We narrowed to 2,556 results for: neurod

1. FXN gRNA (BRDN0001146360)

   Plasmid

   #77815

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human FXN

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   FXN (FXN Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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2. pHR-TBP(38Q)-IDR-mCherry-Cry2-NLS

   Plasmid

   #145269

   Purpose

   Mammalian Expression of Nuclear Opto TBP(38Q) IDR with SV40 NLS

   Depositor

   Denes Hnisz

   Article

   Basu et al Cell. 2020 May 28;181(5):1062-1079.e30.

   Insert

   TBP(38Q)-IDR (TBP Human)
   

   Expression

   Mammalian

   Available Since

   Sept. 23, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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3. A1-LCD+7R+12D

   Plasmid

   #178678

   Purpose

   Bacterial expression of N-terminally 6His tagged A1-LCD with seven Arg residues added, twelve Glu residues added (LCD: low-complexity domain, aa 186-320)

   Depositor

   Tanja Mittag

   Article

   Bremer et al Nat Chem. 2022 Feb;14(2):196-207. doi: 1

   Insert

   A1-LCD+7R+12D (HNRNPA1 Human)
   

   Tags

   6xHis

   Expression

   Bacterial

   Mutation

   seven Arg residues added, twelve Glu residues add…

   Available Since

   March 17, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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4. KIF5A-GFP-SspB

   Plasmid

   #214401

   Purpose

   Expresses fusion of Kinesin heavy chain 5A (1-572) with GFP and SspB (micro)

   Depositor

   Liting Duan

   Article

   Liu et al Proc Natl Acad Sci U S A. 2024 Apr 2;121

   Insert

   KIF5A-GFP-SspB (Kif5a Rat, Synthetic)
   

   Tags

   KIF5A-GFP-SspB

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   March 20, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. pOmnibac_ZZ_linker_ybbR_Tau

   Plasmid

   #159717

   Purpose

   Expresses tau in Sf9 cells with a ZZ affinity tag and a ybbR tag

   Depositor

   Ahmet Yildiz

   Article

   Ferro et al Science. 2022 Jan 21;375(6578):326-331.

   Insert

   Microtubule-associated protein tau (MAPT Human)
   

   Tags

   ZZ affinity tag, ybbR tag

   Expression

   Insect

   Available Since

   Jan. 21, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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6. APP-bio-His

   Plasmid

   #51643

   Purpose

   Expresses full-length Amyloid beta A4 protein precursor ectodomain in mammalian cells. C-terminal rat Cd4d3+4 tag, biotinylation sequence and His tag.

   Depositor

   Gavin Wright

   Article

   Sun et al Mol Cell Proteomics. 2015 Feb 23. pii: m

   Insert

   APP (APP Human)
   

   Tags

   His tag, enzymatic biotinylation sequence, and ra…

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Feb. 27, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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7. pBABE-α-Syn-nYFP

   Plasmid

   #92203

   Purpose

   Retroviral overexpression vector for α-Syn bimolecular fluorescence complementation (BiFC)

   Depositor

   Huda Zoghbi

   Article

   Rousseaux et al Elife. 2016 Oct 25;5. pii: e19809. doi:

   Insert

   SNCA (SNCA Human)
   

   Use

   Retroviral

   Tags

   YFP(1-155)

   Expression

   Mammalian

   Available Since

   Aug. 7, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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8. pUCIDT-attL1-Human ABeta-attR5

   Plasmid

   #160436

   Purpose

   Entry vector for cloning human Amyloid Beta(1-42) using 2-fragment gateway recombination

   Depositor

   Nicholas Tolwinski

   Article

   Kaur et al Bio Protoc. 2020 Dec 5;10(23):e3856. doi

   Insert

   Homo sapiens amyloid beta precursor protein (APP Human)
   

   Expression

   Bacterial

   Available Since

   Oct. 6, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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9. pDONR221-SLC1A3_STOP

   Plasmid

   #161055

   Purpose

   Gateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors. Contains a STOP codon at the end of the codon-optimized ORF sequence.

   Depositor

   Giulio Superti-Furga, RESOLUTE Consortium

   Article

   Superti-Furga et al Nat Rev Drug Discov. 2020 Jul;19(7):429-

   Insert

   SLC1A3 (SLC1A3 Human)
   

   Expression

   Mammalian

   Available Since

   June 21, 2021

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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10. pBS-I-Sce1-eno2:Tau-IRES-egfp

    Plasmid

    #112205

    Purpose

    Used to make transgenic zebrafish expressing human 4R/0N Tau under the neuronal eno2 promoter

    Depositor

    Edward Burton

    Article

    Bai et al Nucleic Acids Res. 2007;35(19):6501-16.

