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We narrowed to 15,279 results for: grn

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Showing: 10501 - 10520 of 15279 results

  4. pCRISPEY-GAL-Kan-ADE2

    Plasmid
    #232105
    Purpose
    Expresses galactose-inducible CRISPR guide RNA and repair template for creating a frameshift mutation in ADE2 gene of yeast.
    Depositor
    Jeffrey Lewis
    Publication
    Stuecker et al G3 (Bethesda). 2025 Aug 4:jkaf175. doi:
    Insert
    ADE2 gRNA and repair template
    Use
    CRISPR
    Expression
    Yeast
    Mutation
    Repair template introduces C at nt 466 of ADE2 to…
    Promoter
    GAL7
    Available since
    Feb. 21, 2025
    Availability
    Academic Institutions and Nonprofits only
    232105-plasmid-map-sequence-id-462309

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  5. pBPK1520-SNCA-A53T-ng

    Plasmid
    #181739
    Purpose
    Transiently expressing a nicking sgRNA to facilitate the introduction of SNCA-A53T mutation in PE3 approach
    Depositor
    Dirk Hockemeyer
    Publication
    Li et al Elife. 2022 Sep 7;11:e79208. doi: 10.755
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    Prime editing ngRNA for SNCA-A53T (SNCA Human)
    Use
    CRISPR
    Expression
    Mammalian
    Promoter
    Human U6
    Available since
    Sept. 8, 2022
    Availability
    Academic Institutions and Nonprofits only
    181739-plasmid-map-sequence-id-356616

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  6. pBPK1520-SNCA-A30P-ng

    Plasmid
    #180018
    Purpose
    Transiently expressing a nicking sgRNA to facilitate the introduction of SNCA-A30P mutation in PE3 approach
    Depositor
    Dirk Hockemeyer
    Publication
    Li et al Elife. 2022 Sep 7;11:e79208. doi: 10.755
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    Prime editing ngRNA for SNCA-A30P (SNCA Human)
    Use
    CRISPR
    Expression
    Mammalian
    Promoter
    Human U6
    Available since
    Sept. 8, 2022
    Availability
    Academic Institutions and Nonprofits only
    180018-plasmid-map-sequence-id-354116

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  7. B-evoSpCas9

    Plasmid
    #126765
    Purpose
    Expression plasmid for human codon-opt. increased fidelity Blackjack-evoSpCas9 (w/o U6-sgRNA). Cleaves both 20nt and 5'-extended 21nt spacer containing sgRNAs with higher fidelity than evoSpCas9.
    Depositor
    Ervin Welker
    Publication
    Kulcsar et al Nat Commun. 2020 Mar 6;11(1):1223. doi:
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    B-evoSpCas9
    Use
    CRISPR
    Tags
    3xFLAG and NLS
    Expression
    Mammalian
    Mutation
    M495V; Y515N; K526E; R661Q; amino acids 1005-1013…
    Promoter
    CBh
    Available since
    March 6, 2020
    Availability
    Academic Institutions and Nonprofits only
    126765-plasmid-map-sequence-id-410921

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  8. LADL Bridge + Promoter Only Target

    Plasmid
    #127669
    Purpose
    Encodes for CRY2-HA and mCherry proteins expressed from the EF1a promoter as well as 2 gRNAs targeting the Zfp462 promoter expressed from their individual hU6 promoters
    Depositor
    Jennifer Phillips-Cremins
    Publication
    Kim et al Nat Methods. 2019 Jun 24. pii: 10.1038/s
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    CRY2-HA-2A-mCherry and gRNAs 115 and 117
    Use
    CRISPR
    Tags
    HA
    Expression
    Mammalian
    Promoter
    EF1a and hU6
    Available since
    July 11, 2019
    Availability
    Academic Institutions and Nonprofits only
    127669-plasmid-map-sequence-id-249167

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  9. PLL5.0-Anillin ShRNA-Cherry-AnillinA740D, E758K

    Plasmid
    #187273
    Purpose
    Lentiviral expression of shRNA targeting Anillin + reconstitution of Anillin A740D,E758K
    Depositor
    Alpha Yap
    Publication
    Budnar et al Dev Cell. 2019 Jun 17;49(6):894-906.e12.
    Insert
    Anillin ,hsAnillin, Entrez Gene ANLN (a.k.a. FSGS8, Scraps, scra) (ANLN Human)
    Use
    Lentiviral
    Tags
    mCherry
    Mutation
    Anillin A740D, E758K
    Promoter
    U6, CMV
    Available since
    Sept. 26, 2022
    Availability
    Academic Institutions and Nonprofits only
    187273-plasmid-map-sequence-id-373245

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  14. pInducer20_SLC38A2_wt

    Plasmid
    #156182
    Purpose
    Dox-inducible expression of sgRNA-resistant SLC38A2 wild-type cDNA.
    Depositor
    Alec Kimmelman
    Publication
    Parker et al Cancer Discov. 2020 Apr 27. pii: 2159-82
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    SLC38A2 (SLC38A2 Human)
    Expression
    Mammalian
    Mutation
    Silent mutations to prevent targeting by sgRNA: T…
    Promoter
    TRE
    Available since
    Aug. 20, 2020
    Availability
    Academic Institutions and Nonprofits only
    156182-plasmid-map-sequence-id-309019

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Showing: 10501 - 10520 of 15279 results