We narrowed to 18,340 results for: Mut

1. pAAV-SEPT_Cdk2-T160E-siR

   Plasmid

   #73976

   Purpose

   HDR template to generate Cdk2-T160E-siR

   Depositor

   Steven Dowdy, Manuel Kaulich

   Article

   Kaulich et al Nucleic Acids Res. 2015 Apr 20;43(7):e45

   Inserts

   Cdk2-LHA-siR (CDK2 Human)
   Cdk2-RHA-T160E (CDK2 Human)
   

   Use

   AAV

   Tags

   Expression

   Mutation

   T160 mutated to Glu and siRNA target site mutated

   Promoter

   Available Since

   March 18, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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2. pGL3E-hGPR56 e1m promoter perisylvian polymicrogyria

   Plasmid

   #52299

   Purpose

   Reporter for mutated human GPR56 exon 1m promoter activity. It contains a 15-bp deletion in a conserved noncoding element. The mutated human GPR56 e1m promoter was inserted into pGL3E.

   Depositor

   Christopher A Walsh

   Article

   Bae et al Science. 2014 Feb 14;343(6172):764-8. do

   Insert

   ADGRG1 adhesion G protein-coupled receptor G1 (ADGRG1 Human)
   

   Use

   Luciferase

   Tags

   Expression

   Mutation

   15-bp deletion in the promoter

   Promoter

   Human GPR56 e1m promoter

   Available Since

   April 15, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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3. pCMV CHMP2B-L4D,F5D-M85E-3XHA

   Plasmid

   #242416

   Purpose

   Expression of a CHMP2B membrane binding mutant (L4D F5D) with a M85E mutation and a 3xHA tag.

   Depositor

   Franz-Ulrich Hartl

   Article

   Sitron et al Mol Cell. 2025 Sep 18;85(18):3505-3523.e

   Insert

   CHMP2B (CHMP2B Human)
   

   Use

   Tags

   3xHA

   Expression

   Mammalian

   Mutation

   L4D F5D M85E

   Promoter

   CMV

   Available Since

   Sept. 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pCMV CHMP2B-L4D,F5D-V82E M85E M92E-3XHA

   Plasmid

   #242418

   Purpose

   Expression of a CHMP2B membrane binding mutant (L4D F5D) with V82E, M85E, and M92E mutations and a 3xHA tag.

   Depositor

   Franz-Ulrich Hartl

   Article

   Sitron et al Mol Cell. 2025 Sep 18;85(18):3505-3523.e

   Insert

   CHMP2B (CHMP2B Human)
   

   Use

   Tags

   3xHA

   Expression

   Mammalian

   Mutation

   L4D F5D V82E M85E M92E

   Promoter

   CMV

   Available Since

   Sept. 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pCMV CHMP2B-L4D,F5D-V82E-3XHA

   Plasmid

   #242393

   Purpose

   Expression of a CHMP2B membrane binding mutant (L4D F5D) with a V82E mutation and a 3xHA tag.

   Depositor

   Franz-Ulrich Hartl

   Article

   Sitron et al Mol Cell. 2025 Sep 18;85(18):3505-3523.e

   Insert

   CHMP2B (CHMP2B Human)
   

   Use

   Tags

   3xHA

   Expression

   Mammalian

   Mutation

   L4D F5D V82E

   Promoter

   CMV

   Available Since

   Sept. 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pCMV CHMP2B-L4D,F5D-M92E-3XHA

   Plasmid

   #242417

   Purpose

   Expression of a CHMP2B membrane binding mutant (L4D F5D) with a M92E mutation and a 3xHA tag.

   Depositor

   Franz-Ulrich Hartl

   Article

   Sitron et al Mol Cell. 2025 Sep 18;85(18):3505-3523.e

   Insert

   CHMP2B (CHMP2B Human)
   

   Use

   Tags

   3xHA

   Expression

   Mammalian

   Mutation

   L4D F5D M92E

   Promoter

   CMV

   Available Since

   Sept. 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pLenti-mEtfdh-AAA6

   Plasmid

   #232317

   Purpose

   Expression of mouse mutant Etfdh (AAA6)

   Depositor

   Ivan Topisirovic

   Article

   Papadopoli et al bioRxiv 2024.10.25.620155

   Insert

   Etfdh (Etfdh Mouse)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   PAM Sequence Mutations: (G36C; T39C, C42T; C72T, …

   Promoter

   Available Since

   Aug. 19, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pLenti-mEtfdh-AAG6

   Plasmid

   #232315

   Purpose

   Expression of mouse mutant Etfdh (AAG6)

   Depositor

   Ivan Topisirovic

   Article

   Papadopoli et al bioRxiv 2024.10.25.620155

   Insert

   Etfdh (Etfdh Mouse)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   PAM Sequence Mutations: (G36C, T39C, C42T, C72T, …

   Promoter

   Available Since

   Aug. 19, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. MSCV-KRAS-WT-IRES-mCherry

   Plasmid

   #221019

   Purpose

   Fluorescent reporter for expressing the KRAS wildtype CDS

   Depositor

   Mohamed Fareh

   Article

   Shembrey et al Sci Adv. 2024 Dec 20;10(51):eadl0731. do

   Insert

   KRAS wildtype (KRAS Human)
   

   Use

   Retroviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   Aug. 13, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pLV[Exp]-Bsd-CMV>hCDK11A

    Plasmid

    #239212

    Purpose

    Expresses CDK11A in mammalian cell lines

    Depositor

    Jason Sheltzer

    Article

    Julian et al bioRxiv 2025.08.03.668359; doi: https://

    Insert

    cyclin dependent kinase 11A (CDK11A Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Aug. 5, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pLenti-mEtfdh-AAA4

    Plasmid

    #232316

    Purpose

    Expression of mouse mutant Etfdh (AAA4)

    Depositor

    Ivan Topisirovic

    Article

    Papadopoli et al bioRxiv 2024.10.25.620155

    Insert

    Etfdh (Etfdh Mouse)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    PAM Sequence Mutations: (G36C; T39C, C42T; C72T, …

    Promoter

    Available Since

    March 26, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. Cdk13_intron3_sg4_pX458

    Plasmid

    #127339

    Purpose

    sgRNA that cuts within intron 3 of mouse CDK13 genomic locus- guide #4

    Depositor

    Phil Sharp

    Article

    Insco et al Science. 2023 Apr 21;380(6642):eabn7625.