    Insert

    MAPT (MAPT Human)
    

    Use

    Zebrafish expression

    Tags

    eno2 exon 2 translational fusion, ires-egfp at c …

    Promoter

    eno2 from zebrafish

    Available Since

    Aug. 3, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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11. APP_pcDNA6.2/EmGFP-Bsd

    Plasmid

    #176954

    Purpose

    Mammalian expression vector encoding APP and EmGFP-Bsd

    Depositor

    Roger Reeves

    Article

    Moyer et al Dis Model Mech. 2023 Apr 1;16(4):dmm0497

    Insert

    APP (APP Human)
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    April 19, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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12. RP1B FUS 1-163 S12xQ

    Plasmid

    #127193

    Purpose

    Protein expression for affinity purification

    Depositor

    Nicolas Fawzi

    Article

    Murthy et al Nat Struct Mol Biol. 2019 Jul;26(7):637-

    Insert

    FUS 1-163 S12xQ (FUS Human)
    

    Tags

    hexahistidine

    Expression

    Bacterial

    Mutation

    S12xQ: S30Q, S44Q, S48Q, S53Q, S70Q, S84Q, S89Q, …

    Available Since

    June 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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13. EIF2B3

    Plasmid

    #172072

    Purpose

    In vitro transcription for rescue experiments

    Depositor

    Cheol-Hee Kim

    Article

    Lee et al Hum Mol Genet. 2021 Apr 27;30(5):331-342

    Insert

    EIF2B3 (EIF2B3 Human)
    

    Expression

    Mammalian

    Mutation

    WT

    Promoter

    CMV

    Available Since

    July 18, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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14. PINK1 gRNA (BRDN0001487057)

    Plasmid

    #78037

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human PINK1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    PINK1 (PINK1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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15. pDONR223_TBK1_WT

    Plasmid

    #82285

    Purpose

    Gateway Donor vector containing TBK1, part of the Target Accelerator Plasmid Collection.

    Depositor

    Jesse Boehm, David Root, William Hahn

    Article

    Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

    Insert

    TBK1 (TBK1 Human)
    

    Use

    Gateway entry vector

    Mutation

    N388D; K570Q

    Promoter

    None

    Available Since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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16. BPK1520-LRRK2-G2019S-ng

    Plasmid

    #180436

    Purpose

    Transiently expressing a nicking sgRNA to facilitate the introduction of LRRK2-G2019S mutation in PE3 approach

    Depositor

    Frank Soldner

    Article

    Li et al Elife. 2022 Sep 7;11:e79208. doi: 10.755

    Insert

    ncRNA targeting LRRK2-G2019S (LRRK2 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    Nov. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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17. pU6-pegRNA-SNCA-A53T

    Plasmid

    #181738

    Purpose

    Transiently expressing a pegRNA to introduce SNCA-A53T mutation in human cells

    Depositor

    Dirk Hockemeyer

    Article

    Li et al Elife. 2022 Sep 7;11:e79208. doi: 10.755

    Insert

    Prime editing pegRNA for SNCA-A53T (SNCA Synthetic)
    

    Use

    CRISPR

    Expression

    Mammalian

    Promoter

    Human U6

    Available Since

    Sept. 8, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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18. pBPK1520-SNCA-A53T-ng

    Plasmid

    #181739

    Purpose

    Transiently expressing a nicking sgRNA to facilitate the introduction of SNCA-A53T mutation in PE3 approach

    Depositor

    Dirk Hockemeyer

    Article

    Li et al Elife. 2022 Sep 7;11:e79208. doi: 10.755

    Insert

    Prime editing ngRNA for SNCA-A53T (SNCA Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Promoter

    Human U6

    Available Since

    Sept. 8, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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19. TFORF0449

    Plasmid

    #143027

    Purpose

    Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

    Depositor

    Feng Zhang

    Article

    Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

    Insert

    DNMT1 (DNMT1 Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    EF1a

    Available Since

    June 27, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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20. pSico Dnmt1

    Plasmid

    #12165

    Purpose

    Cre-regulated lentiviral shRNA vector. Cre addition causes EGFP to be recombined out of the construct, activating Dnmt1 shRNA expression.

    Depositor

    Tyler Jacks

    Article

    Ventura et al Proc Natl Acad Sci U S A. 2004 Jul 13. 1

    Insert

    Dnmt1 shRNA (Dnmt1 Mouse)
    

    Use

    Cre/Lox, Lentiviral, and RNAi

    Expression

    Mammalian

    Mutation

    EGFP is expressed from this plasmid as a marker, …

    Available Since

    June 30, 2006

    Availability

    Academic Institutions and Nonprofits only