We narrowed to 1,647 results for: Tyr

1. MERTK gRNA (BRDN0001144964)

   Plasmid

   #76445

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human MERTK

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   MERTK (MERTK Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. MERTK gRNA (BRDN0001146205)

   Plasmid

   #76446

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human MERTK

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   MERTK (MERTK Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pDEST-ERBB3-v2

   Plasmid

   #154894

   Purpose

   Expresses ERBB3 (a.k.a HER3) fused to Venus fragment 2 (v2) for use in bimolecular fluorescence complementation (BiFC) assays

   Depositor

   Johanna Ivaska

   Article

   Al-Akhrass et al Oncogene. 2021 Feb;40(7):1300-1317. doi:

   Insert

   ERBB3 (ERBB3 Human)
   

   Use

   Tags

   Venus fragment 2 (v2)

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   July 27, 2020

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. sgALK(A)

   Plasmid

   #85562

   Purpose

   Expresses sgRNA targeting human ALK around codon F1174

   Depositor

   Luca Grumolato

   Article

   Guernet et al Mol Cell. 2016 Aug 4;63(3):526-38. doi:

   Insert

   anaplastic lymphoma receptor tyrosine kinase (ALK Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Feb. 8, 2017

   Availability

   Academic Institutions and Nonprofits only

5. pcDNA4-His-Max-A-PQBP1-Y65C

   Plasmid

   #25803

   Depositor

   Marius Sudol

   Article

   Tapia et al J Biol Chem. 2010 Jun 18;285(25):19391-4

   Insert

   PQBP1 with Y65C mutation (PQBP1 Human)
   

   Use

   Tags

   His and Xpress

   Expression

   Mammalian

   Mutation

   Tyrosine 65 within the WW domain of PQBP1 is chan…

   Promoter

   Available since

   July 21, 2010

   Availability

   Academic Institutions and Nonprofits only

6. EPHA4 gRNA (BRDN0001144994)

   Plasmid

   #76666

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human EPHA4

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   EPHA4 (EPHA4 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. EPHA4 gRNA (BRDN0001146799)

   Plasmid

   #76667

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human EPHA4

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   EPHA4 (EPHA4 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. Flag-KLF6-4D (1054)

   Plasmid

   #49490

   Purpose

   expresses human Flag tagged KLF6 with 4D mutation

   Depositor

   Scott Friedman

   Article

   Lang et al Oncogene. 2012 Oct 22. doi: 10.1038/onc.

   Insert

   KFL6-4D (KLF6 Human)
   

   Use

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   three serines and one tyrosine mutated to aspart…

   Promoter

   CMV

   Available since

   Feb. 18, 2014

   Availability

   Academic Institutions and Nonprofits only

9. pDEST53-LRRK2-3XKD-Y1699C

   Plasmid

   #25051

   Depositor

   Mark Cookson

   Article

   Greggio et al Neurobiol Dis. 2006 Aug . 23(2):329-41.

   Insert

   LRRK2 (LRRK2 Human)
   

   Use

   Tags

   GFP

   Expression

   Mammalian

   Mutation

   "Kinase Dead" Lysine 1906 mutated to A…

   Promoter

   Available since

   June 29, 2010

   Availability

   Academic Institutions and Nonprofits only

10. sgALK(B)

    Plasmid

    #85563

    Purpose

    Expresses sgRNA targeting human ALK around codon F1174

    Depositor

    Luca Grumolato

    Article

    Guernet et al Mol Cell. 2016 Aug 4;63(3):526-38. doi:

    Insert

    anaplastic lymphoma receptor tyrosine kinase (ALK Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Feb. 8, 2017

    Availability

    Academic Institutions and Nonprofits only

11. EPHB2 gRNA (BRDN0001146273)

    Plasmid

    #77545

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human EPHB2

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    EPHB2 (EPHB2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. EPHB2 gRNA (BRDN0001147469)

