Proc Natl Acad Sci U S A. 2021 Nov 9;118

   Insert

   Kcnq3 (KCNQ3 Human)
   

   Use

   AAV

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   R230 to C230

   Promoter

   CMV

   Available Since

   Jan. 3, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pcDNA4/HisMaxB-YAP1-S127A

    Plasmid

    #18988

    Depositor

    Marius Sudol

    Article

    Oka et al J Biol Chem. 2008 Oct 10;283(41):27534-2

    Insert

    Yes-kinase associated protein S127A mutant (YAP1 Human)
    

    Tags

    His

    Expression

    Mammalian

    Mutation

    Serine 127 changed to Alanine, mutated protein t…

    Available Since

    Sept. 8, 2008

    Availability

    Academic Institutions and Nonprofits only

11. pAAV-FLEX-SaCas9-U6-sgGria1

    Plasmid

    #124853

    Purpose

    Mutagenesis of Gria1

    Depositor

    Larry Zweifel

    Article

    Hunker et al Cell Rep. 2020 Mar 24;30(12):4303-4316.e

    Insert

    Gria1 (Gria1 Mouse)
    

    Use

    AAV, CRISPR, and Mouse Targeting

    Available Since

    May 6, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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12. pLPC-Progerin

    Plasmid

    #69061

    Purpose

    encodes the lamin A mutant with a 50 amino acids deletion responsible for the Hutchinson-Gilford Progeria Syndrome

    Depositor

    Gerardo Ferbeyre

    Article

    Moiseeva et al Cell Cycle. 2015 Aug 3;14(15):2408-21. d

    Insert

    Progerin (LMNA Human)
    

    Use

    Retroviral

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Dec. 15, 2015

    Availability

    Academic Institutions and Nonprofits only

13. pGL4.0-TERT G228A

    Plasmid

    #84926

    Purpose

    luciferase reporter for mutant TERT promoter

    Depositor

    Joseph Costello

    Article

    Bell et al Science. 2015 May 29;348(6238):1036-9. d

    Insert

    TERT promoter (TERT Human)
    

    Use

    Luciferase

    Tags

    luciferase

    Expression

    Mammalian

    Mutation

    G228A

    Promoter

    TERT

    Available Since

    March 8, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pDEST53-LRRK2-R1441C

    Plasmid

    #25046

    Depositor

    Mark Cookson

    Article

    Greggio et al Neurobiol Dis. 2006 Aug . 23(2):329-41.

    Insert

    LRRK2 (LRRK2 Human)
    

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    Arginine 1441 mutated to Cysteine

    Available Since

    June 17, 2010

    Availability

    Academic Institutions and Nonprofits only

15. ATG-2460

    Plasmid

    #108713

    Purpose

    EF1-CBR2opt-T2A-copGFP (construct used for lentiviral transduction)

    Depositor

    Keith Wood

    Article

    Hall et al Nat Commun. 2018 Jan 9;9(1):132. doi: 10

    Insert

    CBR2opt-copGFP fusion
    

    Use

    Lentiviral

    Tags

    CBR2opt fused to copGFP

    Mutation

    Promega used directed evolution to create CBR (Cl…

    Promoter

    elongation factor-1

    Available Since

    Oct. 9, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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16. pGL4.0-TERT G250A

    Plasmid

    #84925

    Purpose

    luciferase reporter for mutant TERT promoter

    Depositor

    Joseph Costello

    Article

    Bell et al Science. 2015 May 29;348(6238):1036-9. d

    Insert

    TERT promoter (TERT Human)
    

    Use

    Luciferase

    Tags

    luciferase

    Expression

    Mammalian

    Mutation

    G250A

    Promoter

    TERT

    Available Since

    March 8, 2017

    Availability

    Academic Institutions and Nonprofits only

17. pF150 pSOD1G93AAcGFP1

    Plasmid

    #26411

    Purpose

    contains G94A mutation in pSOD1

    Depositor

    Elizabeth Fisher

    Article

    Stevens et al PLoS One. 2010 . 5(3):e9541.

    Insert

    SOD1 (SOD1 Human)
    

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    G94A

    Available Since

    Nov. 8, 2010

    Availability

    Academic Institutions and Nonprofits only

    

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18. pMYH9-D1424H-FLAG

    Plasmid

    #183513

    Purpose

    Gateway expression vector encoding D1424H mutant MYH9 cDNA, with N-terminal Flag tag. For mammalian expression.

    Depositor

    Emanuele Panza

    Article

    Panza et al Pathogenetics. 2008 Dec 1;1(1):5. doi: 1

    Insert

    MYH9 (MYH9 Human)
    

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    changed Aspartic acid 1424 to Histidine

    Promoter

    CMV

    Available Since

    May 17, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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19. pcDNA6 asyn A30P

    Plasmid

    #105729

    Purpose

    Mammalian expression of mutant human alpha synuclein

    Depositor

    Hilal Lashuel

    Article

    Mbefo et al J Biol Chem. 2015 Apr 10;290(15):9412-27

    Insert

    alpha-synuclein A30P (SNCA Human)
    

    Expression

    Mammalian

    Mutation

    A30P

    Promoter

    CMV

    Available Since

    March 29, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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20. EGFR D770-N771 insNPG

    Plasmid

    #11016

    Purpose

    Retroviral construct for expressing human EGFR with D770-N771 insNPG mutation in human cells

    Depositor

    Matthew Meyerson

    Article

    Greulich et al PLoS Med. 2005 Oct 4. 2(11):e313.

    Insert

    EGFR D770-N771 insNPG (EGFR Human)
    

    Use

    Retroviral

    Expression

    Mammalian

    Mutation

    D770-N771 insNPG

    Available Since

    Dec. 2, 2005

    Availability

    Academic Institutions and Nonprofits only