    Insert

    Mouse Cdk13 Intron 3 sgRNA (Cdk13 Mouse)
    

    Use

    CRISPR and Mouse Targeting

    Tags

    Expression

    Mutation

    Promoter

    U6 Promoter

    Available Since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. Cdk13_intron4_sg3_pX330

    Plasmid

    #127340

    Purpose

    sgRNA that cuts within intron 4 of mouse CDK13 genomic locus- guide #3

    Depositor

    Phil Sharp

    Article

    Insco et al Science. 2023 Apr 21;380(6642):eabn7625.

    Insert

    Mouse Cdk13 Intron 4 Targeting sgRNA (Cdk13 Mouse)
    

    Use

    CRISPR and Mouse Targeting

    Tags

    Expression

    Mutation

    Promoter

    U6 Promoter

    Available Since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pCR8/GW_TOPO_Cdk13_Untagged

    Plasmid

    #127342

    Purpose

    Untagged mouse Cdk13 transgene (NP_001074527.1 isoform) cloned into Gateway entry vector

    Depositor

    Phil Sharp

    Article

    Insco et al Science. 2023 Apr 21;380(6642):eabn7625.

    Insert

    Cyclin Dependent Kinase 13 (Cdk13 Mouse)
    

    Use

    Entry vector with transgene for gateway cloning

    Tags

    Expression

    Mutation

    Base pairs 1-1554 of transgene are codon optimize…

    Promoter

    None

    Available Since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pTRE3G-mouse cGASdeltaN-GFP

    Plasmid

    #186878

    Purpose

    Doxycycline-dependent expression of mouse cGAS gene in mammalian cells by retroviral transduction

    Depositor

    Jonathan Kagan

    Article

    Mosallanejad et al Sci Immunol. 2023 Jan 20;8(79):eabp9765.

    Insert

    Mouse cGAS truncation mutant (148-508 a.a.) with C-terminal GFP fusion (Cgas Mouse, Synthetic)
    

    Use

    Retroviral

    Tags

    GFP

    Expression

    Mutation

    N-terminal truncation

    Promoter

    TRE3G

    Available Since

    Oct. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pTRE3G-human cGASdeltaN C396/397A-HA

    Plasmid

    #186850

    Purpose

    Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction

    Depositor

    Jonathan Kagan

    Article

    Mosallanejad et al Sci Immunol. 2023 Jan 20;8(79):eabp9765.

    Insert

    Human cGAS truncation mutant (160-522 a.a.) with DNA binding mutantation C396/397A) and C-terminal HA tag (Adamts1 Human, Synthetic)
    

    Use

    Retroviral

    Tags

    HA

    Expression

    Mutation

    N-terminal truncation, C396A, C397A

    Promoter

    TRE3G

    Available Since

    Oct. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. macroH2A2-V192F-GFP (pc5116)

    Plasmid

    #223439

    Purpose

    Mutation of valine 192 to phenylalanine (V192F) in macroH2A2.

    Depositor

    Cristina Cardoso

    Article

    Arroyo et al Nucleic Acids Res. 2024 Aug 27:gkae734.

    Insert

    macroH2A2-F192V (MACROH2A2, H2AFY2 Human)
    

    Use

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    Mutation of valine 192 to phenylalanine (V192F)

    Promoter

    CMV

    Available Since

    Oct. 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. pInducer-myc-ERK1-S170D

    Plasmid

    #213592

    Purpose

    Doxycycline inducible expression of myc-tagged ERK1-S170D cDNA in mammilian cells

    Depositor

    Channing Der

    Article

    Klomp et al Science. 2024 Jun 7;384(6700):eadk0850.

    Insert

    MAPK3 (MAPK3 Human)
    

    Use

    Lentiviral

    Tags

    MYC

    Expression

    Mammalian

    Mutation

    S170D

    Promoter

    Available Since

    Aug. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. pInducer-myc-ERK1-R84S/D338N

    Plasmid

    #213594

    Purpose

    Doxycycline inducible expression of myc-tagged ERK1-R84S/D338N cDNA in mammilian cells

    Depositor

    Channing Der

    Article

    Klomp et al Science. 2024 Jun 7;384(6700):eadk0850.

    Insert

    MAPK3 (MAPK3 Human)
    

    Use

    Lentiviral

    Tags

    MYC

    Expression

    Mammalian

    Mutation

    R84S, D338N

    Promoter

    Available Since

    Aug. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. pMXS-IRES-BLAST flag-CAD T456A S1406A S1859A

    Plasmid

    #169826

    Purpose

    Expresses C-terminal flag-tagged CAD with mutation of reported S6K, PKA, and Erk1/2 phosphorylation site

    Depositor

    Richard Possemato

    Article

    Shin et al Nat Metab. 2023 Feb 6. doi: 10.1038/s422

    Insert

    CAD (CAD Human)
    

    Use

    Retroviral

    Tags

    Flag tag

    Expression

    Mammalian

    Mutation

    T456A S1406A S1859A; TCCC -> AGTC silent mutat…

    Promoter

    Available Since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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