We narrowed to 256 results for: Map2

1. pEBG MKK3b(Glu, delete LXL)

   Plasmid

   #50452

   Purpose

   activates p38 in the signaling pathway

   Depositor

   Roger Davis

   Article

   Enslen et al EMBO J. 2000 Mar 15. 19(6):1301-11.

   Insert

   MKK3b (MAP2K3 Human)
   

   Use

   Tags

   Gst

   Expression

   Mammalian

   Mutation

   deleted L25-I27, changed Serine 218 to Glutamic A…

   Promoter

   SV40

   Available since

   Jan. 22, 2014

   Availability

   Academic Institutions and Nonprofits only

2. pGEX-4T-1 3xHA-MKK4-EE

   Plasmid

   #47577

   Purpose

   Bacterial expression plasmid for GST-3xHA-tagged constitutively active MKK4

   Depositor

   Kevin Janes

   Article

   Bose et al Mol Cell Proteomics. 2013 Mar;12(3):797-

   Insert

   MKK4-EE (MAP2K4 Human)
   

   Use

   Tags

   3xHA and GST

   Expression

   Bacterial

   Mutation

   Lacks the first 36 residues of the RefSeq protein…

   Promoter

   Available since

   Aug. 28, 2013

   Availability

   Academic Institutions and Nonprofits only

3. pWZLblasti-HA-MEK1 C121S

   Plasmid

   #53165

   Purpose

   Expresses HA tagged human MEK1 C121S from blasticidin resistance retroviral vector

   Depositor

   Christopher Counter

   Article

   Brady et al Nature. 2014 Apr 9. doi: 10.1038/nature1

   Insert

   MEK1 (MAP2K1 Human)
   

   Use

   Retroviral

   Tags

   HA

   Expression

   Mammalian

   Mutation

   C121S

   Promoter

   Available since

   June 24, 2014

   Availability

   Academic Institutions and Nonprofits only

4. pGEX6P1-HA-MEK1 C121S

   Plasmid

   #53164

   Purpose

   Expresses GST-HA tagged human MEK1 C121S from bacterial expression vector

   Depositor

   Christopher Counter

   Article

   Brady et al Nature. 2014 Apr 9. doi: 10.1038/nature1

   Insert

   MEK1 (MAP2K1 Human)
   

   Use

   Tags

   GST and HA

   Expression

   Bacterial

   Mutation

   C121S

   Promoter

   Available since

   June 9, 2014

   Availability

   Academic Institutions and Nonprofits only

5. pSUPER-retro-puro-tetO-Mek1-shRNA

   Plasmid

   #53179

   Purpose

   Expresses shRNA against mouse Mek1 from puromycin resistance retroviral vector

   Depositor

   Christopher Counter

   Article

   Brady et al Nature. 2014 Apr 9. doi: 10.1038/nature1

   Insert

   MEK1 (Map2k1 Mouse)
   

   Use

   RNAi and Retroviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   June 19, 2014

   Availability

   Academic Institutions and Nonprofits only

6. pGEX6P1-HA-MEK1 CBM

   Plasmid

   #53163

   Purpose

   Expresses GST-HA tagged human MEK1 M187AH188AM230AH239A from bacterial expression vector

   Depositor

   Christopher Counter

   Article

   Brady et al Nature. 2014 Apr 9. doi: 10.1038/nature1

   Insert

   MEK1 (MAP2K1 Human)
   

   Use

   Tags

   GST and HA

   Expression

   Bacterial

   Mutation

   M187A/H188A/M230A/H239A

   Promoter

   Available since

   June 9, 2014

   Availability

   Academic Institutions and Nonprofits only

7. LV_EF1a_MEK1(S218D,S222D)-P2A-Hygro_Barcode

   Plasmid

   #170240

   Purpose

   Barcoded lentiviral vector to express MEK1 (S218D, S222D) in mammalian cells under control of EF1a promoter. Barcoded for transcript detection in single cell RNA-seq

   Depositor

   Prashant Mali

   Article

   Parekh et al iScience. 2021 Sep 20;24(10):103149. doi

   Insert

   MAP2K1 (MAP2K1 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   S218D, S222D

   Promoter

   EF1a

   Available since

   Sept. 23, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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8. pEN_TT MEK5-DD-mRFP1

   Plasmid

   #47547

   Purpose

   Gateway entry vector for an inducible mRFP1-tagged constitutively active MEK5 mutant

   Depositor

   Kevin Janes

   Article

   Jensen et al Cell Host Microbe. 2013 Jan 16;13(1):67-

   Insert

   MEK5-DD (MAP2K5 Human)
   

   Use

   Entry vector

   Tags

   mRFP

   Expression

   Mutation

   S311D, T315D

   Promoter

   Available since

   Sept. 6, 2013

   Availability

   Academic Institutions and Nonprofits only

9. pSLIK MEK5-DD-mRFP1 neo

   Plasmid

   #47548

   Purpose

   Lentiviral expression vector for an inducible mRFP1-tagged constitutively active MEK5 mutant

   Depositor

   Kevin Janes

   Article

   Jensen et al Cell Host Microbe. 2013 Jan 16;13(1):67-

   Insert

   MEK5-DD-mRFP1 (MAP2K5 Human)
   

   Use

   Lentiviral

   Tags

   mRFP

   Expression

   Mammalian

   Mutation

   S311D, T315D

   Promoter

   Available since

   Aug. 28, 2013

   Availability

   Academic Institutions and Nonprofits only

10. MEK1C222

    Plasmid

    #164638

    Purpose

    Bacterial expression plasmid for His6-MEK1C222

    Depositor

    Ben Davis

    Article

    Lai et al Cell. 2021 Apr 27. pii: S0092-8674(21)00

    Insert

    mitogen-activated protein kinase kinase 1 (MAP2K1 Human)
    

