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We narrowed to 1,372 results for: ABE8e

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Showing: 781 - 800 of 1372 results

  3. pME270

    Plasmid
    #238067
    Purpose
    Expresses ME-ABE ABE7.10-HRHSK with SpCas9 (NG)
    Depositor
    Alexis Komor
    Publication
    Evanoff et al Nat Biotechnol. 2026 Mar 18. doi: 10.103
    Insert
    TadA*7.10(L36H/L51R/Y123H/C146S/N157K)-m_SpnCas9(D10A)
    Use
    CRISPR
    Tags
    SV40 bpNLS and SV40 bpNLS-P2A-mCherry
    Expression
    Mammalian
    Mutation
    TadA modifications include L36H, L51R, Y123H, C14…
    Available since
    Jan. 9, 2026
    Availability
    Academic Institutions and Nonprofits only
    238067-plasmid-map-sequence-id-472657

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  6. pCMV-ABE8.8m-SpG-P2A-EGFP (BKS965)

    Plasmid
    #242652
    Purpose
    CMV promoter expression plasmid for human codon optimized ABE8.8m A-to-G base editor with SpG(D10A) and P2A-EGFP
    Depositor
    Benjamin Kleinstiver
    Publication
    Alves et al Nat Biomed Eng. 2025 Sep 11:10.1038/s415
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    pCMV-ABE8.8m-SpG-P2A-EGFP
    Use
    CRISPR
    Tags
    BPNLS and BPNLS-3xFLAG-P2A-EGFP
    Expression
    Mammalian
    Mutation
    ABE8.8 mutations in TadA, SpG mutations in SpCas9…
    Promoter
    CMV and T7
    Available since
    Oct. 9, 2025
    Availability
    Academic Institutions and Nonprofits only
    242652-plasmid-map-sequence-id-488985

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  7. Tad-CBE(CCC5)

    Plasmid
    #235073
    Purpose
    Expresses Tad-CBE(CCC5) in mammalian cells.
    Depositor
    Weixin Tang
    Publication
    Wu et al Nat Biotechnol. 2025 Jul 7:10.1038/s4158
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    Tad-CBE(CCC5)-SpCas9 D10A
    Use
    CRISPR
    Tags
    2xUGI, bpNLS and bpNLS
    Expression
    Mammalian
    Available since
    July 14, 2025
    Availability
    Academic Institutions and Nonprofits only
    235073-plasmid-map-sequence-id-469793

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  8. Tad-CBE(CCG3)

    Plasmid
    #235074
    Purpose
    Expresses Tad-CBE(CCG3) in mammalian cells.
    Depositor
    Weixin Tang
    Publication
    Wu et al Nat Biotechnol. 2025 Jul 7:10.1038/s4158
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    Tad-CBE(CCG3)-SpCas9 D10A
    Use
    CRISPR
    Tags
    2xUGI, bpNLS and bpNLS
    Expression
    Mammalian
    Available since
    July 14, 2025
    Availability
    Academic Institutions and Nonprofits only
    235074-plasmid-map-sequence-id-468470

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  9. gTBEv4

    Plasmid
    #220620
    Purpose
    vector for encoding an engineered glycosylase-based thymine (T) base editor (gTBEv4) driven by EF1a promoter, guide RNAs compatible with SpCas9 driven by hU6, mCherry driven by CBh promoter
    Depositor
    Huawei Tong
    Publication
    Tong et al Nat Commun. 2024 Jun 8;15(1):4897. doi:
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    nSpCas9(Nterm)-XTEN-hUNG2-XTEN-Cas9(Cterm)
    Expression
    Mammalian
    Mutation
    hUNG2(del1-88;Y156A,A214T,Q259A,Y284D), SpCas9(D1…
    Promoter
    hU6, EF1a
    Available since
    June 21, 2024
    Availability
    Academic Institutions and Nonprofits only
    220620-plasmid-map-sequence-id-436970

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  10. nCas9-SpRY_P2A-mCherry

    Plasmid
    #219935
    Purpose
    Mammalian expression of SpRY-nCas9 with P2A-mCherry marker for use with MOBE systems
    Depositor
    Alexis Komor
    Publication
    Cowan et al Nat Biotechnol. 2024 May 21. doi: 10.103
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    Sp-nCas9(D10A)-SpRY_P2A-mCherry
    Use
    CRISPR
    Tags
    SV40 bpNLS and SV40 bpNLS-P2A-mCherry
    Expression
    Mammalian
    Mutation
    nCas9(D10A)
    Promoter
    CMV
    Available since
    June 5, 2024
    Availability
    Academic Institutions and Nonprofits only
    219935-plasmid-map-sequence-id-435502

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  14. pCMV-dCas12a-ABE7

    Plasmid
    #193644
    Purpose
    Expression of base editor dCas12a-ABE7 in mammalian cells for base editing, along with non-fused EGFP fluorescence
    Depositor
    Liangxue Lai
    Publication
    Chen et al Commun Biol. 2022 Nov 2;5(1):1163. doi:
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    dLbCas12a-TadA-TadA*7.10, EGFP
    Expression
    Mammalian
    Promoter
    CMV
    Available since
    Feb. 20, 2024
    Availability
    Academic Institutions and Nonprofits only
    193644-plasmid-map-sequence-id-421946

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  15. ABE-RA3.0

    Plasmid
    #208301
    Purpose
    Expresses ABE-RA3.0 in mammalian cells
    Depositor
    Weixin Tang
    Publication
    Xiao et al Nat Biotechnol. 2024 Jan 2. doi: 10.1038
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    TadA-RA3.0-SpCas9 D10A
    Expression
    Mammalian
    Mutation
    E27D, P48A, R51H, I76F, D108G, K110R, H122R, M126…
    Available since
    Jan. 2, 2024
    Availability
    Academic Institutions and Nonprofits only
    208301-plasmid-map-sequence-id-410368

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  16. A3Bmax

    Plasmid
    #207167
    Purpose
    Express full-length human A3B in a BE4max-based base editor
    Depositor
    Reuben Harris
    Publication
    Rieffer et al CRISPR J. 2023 Oct;6(5):430-446. doi: 10
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-like 3B (APOBEC3B Human)
    Tags
    NLS and NLS, 6x His
    Expression
    Mammalian
    Promoter
    CMV
    Available since
    Nov. 6, 2023
    Availability
    Academic Institutions and Nonprofits only
    207167-plasmid-map-sequence-id-409392

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  18. pDV02_linear_entry_TagBFP-2A-MCS-2A-mNeonGreen

    Plasmid
    #200401
    Purpose
    Entry vector for open-loop ADAR-based RNA sensors. Expresses TagBFP constitutively. Expresses mNeonGreen upon target detection
    Depositor
    James Collins
    Publication
    Gayet et al Nat Commun. 2023 Mar 11;14(1):1339. doi:
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    Open-loop DART VADAR sensor entry cassette
    Use
    Synthetic Biology
    Expression
    Mammalian
    Available since
    June 30, 2023
    Availability
    Academic Institutions and Nonprofits only
    200401-plasmid-map-sequence-id-396795

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  19. pDV05.1_pEF1a-iRFP720_frameshifted

    Plasmid
    #200408
    Purpose
    Expresses a mutant iRFP720 mRNA constitutively in mammalian cells. A frameshift deletion in the ORF (compared to pDV05.0) prevents the correct translation of the fluorescent protein
    Depositor
    James Collins
    Publication
    Gayet et al Nat Commun. 2023 Mar 11;14(1):1339. doi:
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    iRFP720 (frameshift mutant)
    Use
    Synthetic Biology
    Expression
    Mammalian
    Available since
    June 30, 2023
    Availability
    Academic Institutions and Nonprofits only
    200408-plasmid-map-sequence-id-396809

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Showing: 781 - 800 of 1372 results