We narrowed to 116 results for: Mdc1

1. pLenti-CMV-GSDMD-eGFP-SV40p-BlasR

   Plasmid

   #228254

   Purpose

   pLenti-CMV-GSDMD-eGFP-SV40p-BlasR plasmid for ectopic expression of human full-length GSDMD fusion with GFP

   Depositor

   Judy Lieberman

   Article

   Fontana et al Cell. 2024 Sep 2:S0092-8674(24)00898-5.

   Insert

   GSDMD (GSDMD Human)
   

   Use

   Lentiviral

   Tags

   eGFP

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pDB-His-MBP-mGSDMD

   Plasmid

   #123365

   Purpose

   Expression of full-length mouse GSDMD in E. coli

   Depositor

   Hao Wu

   Article

   Orning et al Science. 2018 Nov 30;362(6418):1064-1069

   Insert

   GSDMD (Gsdmd Mouse)
   

   Use

   Tags

   His6-MBP

   Expression

   Bacterial

   Mutation

   Promoter

   T7

   Available since

   May 3, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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3. pUBQ10::ZF1CACTA1_3xFLAG_TET1cd

   Plasmid

   #106434

   Purpose

   pUBQ10 driven Zinc Finger human TET1 catalytic domain fusion that targets the CACTA1 promoter in arabidopsis

   Depositor

   Steven Jacobsen

   Article

   Gallego-Bartolome et al Proc Natl Acad Sci U S A. 2018 Feb 27;11

   Insert

   TET1 tet methylcytosine dioxygenase 1 (TET1 Synthetic, Human)
   

   Use

   Synthetic Biology

   Tags

   3xFLAG

   Expression

   Plant

   Mutation

   Promoter

   Available since

   March 22, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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4. pUBQ10::ZF108_3xFLAG_TET1cd

   Plasmid

   #106432

   Purpose

   pUBQ10 driven Zinc Finger human TET1 catalytic domain fusion that targets the FWA promoter in arabidopsis

   Depositor

   Steven Jacobsen

   Article

   Gallego-Bartolome et al Proc Natl Acad Sci U S A. 2018 Feb 27;11

   Insert

   pUBQ10::ZF108_3xFLAG_TET1cd (TET1 Synthetic, Human, Mustard Weed)
   

   Use

   Synthetic Biology

   Tags

   Expression

   Plant

   Mutation

   Promoter

   Available since

   March 14, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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5. pUBQ10::ZF2CACTA1_3xFLAG_TET1cd

   Plasmid

   #106433

   Purpose

   pUBQ10 driven Zinc Finger human TET1 catalytic domain fusion that targets the CACTA1 promoter in arabidopsis

   Depositor

   Steven Jacobsen

   Article

   Gallego-Bartolome et al Proc Natl Acad Sci U S A. 2018 Feb 27;11

   Insert

   pUBQ10::ZF1CACTA1_3xFLAG_TET1cd (TET1 Synthetic, Human, Mustard Weed)
   

   Use

   Synthetic Biology

   Tags

   3xFLAG

   Expression

   Plant

   Mutation

   Promoter

   Available since

   March 22, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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6. pD649-HAsp-MDGA2-Fc(DAPA)-AviTag-6xHis

   Plasmid

   #157001

   Purpose

   Mammalian expression of cell-surface protein extracellular domain fused to Fc(DAPA)-Avi-6xHis. Protein is secreted from cells.

   Depositor

   Chris Garcia

   Article

   Wojtowicz et al Cell. 2020 Aug 20;182(4):1027-1043.e17.

   Insert

   MDGA2 (MDGA2 Human)
   

   Use

   Tags

   Fc(DAPA)-AviTag-6xHis

   Expression

   Mammalian

   Mutation

   Fc region of human IgG contains D265A and P329A m…

   Promoter

   CMV/SP6

   Available since

   March 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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7. pcDNA3.1-GSDMD_H270A

   Plasmid

   #224701

   Purpose

   Expression of mutated Gasdermin D_H270A (GSDMD_H270A) in transfected mammalian cell lines

   Depositor

   Christopher Overall

   Article

   Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

   Insert

   GSDMD_H270A (GSDMD Human)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   H270A

   Promoter

   CMV

   Available since

   July 2, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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8. pcDNA3.1-GSDMD_Q29A

   Plasmid

   #224702

   Purpose

   Expression of mutated Gasdermin D_Q29A (GSDMD_Q29A) in transfected mammalian cell lines

   Depositor

   Christopher Overall

   Article

   Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

   Insert

   GSDMD_Q29A (GSDMD Human)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Q29A

   Promoter

   CMV

   Available since

   July 2, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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9. pcDNA3.1-GSDMD_Q29A_H270A

   Plasmid

   #224703

   Purpose

   Expression of mutant Gasdermin D_Q29A_H270A (GSDMD_Q29A_H270A) in transfected mammalian cell lines

   Depositor

   Christopher Overall

   Article

   Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

   Insert

   GSDMD_Q29A_H270A (GSDMD Human)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Q29A and H270A

   Promoter

   CMV

   Available since

   July 2, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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10. pcDNA3.1-GSDMD_D275A

    Plasmid

    #224704

    Purpose

    Expression of mutated Gasdermin D_D275A (GSDMD_D275A) in transfected mammalian cell lines

    Depositor

    Christopher Overall

    Article

    Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

    Insert

    GSDMD_D275A (GSDMD Human)
    

    Use

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    D275A

    Promoter

    CVM

    Available since

    July 2, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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11. pcDNA3.1-GSDMD_H270A_D275A

    Plasmid

    #224705

    Purpose

    Expression of mutated Gasdermin D_H270A_D275A (GSDMD_D275A) in transfected mammalian cell lines

    Depositor

    Christopher Overall

    Article

    Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

    Insert

    GSDMD_Q29A_H270A (GSDMD Human)
    

    Use

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    H270A and D275A

    Promoter

    CMV

    Available since

    July 2, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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12. pD649-HAsp-MDGA2-COMP5AP-AviTag-9xHis

    Plasmid

    #157565

    Purpose

    Mammalian expression of cell-surface protein extracellular domain fused to COMP5AP-AviTag-9xHis. Protein is secreted from cells.

    Depositor

    Chris Garcia

    Article

    Wojtowicz et al Cell. 2020 Aug 20;182(4):1027-1043.e17.

    Insert

    MDGA2 (MDGA2 Human)
    

    Use

    Tags

    COMP5AP-AviTag-9xHis

    Expression

    Mammalian

    Mutation

    Promoter

    CMV/SP6

    Available since

    March 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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13. pcDNA3.1-GSDMD_1-270

    Plasmid

    #218229

    Purpose

    Gasdermin1-270 is a pore-forming GSDMD formed by SARS-CoV-2 3CLpro cleavage. Transfection in HEK293 cells showed GSDMD 1-270 pores secrete 3CLpro, nucleocapsid, and in excess, kill cells by pyroptosis

    Depositor

    Christopher Overall

    Article

    Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

    Insert

    GSDMD (GSDMD Human)
    

    Use

    Tags

    flag

    Expression

    Mammalian

    Mutation

    construct only codes for amino acids 1-270

    Promoter

    Available since

    July 1, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

14. pcDNA3.1-GSDMD_1-275

    Plasmid

    #218230

    Purpose

    Gasdermin-D_1-275 is a pore-forming GSDMD formed by cleavage by host caspases. Transfection in HEK293 cells showed GSDMD 1-275 pores secrete 3CLpro, nucleocapsid; in excess, kills cells by pyroptosis

    Depositor

    Christopher Overall

    Article

    Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

    Insert

    GSDMD (GSDMD Human)
    

    Use

    Tags

    flag

    Expression

    Mammalian

    Mutation

    construct only codes for amino acids 1-275

    Promoter

    Available since

    July 1, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

15. pcDNA3.1-GSDMD_29-484

    Plasmid

    #218231

    Purpose

    Gasdermin-D_29-484 is a non-functional GSDMD formed by SARS-CoV-2 3CLpro cleavage in the N-terminal domain. Transfection in HEK293 cells showed no pore-forming activity or induction of pyroptosis

    Depositor

    Christopher Overall

    Article

    Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

    Insert

    GSDMD (GSDMD Human)
    

    Use

    Tags

    flag

    Expression

    Mammalian

    Mutation

    construct only codes for amino acids 29-484

    Promoter

    Available since

    July 1, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

16. pcDNA3.1-GSDMD_29-270

    Plasmid

    #218232

    Purpose

    Gasdermin-D_29-270 is a non-functional GSDMD formed by two SARS-CoV-2 3CLpro cleavages. Transfection in HEK293 cells showed no pore-forming activity or induction of pyroptosis

    Depositor

    Christopher Overall

    Article

    Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

    Insert

    GSDMD (GSDMD Human)
    

    Use

    Tags

    flag

    Expression

    Mammalian

    Mutation

    construct only codes for amino acids 29-270

    Promoter

    Available since

    July 1, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge