We narrowed to 133,566 results for: Mal

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Liu Lab MusCK Library B

Pooled Library

#174197

Purpose

MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK M_b contains 5 gRNAs per gene.

Depositor

Xiaole Shirley Liu

Article

Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available Since

Oct. 29, 2021

Availability

Academic Institutions and Nonprofits only
CHyMErA Large-Scale Exon Deletion hgRNA Library

Pooled Library

#209736

Purpose

CHyMErA Exon Deletion hgRNA Library allows identification of frame-preserving exons that affect cell fitness in human cells using the CHyMErA screening platform.

Depositor

Thomas Gonatopoulos-Pournatzis

Article

Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

June 20, 2024

Availability

Academic Institutions and Nonprofits only
EGFP miSFIT Lineage Barcoding Library

Pooled Library

#229136

Purpose

The EGFP_miSFIT_Lineage_BC_lib library is a transcribed lineage barcoding vector library.

Depositor

Peter Zandstra

Article

Michaels et al Cell Syst. 2024 Dec 18;15(12):1245-1263.

Expression

Mammalian

Use

Lentiviral

Available Since

Oct. 24, 2025

Availability

Academic Institutions and Nonprofits only
HR700_TP53Exon5mut

Pooled Library

#229137

Purpose

Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 5 of human cells via CRISPR-HDR.

Depositor

Thorsten Stiewe

Article

Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Cre/Lox

Available Since

Feb. 24, 2025

Availability

Industry, Academic Institutions, and Nonprofits
HR700_TP53Exon6mut

Pooled Library

#229138

Purpose

Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 6 of human cells via CRISPR-HDR.

Depositor

Thorsten Stiewe

Article

Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Cre/Lox

Available Since

Feb. 24, 2025

Availability

Industry, Academic Institutions, and Nonprofits
HR700_TP53Exon7mut

Pooled Library

#229139

Purpose

Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 7 of human cells via CRISPR-HDR.

Depositor

Thorsten Stiewe

Article

Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Cre/Lox

Available Since

Feb. 24, 2025

Availability

Industry, Academic Institutions, and Nonprofits
HR700_TP53Exon8mut

Pooled Library

#229140

Purpose

Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 8 of human cells via CRISPR-HDR.

Depositor

Thorsten Stiewe

Article

Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Cre/Lox

Available Since

Feb. 24, 2025

Availability

Industry, Academic Institutions, and Nonprofits
ALL-PAM sensor Library

Pooled Library

#179219

Purpose

10 human and mouse sgRNAs each where for each sgRNA the tethered target site has 1 of 64 possible 3 bp PAM sequences.

Depositor

Lukas Dow

Article

Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

Expression

Mammalian

Use

Lentiviral

Available Since

June 16, 2022

Availability

Academic Institutions and Nonprofits only
eeBxb1

Plasmid

#222339

Purpose

Plasmid for expressing evolved and engineered Bxb1 in the mammalian cells

Depositor

David Liu

Article

Pandey et al Nat Biomed Eng. 2024 Jun 10. doi: 10.103

Insert

Codon-optimized evolved and engineered Bxb1

Use

CRISPR

Expression

Mammalian

Promoter

CMV

Available Since

June 27, 2024

Availability

Academic Institutions and Nonprofits only

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pEGFP-LC3

Plasmid

#21073

Purpose

Mammalian expression of rat LC3 fused to EGFP

Depositor

Tamotsu Yoshimori

Article

Kabeya et al EMBO J. 2000 Nov 1. 19(21):5720-8.

Insert

microtubule-associated protein 1 light chain 3 beta (Map1lc3b Rat)

Tags

EGFP

Expression

Mammalian

Mutation

First ATG is not included.

Promoter

CMV

Available Since

May 11, 2009

Availability

Academic Institutions and Nonprofits only

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MLF2-GFP-3xFLAG

Plasmid

#230986

Purpose

Expresses GFP tagged MLF2 in mammalian cells

Depositor

Christian Schlieker

Article

Prophet et al Nat Cell Biol. 2022 Nov;24(11):1630-1641

Insert

MLF2 (MLF2 Human)

Tags

3xFLAG and GFP

Expression

Mammalian

Promoter

T7

Available Since

Jan. 6, 2025

Availability

Academic Institutions and Nonprofits only

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pRK5-HA-Ubiquitin-K48R

Plasmid

#17604

Purpose

Mammalian expression of HA tagged ubiquitin K48R

Depositor

Ted Dawson

Article

Lim et al J Neurosci. 2005 Feb 23. 25(8):2002-9.

