We narrowed to 18,297 results for: MUT

1. pAAV-EF1α-Flex/3'USS-ChRWR/Venus(ATG mut)

   Plasmid

   #197891

   Purpose

   Can be used to generate AAV virus that will express ChRWR/Venus in the presence of Cre and the leakage expression is significantly reduced without Cre

   Depositor

   Kazuto Kobayashi

   Article

   Matsushita et al Cell Rep Methods. 2023 Jan 18;3(2):10039

   Insert

   ChRWR/Venus
   

   Use

   AAV

   Mutation

   N/A

   Promoter

   EF1a

   Available Since

   March 15, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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2. pCAG-GST-hFIP200(Delta641-779, 1363-1370Mut)-MBP

   Plasmid

   #190039

   Purpose

   Expression of FIP200 mutant

   Depositor

   James Hurley

   Article

   Shi et al Elife. 2020 Aug 10;9. pii: 59099. doi: 1

   Insert

   FIP200 (RB1CC1 Human)
   

   Tags

   GST and MBP

   Expression

   Mammalian

   Mutation

   (641-779)deletion & 1363 RDKDLIES 1370 to GSS…

   Promoter

   CMV

   Available Since

   Nov. 8, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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3. pMSCV-IRES-GFP-dog-Caspase-1/4a-triple mutant-H342D_K345M_K379T

   Plasmid

   #183364

   Purpose

   Stable expression of mammalian inflammatory caspase gene in mammalian cells by retroviral transduction

   Depositor

   Jonathan Kagan

   Article

   Devant et al Sci Immunol. 2021 Aug 10;6(62). doi: 10.

   Insert

   Caspase-1/4a (CASP4 Canis lupus familiaris)
   

   Use

   Retroviral

   Tags

   Myc

   Mutation

   H342D_K345M_K379T

   Promoter

   MESV

   Available Since

   May 5, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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4. MSCV-mouse Mdm2 mutant M3 (399-489)-IRES-GFP

   Plasmid

   #180490

   Purpose

   Role of Mdm2 variants in tumorigenesis

   Depositor

   Martine Roussel

   Article

   Dang et al Cancer Res. 2002 Feb 15;62(4):1222-30.

   Inserts

   Mouse Mdm2 mutant
   Mouse Mdm2 mutant
   

   Expression

   Mammalian

   Mutation

   399-489

   Promoter

   MSCV

   Available Since

   March 29, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. MSCV-mouse Mdm2 mutant M2 (299-489)-IRES-GFP

   Plasmid

   #180489

   Purpose

   Role of Mdm2 variants in tumorigenesis

   Depositor

   Martine Roussel

   Article

   Dang et al Cancer Res. 2002 Feb 15;62(4):1222-30.

   Insert

   Mouse Mdm2 mutant
   

   Use

   Retroviral

   Expression

   Mammalian

   Mutation

   299-489

   Promoter

   MSCV

   Available Since

   March 29, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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6. pLV-EGFP-PolB-(K35A/K68A/K72A)-PAMmut-Hygro

   Plasmid

   #176089

   Purpose

   EGFP fused the N-terminus of POLB containing the mutations Lys35Ala, Lys68Ala, and Lys72Ala, a mutation in the PAM site used by POLB gRNA1 & a hygromycin resistance cassette

   Depositor

   Robert Sobol

   Article

   Koczor et al Cell Rep. 2021 Nov 2;37(5):109917. doi:

   Insert

   PolB (POLB Human)
   

   Use

   Lentiviral

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   Mutations in Lys35 to Ala, Lys68 to Ala, and Lys7…

   Promoter

   CMV

   Available Since

   Jan. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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7. PB-CuO-V5-CASC3 siRes 110-480 188/218-mut

   Plasmid

   #158544

   Purpose

   For PiggyBac-mediated integration of V5-tagged siRNA-resistant EJC-binding deficient CASC3 110-480

   Depositor

   Niels Gehring

   Article

   Gerbracht et al Nucleic Acids Res. 2020 Jul 4. pii: 5867

   Insert

   CASC3; BTZ; MLN51 (CASC3 Human)
   

   Tags

   V5

   Expression

   Mammalian

   Mutation

   Amino acids 110-480, C-terminal deletion, F188D, …

   Promoter

   CMV

   Available Since

   Oct. 21, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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8. pX330-Flag-SpCas9-HF1 (without sgRNA; with silent mutations)

   Plasmid

   #126755

   Purpose

   Expression plasmid for human codon-optimized increased fidelity SpCas9-HF1 (without U6-sgRNA coding sequence, with silent mutations)

   Depositor

   Ervin Welker

   Article

   Kulcsar et al Nat Commun. 2020 Mar 6;11(1):1223. doi:

   Insert

   SpCas9-HF1
   

   Use

   CRISPR

   Tags

   3xFLAG and NLS

   Expression

   Mammalian

   Mutation

   N497A, R661A, Q695A, Q926A

   Promoter

   CBh

   Available Since

   March 6, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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9. pTYB3-human PUM1-HD MUT7-2 (S1079N-E1083Q)-intein-CBD

   Plasmid

   #73299

   Purpose

   Expresses mutant human PUM1-HD

   Depositor

   Traci Hall

   Article

   Cheong et al Proc Natl Acad Sci U S A. 2006 Sep 12;10

   Insert

   human PUM1 Pumilio homology domain (PUM1 Human)
   

   Tags

   intein

   Expression

   Bacterial

   Mutation

   S1079N-E1083Q

   Available Since

   Feb. 24, 2016

   Availability

   Academic Institutions and Nonprofits only

10. pMIR-Report-RASA1-3'UTR (mut - miR-206 site)

    Plasmid

    #62576

    Purpose

    Translational Luciferase Reporter containing the mutated 3'UTR of RASA1. The miR-206 binding site was mutated.

    Depositor

    Michael Ruppert

    Article

    Sharma et al Mol Cell Biol. 2014 Nov 15;34(22):4143-6

    Insert

    RASA1 (RASA1 Human)
    

    Use

    Luciferase

    Tags

    None

    Mutation

    miR-206 binding site mutated (ACATTCCA --> AAC…

    Available Since

    May 28, 2015

    Availability

    Academic Institutions and Nonprofits only

11. siRNA-resistant SigmaR1-mNeonGreen a4mut (I178A L182A L186A V190A)

    Plasmid

    #226577

    Purpose

    Encodes mutant siRNA resistant SigmaR1 protein (substitutions) labeled with mNeonGreen

    Depositor

    Gia Voeltz

    Article

    Sawyer et al Dev Cell. 2024 Jul 2:S1534-5807(24)00382

    Insert

    SigmaR1 (Sigma-1 Receptor) (SIGMAR1 Human)
    

    Tags

    mNeonGreen

    Expression

    Mammalian

    Mutation

    I178A, L182A, L186A, V190A

    Available Since

    Nov. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pLY57_TRAC-LHA-pAAV-EFS-CD22BBz-PRODH2-TRAC-RHA(3166mut)

    Plasmid

    #192188

    Purpose

    CD22 CAR AAV vector PRODH2 KI (pLY057)

    Depositor

    Sidi Chen

    Article

    Ye et al Cell Metab. 2022 Apr 5;34(4):595-614.e14

    Insert

    CD22 CAR AAV vector PRODH2 KI (pLY057) (CD22 Synthetic)
    

    Use

    AAV; Mammalian expression

    Mutation

    NA

    Available Since

    Oct. 24, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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13. L4791 VEGFR2 NTEVp chain (75S NTEVp mutant) in PolyTX-mNeonGreen

    Plasmid

    #244172

    Purpose

    Constitutive expression of a MESA NTEVp chain encoding (N to C): VEGFR2SS-3xFLAG-VEGFR2ECD-VEGFR2TMD-NTEVp(75S)

    Depositor

    Joshua Leonard

    Article

    Edelstein et al Nat Chem Biol. 2025 Aug 22:10.1038/s4158

    Insert

    MESA NTEVp chain with human VEGFR2 SS, ECD and TMD, and NTEVp (75S) (KDR Human, Synthetic)
    

    Use

    Synthetic Biology

    Tags

    VEGFR2 signal peptide - 3xFLAG

    Expression

    Mammalian

    Mutation

    NTEVp_75S

    Promoter

    hEF1a

    Available Since

    Oct. 2, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. Mirror GFP[ENE(C8351G)-mascRNA(mut 8356-8370)](pAVA3871)

    Plasmid

    #239352

    Purpose

    Expresses TEV protease and tandemly-repeated GFP fluorescent proteins to amplify the fluorescence signal produced by a single transcription unit of MALAT1 ENE(C8351G)-mascRNA(mut 8356-8370) reporter.

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    MALAT1 ENE(C8351G)-mascRNA(mut 8356-8370)
    

    Expression

    Mammalian

    Mutation

    MALAT1 ENE(C8351G)-mascRNA(mut 8356-8370: ctacgac…

    Available Since

    Aug. 26, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pAAV-rev(CMV-TagBFP2)-EFS-mCherry-124-MUT-MRE

    Plasmid

    #235148

    Purpose

    Expresses the mCherry-based mutated (control) sensor for miR-124. TagBFP2 is expressed as a transduction reporter

    Depositor

    Giordano Lippi

    Article

    Zolboot et al Neuron. 2025 Apr 1:S0896-6273(25)00181-3

    Insert

    mCherry with a mutated miR-124 MRE
    

    Use

    AAV

    Mutation

    7 nucleotides of the miR-124 WT MRE mutated

    Promoter

    EFS

    Available Since

    April 23, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. pAc5.1-PH-mCherry-Oskar 139-240 MUT (A162E/L228E) (HK202)

    Plasmid

    #206464

    Purpose

    Oskar 139-240 mut expression in Schneider cells for imaging

    Depositor

    Mandy Jeske

    Article

    Salgania et al Nat Commun. 2024 Apr 3;15(1):2875. doi:

    Insert

    Oskar 139-240 mut (osk Fly)
    

    Tags

    PH mcherry

    Expression

    Insect

    Mutation

    A162E L228E)

    Available Since

    July 24, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. pAc5.1B-EGFP-CeAIN2_254-400-DmGW182_635-1384-CIM1-P-GLmut-F961A_S

    Plasmid

    #147515

    Purpose

    Insect Expression of CeAIN2_254-400-DmGW182_635-1384-CIM1-P-GLmut-F961A

    Depositor

    Elisa Izaurralde

    Article

    Huntzinger et al Nucleic Acids Res. 2013 Jan;41(2):978-94

    Insert

    CeAIN2_254-400-DmGW182_635-1384-CIM1-P-GLmut-F961A (gw Human, Nematode)
    

    Expression

    Insect

    Mutation

    Deletion of 2 AA (SD) at position 378-379 compare…

    Available Since

    March 16, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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18. pAc5.1B-EGFP-CeAIN2_254-400-DmGW182_635-1384-M2WA-CIM1mut-F961A_R

    Plasmid

    #147389

    Purpose

    Insect Expression of CeAIN2_254-400-DmGW182_635-1384-M2WA-CIM1mut-F961A

    Depositor

    Elisa Izaurralde

    Article

    Huntzinger et al Nucleic Acids Res. 2013 Jan;41(2):978-94

    Insert

    CeAIN2_254-400-DmGW182_635-1384-M2WA-CIM1mut-F961A (gw Nematode, Fly)
    

    Expression

    Insect

    Mutation

    Deletion of 2 AA (SD) at position 378-379 compare…

    Available Since

    March 16, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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19. pAc5.1B-EGFP-CeAIN2_254-400-HsTNRC6C_1207-1690-CIM1-2mut-F1389A_R

    Plasmid

    #147394

    Purpose

    Insect Expression of CeAIN2_254-400-HsTNRC6C_1207-1690-CIM1-2mut-F1389A

    Depositor

    Elisa Izaurralde

    Article

    Huntzinger et al Nucleic Acids Res. 2013 Jan;41(2):978-94

    Insert

    CeAIN2_254-400-HsTNRC6C_1207-1690-CIM1-2mut-F1389A (TNRC6C Human, Nematode)
    

    Expression

    Insect

    Mutation

    Deletion of 2 AA (SD) at position 378-379 compare…

    Available Since

    May 6, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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20. pLV-Hygro-EF1a-XRCC1-EGFP-T2A-Myc-POLB(PAMmut)

    Plasmid

    #176139

    Purpose

    EGFP fused to the C-terminus of XRCC1, linked by T2A to N-terminus Myc-tagged POLB with a mutation in the PAM site used by POLBKO gRNA1 & a hygromycin resistance cassette

    Depositor

    Robert Sobol

    Article

    Koczor et al Cell Rep. 2021 Nov 2;37(5):109917. doi:

    Insert

    XRCC1-T2A-PolB (XRCC1, POLB Human)
    

    Use

    Lentiviral

    Tags

    EGFP and MYC

    Expression

    Mammalian

    Promoter

    EF1A

    Available Since

    Jan. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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