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Plasmid#77244Purpose3rd generation lentiviral gRNA plasmid targeting human FYNDepositorInsertFYN (FYN Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
pT2/shFYN1/GFP4_Seq_B
Plasmid#206135PurposeKnockdown of FYNDepositorInsertFYN shRNA (Fyn Mouse)
UseTagsExpressionMammalianMutationPromoterAvailable sinceSept. 11, 2023AvailabilityAcademic Institutions and Nonprofits only -
pT2/shFYN1/GFP4_Seq_A
Plasmid#206134PurposeKnockdown of FYNDepositorInsertFYN shRNA (Fyn Mouse)
UseTagsExpressionMammalianMutationPromoterAvailable sinceSept. 11, 2023AvailabilityAcademic Institutions and Nonprofits only -
pT2/sh-FYN1-GFP_Seq_C
Plasmid#201399PurposeKnockdown of FYN tyrosine kinase. Construct has inverted repeats to be used in Sleeping Beauty transposon system.DepositorInsertFYN
UseTagsExpressionMammalianMutationPromoterAvailable sinceMay 24, 2023AvailabilityAcademic Institutions and Nonprofits only -
pHA853 - mec-4p::Fynempty
Plasmid#139210PurposeControl vector for Fyn kinase expression in mec-4 neuronsDepositorInsertFyn (FYN Human)
UseTagsExpressionWormMutationdeletion and frame shift to prevent Fyn expressionPromoterAvailable sinceDec. 7, 2020AvailabilityAcademic Institutions and Nonprofits only -
pHA852 - mec-4p::FynY531F
Plasmid#139209PurposeExpresses activated Fyn kinase in mec-4 neuronsDepositorInsertFyn (FYN Human)
UseTagsExpressionWormMutationY531FPromoterAvailable sinceDec. 7, 2020AvailabilityAcademic Institutions and Nonprofits only -
FYN gRNA (BRDN0001147012)
Plasmid#77242Purpose3rd generation lentiviral gRNA plasmid targeting human FYNDepositorInsertFYN (FYN Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
FYN gRNA (BRDN0001147691)
Plasmid#77243Purpose3rd generation lentiviral gRNA plasmid targeting human FYNDepositorInsertFYN (FYN Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
Cytosolic Fyn FRET Biosensor
Plasmid#124654PurposeFRET biosensor. The highly sensitive biosensor has a mutated SH2 domain, ECFP and YPetDepositorInsertSynthetic gene containing ECFP-SH2 domain-substrate-linker-YPet
UseTagsExpressionMammalianMutationPromoterAvailable sinceFeb. 18, 2022AvailabilityAcademic Institutions and Nonprofits only -
pRK5 Fyn SH2:R176E
Plasmid#16035DepositorInsertc-Fyn (FYN Human)
UseTagsExpressionMammalianMutationSH2 point mutant: R176EPromoterAvailable sinceNov. 2, 2007AvailabilityAcademic Institutions and Nonprofits only -
pMSCVneo-FYN-WT-Myc-FLAG
Plasmid#74510PurposeRetroviral expression of FYNDepositorInsertFYN (FYN Human)
UseRetroviralTagsFLAG and MycExpressionMammalianMutationPromoterunknownAvailable sinceMay 20, 2016AvailabilityAcademic Institutions and Nonprofits only -
pHA850 - osm-10p::FynY531F
Plasmid#139207PurposeExpress activated Fyn kinase in osm-10 neuronsDepositorInsertFyn (FYN Human)
UseTagsExpressionWormMutationY531FPromoterAvailable sinceDec. 7, 2020AvailabilityAcademic Institutions and Nonprofits only -
pHA851 - osm-10p::Fynempty
Plasmid#139208PurposeControl vector for Fyn kinase expression in osm-10 neuronsDepositorInsertFyn (FYN Human)
UseTagsExpressionWormMutationdeletion and frame shift to prevent Fyn expressionPromoterAvailable sinceDec. 7, 2020AvailabilityAcademic Institutions and Nonprofits only -
pLenti-CMV-Fyn-cGASΔN-HA
Plasmid#130922PurposeExpresses human cGASΔN (aa160-522)-HA with an N terminal fusion of the Fyn dual acylation motif (aa1-16); Puromycin selection markerDepositorInsertFyn-ΔNcGAS
UseTagsHAExpressionMammalianMutationcGAS N terminus (aa1-159) replaced with the dual …PromoterCMVAvailable sinceAug. 27, 2019AvailabilityAcademic Institutions and Nonprofits only -
CMVTO-Fyn-nTVMVpmut-tevs-AP4-tevs-P3-cTVMVp
Plasmid#179668PurposeMembrane-bound (Fyn) TEVP-inducible caged-cTVMVPDepositorInsertCaged cTVMVP
UseTagsExpressionMammalianMutationPromoterAvailable sinceMarch 23, 2022AvailabilityAcademic Institutions and Nonprofits only -
SH4-FRB-mRFP
Plasmid#100741PurposeTo express a plasma membrane "anchor" in mammalian cells to hot-wire endocytosisDepositorInsertFyn
UseTagsFRB and mRFPExpressionMammalianMutationSH4 domain onlyPromoterCMVAvailable sinceSept. 29, 2017AvailabilityAcademic Institutions and Nonprofits only -
pRK5 DN-Src
Plasmid#19965DepositorInsertSrc (SRC Chicken)
UseTagsExpressionMammalianMutationK295MPromoterAvailable sinceDec. 16, 2008AvailabilityAcademic Institutions and Nonprofits only -
hnRNPA2_266-341
Plasmid#118821PurposeBacterial expression of hnRNPA2 truncationDepositorInserthnRNPA2 (HNRNPA2B1 Human)
UseTagsHis and TEVExpressionBacterialMutationcontains amino acids 266-341PromoterAvailable sinceApril 25, 2019AvailabilityAcademic Institutions and Nonprofits only -
hnRNPA2_190-303
Plasmid#118822PurposeBacterial expression of hnRNPA2 truncation (residues 190 to 302).DepositorInserthnRNPA2 (HNRNPA2B1 Human)
UseTagsHis tag and TEVExpressionBacterialMutationcontains amino acids 190-302PromoterAvailable sinceApril 25, 2019AvailabilityAcademic Institutions and Nonprofits only -
pME-memGFP-P2A
Plasmid#80809PurposeFyn myristoylation domain fused to N-terminus of GFP (memGFP) without stop codon, followed by P2ADepositorInsertpME-memGFP-P2A
UseTagsExpressionMammalianMutationPromoterAvailable sinceNov. 1, 2016AvailabilityAcademic Institutions and Nonprofits only