Insert

Ubiquitin C (UBC Human)

Tags

HA

Expression

Mammalian

Mutation

K48R (expected to disrupt G76-K48 ubiquitin chain…

Available Since

March 31, 2008

Availability

Academic Institutions and Nonprofits only

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pEGFP-hGal3

Plasmid

#73080

Purpose

Expression in mammalian cells

Depositor

Tamotsu Yoshimori

Article

Maejima et al EMBO J. 2013 Aug 28;32(17):2336-47. doi:

Insert

Galectin-3 (LGALS3 Human)

Tags

EGFP

Expression

Mammalian

Promoter

CMV

Available Since

Feb. 11, 2016

Availability

Academic Institutions and Nonprofits only

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TurboID-CRaf

Plasmid

#226168

Purpose

Lentiviral plasmid used to express a TurboID fusion of the protein kinase CRaf.

Depositor

Dustin Maly

Article

Simon et al Nat Methods. 2024 Nov;21(11):2094-2106.

Insert

Myc-TurboID-CRaf (RAF1 Human)

Use

Lentiviral

Tags

EGFP-IRES-BlastR and Myc-TurboID

Expression

Mammalian

Available Since

Nov. 12, 2024

Availability

Academic Institutions and Nonprofits only

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pAAV-CKIIa-stGtACR2-FusionRed

Plasmid

#105669

Purpose

Expresses a soma-targeted GtACR2 in mammalian neurons under the CaMKIIa promoter

Depositor

Ofer Yizhar

Article

Mahn et al Nat Commun. 2018 Oct 8;9(1):4125. doi: 1

Has Service

AAV Retrograde and AAV1

Insert

stGtACR2

Use

AAV

Tags

FusionRed and Kv2.1

Expression

Mammalian

Promoter

CaMKIIa

Available Since

Feb. 23, 2018

Availability

Academic Institutions and Nonprofits only

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pcDNA 3.1(Hygro) myc-hPolQ-Flag

Plasmid

#73132

Purpose

To express in mammalian cells human PolQ

Depositor

Agnel Sfeir

Article

Mateos-Gomez et al Nature. 2015 Feb 12;518(7538):254-7. doi

Insert

Polymerase theta (POLQ Human)

Tags

Flag and myc

Expression

Mammalian

Promoter

cmv promoter

Available Since

March 11, 2016

Availability

Academic Institutions and Nonprofits only

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pCAG-SpCas9-GFP-U6-gRNA

Plasmid

#79144

Purpose

All-in-one CRISPR/Cas9 vector with CAG promoter for expression in human ESC/iPSC

Depositor

Jizhong Zou

Article

Stoehr et al JCI Insight. 2019 May 21;5. pii: 128496.

Insert

SpCas9

Use

CRISPR

Tags

2A-GFP

Expression

Mammalian

Promoter

CAG

Available Since

June 29, 2016

Availability

Academic Institutions and Nonprofits only

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PX458 V3

Plasmid

#226957

Purpose

CBh-SpCas9-2A-GFP, and hU6-sgRNA (Sp) with a BbsI golden gate cloning backbone for sgRNA. sgRNA uses 3TC scaffold for increased sgRNA expression.

Depositor

Paul Thomas

Article

Chey et al BMC Genomics. 2025 Feb 12;26(1):138. doi

Type

Empty backbone

Use

CRISPR

Expression

Mammalian

Available Since

Oct. 30, 2024

Availability

Academic Institutions and Nonprofits only

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pAAV_CaMKII-TRPV1-flag

Plasmid

#238924

Purpose

Expression of the human TRPV1 channel with a Flag-tag in excitatory neurons

Depositor

Vsevolod Belousov

Article

Maltsev et al Cell Mol Life Sci. 2024 Oct 25;81(1):437

Insert

CaMKII-TRPV1-flag

Use

AAV

Tags

flag

Expression

Mammalian

Promoter

CaMKIIalfa

Available Since

Aug. 19, 2025

Availability

Academic Institutions and Nonprofits only

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pRK5-HA-Ubiquitin-K33

Plasmid

#17607

Purpose

Mammalian expression of HA tagged ubiquitin with K33 only, other lysines mutated to arginines

Depositor

Ted Dawson

Article

Lim et al J Neurosci. 2005 Feb 23. 25(8):2002-9.

Insert

Ubiquitin C (UBC Human)

Tags

HA

Expression

Mammalian

Mutation

K33 only, other lysines mutated to arginines; P19…

Available Since

March 31, 2008

Availability

Academic Institutions and Nonprofits only

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