We narrowed to 343 results for: TP53

1. pMX-53BP1(1-1710) 3LA7A

   Plasmid

   #185707

   Purpose

   Mammalian Expression, Retroviral vector that encodes 7A and 3LA mutant of 53BP1. Prevents shieldin and RIF1 recruitment to sites of double-strand breaks and disrupts 53BP1 activity.

   Depositor

   Daniel Durocher

   Article

   Setiaputra et al Mol Cell. 2022 Apr 7;82(7):1359-1371.e9.

   Insert

   53BP1(1-1710) 3LA7A (TP53BP1 Human)
   

   Use

   Retroviral

   Tags

   Flag tag, HA tag, and tetracysteine tag

   Expression

   Mammalian

   Mutation

   T302A, S452A, S523A, S543A, S625A, S784A, and S89…

   Promoter

   SV40

   Available since

   July 1, 2022

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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2. pDEST 3xFlag-pcDNA5-FRT/T0-53BP1 28A

   Plasmid

   #52505

   Purpose

   mammalian expression vector of 53BP1 28A mutant

   Depositor

   Daniel Durocher

   Article

   Escribano-Diaz et al Mol Cell. 2013 Mar 7;49(5):872-83. doi:

   Insert

   53BP1 28A (TP53BP1 Human)
   

   Use

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   All 28 SQ/TQ motifs in N-term of 53BP1 have been …

   Promoter

   Available since

   April 10, 2015

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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3. MIP 247 CoMiP 4in1 with shRNA p53

   Plasmid

   #63726

   Purpose

   To express Oct4, Klf4, Sox2, c-Myc and hairpin RNA p53. A single plasmid reprogramming system using a mini-intronic plasmid (MIP).

   Depositor

   Mark Kay, Joseph Wu

   Article

   Diecke et al Sci Rep. 2015 Jan 28;5:8081. doi: 10.103

   Insert

   Mini-intronic-plasmid intron (POU5F1, KLF4, SOX2, MYC, TP53 Human)
   

   Use

   Tags

   IRES-dtomato

   Expression

   Mammalian

   Mutation

   codon-optimised

   Promoter

   SFFV for Pct4, Klf4, Sox2 and c-myc; U6 for p53

   Available since

   Aug. 28, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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