We narrowed to 144 results for: Snca

1. pDONOR-SNCAe3-A53T

   Plasmid

   #85848

   Purpose

   Donor plasmid for SNCA exon3 A53T sequence. Also contains EGFP and tagBFP

   Depositor

   Jens Schwamborn

   Article

   Arias-Fuenzalida et al Stem Cell Reports. 2017 Nov 14;9(5):1423

   Insert

   SNCA exon 3 homology arms (SNCA Human)
   

   Use

   Tags

   Expression

   Bacterial and Mammalian

   Mutation

   Promoter

   Available Since

   May 30, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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2. 1a. pETM11-SUMO-SNCA-GFP

   Plasmid

   #107292

   Purpose

   Plasmid for the expression of the construct alpha-Synuclein-GFP, which contains N-terminal tags, which can be cleaved later: His-tag for purification and SUMO-tag for better solubility

   Depositor

   Dmytro Yushchenko

   Article

   Afitska et al Biophys J. 2017 Nov 21;113(10):2182-2191

   Insert

   SNCA-GFP (SNCA Human)
   

   Use

   Tags

   His-tag and SUMO-tag

   Expression

   Bacterial

   Mutation

   Promoter

   T7

   Available Since

   May 1, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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3. pU6-pegRNA-SNCA-A53T

   Plasmid

   #181738

   Purpose

   Transiently expressing a pegRNA to introduce SNCA-A53T mutation in human cells

   Depositor

   Dirk Hockemeyer

   Article

   Li et al Elife. 2022 Sep 7;11:e79208. doi: 10.755

   Insert

   Prime editing pegRNA for SNCA-A53T (SNCA Synthetic)
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Human U6

   Available Since

   Sept. 8, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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4. pU6-pegRNA-SNCA-A30P

   Plasmid

   #180016

   Purpose

   Transiently expressing a pegRNA to introduce SNCA-A30P mutation in human cells

   Depositor

   Dirk Hockemeyer

   Article

   Li et al Elife. 2022 Sep 7;11:e79208. doi: 10.755

   Insert

   Prime editing pegRNA for SNCA-A30P (SNCA Synthetic)
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Human U6

   Available Since

   Sept. 8, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. pCMV-SNCA-A53T-mClover3

   Plasmid

   #215378

   Purpose

   Expression of the A53T mutant of alpha-synuclein with a C-terminal mClover3 tag.

   Depositor

   Franz-Ulrich Hartl

   Article

   Sitron et al Mol Cell. 2025 Sep 18;85(18):3505-3523.e

   Insert

   SNCA (SNCA Human)
   

   Use

   Tags

   mClover3 tag

   Expression

   Mammalian

   Mutation

   Ala53Thr

   Promoter

   Available Since

   Aug. 22, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pCMV-SNCA-A53T-mRuby3

   Plasmid

   #215379

   Purpose

   Expression of the A53T mutant of alpha-synuclein with a C-terminal mRuby3 tag.

   Depositor

   Franz-Ulrich Hartl

   Article

   Sitron et al Mol Cell. 2025 Sep 18;85(18):3505-3523.e

   Insert

   SNCA (SNCA Human)
   

   Use

   Tags

   mRuby3 tag

   Expression

   Mammalian

   Mutation

   Ala53Thr

   Promoter

   Available Since

   Aug. 22, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. FUW-hSNCA(D2R)-GFP

   Plasmid

   #215490

   Purpose

   Lentiviral expression and easy visualization of mutated alpha-synuclein (2nd amino acid aspartate mutated to arginine) in mammalian cells

   Depositor

   Ophir Shalem

   Article

   Santhosh Kumar et al Sci Adv. 2024 Feb 9;10(6):eadj4767. doi:

   Insert

   alpha-synuclein (SNCA Human)
   

   Use

   Lentiviral

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   D (second aa) mutated to R

   Promoter

   Ubc

   Available Since

   April 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. FUW-hSNCA(D2E)-GFP

   Plasmid

   #215491

   Purpose

   Lentiviral expression and easy visualization of mutated alpha-synuclein (2nd amino acid aspartate mutated to glutamate) in mammalian cells

   Depositor

   Ophir Shalem

   Article

   Santhosh Kumar et al Sci Adv. 2024 Feb 9;10(6):eadj4767. doi:

   Insert

   alpha-synuclein (SNCA Human)
   

   Use

   Lentiviral

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   D (second aa) mutated to E

   Promoter

   Ubc

   Available Since

   April 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. pAAV-hSyn-GFP-IRES-hSNCA

   Plasmid

   #185715

   Purpose

   AAV expression of GFP and human α-Synuclein from hSyn promoter

   Depositor

   Jun Ding

   Article

   Albarran et al Nat Neurosci. 2023 Jun;26(6):997-1007. d

   Insert

   synuclein, alpha (SNCA Human)
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   hSyn

   Available Since

   June 28, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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10. pAAV-hSyn-GFP-IRES-mSNCA

    Plasmid

    #185714

    Purpose

    AAV expression of GFP and mouse α-Synuclein from hSyn promoter

    Depositor

    Jun Ding

    Article

    Albarran et al Nat Neurosci. 2023 Jun;26(6):997-1007. d

    Insert

    synuclein, alpha (Snca Mouse)
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    hSyn

    Available Since

    June 28, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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11. pcDNA_FRT_SNCA-Avi_HygR-2A-BirA.dna(TO_deleted). (pEHA1448)

    Plasmid

    #209083

    Purpose

    SNCA (Avi tagged) expression along with BirA ligase

    Depositor

    Vikram Khurana

    Article

    Hallacli et al Cell. 2022 Jun 9;185(12):2035-2056.e33.

    Inserts

    SNCA (SNCA Human)
    BirA
    

    Use

    Tags

    Avi

    Expression

    Mammalian

    Mutation

    human codon optimized

    Promoter

    CMV

    Available Since

    Oct. 27, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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12. pAAV-hSyn-GFP-IRES-mSNCA(1-95)

    Plasmid

    #185716

    Purpose

    AAV expression of GFP and C-terminal truncated (1-95 amino acid) mouse α-Synuclein from hSyn promoter

    Depositor

    Jun Ding

    Article

    Albarran et al Nat Neurosci. 2023 Jun;26(6):997-1007. d

    Insert

    synuclein, alpha (Snca Mouse)
    

    Use

    AAV

    Tags

    Expression

    Mutation

    deleted AA 95-144

    Promoter

    hSyn

    Available Since

    June 28, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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13. pAAV-hSyn-GFP-IRES-hSNCA (A30P)

    Plasmid

    #185720

    Purpose

    AAV expression of GFP and human α-Synuclein with A30P mutation from hSyn promoter

    Depositor

    Jun Ding

    Article

    Albarran et al Nat Neurosci. 2023 Jun;26(6):997-1007. d

    Insert

    synuclein, alpha (SNCA Human)
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Changed Ala 30 to Pro

    Promoter

    hSyn

    Available Since

    April 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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14. pAAV-Syn1-DIO-Snca (human A53T)

    Plasmid

    #214201

    Purpose

    For Cre-dependent expression of alpha synuclein (human gene containing A53T mutation)

    Depositor

    Thomas Hnasko

    Article

    Steinkellner et al Brain. 2022 Apr 29;145(3):879-886. doi:

    Insert

    Snca (A53T) (SNCA Human)
    

    Use

    AAV and Cre/Lox

    Tags

    Expression

    Mammalian

    Mutation

    A53T

    Promoter

    Available Since

    March 29, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. piggyBac_rtTA (4th_Gen)_SNCA_IRES_NGN2-2A-PURO_Synapsin-BirA (pEHA1623)

    Plasmid

    #209085

    Purpose

    Ngn2 mediated cortical neuron induction, SNCA(wt) expression, Synapsin promoter BirA ligase expression

    Depositor

    Vikram Khurana

    Article

    Hallacli et al Cell. 2022 Jun 9;185(12):2035-2056.e33.

    Inserts

    SNCA (SNCA Human)
    NGN2 (Neurog2 Mouse)
    BirA
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    human codon optimized

    Promoter

    TRE4G and hSyn

    Available Since

    Dec. 5, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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16. pAAV-hSyn-GFP-IRES-hSNCA (S129D)

    Plasmid

    #185719

    Purpose

    AAV expression of GFP and human α-Synuclein with S129D mutation from hSyn promoter

    Depositor

    Jun Ding

    Article

    Albarran et al Nat Neurosci. 2023 Jun;26(6):997-1007. d

    Insert

    synuclein, alpha (SNCA Human)
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Changed Ser 129 to Asp

    Promoter

    hSyn

    Available Since

    June 28, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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17. pAAV-hSyn-GFP-IRES-hSNCA (S129A)

    Plasmid

    #185718

    Purpose

    AAV expression of GFP and human α-Synuclein with S129A mutation from hSyn promoter

    Depositor

    Jun Ding

    Article

    Albarran et al Nat Neurosci. 2023 Jun;26(6):997-1007. d

    Insert

    synuclein, alpha (SNCA Human)
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Changed Ser 129 to Ala

    Promoter

    hSyn

    Available Since

    June 28, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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18. piggyBac_rtTA (4th_Gen)_SNCA-Avi_IRES_NGN2-2A-PURO_Synapsin-BirA (pEHA1628)

    Plasmid

    #209086

    Purpose

    Ngn2 mediated cortical neuron induction, SNCA(Avi tagged) expression, Synapsin promoter BirA ligase expression

    Depositor

    Vikram Khurana

    Article

    Hallacli et al Cell. 2022 Jun 9;185(12):2035-2056.e33.

    Inserts

    SNCA (SNCA Human)
    NGN2 (Neurog2 Mouse)
    BirA
    

    Use

    Tags

    AviTag

    Expression

    Mammalian

    Mutation

    human codon optimized

    Promoter

    TRE4G and hSyn

    Available Since

    Dec. 13, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pAAV-hSyn-GFP-IRES-hSNCA (A11P/V70P)

    Plasmid

    #185717

    Purpose

    AAV expression of GFP and human α-Synuclein with A11P and V70P mutations from hSyn promoter

    Depositor

    Jun Ding

    Article

    Albarran et al Nat Neurosci. 2023 Jun;26(6):997-1007. d

    Insert

    synuclein, alpha (SNCA Human)
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Changed Ala 11 to Pro, Val 70 to Pro

    Promoter

    hSyn

    Available Since

    June 28, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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20. piggyBac-rtTA (4th_Gen)-SNCA(3K)-sfGFP-IRES-NGN2-puro (VK_1120)

    Plasmid

    #209078

    Purpose

    Ngn2 mediated cortical neuron induction, along with SNCA(3K) over-expression

    Depositor

    Vikram Khurana

    Article

    Lam et al bioRxiv 2022.11.08.515615

    Inserts

    SNCA (SNCA Human)
    NGN2 (Neurog2 Mouse)
    

    Use

    Tags

    sfGFP

    Expression

    Mammalian

    Mutation

    3K mutant: E35K, E46K, E61K

    Promoter

    TRE4G

    Available Since

    Dec. 13, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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