    Use

    Tags

    His6-tag

    Expression

    Bacterial

    Mutation

    G(-19)F/S222C/C277S/C376S

    Promoter

    T7

    Available since

    May 5, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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11. MEK1C218

    Plasmid

    #164639

    Purpose

    Bacterial expression plasmid for His6-MEK1C218

    Depositor

    Ben Davis

    Article

    Lai et al Cell. 2021 Apr 27. pii: S0092-8674(21)00

    Insert

    mitogen-activated protein kinase kinase 1 (MAP2K1 Human)
    

    Use

    Tags

    His6-tag

    Expression

    Bacterial

    Mutation

    G(-19)F/S218C/C277S/C376S

    Promoter

    T7

    Available since

    May 5, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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12. MEK1C218C222

    Plasmid

    #164640

    Purpose

    Bacterial expression plasmid for His6-MEK1C218C222

    Depositor

    Ben Davis

    Article

    Lai et al Cell. 2021 Apr 27. pii: S0092-8674(21)00

    Insert

    mitogen-activated protein kinase kinase 1 (MAP2K1 Human)
    

    Use

    Tags

    His6-tag

    Expression

    Bacterial

    Mutation

    G(-19)F/S218C/S222C/C277S/C376S

    Promoter

    T7

    Available since

    May 5, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. MEK1 (S218D,S222D)-pcw107

    Plasmid

    #64604

    Purpose

    when used to produce lentivirus, express physiological levels of insert

    Depositor

    David Sabatini, Kris Wood

    Article

    Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

    Insert

    MAP2K1 (MAP2K1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    S218D, S222D

    Promoter

    PGK

    Available since

    June 18, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pCDNA3 Flag MKK7B2Jnk3a2

    Plasmid

    #19729

    Depositor

    Roger Davis

    Article

    Lei et al Mol Cell Biol. 2002 Jul . 22(13):4929-42

    Insert

    MKK7B2Jnk3a2 (Map2k7, MAPK10 Mouse, Human)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    March 31, 2009

    Availability

    Academic Institutions and Nonprofits only

15. MEK5 DD(S311D,T315D)-pcw107-V5

    Plasmid

    #64619

    Purpose

    when used to produce lentivirus, express physiological levels of insert

    Depositor

    David Sabatini, Kris Wood

    Article

    Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

    Insert

    MAP2K5 (MAP2K5 Human)
    

    Use

    Lentiviral

    Tags

    V5

    Expression

    Mutation

    S311D, T315D*

    Promoter

    PGK

    Available since

    June 1, 2015

    Availability

    Academic Institutions and Nonprofits only

16. MEK1-pcw107-V5

    Plasmid

    #64650

    Purpose

    (control) when used to produce lentivirus, express physiological levels of insert

    Depositor

    David Sabatini, Kris Wood

    Article

    Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

    Insert

    MAP2K1 (MAP2K1 Human)
    

    Use

    Lentiviral

    Tags

    V5

    Expression

    Mutation

    Promoter

    PGK

    Available since

    Dec. 21, 2015

    Availability

    Academic Institutions and Nonprofits only

17. FLAG-MKK6 (S207E,T211E)-pcw107

    Plasmid

    #64625

    Purpose

    when used to produce lentivirus, express physiological levels of insert

    Depositor

    David Sabatini, Kris Wood

    Article

    Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

    Insert

    MAP2K6 (MAP2K6 Human)
    

    Use

    Lentiviral

    Tags

    FLAG

    Expression

    Mutation

    S207E,T211E

    Promoter

    PGK

    Available since

    June 10, 2015

    Availability

    Academic Institutions and Nonprofits only

18. myr-FLAG-MEK5-pcw107

    Plasmid

    #64620

    Purpose

    when used to produce lentivirus, express physiological levels of insert

    Depositor

    David Sabatini, Kris Wood

    Article

    Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

    Insert

    MAP2K5 (MAP2K5 Human)
    

    Use

    Lentiviral

    Tags

    Flag and myristoylated

    Expression

    Mutation

    Promoter

    PGK

    Available since

    Nov. 30, 2015

    Availability

    Academic Institutions and Nonprofits only

19. Δ1-60MEK1C222

    Plasmid

    #164641

    Purpose

    Bacterial expression plasmid for His6-ΔMEK1C222

    Depositor

    Ben Davis

    Article

    Lai et al Cell. 2021 Apr 27. pii: S0092-8674(21)00

    Insert

    N-terminal truncated mitogen-activated protein kinase kinase 1 (MAP2K1 Human)
    

    Use

    Tags

    His6-tag

    Expression

    Bacterial

    Mutation

    S222C/C277S/C376S; residues 1-60 at N-terminus we…

    Promoter

    T7

    Available since

    May 5, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. Δ1-60MEK1C218

    Plasmid

    #164643

    Purpose

    Bacterial expression plasmid for His6-ΔMEK1C218

    Depositor

    Ben Davis

    Article

    Lai et al Cell. 2021 Apr 27. pii: S0092-8674(21)00

    Insert

    N-terminal truncated mitogen-activated protein kinase kinase 1 (MAP2K1 Human)
    

    Use

    Tags

    His6-tag

    Expression

    Bacterial

    Mutation

    S218C/C277S/C376S; residues 1-60 at N-terminus we…

    Promoter

    T7

    Available since

    May 5, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge