We narrowed to 1,562 results for: ICL

1. mCherry-FKBP-TPD54(R159E)

   Plasmid

   #172453

   Purpose

   Expression of Tumor Protein D52 like 2 (TPD54/TPD52L2) with N-terminal mCherry-FKBP tag R159E mutant

   Depositor

   Stephen Royle

   Article

   Larocque et al J Cell Biol. 2021 Oct 4;220(10). pii: 21

   Insert

   TPD54 (TPD52L2 Human)
   

   Use

   Tags

   mCherry-FKBP

   Expression

   Mammalian

   Mutation

   changed Arginine 159 to Glutamic Acid

   Promoter

   CMV

   Available since

   Aug. 4, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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2. K15-TK/pGL3

   Plasmid

   #44267

   Depositor

   George Cotsarelis

   Article

   Ito et al Nat Med. 2005 Dec;11(12):1351-4. Epub 20

   Insert

   K15 promoter (-4.8) (Krt15 Mouse)
   

   Use

   Mouse Targeting; Thymidine kinase

   Tags

   HSV-1 TK

   Expression

   Mammalian

   Mutation

   Contains the murine K15 promoter (-4.8) fragment

   Promoter

   murine K15 promoter (-4.8) fragment

   Available since

   April 2, 2013

   Availability

   Academic Institutions and Nonprofits only

3. pGAPTrap-IRESMuro

   Plasmid

   #82336

   Purpose

   Base vector targeting genes to the GAPDH locus of human cells. Inserted genes are expressed from a 2A sequence at the C terminus of GAPDH. Puromycin resistance is encoded by the Muro gene.

   Depositor

   Ed Stanley

   Article

   Kao et al Stem Cell Reports. 2016 Sep 1. pii: S221

   Insert

   IRESMuro
   

   Use

   Synthetic Biology

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Oct. 3, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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4. pGAPTrap-mtagtdTom_IRESMuro

   Plasmid

   #82355

   Purpose

   Vector targeting the mTagtandem tomato gene to the GAPDH locus of human cells. It is expressed from a 2A sequence at the C terminus of GAPDH. Puromycin resistance is encoded by the Muro gene.

   Depositor

   Ed Stanley

   Article

   Kao et al Stem Cell Reports. 2016 Sep 1. pii: S221

   Insert

   mtagTandemTomato-IRESMuro
   

   Use

   Synthetic Biology

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Oct. 3, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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5. pSN672

   Plasmid

   #177362

   Purpose

   Expresses human KIF1A(1-393) fused with leucine zipper and His tag

   Depositor

   Shinsuke Niwa

   Article

   Anazawa et al Proc Natl Acad Sci U S A. 2022 Aug 9;119

   Insert

   KIF1A (KIF1A Human)
   

   Use

   Tags

   His tag and Leucine zipper

   Expression

   Bacterial

   Mutation

   Promoter

   T7

   Available since

   Aug. 10, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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6. mCherry-FKBP-TPD54(L53P,L67P)

   Plasmid

   #172458

   Purpose

   Expression of Tumor Protein D52 like 2 (TPD54/TPD52L2) with N-terminal mCherry-FKBP tag L53P,L67P mutant

   Depositor

   Stephen Royle

   Article

   Larocque et al J Cell Biol. 2021 Oct 4;220(10). pii: 21

   Insert

   TPD54 (TPD52L2 Human)
   

   Use

   Tags

   mCherry-FKBP

   Expression

   Mammalian

   Mutation

   changed Leucines 53 and 67 to proline (breaks coi…

   Promoter

   CMV

   Available since

   Aug. 9, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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7. MO70-N-Flag-hCRACR2A-isoform-a-Q604L

   Plasmid

   #79595

   Purpose

   Transient and retroviral expression

   Depositor

   Yousang Gwack

   Article

   Srikanth et al Sci Signal. 2016 Mar 22;9(420):ra31. doi

   Insert

   CRACR2A-isoform-a (CRACR2A Human)
   

