We narrowed to 3,871 results for: SPL

1. pCMS-dsRed2-C1824U LMNA-GFP minigene

   Plasmid

   #128231

   Purpose

   C1824U mutation Lamin A splicing reporter

   Depositor

   Tom Misteli

   Article

   Shilo et al Nucleic Acids Res. 2019 Apr 22. pii: 547

   Insert

   lamin A (LMNA Human)
   

   Use

   Tags

   GFP and SV40-driven dsRed2 to identify transfecte…

   Expression

   Mammalian

   Mutation

   C1824U

   Promoter

   CMV

   Available since

   Aug. 15, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pAAV-TNT4-Zfr-P2A-HA-luciferase-3xMIR122

   Plasmid

   #223184

   Purpose

   Plasmid containing the Zfr/Firefly luciferase/3xMIR122 cassette. Translation of luciferase is controlled by splicing modulation of the Zfr specifically in cardiomyocytes by risdiplam in vivo.

   Depositor

   Yuxuan Guo

   Article

   Chen et al Nat Cardiovasc Res. 2025 Jun 13. doi: 10

   Inserts

   luciferase (LOC116160065 firefly)
   mir122 (Mir122 Mouse)
   

   Use

   AAV

   Tags

   HA and engineered P2A

   Expression

   Mutation

   Promoter

   TNNT2

   Available since

   June 18, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pAAV-TNT4-Zfr-P2A-HA-YAP5SA

   Plasmid

   #223189

   Purpose

   Plasmid containing the Zfr/YAP5SA cassette. Translation of YAP5SA is controlled by splicing modulation of the Zfr by risdiplam.

   Depositor

   Yuxuan Guo

   Article

   Chen et al Nat Cardiovasc Res. 2025 Jun 13. doi: 10

   Insert

   YAP5SA (Yap1 Mouse)
   

   Use

   AAV

   Tags

   HA and engineered P2A

   Expression

   Mutation

   S61A, S109A, S127A, S164A, S381A

   Promoter

   TNNT2

   Available since

   June 18, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. GFP Cav2.2 human HAgHA -minus exon 18a -LONG-Cterm in pcDNA3

   Plasmid

   #198914

   Purpose

   N-terminal GFP tagged, exofacial HAgHA tag in Domain II, does not contain exon 18a - Long form of alternatively spliced C-teminus, in pcDNA3 vector

   Depositor

   Annette Dolphin

   Article

   Dahimene et al Function (Oxf). 2023 Oct 19;5(1):zqad060

   Insert

   Cav2.2 (CACNA1B Human)
   

   Use

   Tags

   N-terminal GFP, internal double HA

   Expression

   Mammalian

   Mutation

   exon 18a deleted, exon 19 starts 3 nucleotides ea…

   Promoter

   CMV

   Available since

   April 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. GFP Cav2.2 human HAgHA-plus exon 18a - Short-Cterm - Arginine -in pcDNA3

   Plasmid

   #198915

   Purpose

   N-terminal GFP tagged, exofacial HAgHA tag in Domain II, contains exon 18a, Short form of alternatively spliced C-teminus, SNP rs2278973 variant Arginine, in pcDNA3 vector

   Depositor

   Annette Dolphin

   Article

   Dahimene et al Function (Oxf). 2023 Oct 19;5(1):zqad060

   Insert

   Cav2.2 (CACNA1B Human)
   

   Use

   Tags

   N-terminal GFP, internal double HA

   Expression

   Mammalian

   Mutation

   snp rs2278973 Arginine

   Promoter

   CMV

   Available since

   April 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. GFP Cav2.2 human HAgHA -plus exon 18a - LONG-Cterm in pcDNA3

   Plasmid

   #198451

   Purpose

   N-terminal GFP tagged, exofacial HAgHA tag in Domain II, contains exon 18a- Long form of alternatively spliced C-teminus, in pcDNA3 vector

   Depositor

   Annette Dolphin

   Article

   Dahimene et al Function (Oxf). 2023 Oct 19;5(1):zqad060

   Insert

   Cav2.2 (CACNA1B Human)
   

   Use

   Tags

   N-terminal GFP, internal double HA

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   April 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pIRES-mCerulean-FRB-Cdc42/N12-Cdc42/13C(Q61L)-FKBP-mVenus-CAAX

   Plasmid

   #214278

   Purpose

   Express split-Cdc42 fragments that are fused with CIDs and FPs

   Depositor

   Cliff Stains

   Article

   He et al Angew Chem Int Ed Engl. 2024 Jul 26:e202

   Inserts

   Split-Cdc42 fragments fused with CIDs and FPs (CDC42 Human)
   Split-Cdc42 fragments fused with CIDs and FPs (CDC42 Human)
   

   Use

   Tags

   mCerulean (on insert 1) and mVenus (on insert 2)

   Expression

   Mammalian

   Mutation

   Cdc42-Q61L

   Promoter

   CMV

   Available since

   July 29, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pAAV-TNT4-Zfr-P2A-HA-YAP5SA-3xMIR122

   Plasmid

   #223186

   Purpose

   Plasmid containing the Zfr/YAP5SA/3xMIR122 cassette. Translation of YAP5SA is controlled by splicing modulation of the Zfr specifically in cardiomyocytes by risdiplam in vivo.

   Depositor

   Yuxuan Guo

   Article

   Chen et al Nat Cardiovasc Res. 2025 Jun 13. doi: 10

   Inserts

   YAP5SA (Yap1 Mouse)
   mir122 (Mir122 Mouse)
   

   Use

   AAV

   Tags

   HA and engineered P2A

   Expression

   Mutation

   S61A, S109A, S127A, S164A, S381A

   Promoter

   TNNT2

   Available since

   June 18, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. GFP Cav2.2 human -HAgHA-minus exon 18a -Short-Cterm - Arg -in pcDNA3

   Plasmid

   #198916

   Purpose

   N-terminal GFP tagged, exofacial HAgHA tag in Domain II, does not contain exon 18a, Short form of alternatively spliced C-teminus, SNP rs2278973 variant Arginine, in pcDNA3 vector

   Depositor

   Annette Dolphin

   Article

   Dahimene et al Function (Oxf). 2023 Oct 19;5(1):zqad060

   Insert

   Cav2.2 (CACNA1B Human)
   

   Use

   Tags

   N-terminal GFP, internal double HA

   Expression

   Mammalian

   Mutation

   exon 18a deleted, exon 19 starts 3 nucleotides ea…

   Promoter

   CMV

   Available since

   April 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pIRES-mCerulean-FRB-Cdc42/N12-Cdc42/13C(T17N)-FKBP-mVenus-CAAX

    Plasmid

    #214279

    Purpose

    Express split-Cdc42 fragments that are fused with CIDs and FPs

    Depositor

    Cliff Stains

    Article

    He et al Angew Chem Int Ed Engl. 2024 Jul 26:e202

    Inserts

    Split-Cdc42 fragments fused with CIDs and FPs (CDC42 Human)
    Split-Cdc42 fragments fused with CIDs and FPs (CDC42 Human)
    

    Use

    Tags

    mCerulean (on insert 1) and mVenus (on insert 2)

    Expression

    Mammalian

    Mutation

    Cdc42-T17N

    Promoter

    CMV

    Available since

    July 29, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pIRES-mCerulean-FRB-Rac1/N12-Rac1/13C(Q61L)-FKBP-mVenus-CAAX

    Plasmid

    #214280

    Purpose

    Express split-Rac1 fragments that are fused with CIDs and FPs

    Depositor

    Cliff Stains

    Article

    He et al Angew Chem Int Ed Engl. 2024 Jul 26:e202

    Inserts

    Split-Rac1 fragments fused with CIDs and FPs (RAC1 Human)
    Split-Rac1 fragments fused with CIDs and FPs (RAC1 Human)
    

    Use

    Tags

    mCerulean (on insert 1) and mVenus (on insert 2)

    Expression

    Mammalian

    Mutation

    Rac1-Q61L

    Promoter

    CMV

    Available since

    July 29, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pIRES-mCerulean-FRB-Rac1/N12-Rac1/13C(T17N)-FKBP-mVenus-CAAX

    Plasmid

    #214281

    Purpose

    Express split-Rac1 fragments that are fused with CIDs and FPs

    Depositor

    Cliff Stains

    Article

    He et al Angew Chem Int Ed Engl. 2024 Jul 26:e202

    Inserts

    Split-Rac1 fragments fused with CIDs and FPs (RAC1 Human)
    Split-Rac1 fragments fused with CIDs and FPs (RAC1 Human)
    

    Use

    Tags

    mCerulean (N terminal on insert 1) and mVenus (on…

    Expression

    Mammalian

    Mutation

    Rac1-T17N

    Promoter

    CMV

    Available since

    July 29, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pIRES-mCerulean-FRB-RhoA/N12-RhoA/13C(T19N)-FKBP-mVenus-CAAX

    Plasmid

    #214283

    Purpose

    Express split-RhoA fragments that are fused with CIDs and FPs

    Depositor

    Cliff Stains

    Article

    He et al Angew Chem Int Ed Engl. 2024 Jul 26:e202

    Inserts

    Split-RhoA fragments fused with CIDs and FPs (RHOA Human)
    Split-RhoA fragments fused with CIDs and FPs (RHOA Human)
    

    Use

    Tags

    mCerulean (N terminal on insert 1) and mVenus (on…

    Expression

    Mammalian

    Mutation

    RhoA-T19N

    Promoter

    CMV

    Available since

    July 29, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pLenti NLuc398-G8NCRD IRES G8NCRD-CLuc394

    Plasmid

    #128386

    Purpose

    Expresses a split firefly luciferase reporter based on the N terminal carbohydrate recognition domain of human galectin 8, which concentrates inside endosomes following endosomal disruption

    Depositor

    Craig Duvall

    Article

    Kilchrist et al ACS Sens. 2020 Jun 23. doi: 10.1021/acss

    Inserts

    NLuc-3xGGGGS-Gal8-NCRD (LGALS8 Synthetic, Human)
    Gal8-NCRD-3xGGGGS-CLuc398 (LGALS8 Human)
    

    Use

    Lentiviral, Luciferase, and Synthetic Biology

    Tags

    C-terminal luc2 fragment and N-terminal luc2 frag…

    Expression

    Mammalian

    Mutation

    N terminal carbohydrate recognition domain fused …

    Promoter

    EF1A and IRES

    Available since

    Jan. 17, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pIRES-mCerulean-FRB-KRas/N12-KRas/13C(Q61L)-FKBP-mVenus-CAAX

    Plasmid

    #214284

    Purpose

    Express split-KRas fragments that are fused with CIDs and FPs

    Depositor

    Cliff Stains

    Article

    He et al Angew Chem Int Ed Engl. 2024 Jul 26:e202

    Inserts

    Split-KRas fragments fused with CIDs and FPs (KRAS Human)
    Split-KRas fragments fused with CIDs and FPs (KRAS Human)
    

    Use

    Tags

    mCerulean (on insert 1) and mVenus (on insert 2)

    Expression

    Mammalian

    Mutation

    KRas-Q61L

    Promoter

    CMV

    Available since

    July 29, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pIRES-mCerulean-FRB-KRas/N12-KRas/13C(S17N)-FKBP-mVenus-CAAX

    Plasmid

    #214285

    Purpose

    Express split-KRas fragments that are fused with CIDs and FPs

    Depositor

    Cliff Stains

    Article

    He et al Angew Chem Int Ed Engl. 2024 Jul 26:e202

    Inserts

    Split-KRas fragments fused with CIDs and FPs (KRAS Human)
    Split-KRas fragments fused with CIDs and FPs (KRAS Human)
    

    Use

    Tags

    mCerulean (N terminal on insert 1) and mVenus (on…

    Expression

    Mammalian

    Mutation

    KRas-S17N

    Promoter

    CMV

    Available since

    July 29, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pIRES-mCerulean-GID1-KRas/N12-KRas/13C(Q61L)-GAI1-92-mVenus-CAAX

    Plasmid

    #214286

    Purpose

    Express split-KRas fragments that are fused with CIDs and FPs

    Depositor

    Cliff Stains

    Article

    He et al Angew Chem Int Ed Engl. 2024 Jul 26:e202

    Inserts

    Split-KRas fragments fused with CIDs and FPs (KRAS Human)
    Split-KRas fragments fused with CIDs and FPs (KRAS Human)
    

    Use

    Tags

    mCerulean (N terminal on insert 1) and mVenus (on…

    Expression

    Mammalian

    Mutation

    KRas-Q61L

    Promoter

    CMV

    Available since

    July 29, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pIRES-mCerulean-GID1-KRas/N12-KRas/13C(S17N)-GAI1-92-mVenus-CAAX

    Plasmid

    #214287

    Purpose

    Express split-KRas fragments that are fused with CIDs and FPs

    Depositor

    Cliff Stains

    Article

    He et al Angew Chem Int Ed Engl. 2024 Jul 26:e202

    Inserts

    Split-KRas fragments fused with CIDs and FPs (KRAS Human)
    Split-KRas fragments fused with CIDs and FPs (KRAS Human)
    

    Use

    Tags

    mCerulean (on insert 1) and mVenus (on insert 2)

    Expression

    Mammalian

    Mutation

    KRas-S17N

    Promoter

    CMV

    Available since

    July 29, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. JM83

    Bacterial Strain

    #50348

    Purpose

    E.coli K-12 derivative

    Depositor

    Joachim Messing

    Article

    Messing et al Recombinant DNA Technical Bulletin, 1979

    Bacterial Resistance

    None

    Species

    Escherichia coli

    Available since

    Oct. 14, 2014

    Availability

    Academic Institutions and Nonprofits only

20. E. coli K-12 MG1655 RARE

    Bacterial Strain

    #61440

    Purpose

    This E. coli chassis displays reduced endogenous reduction of aromatic and aliphatic aldehydes

    Depositor

    Kristala Prather

    Article

    Kunjapur et al J Am Chem Soc. 2014 Aug 20;136(33):11644

    Bacterial Resistance

    None

    Available since

    Feb. 1, 2015

    Availability

    Academic Institutions and Nonprofits only