    Plasmid

    #77546

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human EPHB2

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    EPHB2 (EPHB2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. EPHB2 gRNA (BRDN0001147792)

    Plasmid

    #77547

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human EPHB2

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    EPHB2 (EPHB2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. EPHB2 gRNA (BRDN0001147198)

    Plasmid

    #77548

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human EPHB2

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    EPHB2 (EPHB2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. RCAS-Neu HA SIINFEKL

    Plasmid

    #125832

    Purpose

    Retroviral expression of rat Neu cDNA

    Depositor

    Yi Li

    Article

    Du et al Proc Natl Acad Sci U S A. 2006 Nov 14;10

    Insert

    Neu (Erbb2 Rat)
    

    Use

    Retroviral

    Tags

    2x HA and SIINFEKL

    Expression

    Mammalian

    Mutation

    Val to Glu point mutation of codon 664 and trunca…

    Promoter

    Available since

    July 23, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pGEX-4T-3-GST-Tev-Af1521(K35E/Y145R)-myc

    Plasmid

    #196241

    Purpose

    N-terminal GST fusion of Af1521(K35E/Y145R) with a TEV protease site located between the GST tag and Af1521 and a myc tag on the C terminus

    Depositor

    Robert Sobol

    Article

    Al-Rahahleh et al DNA Repair (Amst). 2025 Jun;150:103845.

    Insert

    N-terminal GST fusion of Af1521(K35E/Y145R) with a TEV protease site between GST and Af1521 encoding a C-terminal myc tag
    

    Use

    Tags

    GST tag and myc tag

    Expression

    Bacterial

    Mutation

    amino acid 35 lysine is replaced with glutamic ac…

    Promoter

    Available since

    Aug. 8, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pcDNA3.1-PDGFRA-V561D-V5/HIS

    Plasmid

    #234762

    Purpose

    Expression of the V561D mutant variant of human PDGFRA, which is associated with Gastrointestinal Stromal Tumor and GIST-Plus Syndrome, , constantly activated

    Depositor

    Pavel Krejčí

    Article

    Gudernova et al Oncotarget. 2017 Nov 27;8(65):109319-109

    Insert

    PDGFRA-V561D receptor tyrosine kinase, full length (PDGFRA Human)
    

    Use

    Tags

    V5/His

    Expression

    Mammalian

    Mutation

    V561D substitution

    Promoter

    CMV

    Available since

    April 15, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pcDNA3.1-PDGFRA-P577S-V5/HIS

    Plasmid

    #234760

    Purpose

    Expression of the P577S mutant variant of human PDGFRA, which might be associated with Melanoma

    Depositor

    Pavel Krejčí

    Article

    Gudernova et al Elife. 2017 Feb 15;6. pii: e21536. doi:

    Insert

    PDGFRA-P577S receptor tyrosine kinase, full length (PDGFRA Human)
    

    Use

    Tags

    V5/His

    Expression

    Mammalian

    Mutation

    P577S substitution

    Promoter

    CMV

    Available since

    April 15, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pcDNA3.1-PDGFRA-R487L-V5/HIS

    Plasmid

    #234761

    Purpose

    Expression of the R487L mutant variant of human PDGFRA, which might be associated with Gastrointestinal Stromal Tumor

    Depositor

    Pavel Krejčí

    Article

    Gudernova et al Elife. 2017 Feb 15;6. pii: e21536. doi:

    Insert

    PDGFRA-R487L receptor tyrosine kinase, full length (PDGFRA Human)
    

    Use

    Tags

    V5/His

    Expression

    Mammalian

    Mutation

    R487L substitution

    Promoter

    CMV

    Available since

    April 15, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pcDNA3.1-PDGFRA-D842V-V5/HIS

    Plasmid

    #234763

    Purpose

    Expression of the D842V mutant variant of human PDGFRA, which is associated with Gastrointestinal Stromal Tumor, constantly activated