   Use

   Retroviral

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Q604L

   Promoter

   CMV

   Available since

   June 29, 2016

   Availability

   Academic Institutions and Nonprofits only

8. MO70-N-Flag-hCRACR2A-isoform-a-T559N

   Plasmid

   #79594

   Purpose

   Transient and retroviral expression

   Depositor

   Yousang Gwack

   Article

   Srikanth et al Sci Signal. 2016 Mar 22;9(420):ra31. doi

   Insert

   CRACR2A-isoform-a (CRACR2A Human)
   

   Use

   Retroviral

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   T559N

   Promoter

   CMV

   Available since

   June 29, 2016

   Availability

   Academic Institutions and Nonprofits only

9. pET-hIRF5-V5(4D)-LPETG

   Plasmid

   #237225

   Purpose

   Expresses LPETG-tagged, constitutively active human IRF5 variant in bacteria

   Depositor

   Elliot Chaikof

   Article

   Eweje et al Nat Biotechnol. 2025 May 15. doi: 10.103

   Insert

   Interferon regulatory factor 5 (IRF5 Human)
   

   Use

   Tags

   6xHis

   Expression

   Bacterial

   Mutation

   S451D, S453D, S456D, S462D

   Promoter

   Available since

   July 29, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. MZB035

    Plasmid

    #217834

    Purpose

    Bacterial expression of human AP3D1 (1-617) and AP3S1 AP-3 core hemicomplex

    Depositor

    Richard Baker

    Article

    Begley et al Proc Natl Acad Sci U S A. 2024 Dec 24;12

    Inserts

    AP3D1 (AP3D1 Human)
    AP3S1 (AP3S1 Human)
    

    Use

    Tags

    GST

    Expression

    Bacterial

    Mutation

    Removed residues 618-1153 from AP3D1

    Promoter

    Available since

    May 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. p70.unipA.NGFR.mCMV.PGK.mBFP2.p27K.WPRE

    Plasmid

    #228766

    Purpose

    insert a blue fluorescent protein mBFP2, a cyclin-dependent kinase inhibitor p27K

    Depositor

    Ferdinando Pucci

    Article

    Ziglari et al Cancer Res. 2025 Mar 3;85(5):859-874. do

    Insert

    p27 kinase inhibitor (Cdkn1b Mouse)
    

    Use

    Tags

    mTagBFP2

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    May 8, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pStreptagII 3C SMO

    Plasmid

    #234995

    Purpose

    Expression of a Strep-tag II labeled on its N-terminus receptor, with the Smoothened (Smo) receptor

    Depositor

    Daniel Leahy, Monica Gonzalez-Magaldi

    Article

    Gonzalez-Magaldi et al bioRxiv [Preprint]. 2024 Nov 28:2024.11.

    Insert

    SMO (SMO Human)
    

    Use

    Tags

    Streptag-II, HRV 3C site

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    April 22, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pHIE323-LPIV Puro-P2A-miRFP720 ZF6x12-C-DsRed-Express2(x6) phEF1α-BlastR

    Plasmid

    #201539

    Purpose

    Landing pad integration vector used to generate ZF6 synTF reporter line (HIE156), assembled with pPD1178 (destination vector), pHIE324-329 (TUPV1-6), pHIE280 (TUPV7), pPD1157 (linker)

    Depositor

    Joshua Leonard

    Article

    Peruzzi et al Nat Commun. 2024 Jul 4;15(1):5618. doi:

    Inserts

    PuromycinR-P2A-miRFP720
    ZF6x12-C-DsRed-Express2(x6)
    BlasticidinR
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    None, ZF6x12(C)_YB_TATA Minimal Promoter, and hEF…

    Available since

    Dec. 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. p50.mALDH1A1.CD63-GFP.wpre

    Plasmid

    #226770

    Purpose

    CD63-GFP in p52 (mAldh1a backbone)

    Depositor

    Ferdinando Pucci

    Article

    Gonzalez-Callejo et al PLoS One. 2023 Feb 3;18(2):e0279400. doi

    Insert

    CD63 (CD63 )
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Nov. 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pSN554

    Plasmid

    #177361

    Purpose

    Expresses human KIF1A(1-393) fused with leucine zipper, mScarlet and StrepII tag

    Depositor

    Shinsuke Niwa

    Article

    Anazawa et al Proc Natl Acad Sci U S A. 2022 Aug 9;119

    Insert

    KIF1A (KIF1A Human)
    

    Use

    Tags

    Leucine zipper, StrepII tag, and mScarlet

    Expression

    Bacterial

    Mutation

    Promoter

    T7

    Available since

    Aug. 10, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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16. pIRESneo2 mycBioID-Tollip M240A,F241A

    Plasmid

    #178055

    Purpose

    myc-BioID fused to human Tollip carrying CUE domain mutations cloned into the pIRESneo2 plasmid. For generation of stable expressing mammalian cells used for proximity dependent biotin labelling.

    Depositor

    David Tumbarello

    Article

    Ryan et al EMBO J. 2020 Jun 2;39(11):e102539. doi:

    Insert

    Toll-Interacting Protein (TOLLIP Human)
    

    Use

    Tags

    mycBioID

    Expression

    Mammalian

    Mutation

    Changed Methionine 240 to Alanine and changed Phe…

    Promoter

    CMV

    Available since

    Dec. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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17. pFastBac1_GI.1_A37C-A44C

    Plasmid

    #162582

    Purpose

    Expresses norovirus GI.1 VP1 protein with mutations A37C-A44C in Sf9 insect cells

    Depositor

    Peter Kwong

    Article

    Verardi et al NPJ Vaccines. 2020 Dec 14;5(1):110. doi:

    Insert

    VP1 protein from human norovirus GI.1
    

    Use

    Tags

    Expression

    Insect

    Mutation

    Alanine 37 changed to Cysteine and Alanine 44 cha…

    Promoter

    polyhedring

    Available since

    May 7, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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18. pFastBac1_GI.1_Q141V-P221L

    Plasmid

    #162584

    Purpose

    Expresses norovirus GI.1 VP1 protein with mutations Q141V-P221L in Sf9 insect cells

    Depositor

    Peter Kwong

    Article

    Verardi et al NPJ Vaccines. 2020 Dec 14;5(1):110. doi:

    Insert

    VP1 protein from human norovirus GI.1
    

    Use

    Tags

    Expression

    Insect

    Mutation

    Glutamine 141 changed to Valine and Proline 221 c…

    Promoter

    polyhedrin

    Available since

    May 7, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pFastBac1_GI.1_L144C-P221C

    Plasmid

    #162585

    Purpose

    Expresses norovirus GI.1 VP1 protein with mutations L144C-P221C in Sf9 insect cells

    Depositor

    Peter Kwong

    Article

    Verardi et al NPJ Vaccines. 2020 Dec 14;5(1):110. doi:

    Insert

    VP1 protein from human norovirus GI.1
    

    Use

    Tags

    Expression

    Insect

    Mutation

    Leucine 144 changed to Cysteine and Proline 221 c…

    Promoter

    polyhderin

    Available since

    May 7, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pFastBac1_GI.1_G131C-N172C

    Plasmid

    #162586

    Purpose

    Expresses norovirus GI.1 VP1 protein with mutations G131C-N172C in Sf9 insect cells

    Depositor

    Peter Kwong

    Article

    Verardi et al NPJ Vaccines. 2020 Dec 14;5(1):110. doi:

    Insert

    VP1 protein from human norovirus GI.1
    

    Use

    Tags

    Expression

    Insect

    Mutation

    Glycine 131 changed to Cysteine and Asparagine 17…

    Promoter

    polyhedrin

    Available since

    May 7, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. pFastBac1_GI.1_N167C-L169C

    Plasmid

    #162587

    Purpose

    Expresses norovirus GI.1 VP1 protein with mutations N167C-L169C in Sf9 insect cells

    Depositor

    Peter Kwong

    Article

    Verardi et al NPJ Vaccines. 2020 Dec 14;5(1):110. doi:

    Insert

    VP1 protein from human norovirus GI.1
    

    Use

    Tags

    Expression

    Insect

    Mutation

    Asparagine 167 changed to Cysteine and Leucine 16…

    Promoter

    polyhedrin

    Available since

    May 7, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. pU6_empty-sgRNA(PP7)

    Plasmid

    #232432

    Purpose

    empty gRNA backbone which contains the PP7 aptamer in the scaffold tetraloop

    Depositor

    Gil Westmeyer

    Article

    Geilenkeuser et al Cell. 2025 May 15;188(10):2637-2655.e31.

    Insert

    PP7-tagged sgRNA scaffold driven by human U6 promoter
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    April 10, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. pCMV-MMLV-gag-hMLH1dn

    Plasmid

    #195513

    Purpose

    MMLV-Gag fused to hMLH1dn with TSTLLMENSS cleavage site between Gag-NES and hMLH1dn. For production of virus like particles with base-editor RNP cargo.

    Depositor

    Hyongbum Kim

    Article

    Yu et al Cell. 2023 Apr 21:S0092-8674(23)00331-8.

    Insert

    hMLH1dn (MLH1 Human)
    

    Use

    Virus like particle

    Tags

    FLAG, NES, and Protease cleavate site

    Expression

    Mammalian

    Mutation

    Human MLH1 del754-756

    Promoter

    CMV

    Available since

    May 2, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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24. pCMV_ABE8e–superNLS

    Plasmid

    #232429

    Purpose

    Expression plasmid for the ABE8e base editor with superNLS

    Depositor

    Gil Westmeyer

    Article

    Geilenkeuser et al Cell. 2025 May 15;188(10):2637-2655.e31.

    Insert

    ABE8e–superNLS
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    April 10, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. pU6_HEK3+1T>A_(PP7-C4-Q1)

    Plasmid

    #232437

    Purpose

    pegRNA with optimized 3' modifications to facilitate a +1 T to A prime edit in the HEK3 locus

    Depositor

    Gil Westmeyer

    Article

    Geilenkeuser et al Cell. 2025 May 15;188(10):2637-2655.e31.

    Insert

    3'-PP7-tagged pegRNA for rd12 correction driven by human U6 promoter
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    April 10, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. pCMV-lyso-pHoenix

    Plasmid

    #70112

    Purpose

    Expression of lyso-pHoenix in mammalian cells for optogenetic acidification of lysosomes

    Depositor

    Christian Rosenmund

    Article

    Rost et al Nat Neurosci. 2015 Nov 9. doi: 10.1038/n

    Insert

    lyso-pHoenix (Cd63 Rat, Halorubrum sodomense, Entacmaea quadricolor, Aequorea victoria, Mouse)
    

    Use

    Tags

    Arch3, H+/K+ ATPase beta-subunit, HA-Tag, mKate2,…

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Nov. 11, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. pU6_rd6_pegRNA_(PP7-C4-Q1)

    Plasmid

    #232433

    Purpose

    pegRNA with optimized 3' modifications to correct the rd6 mutation

    Depositor

    Gil Westmeyer

    Article

    Geilenkeuser et al Cell. 2025 May 15;188(10):2637-2655.e31.

    Insert

    3'-PP7-tagged pegRNA for rd6 correction driven by human U6 promoter
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    April 10, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. pU6_rd6_nsgRNA(PP7)

    Plasmid

    #232434

    Purpose

    nsgRNA for PE3b correction of the rd6 mutation, contains a PP7 in the scaffold tetraloop

    Depositor

    Gil Westmeyer

    Article

    Geilenkeuser et al Cell. 2025 May 15;188(10):2637-2655.e31.

    Insert

    PP7-tagged nicking gRNA (PE3b) for rd6 correction driven by human U6 promoter
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    April 10, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. pU6_HEK3_nsgRNA(PP7)

    Plasmid

    #232444

    Purpose

    nsgRNA for PE3 facilitation of a +1 T to A prime edit on the HEK3 locus, contains a PP7 in the scaffold tetraloop

    Depositor

    Gil Westmeyer

    Article

    Geilenkeuser et al Cell. 2025 May 15;188(10):2637-2655.e31.

    Insert

    PP7-tagged nicking gRNA (PE3) for HEK3+1t>a edit driven by human U6 promoter
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    April 10, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. 3xflag-APEX2-LRRK2

    Plasmid

    #164622

    Purpose

    Expresses LRRK2 tagged with APEX2 and 3xFLAG

    Depositor

    Mark Cookson

    Article

    Bonet-Ponce et al Sci Adv. 2020 Nov 11;6(46). pii: 6/46/ea

    Insert

    LRRK2 (LRRK2 Human)
    

    Use

    Tags

    3xFLAG and APEX2

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Sept. 10, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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