We narrowed to 10,454 results for: ESP

1. AiP1049-pAAV-mscRE13-minBGpromoter-tTA2-WPRE-hGHpA

   Plasmid

   #163482

   Purpose

   Direct-expressing tTA2 AAV Virus. Alias: AiP1049 - pAAV-AiE2013m-minBG-tTA2-WPRE-HGHpA

   Depositor

   Allen Institute for Brain Science, Bosiljka Tasic

   Article

   Graybuck et al Neuron. 2021 Mar 23. pii: S0896-6273(21)

   Insert

   tTA2
   

   Use

   AAV

   Promoter

   Beta Globin minimal promoter

   Available Since

   Feb. 26, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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2. pGL4.23-CD69 CaRE1 (minus strand)

   Plasmid

   #91842

   Purpose

   Luciferase reporter for CD69 enhancer (IGI-P0619)

   Depositor

   Jacob Corn

   Article

   Simeonov et al Nature. 2017 Sep 7;549(7670):111-115. do

   Insert

   CD69 CaRE1 (minus strand) (CD69 Human)
   

   Use

   Luciferase

   Expression

   Mammalian

   Mutation

   Perfect match to reference sequence

   Available Since

   May 31, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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3. pGL4.23-IL2RA CaRE6 (minus strand)

   Plasmid

   #91840

   Purpose

   Luciferase reporter for IL2RA enhancer (IGI-P0617)

   Depositor

   Jacob Corn

   Article

   Simeonov et al Nature. 2017 Sep 7;549(7670):111-115. do

   Insert

   IL2RA CaRE6 (minus strand) (IL2RA Human)
   

   Use

   Luciferase

   Expression

   Mammalian

   Mutation

   rs7893467 C>A

   Available Since

   May 30, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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4. pGL4.23-IL2RA CaRE6 (plus strand)

   Plasmid

   #91839

   Purpose

   Luciferase reporter for IL2RA enhancer (IGI-P0616)

   Depositor

   Jacob Corn

   Article

   Simeonov et al Nature. 2017 Sep 7;549(7670):111-115. do

   Insert

   IL2RA CaRE6 (plus strand) (IL2RA Human)
   

   Use

   Luciferase

   Expression

   Mammalian

   Mutation

   rs7893467 G>T, rs11256448 A>G

   Available Since

   May 30, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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5. pGL4.23-CD69 CaRE2 (plus strand)

   Plasmid

   #91848

   Purpose

   Luciferase reporter for CD69 enhancer (IGI-P0625)

   Depositor

   Jacob Corn

   Article

   Simeonov et al Nature. 2017 Sep 7;549(7670):111-115. do

   Insert

   CD69 CaRE2 (plus strand) (CD69 Human)
   

   Use

   Luciferase

   Expression

   Mammalian

   Mutation

   Perfect match to reference sequence

   Available Since

   May 30, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pGL4.23-CD69 CaRE2 (minus strand)

   Plasmid

   #91843

   Purpose

   Luciferase reporter for CD69 enhancer (IGI-P0620)

   Depositor

   Jacob Corn

   Article

   Simeonov et al Nature. 2017 Sep 7;549(7670):111-115. do

   Insert

   CD69 CaRE2 (minus strand) (CD69 Human)
   

   Use

   Luciferase

   Expression

   Mammalian

   Mutation

   Perfect match to reference sequence

   Available Since

   May 30, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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7. pEN_TTmiRc2_p53(R280K)_V5

   Plasmid

   #136525

   Purpose

   Used as a donor vector to clone into pSLIK

   Depositor

   Kevin Janes

   Article

   Pereira et al Sci Signal. 2020 Apr 14;13(627). pii: 13

   Insert

   p53(R280K) (TP53 Human)
   

   Use

   Entry vector for gateway cloning

   Tags

   V5

   Mutation

   p53(R280K)V5 was cloned from pLenti6-p53-R280K-V5…

   Availability

   Academic Institutions and Nonprofits only

   

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8. pCMV-ABE8.8m-WT-P2A-EGFP (BKS953)

   Plasmid

   #242651

   Purpose

   CMV promoter expression plasmid for human codon optimized ABE8.8m A-to-G base editor with SpCas9(D10A) and P2A-EGFP

   Depositor

   Benjamin Kleinstiver

   Article

   Alves et al Nat Biomed Eng. 2025 Sep 11:10.1038/s415

   Insert

   pCMV-ABE8.8m-SpCas9-P2A-EGFP
   

   Use

   CRISPR

   Expression

   Mammalian

   Mutation

   ABE8.8 mutations in TadA

   Promoter

   CMV and T7

   Available Since

   Oct. 9, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. AiP1010-pAAV-mscRE4-minBGpromoter-iCre-WPRE-hGHpA

   Plasmid

   #163476

   Purpose

   Direct-expressing iCre AAV Virus. Alias: AiP1010 - pAAV-AiE2004m-minBG-iCre-WPRE-HGHpA

   Depositor

   Allen Institute for Brain Science, Bosiljka Tasic

   Article

   Graybuck et al Neuron. 2021 Mar 23. pii: S0896-6273(21)

   Insert

   iCre
   

   Use

   AAV

   Promoter

   Beta Globin minimal promoter

   Available Since

   March 29, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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10. AiP11818-pAAV-AiE2004m_3xC2-minCMV-SYFP2-WPRE3-BGHpA (Alias: CN1818)

    Plasmid

    #164458

    Purpose

    AiE2004m_3xC2 is an optimized enhancer sequence designed to drive AAV-mediated transgene expression in L4/5_IT cortical neurons

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Graybuck et al Neuron. 2021 Mar 23. pii: S0896-6273(21)

    Insert

    SYFP2
    

    Use

    AAV

    Promoter

    minCMV

    Available Since

    Feb. 25, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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11. pUCM-CLYBL-NGN2-BRN3A

    Plasmid

    #165597

    Purpose

    Donor construct for insertion of NGN2 and BRN3A into the CLYBL safe harbor site. This is an all-in-one doxycycline-inducible construct, enabling iPSC differentiation into peripheral sensory neurons.

    Depositor

    Carsten Bönnemann

    Article

    Nickolls et al Cell Rep. 2020 Jan 21;30(3):932-946.e7.

    Inserts

    Neurogenin 2 (NEUROG2 Human)
    BRN3A (POU4F1 Human)
    EGFP
    Puromycin N-acetyl transferase
    rtTA3G
    SBP Delta-LNGFR
    

    Use

    CRISPR and TALEN

    Expression

    Mammalian

    Promoter

    CAG, EF-1alpha, Endogenous CLYBL (splice acceptor…

    Available Since

    March 3, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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12. P3-dCas9-Tet1-GFP-Puro

    Plasmid

    #190728

    Purpose

    Expression of human spdCas9-Tet1 fusion for targeted DNA methylation in mammalian cell. EGFP-puromycin double marker under an independent CMV promoter. Cloning backbone for spgRNA (BbsI)

    Depositor

    Maja Jagodic

    Article

    Pahlevan Kakhki et al Nat Commun. 2024 Jul 30;15(1):6419. doi:

    Insert

    dCas9-tet1
    

    Use

    CRISPR

    Tags

    3XFLAG and SV40 NLS

    Expression

    Mammalian

    Mutation

    Changed Pro434 codon from CCG to CCC and Gly468 f…

    Promoter

    pCAG

    Available Since

    July 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. AiP12251-pAAV-AiE0453m-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2251)

    Plasmid

    #164453

    Purpose

    AiE0453m is an enhancer sequence designed to drive AAV-mediated transgene expression in L5_ET cortical neurons

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Graybuck et al Neuron. 2021 Mar 23. pii: S0896-6273(21)

    Insert

    SYFP2
    

    Use

    AAV

    Promoter

    minBetaGlobin

    Available Since

    Feb. 25, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pcDNA5-Flag-BRD4-7D

    Plasmid

    #90007

    Purpose

    expresses 7D mutant BRD4

    Depositor

    Kornelia Polyak

    Article

    Shu et al Nature. 2016 Jan 21;529(7586):413-7. doi

    Insert

    BRD4 (BRD4 Human)
    

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    Changed 484S to 484D, 488S to 488D, 492S to 492D,…

    Available Since

    July 10, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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15. pcDNA5-Flag-BRD4-7A

    Plasmid

    #90006

    Purpose

    expresses 7A mutant BRD4

    Depositor

    Kornelia Polyak

    Article

    Shu et al Nature. 2016 Jan 21;529(7586):413-7. doi

    Insert

    BRD4 (BRD4 Human)
    

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    Changed 484S to 484A, 488S to 488A, 492S to 492A,…

    Available Since

    July 10, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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16. AiP12014-pAAV-AiE2004m-minCMV-SYFP2-WPRE3-BGHpA (Alias: CN2014)

    Plasmid

    #164457

    Purpose

    AiE2004m is an enhancer sequence designed to drive AAV-mediated transgene expression in L4/5_IT cortical neurons

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Graybuck et al Neuron. 2021 Mar 23. pii: S0896-6273(21)

    Insert

    SYFP2
    

    Use

    AAV

    Promoter

    minCMV

    Available Since

    Feb. 25, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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17. pαH-rS2d-HexaPro

    Plasmid

    #183515

    Purpose

    Mammalian cell expression of SARS-CoV-2 Spike protein rS2d-HexaPro with (682-685) furin side replaced with GSAS and mutation S383C, D985C, F817P, A892P, A899P, A942P, K986P,V987P

    Depositor

    Priyamvada Acharya

    Article

    Gobeil et al Mol Cell. 2022 Jun 2;82(11):2050-2068.e6

    Insert

    Spike (S-GSAS-rS2d.HexaPro) (S Severe acute respiratory syndrome coronavirus 2)
    

    Tags

    2X Strep-Tag II, 8X His tag, and HRV3C cleavage s…

    Expression

    Mammalian

    Mutation

    Ectodomain (AAs 1-1208); 682-685 (furin site = RR…

    Available Since

    May 25, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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18. AiP978-pAAV-mscRE4-minBGpromoter-FlpO-WPRE-hGHpA

    Plasmid

    #163472

    Purpose

    Direct-expressing FlpO AAV Virus. Alias: AiP978 - pAAV-AiE2004m-minBG-FlpO-WPRE-HGHpA

    Depositor

    Allen Institute for Brain Science, Bosiljka Tasic

    Article

    Graybuck et al Neuron. 2021 Mar 23. pii: S0896-6273(21)

    Insert

    FlpO
    

    Use

    AAV

    Promoter

    Beta Globin minimal promoter

    Available Since

    Feb. 26, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pQ-Elo-HB-C-A(1-630)

    Plasmid

    #171086

    Purpose

    Co-expresses of ΔC-ELOA containing Elongin complex in bacteria. The resulting plasmid was used to generate a single expression construct encoding all 3Elongin subunits, with a 6-His tag on ELOB

    Depositor

    Joan Conaway

    Article

    He et al Proc Natl Acad Sci U S A. 2021 Sep 28;11

    Inserts

    Elongin B (ELOB Human)
    Elongin C (ELOC Human)
    Elongin A (ELOA Human)
    

    Tags

    His

    Expression

    Bacterial

    Mutation

    Deleted N-term 26aa and C-term 142aa for mutant e…

    Promoter

    T5 promoter

    Available Since

    July 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. AiP12254-pAAV-AiE0459m-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2254)

    Plasmid

    #164454

    Purpose

    AiE0459m is an enhancer sequence designed to drive AAV-mediated transgene expression in L5_ET cortical neurons

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Graybuck et al Neuron. 2021 Mar 23. pii: S0896-6273(21)

    Insert

    SYFP2
    

    Use

    AAV

    Promoter

    minBetaGlobin

    Available Since

    March 16, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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