    Depositor

    Pavel Krejčí

    Article

    Gudernova et al Oncotarget. 2017 Nov 27;8(65):109319-109

    Insert

    PDGFRA-D842V receptor tyrosine kinase, full length (PDGFRA Human)
    

    Use

    Tags

    V5/His

    Expression

    Mammalian

    Mutation

    D842V substitution

    Promoter

    CMV

    Available since

    April 15, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. pcDNA3.1-PDGFRA-G853D-V5/HIS

    Plasmid

    #234757

    Purpose

    Expression of the G853D mutant variant of human PDGFRA, which might be associated with Melanoma

    Depositor

    Pavel Krejčí

    Article

    Gudernova et al Elife. 2017 Feb 15;6. pii: e21536. doi:

    Insert

    PDGFRA-G853D receptor tyrosine kinase, full length (PDGFRA Human)
    

    Use

    Tags

    V5/His

    Expression

    Mammalian

    Mutation

    G853D substitution

    Promoter

    CMV

    Available since

    April 15, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. pcDNA3.1-PDGFRA-T674I-V5/HIS

    Plasmid

    #234756

    Purpose

    Expression of the T674I mutant variant of human PDGFRA, which is associated with Idiopathic Hypereosinophilic Syndrome, resistant to imatinib

    Depositor

    Pavel Krejčí

    Article

    Gudernova et al Elife. 2017 Feb 15;6. pii: e21536. doi:

    Insert

    PDGFRA-T674I receptor tyrosine kinase, full length (PDGFRA Human)
    

    Use

    Tags

    V5/His

    Expression

    Mammalian

    Mutation

    T674I substitution

    Promoter

    CMV

    Available since

    April 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. pcDNA3.1-PDGFRA-K627M-V5/HIS

    Plasmid

    #234755

    Purpose

    Expression of the K627M kinase defective mutant variant of human PDGFRA

    Depositor

    Pavel Krejčí

    Article

    Gudernova et al Elife. 2017 Feb 15;6. pii: e21536. doi:

    Insert

    PDGFRA-K627M receptor tyrosine kinase, full length (PDGFRA Human)
    

    Use

    Tags

    V5/His

    Expression

    Mammalian

    Mutation

    K627M substitution

    Promoter

    CMV

    Available since

    March 25, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. Str-KDEL_CD63YA-SBP-EGFP

    Plasmid

    #222327

    Purpose

    Synchronize the trafficking of CD63YA from the ER.

    Depositor

    Franck Perez

    Article

    Mathieu et al Nat Commun. 2021 Jul 19;12(1):4389. doi:

    Insert

    Streptavidin-KDEL and CD63-Y235A fused to SBP-EGFP (CD63 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Tyr235 to Ala

    Promoter

    CMV

    Available since

    Feb. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. CamKII-LGI1-Y433A-pHluorin

    Plasmid

    #185541

    Purpose

    Expresses mutant Y433A LGI1-pHluorin under the CamKII promoter

    Depositor

    Jaime de Juan-Sanz

    Article

    Cuhadar et al Cell Rep. 2024 May 28;43(5):114186. doi:

    Insert

    LGI1 (Lgi1 Rat)
    

    Use

    Lentiviral

    Tags

    pHluorin

    Expression

    Mammalian

    Mutation

    changed tyrosine 433 for alanine

    Promoter

    CamKII

    Available since

    May 3, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. DDR2 gRNA (BRDN0001147364)

    Plasmid

    #77972

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human DDR2

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    DDR2 (DDR2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. DDR2 gRNA (BRDN0001147484)

    Plasmid

    #77973

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human DDR2

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    DDR2 (DDR2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. DDR2 gRNA (BRDN0001147906)

    Plasmid

    #77974

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human DDR2

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    DDR2 (DDR2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. DDR2 gRNA (BRDN0001487155)

    Plasmid

    #77975

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human DDR2

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    DDR2 (DDR2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. EPHA3 gRNA (BRDN0001148513)

    Plasmid

    #76744

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human EPHA3

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    EPHA3 (EPHA3 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge