We narrowed to 5,473 results for: KRAS

1. pLX304-YAP1(S94A)

   Plasmid

   #59145

   Purpose

   YAP1 serine 94 o alanine mutants which disrupts binding to TEAD transcription factors

   Depositor

   William Hahn

   Article

   Shao et al Cell. 2014 Jul 3;158(1):171-84. doi: 10.

   Insert

   YAP1 (YAP1 Human)
   

   Use

   Lentiviral

   Mutation

   S94A

   Promoter

   CMV

   Available Since

   Aug. 18, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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2. R701-X71-527: His6-tev-Hs.CALM1(1-80)

   Plasmid

   #159694

   Purpose

   E. coli protein expression of His6-tev-Hs.CALM1(1-80)

   Depositor

   Dominic Esposito

   Article

   Agamasu et al Biophys J. 2019 Mar 19;116(6):1049-1063.

   Insert

   His6-tev-Hs.CALM1(1-80) (CALM1 Human)
   

   Tags

   His6-tev

   Expression

   Bacterial

   Available Since

   Oct. 5, 2020

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. R701-X72-527: His6-tev-Hs.CALM1(76-148)

   Plasmid

   #159695

   Purpose

   E. coli protein expression of His6-tev-Hs.CALM1(76-148)

   Depositor

   Dominic Esposito

   Article

   Agamasu et al Biophys J. 2019 Mar 19;116(6):1049-1063.

   Insert

   His6-tev-Hs.CALM1(76-148) (CALM1 Human)
   

   Tags

   His6-tev

   Expression

   Bacterial

   Available Since

   Oct. 5, 2020

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pLX304-YAP1 _TA

   Plasmid

   #59143

   Purpose

   YAP1 mutants that harbor a deletion of the transcriptional activation domain

   Depositor

   William Hahn

   Article

   Shao et al Cell. 2014 Jul 3;158(1):171-84. doi: 10.

   Insert

   YAP1 (YAP1 Human)
   

   Use

   Lentiviral

   Mutation

   TA (transactivation) domain deleted; aa291-497

   Promoter

   CMV

   Available Since

   Oct. 23, 2014

   Availability

   Academic Institutions and Nonprofits only

5. pLX304-YAP1 _60-89

   Plasmid

   #59144

   Purpose

   YAP1 mutants that harbored a deletion of amino acide at 60-89 position, which disrupts binding to TEAD transcription factors

   Depositor

   William Hahn

   Article

   Shao et al Cell. 2014 Jul 3;158(1):171-84. doi: 10.

   Insert

   YAP1 (YAP1 Human)
   

   Use

   Lentiviral

   Mutation

   aa60-89 deleted

   Promoter

   CMV

   Available Since

   Aug. 19, 2014

   Availability

   Academic Institutions and Nonprofits only

6. pLX304-YAP1 _PDZ

   Plasmid

   #59147

   Purpose

   YAP1 mutants that harbored a deletion of the 5 amino acids

   Depositor

   William Hahn

   Article

   Shao et al Cell. 2014 Jul 3;158(1):171-84. doi: 10.

   Insert

   YAP1 (YAP1 Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   PDZ binding domain (last 5aa) deleted

   Promoter

   CMV

   Available Since

   Oct. 23, 2014

   Availability

   Academic Institutions and Nonprofits only

7. Lenti-BaeI-Pgk-Cre

   Plasmid

   #173663

   Purpose

   Vector with BaeI site to allow cloning of custom sgRNA into vector containing Cre-recombinase

   Depositor

   Charles Swanton

   Article

   Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

   Insert

   BaeI site
   

   Use

   CRISPR, Cre/Lox, and Lentiviral

   Available Since

   May 12, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. Lenti-sgNT.3#3/Cre

   Plasmid

   #173662

   Purpose

   Expresses a NT.3-targeting gRNA and Cre-recombinase

   Depositor

   Charles Swanton

   Article

   Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

   Insert

   Non-targeting gRNA
   

   Use

   CRISPR, Cre/Lox, and Lentiviral

   Available Since

   May 12, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pLX304-YAP1 _SH3bm

   Plasmid

   #59141

   Purpose

   YAP1 mutants that harbored a deletion of SH3 binding motif, which disrupts interaction of YES1 with YAP1

   Depositor

   William Hahn

   Article

   Shao et al Cell. 2014 Jul 3;158(1):171-84. doi: 10.

   Insert

   YAP1 (YAP1 Human)
   

   Use

   Lentiviral

   Mutation

   SH3 domain deleted (aa278-290)

   Available Since

   Oct. 23, 2014

   Availability

   Academic Institutions and Nonprofits only

10. Lenti-sgTsc1#1/Cre

    Plasmid

    #173657

    Purpose

    Expresses a Tsc1-targeting gRNA and Cre-recombinase

    Depositor

    Charles Swanton

    Article

    Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

    Insert

    gRNA targeting Tsc1 (Tsc1 Mouse)
    

    Use

    CRISPR, Cre/Lox, and Lentiviral

    Available Since

    Dec. 22, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. Lenti-sgTsc1#2/Cre

    Plasmid

    #173658

    Purpose

    Expresses a Tsc1-targeting gRNA and Cre-recombinase

    Depositor

    Charles Swanton

    Article

    Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

    Insert

    gRNA targeting Tsc1 (Tsc1 Mouse)
    

    Use

    CRISPR, Cre/Lox, and Lentiviral

    Available Since

    Oct. 18, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. Lenti-sgNf2#1/Cre

    Plasmid

    #173643

    Purpose

    Expresses a Nf2-targeting gRNA and Cre-recombinase

    Depositor

    Charles Swanton

    Article

    Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

    Insert

    gRNA targeting Nf2 (Nf2 Mouse)
    

    Use

    CRISPR, Cre/Lox, and Lentiviral

    Available Since

    May 18, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. Lenti-sgRbm10#2/Cre

    Plasmid

    #173651

    Purpose

    Expresses a Rbm10-targeting gRNA and Cre-recombinase

    Depositor

    Charles Swanton

    Article

    Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

    Insert

    gRNA targeting Rbm10 (Rbm10 Mouse)
    

    Use

    CRISPR, Cre/Lox, and Lentiviral

    Available Since

    June 8, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. Lenti-sgWrn#1/Cre

    Plasmid

    #173625

    Purpose

    Expresses a Wrn-targeting gRNA and Cre-recombinase

    Depositor

    Charles Swanton

    Article

    Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

    Insert

    gRNA targeting Wrn (Wrn Mouse)
    

    Use

    CRISPR, Cre/Lox, and Lentiviral

    Available Since

    June 7, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. Lenti-sgPole#2/Cre

    Plasmid

    #173610

    Purpose

    Expresses a Pole-targeting gRNA and Cre-recombinase

    Depositor

    Charles Swanton

    Article

    Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

    Insert

    gRNA targeting Pole (Pole Mouse)
    

    Use

    CRISPR, Cre/Lox, and Lentiviral

    Available Since

    June 7, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. Lenti-sgWrn#2/Cre

    Plasmid

    #173626

    Purpose

    Expresses a Wrn-targeting gRNA and Cre-recombinase

    Depositor

    Charles Swanton

    Article

    Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

    Insert

    gRNA targeting Wrn (Wrn Mouse)
    

    Use

    CRISPR, Cre/Lox, and Lentiviral

    Available Since

    June 7, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. Lenti-sgNf2#2/Cre

    Plasmid

    #173644

    Purpose

    Expresses a Nf2-targeting gRNA and Cre-recombinase

    Depositor

    Charles Swanton

    Article

    Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

    Insert

    gRNA targeting Nf2 (Nf2 Mouse)
    

    Use

    CRISPR, Cre/Lox, and Lentiviral

    Available Since

    May 18, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. Lenti-sgPole#1/Cre

    Plasmid

    #173609

    Purpose

    Expresses a Pole-targeting gRNA and Cre-recombinase

    Depositor

    Charles Swanton

    Article

    Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

    Insert

    gRNA targeting Pole (Pole Mouse)
    

    Use

    CRISPR, Cre/Lox, and Lentiviral

    Available Since

    May 12, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. JDW 295 (pDONR-Dll4-F2-ETS#2-WT-8X)

    Plasmid

    #156412

    Purpose

    Gateway middle entry clone containing an 8X multimerized ETS#2 DNA binding site from the murine Dll4 intronic enhancer

    Depositor

    Joshua Wythe

    Article

    Fish et al Circ Res. 2020 Jun 17. doi: 10.1161/CIRC

    Insert

    murine Dll4 F2- ETS site B/ site #2, 8X
    

    Use

    Gateway cloning

    Available Since

    Aug. 19, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pBabe K-Ras 12V

    Plasmid

    #12544

    Depositor

    Channing Der

    Article

    Khosravi-Far et al Mol Cell Biol. 1996 Jul . 16(7):3923-33.

    Insert

    K-Ras 12V (KRAS Human)
    

    Use

    Retroviral

    Expression

    Mammalian

    Mutation

    12V constituitively activated

    Available Since

    Sept. 8, 2006

    Availability

    Academic Institutions and Nonprofits only

    

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