We narrowed to 10,749 results for: AGA

1. pCDH-3_Flag-YTHDF2-D-MUT (nonsense mutation of sgYTHDF2-1)

   Plasmid

   #232947

   Purpose

   Expresses the domain-mutant YTHDF2 with synonymous mutations for resistance against sgYTHDF2-1-mediated knockdown

   Depositor

   Jianjun Chen

   Article

   Chen et al Cell. 2024 Dec 12:S0092-8674(24)01324-2.

   Insert

   YTHDF2-D-MUT (YTHDF2 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   5 site mutation (Y418A+D422A+W432A+W486A+W491A), …

   Promoter

   Available since

   May 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pCDH-3_Flag-YTHDF2-m(6)A-MUT (nonsense mutation of sgYTHDF2-1)

   Plasmid

   #232946

   Purpose

   Expresses the m6A-binding-deficient mutant of YTHDF2 with synonymous mutations for resistance against sgYTHDF2-1-mediated knockdown

   Depositor

   Jianjun Chen

   Article

   Chen et al Cell. 2024 Dec 12:S0092-8674(24)01324-2.

   Insert

   YTHDF2-m(6)A-MUT (YTHDF2 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   2 site mutation (W432A+W486A), synonymous mutation

   Promoter

   Available since

   May 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. lentiCRISPRv2_RB1#2

   Plasmid

   #174151

   Purpose

   Lentiviral vector expressing Cas9 and a sgRNA against the human RB1 gene

   Depositor

   Julien Sage

   Article

   Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

   Insert

   RB1 (RB1 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   Sept. 10, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pORANGE Dlg4-GFP KI

   Plasmid

   #131477

   Purpose

   Endogenous tagging of PSD95: C-terminal (amino acid position: R721)

   Depositor

   Harold MacGillavry

   Article

   Willems et al PLoS Biol. 2020 Apr 10;18(4):e3000665. d

   Insert

   gRNA and GFP donor (Dlg4, Dlg4 Rat, Mouse)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6 and Cbh

   Available since

   Sept. 19, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pLKO.1.sh.beta-catenin.2279

   Plasmid

   #19762

   Depositor

   William Hahn

   Article

   Firestein et al Nature. 2008 Sep 25. 455(7212):547-51.

   Insert

   small hairpin RNA against beta-catenin (CTNNB1 Human)
   

   Use

   Lentiviral and RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   July 6, 2009

   Availability

   Academic Institutions and Nonprofits only

6. DBDmut-CA-RIT-NFAT1

   Plasmid

   #63669

   Purpose

   Constitutively active NFAT1 and also unable to interact with AP-1 with four point mutations in the DNA binding loop that abolish DNA binding

   Depositor

   Anjana Rao

   Article

   Martinez et al Immunity. 2015 Feb 6. pii: S1074-7613(15

   Insert

   NFAT1 (Nfatc2 Mouse)
   

   Use

   Retroviral

   Tags

   3x HA

   Expression

   Mammalian

   Mutation

   CA: PASSGSSASF mutated to PAAAGAAAAF, SPRTSPIMSP…

   Promoter

   Available since

   July 22, 2015

   Availability

   Academic Institutions and Nonprofits only

7. pLentiCRISPRv1-sgPHGDH-G5

   Plasmid

   #83913

   Purpose

   stable knockout

   Depositor

   David Sabatini

   Article

   Pacold et al Nat Chem Biol. 2016 Jun;12(6):452-8. doi

   Insert

   Phosphoglycerate dehydrogenase (PHGDH Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   Oct. 24, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. lentiCRISPRv2_AMBRA1#1

   Plasmid

   #174152

   Purpose

   Lentiviral vector expressing Cas9 and a sgRNA against the human AMBRA1 gene

   Depositor

   Julien Sage

   Article

   Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

   Insert

   AMBRA (AMBRA1 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   Sept. 10, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pKLV2-U6gRNA5(SMARCA4(43))-PGKpuro2ABFP-W

   Plasmid

   #200464

   Purpose

   Lentiviral vector expressing gRNA targeting human SMARCA4

   Depositor

   Kosuke Yusa

   Article

   Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

   Insert

   SMARCA4(43) (SMARCA4 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Jan. 17, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pX330-TP53-2

    Plasmid

    #121918

    Purpose

    Encodes sgRNA targeting exon 9 of TP53

    Depositor

    William Hahn

    Article

    Howard et al Cancer Res. 2019 Feb 12. pii: 0008-5472.

    Insert

    TP53 (TP53 Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    Feb. 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge