We narrowed to 4,337 results for: U6 gRNA

1. pSIL-eGFP-shACTN3

   Plasmid

   #52678

   Purpose

   shRNA against α-actinin-3 with eGFP transfection marker

   Depositor

   Johannes Hell

   Article

   Schnizler et al J Biol Chem. 2009 Jan 30;284(5):2697-705

   Insert

   ACTN3 (Actn3 Rat)
   

   Use

   RNAi

   Tags

   CMV-EGFP

   Expression

   Mutation

   Promoter

   U6

   Available since

   June 10, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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2. pJZC42

   Plasmid

   #66564

   Purpose

   sgRNA + 1XPP7 with PCP-VP64 effector for mammalian cells, marked by mCherry

   Depositor

   Wendell Lim, Stanley Qi

   Article

   Zalatan et al Cell. 2014 Dec 18. pii: S0092-8674(14)01

   Inserts

   sgRNA + 1XPP7
   PCP-VP64 IRES mCherry
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   CMV and U6

   Available since

   July 6, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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3. pMKO.1 puro-luc (shRNA)

   Plasmid

   #153962

   Purpose

   Expresses a shRNA against firefly luciferase

   Depositor

   Hiroyuki Konishi

   Article

   Hyodo et al Cell Rep. 2020 Jan 28;30(4):1195-1207.e7

   Insert

   shRNA against firefly luciferase (19-bp-long target)
   

   Use

   Luciferase, RNAi, and Retroviral

   Tags

   N/A

   Expression

   Mammalian

   Mutation

   Promoter

   U6 promoter

   Available since

   July 21, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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4. pKS7107

   Plasmid

   #89051

   Purpose

   Expresses Nm crRNA, Nm tracrRNA and human codon-optimized NmCas9

   Depositor

   Ervin Welker

   Article

   Toth et al Biol Direct. 2016 Sep 14;11:46. doi: 10.

   Inserts

   Nm crRNA
   Nm tracrRNA
   hNmCas9
   

   Use

   CRISPR

   Tags

   HA tag, NLS, and SV40 NLS

   Expression

   Mutation

   Promoter

   EF1a and human U6

   Available since

   April 14, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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5. pLV-shGrm2-2344

   Plasmid

   #120725

   Purpose

   Lentiviral vector that expresses GFP and an shRNA targeting Grm2 (in pLL3.7)

   Depositor

   Amy Lasek

   Article

   Ding et al Alcohol Clin Exp Res. 2017 Nov;41(11):18

   Insert

   Grm2 (Grm2 Rat)
   

   Use

   Lentiviral and RNAi

   Tags

   GFP

   Expression

   Mammalian

   Mutation

   Promoter

   mouse U6

   Available since

   March 12, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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6. pLV-shGrm2-972

   Plasmid

   #120724

   Purpose

   Lentiviral vector that expresses GFP and an shRNA targeting Grm2 (in pLL3.7)

   Depositor

   Amy Lasek

   Article

   Ding et al Alcohol Clin Exp Res. 2017 Nov;41(11):18

   Insert

   Grm2 (Grm2 Rat)
   

   Use

   Lentiviral and RNAi

   Tags

   GFP

   Expression

   Mammalian

   Mutation

   Promoter

   mouse U6

   Available since

   March 12, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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7. pX459_HR_Prnp_3

   Plasmid

   #78623

   Purpose

   pX459 vector encoding SpCas9-2A-Puro and a chimeric guide RNA targeting Prnp coding sequence

   Depositor

   Walker Jackson

   Article

   Kaczmarczyk et al PLoS One. 2016 Apr 29;11(4):e0154604. do

   Insert

   HR_Prnp_3 (Prnp Mouse)
   

   Use

   CRISPR and Mouse Targeting

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   July 19, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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8. pSicoR-PTPN11i1

   Plasmid

   #59612

   Purpose

   Expression of shRNA against human PTPN11

   Depositor

   Miguel Ramalho-Santos

   Article

   Qin et al Cell. 2014 Jul 17;158(2):449-61. doi: 10

   Insert

   PTPN11 (PTPN11 Human)
   

   Use

   RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Sept. 29, 2014

   Availability

   Academic Institutions and Nonprofits only

9. pSicoR-PTPN11i2

   Plasmid

   #59613

   Purpose

   Expression of shRNA against human PTPN11

   Depositor

   Miguel Ramalho-Santos

   Article

   Qin et al Cell. 2014 Jul 17;158(2):449-61. doi: 10

   Insert

   PTPN11 (PTPN11 Human)
   

   Use

   RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Sept. 29, 2014

   Availability

   Academic Institutions and Nonprofits only

10. pLV.U6.gLacZ.Cas9-T2A-GFP

    Plasmid

    #170361

    Purpose

    Negative control plasmid used for Crispr/cas9 based disruption.

    Depositor

    Johan Jakobsson

    Article

    Jonsson et al Nat Commun. 2019 Jul 18;10(1):3182. doi:

    Insert

    Cas9-T2A-GFP
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    June 27, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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11. PMKO-shNC

    Plasmid

    #64863

    Purpose

    Expresses a scrambled shRNA

    Depositor

    Lei Sun

    Article

    Alvarez-Dominguez et al Cell Metab. 2015 May 5;21(5):764-76. doi

    Insert

    Scrambled shRNA
    

    Use

    Retroviral

    Tags

    Expression

    Mutation

    Promoter

    u6

    Available since

    May 26, 2015

    Availability

    Academic Institutions and Nonprofits only

12. pLL3.7-Casp2-shRNA

    Plasmid

    #157926

    Purpose

    Knockdown of caspase-2

    Depositor

    Baoji Xu

    Article

    Xu et al Nat Commun. 2019 Aug 9;10(1):3622. doi:

    Insert

    Casp2 shRNA (Casp2 Mouse)
    

    Use

    Lentiviral and RNAi

    Tags

    GFP

    Expression

    Mutation

    Promoter

    mouse U6

    Available since

    Sept. 10, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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13. pLentiCRISPR-v1-sgGPT2_9

    Plasmid

    #163456

    Purpose

    lentiviral vector expressing Cas9 and an sgRNA targeting GPT2

    Depositor

    Jason Cantor

    Article

    Rossiter et al Cell Metab. 2021 Feb 23. pii: S1550-4131

    Insert

    sgRNA 9 targeting GPT2 (GPT2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Jan. 26, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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14. Lenti_CRISPRi_sgNeg2

    Plasmid

    #166999

    Purpose

    Lentiviral expression of negative control sgRNA for CRISPRi knockdown

    Depositor

    Gian-Paolo Dotto

    Article

    Ma et al J Exp Med. 2021 Feb 1;218(2). pii: 21150

    Insert

    Negative control sgRNA 2
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    April 23, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pJZC40

    Plasmid

    #62334

    Purpose

    sgRNA + 2x PP7 with mCherry for mammalian cells

    Depositor

    Wendell Lim, Stanley Qi

    Article

    Zalatan et al Cell. 2014 Dec 18. pii: S0092-8674(14)01

    Inserts

    sgRNA + 2x PP7
    mCherry
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Targets Tet3G, sequence: GTACGTTCTCTATCACTGATA

    Promoter

    CMV and U6

    Available since

    May 12, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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16. pJZC39

    Plasmid

    #62333

    Purpose

    sgRNA + 1x PP7 with mCherry for mammalian cells

    Depositor

    Wendell Lim, Stanley Qi

    Article

    Zalatan et al Cell. 2014 Dec 18. pii: S0092-8674(14)01

    Inserts

    sgRNA + 1x PP7
    mCherry
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Targets Tet3G, sequence: GTACGTTCTCTATCACTGATA

    Promoter

    CMV and U6

    Available since

    April 2, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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17. pLKO-Cre sgAdam10 v3

    Plasmid

    #158034

    Purpose

    lenti-viral construct with Cre recombinase and U6 driven sgRNA against mouse Adam10

    Depositor

    Daniel Schramek

    Article

    Loganathan et al Science. 2020 Mar 13;367(6483):1264-1269

    Insert

    Adam10 sgRNA
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 5, 2020

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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18. pEcoCascade-IL1RNcrRNA

    Plasmid

    #126481

    Purpose

    Encodes E.coli CRISPR Type I-E crRNA targeting IL1RN

    Depositor

    Charles Gersbach

    Article

    Pickar-Oliver et al Nat Biotechnol. 2019 Sep 23. pii: 10.103

    Insert

    Eco IL1RN cr26
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Sept. 30, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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19. pEN_hU6miR-G13-L

    Plasmid

    #25758

    Purpose

    Entry vector with human U6 promoter driving mouse G alpha 13 miR30-based shRNA.

    Depositor

    Iain Fraser

    Article

    Shin et al Proc Natl Acad Sci U S A. 2006 Sep 12. 1

    Insert

    G alpha 13 miR-shRNA
    

    Use

    Entry vector

    Tags

    Expression

    Mutation

    Promoter

    Available since

    July 1, 2010

    Availability

    Academic Institutions and Nonprofits only

    

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20. pLentiCRISPR-v1-sgDHFR

    Plasmid

    #233898

    Purpose

    lentiviral vector expressing Cas9 and an sgRNA targeting DHFR

    Depositor

    Jason Cantor

    Article

    Flickinger et al Nat Metab. 2025 May 2. doi: 10.1038/s422

    Insert

    sgRNA targeting DHFR (DHFR Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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