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Showing: 1951 - 2000 of 4301 results

  6. pGL3Basic-ME.2/ApoEpromoter

    Plasmid
    #51436
    Purpose
    This plasmid is a luciferase-based reporter construct to measure the activity of the ApoE promoter fused to ME.2 enhancer
    Depositor
    Sohail Tavazoie
    Article
    Pencheva et al Cell. 2014 Feb 27;156(5):986-1001. doi:
    Insert
    APOE apolipoprotein E (APOE, ME2 Human)
    Use
    Luciferase
    Tags
    Expression
    Mammalian
    Mutation
    The ME.2 enhancer is fused upstream of the ApoE g…
    Promoter
    Available since
    Feb. 27, 2014
    Availability
    Academic Institutions and Nonprofits only
    51436-plasmid-map-sequence-id-177530

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  11. pmIL-6 mut AP-1+C/EBP

    Plasmid
    #61292
    Purpose
    drives luciferase from mouse IL-6 promoter with mutations in both AP-1 & C/EBP sites
    Depositor
    Gail Bishop
    Article
    Baccam et al J Immunol. 2003 Mar 15;170(6):3099-108.
    Insert
    IL-6 promoter (Il6 Mouse)
    Use
    Luciferase
    Tags
    Expression
    Mammalian
    Mutation
    Mutated both AP-1 binding site from TGAGTCT to TG…
    Promoter
    IL-6 promoter with mutant AP-1 and C/EBP binding …
    Available since
    May 4, 2015
    Availability
    Academic Institutions and Nonprofits only

  12. pFRLuc-CoV2-delStem1

    Plasmid
    #177616
    Purpose
    Dual luciferase reporter for SARS-CoV-2 programmed -1 ribosomal frameshifting. 3-nucleotide deletion in Stem 1 (negative control).
    Depositor
    Junjie Guo
    Article
    Sun et al Proc Natl Acad Sci U S A. 2021 Jun 29;11
    Insert
    SARS-CoV-2 FSE
    Use
    Luciferase
    Tags
    Expression
    Mammalian
    Mutation
    3-nucleotide (UAC) deletion in Stem 1
    Promoter
    Available since
    Dec. 10, 2021
    Availability
    Academic Institutions and Nonprofits only
    177616-plasmid-map-sequence-id-350042

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  15. pFRLuc-CoV2-FLucStop

    Plasmid
    #177617
    Purpose
    Dual luciferase reporter for SARS-CoV-2 programmed -1 ribosomal frameshifting. In-frame stop codon inserted after FLuc (negative control).
    Depositor
    Junjie Guo
    Article
    Sun et al Proc Natl Acad Sci U S A. 2021 Jun 29;11
    Insert
    SARS-CoV-2 FSE
    Use
    Luciferase
    Tags
    Expression
    Mammalian
    Mutation
    In-frame stop codon added between FLuc and FSE
    Promoter
    Available since
    Dec. 10, 2021
    Availability
    Academic Institutions and Nonprofits only
    177617-plasmid-map-sequence-id-350043

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  19. ssAAV-EF1a-FLuc-WPRE-HgHpA_bac_293

    Plasmid
    #118412
    Purpose
    Expresses firefly luciferase under the control of a strong ubiquitous promoter EF1a along with a WPRE cassette. Backbone is compatible with both baculoviral and human production methods of AAV.
    Depositor
    Nicole Paulk
    Article
    Rumachik et al Mol Ther Methods Clin Dev. 2020 May 22;1
    Insert
    Firefly luciferase
    Use
    AAV, Luciferase, and Synthetic Biology
    Tags
    Expression
    Insect and Mammalian
    Mutation
    Promoter
    EF1a
    Available since
    Nov. 20, 2019
    Availability
    Academic Institutions and Nonprofits only
    118412-plasmid-map-sequence-id-231800

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  23. pIS1 ATP2B1

    Plasmid
    #60788
    Purpose
    Luciferase reporter to measure miR-155 mediated differential repression. Contains ATP2B1 3' UTR and wild-type miR-155 sites
    Depositor
    David Bartel
    Article
    Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi
    Insert
    ATP2B1 3'UTR and wild-type miR-155 binding site (ATP2B1 Human)
    Use
    Luciferase
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    thymidine kinase (HSV-TK promoter)
    Available since
    Oct. 21, 2014
    Availability
    Academic Institutions and Nonprofits only
    60788-plasmid-map-sequence-id-97788

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  24. pIS1 INSIG2

    Plasmid
    #60798
    Purpose
    Luciferase reporter to measure miR-155 mediated differential repression. Contains INSIG2 3' UTR and wild-type miR-155 sites
    Depositor
    David Bartel
    Article
    Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi
    Insert
    INSIG2 3'UTR and wild-type miR-155 binding site (INSIG2 Human)
    Use
    Luciferase
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    thymidine kinase (HSV-TK promoter)
    Available since
    Oct. 20, 2014
    Availability
    Academic Institutions and Nonprofits only
    60798-plasmid-map-sequence-id-97809

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  26. pIS1 mPELO

    Plasmid
    #60805
    Purpose
    Luciferase reporter to measure miR-155 mediated differential repression. Contains PELO 3' UTR and mutated miR-155 sites
    Depositor
    David Bartel
    Article
    Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi
    Insert
    PELO 3'UTR and mutated miR-155 binding site (PELO Human)
    Use
    Luciferase
    Tags
    Expression
    Mammalian
    Mutation
    mutated miR-155 binding site
    Promoter
    thymidine kinase (HSV-TK promoter)
    Available since
    Oct. 20, 2014
    Availability
    Academic Institutions and Nonprofits only
    60805-plasmid-map-sequence-id-97816

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  27. pIS1 mATP2B1

    Plasmid
    #60789
    Purpose
    Luciferase reporter to measure miR-155 mediated differential repression. Contains ATP2B1 3' UTR and mutated miR-155 sites
    Depositor
    David Bartel
    Article
    Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi
    Insert
    ATP2B1 3'UTR and mutated miR-155 binding site (ATP2B1 Human)
    Use
    Luciferase
    Tags
    Expression
    Mammalian
    Mutation
    mutated miR-155 binding site
    Promoter
    thymidine kinase (HSV-TK promoter)
    Available since
    Oct. 20, 2014
    Availability
    Academic Institutions and Nonprofits only
    60789-plasmid-map-sequence-id-97792

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  28. pGL3-Enhancer-ZC3H12D_PromoterMUT

    Plasmid
    #153068
    Purpose
    ZC3H12D promoter region carrying mutations in BHLHE40 binding sites, cloned upstream of luciferase reporter
    Depositor
    Silvia Monticelli
    Article
    Emming et al Nat Immunol. 2020 Apr;21(4):388-399. doi
    Insert
    ZC3H12D promoter region mutated in BHLHE40 binding sites (ZC3H12D Human)
    Use
    Luciferase
    Tags
    Expression
    Mammalian
    Mutation
    Mutagenesis to disrupt 3 BHLHE40 binding sites. N…
    Promoter
    None
    Available since
    Sept. 15, 2020
    Availability
    Academic Institutions and Nonprofits only
    153068-plasmid-map-sequence-id-304889

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  30. pIS1 LMBRD2

    Plasmid
    #60800
    Purpose
    Luciferase reporter to measure miR-155 mediated differential repression. Contains LMBRD2 3' UTR and wild-type miR-155 sites
    Depositor
    David Bartel
    Article
    Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi
    Insert
    LMBRD2 3'UTR and wild-type miR-155 binding site (LMBRD2 Human)
    Use
    Luciferase
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    thymidine kinase (HSV-TK promoter)
    Available since
    May 18, 2015
    Availability
    Academic Institutions and Nonprofits only
    60800-plasmid-map-sequence-id-112557

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  31. pAM4663

    Plasmid
    #85126
    Purpose
    NSIII -Cm-PkaiB-luc+ (firefly) vector constructed by seamless cloning with Cm casette codon optimized for S7942. PkaiB-luc+ amplified from pAM2105.
    Depositor
    Susan Golden
    Article
    Chang et al Science. 2015 Jul 17;349(6245):324-8. do
    Insert
    PkaiB-luciferase
    Use
    Tags
    Expression
    Bacterial
    Mutation
    Promoter
    Available since
    May 31, 2017
    Availability
    Academic Institutions and Nonprofits only
    85126-plasmid-map-sequence-id-180127

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  32. pIS1 mINSIG2

    Plasmid
    #60799
    Purpose
    Luciferase reporter to measure miR-155 mediated differential repression. Contains INSIG2 3' UTR and mutated miR-155 sites
    Depositor
    David Bartel
    Article
    Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi
    Insert
    INSIG2 3'UTR and mutated miR-155 binding site (INSIG2 Human)
    Use
    Luciferase
    Tags
    Expression
    Mammalian
    Mutation
    mutated miR-155 binding site
    Promoter
    thymidine kinase (HSV-TK promoter)
    Available since
    May 18, 2015
    Availability
    Academic Institutions and Nonprofits only
    60799-plasmid-map-sequence-id-112562

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  33. pIS1 mELOVL6

    Plasmid
    #60791
    Purpose
    Luciferase reporter to measure miR-155 mediated differential repression. Contains ELOVL6 3' UTR and mutated miR-155 sites
    Depositor
    David Bartel
    Article
    Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi
    Insert
    ELOVL6 3'UTR and mutated miR-155 binding site (ELOVL6 Human)
    Use
    Luciferase
    Tags
    Expression
    Mammalian
    Mutation
    mutated miR-155 binding site
    Promoter
    thymidine kinase (HSV-TK promoter)
    Available since
    May 18, 2015
    Availability
    Academic Institutions and Nonprofits only
    60791-plasmid-map-sequence-id-112566

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  34. pIS1 mLMBRD2

    Plasmid
    #60801
    Purpose
    Luciferase reporter to measure miR-155 mediated differential repression. Contains LMBRD2 3' UTR and mutated miR-155 sites
    Depositor
    David Bartel
    Article
    Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi
    Insert
    LMBRD2 3'UTR and mutated miR-155 binding site (LMBRD2 Human)
    Use
    Luciferase
    Tags
    Expression
    Mammalian
    Mutation
    mutated miR-155 binding site
    Promoter
    thymidine kinase (HSV-TK promoter)
    Available since
    May 18, 2015
    Availability
    Academic Institutions and Nonprofits only
    60801-plasmid-map-sequence-id-112558

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  37. pIS1 ELOVL6

    Plasmid
    #60790
    Purpose
    Luciferase reporter to measure miR-155 mediated differential repression. Contains ELOVL6 3' UTR and wild-type miR-155 sites
    Depositor
    David Bartel
    Article
    Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi
    Insert
    ELOVL6 3'UTR and wild-type miR-155 binding site (ELOVL6 Human)
    Use
    Luciferase
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    thymidine kinase (HSV-TK promoter)
    Available since
    Oct. 20, 2014
    Availability
    Academic Institutions and Nonprofits only
    60790-plasmid-map-sequence-id-97799

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  38. pIS1 LPIN1

    Plasmid
    #60802
    Purpose
    Luciferase reporter to measure miR-155 mediated differential repression. Contains LPIN1 3' UTR and wild-type miR-155 sites
    Depositor
    David Bartel
    Article
    Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi
    Insert
    LPIN1 3'UTR and wild-type miR-155 binding site (LPIN1 Human)
    Use
    Luciferase
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    thymidine kinase (HSV-TK promoter)
    Available since
    May 18, 2015
    Availability
    Academic Institutions and Nonprofits only
    60802-plasmid-map-sequence-id-112564

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  39. pIS1 mLPIN1

    Plasmid
    #60803
    Purpose
    Luciferase reporter to measure miR-155 mediated differential repression. Contains LPIN1 3' UTR and mutated miR-155 sites
    Depositor
    David Bartel
    Article
    Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi
    Insert
    LPIN1 3'UTR and mutated miR-155 binding site (LPIN1 Human)
    Use
    Luciferase
    Tags
    Expression
    Mammalian
    Mutation
    mutated miR-155 binding site
    Promoter
    thymidine kinase (HSV-TK promoter)
    Available since
    Oct. 20, 2014
    Availability
    Academic Institutions and Nonprofits only
    60803-plasmid-map-sequence-id-97814

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  40. pIS1 PELO

    Plasmid
    #60804
    Purpose
    Luciferase reporter to measure miR-155 mediated differential repression. Contains PELO 3' UTR and wild-type miR-155 sites
    Depositor
    David Bartel
    Article
    Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi
    Insert
    PELO 3'UTR and wild-type miR-155 binding site (PELO Human)
    Use
    Luciferase
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    thymidine kinase (HSV-TK promoter)
    Available since
    Oct. 20, 2014
    Availability
    Academic Institutions and Nonprofits only
    60804-plasmid-map-sequence-id-97815

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  43. pIS1 EPAS1

    Plasmid
    #60792
    Purpose
    Luciferase reporter to measure miR-155 mediated differential repression. Contains EPAS1 3' UTR and wild-type miR-155 sites
    Depositor
    David Bartel
    Article
    Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi
    Insert
    EPAS1 3'UTR and wild-type miR-155 binding site (EPAS1 Human)
    Use
    Luciferase
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    thymidine kinase (HSV-TK promoter)
    Available since
    Oct. 20, 2014
    Availability
    Academic Institutions and Nonprofits only
    60792-plasmid-map-sequence-id-97802

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  46. pGL3-noSV40-humanEC1.45_min1-2_4XEboxMutant

    Plasmid
    #215026
    Purpose
    Firefly luciferase enhancer reporter plasmid with minimal enhancer regions 1 and 2 (min1 and min2) from SOX9 enhancer cluster EC1.45 with E-boxes mutated
    Depositor
    Joanna Wysocka
    Article
    Kim et al Cell. 2024 Feb 1;187(3):692-711.e26. doi
    Insert
    Minimal enhancer regions 1 and 2 (min1 and min2) from SOX9 enhancer cluster EC1.45 with E-boxes mutated
    Use
    Luciferase
    Tags
    Expression
    Mutation
    4X E-box mutations within Coordinator motifs
    Promoter
    SV40
    Available since
    March 20, 2024
    Availability
    Academic Institutions and Nonprofits only
    215026-plasmid-map-sequence-id-425844

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Showing: 1951 - 2000 of 4301 results