59,455 results

1. IDG_KCND1_OE_1

   Plasmid

   #161640

   Purpose

   Overexpresses KCND1

   Depositor

   Mike McManus

   Insert

   KCND1 (KCND1 Human)
   

   Tags

   V5

   Expression

   Mammalian

   Available Since

   Sept. 6, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pESR1.1.0-gDNA

   Plasmid

   #112433

   Purpose

   CRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor ESR1

   Depositor

   Kevin White

   Insert

   ESR1 (ESR1 Human)
   

   Use

   CRISPR

   Expression

   Mammalian

   Available Since

   Dec. 7, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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3. mEmerald-Myopalladin-C-14

   Plasmid

   #54188

   Purpose

   Localization: Cytoskeleton , Excitation: 487, Emission: 509

   Depositor

   Michael Davidson

   Insert

   Myopalladin (MYPN Human)
   

   Tags

   mEmerald

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   July 25, 2014

   Availability

   Industry, Academic Institutions, and Nonprofits

4. mEos4a-Actin-C-18

   Plasmid

   #57488

   Purpose

   Localization: Actin, Excitation: 505 / 569, Emission: 516 / 581

   Depositor

   Loren Looger, Michael Davidson

   Insert

   Actin (ACTB Human)
   

   Tags

   mEos4a

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   March 12, 2015

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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5. pHAGE-XPO1-R749Q

   Plasmid

   #116709

   Purpose

   Lentiviral expression of XPO1 R749Q

   Depositor

   Gordon Mills, Kenneth Scott

   Article

   Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

   Insert

   XPO1 (XPO1 Human)
   

   Use

   Lentiviral

   Mutation

   R749Q

   Available Since

   March 14, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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6. CDK2 gRNA (BRDN0001148950)

   Plasmid

   #77193

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CDK2

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   CDK2 (CDK2 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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7. pDONR221-SLC38A5_STOP

   Plasmid

   #161284

   Purpose

   Gateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors. Contains a STOP codon at the end of the codon-optimized ORF sequence.

   Depositor

   Giulio Superti-Furga, RESOLUTE Consortium

   Article

   Superti-Furga et al Nat Rev Drug Discov. 2020 Jul;19(7):429-

   Insert

   SLC38A5 (SLC38A5 Human)
   

   Expression

   Mammalian

   Available Since

   Sept. 15, 2021

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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8. pD649-HAsp-ROBO3-Fc(DAPA)-AviTag-6xHis

   Plasmid

   #156997

   Purpose

   Mammalian expression of cell-surface protein extracellular domain fused to Fc(DAPA)-Avi-6xHis. Protein is secreted from cells.

   Depositor

   Chris Garcia

   Article

   Wojtowicz et al Cell. 2020 Aug 20;182(4):1027-1043.e17.

   Insert

   ROBO3 (ROBO3 Human)
   

   Tags

   Fc(DAPA)-AviTag-6xHis

   Expression

   Mammalian

   Mutation

   Fc region of human IgG contains D265A and P329A m…

   Promoter

   CMV/SP6

   Available Since

   March 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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9. mTurquoise-ZO1-C-14

   Plasmid

   #55588

   Purpose

   Localization: Tight Junctions, Excitation: 434, Emission: 474

   Depositor

   Michael Davidson

   Insert

   ZO1 (TJP1 Human)
   

   Tags

   mTurquoise

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Oct. 10, 2014

   Availability

   Industry, Academic Institutions, and Nonprofits

10. pShuttle-EGFP-CLASP2 340-1362 9xS/A

    Plasmid

    #24373

    Depositor

    Torsten Wittmann

    Article

    Kumar et al J Cell Biol. 2009 Mar 23. 184(6):895-908

    Insert

    CLASP2 (340-1362) 9xS/A (CLASP2 Human)
    

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    Nonphosphorylatable CLASP2 deletion mutant. M…

    Available Since

    June 29, 2010

    Availability

    Academic Institutions and Nonprofits only

    

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11. pDONR223_MAP2K1_WT

    Plasmid

    #81920

    Purpose

    Gateway Donor vector containing MAP2K1 , part of the Target Accelerator Plasmid Collection.

    Depositor

    David Root, Jesse Boehm, William Hahn

    Article

    Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

    Insert

    MAP2K1 (MAP2K1 Human)
    

    Use

    Gateway entry vector

    Mutation

    I310N

    Promoter

    None

    Available Since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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12. pLenti6-DEST PINK1-V5 WT

    Plasmid

    #13320

    Depositor

    Mark Cookson

    Article

    Beilina et al Proc Natl Acad Sci U S A. 2005 Apr 19. 1

    Insert

    PINK1 (PINK1 Human)
    

    Use

    Lentiviral

    Tags

    V5

    Expression

    Mammalian

    Available Since

    Oct. 16, 2006

    Availability

    Academic Institutions and Nonprofits only

    

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13. pDONR223_MAP2K1_p.P124S

    Plasmid

    #81703

    Purpose

    Gateway Donor vector containing MAP2K1, part of the Target Accelerator Plasmid Collection.

    Depositor

    David Root, Jesse Boehm, William Hahn

    Article

    Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

    Insert

    MAP2K1 (MAP2K1 Human)
    

    Use

    Gateway entry vector

    Mutation

    P124S; I310N

    Promoter

    None

    Available Since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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14. CRY2olig-PR

    Plasmid

    #218917

    Purpose

    Expression of CRY2olig-mCherry fused to a codon-optimised poly-PR sequence

    Depositor

    Tatyana Shelkovnikova

    Article

    Hodgson et al iScience. 2024 Sep 14;27(10):110937. doi

    Insert

    CRY2olig-mCherry tagged poly-PR
    

    Expression

    Mammalian

    Mutation

    wild-type

    Promoter

    CMV

    Available Since

    Aug. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. CRY2olig-GR

    Plasmid

    #218919

    Purpose

    Expression of CRY2olig-mCherry fused to a codon-optimised poly-GR sequence

    Depositor

    Tatyana Shelkovnikova

    Article

    Hodgson et al iScience. 2024 Sep 14;27(10):110937. doi

    Insert

    CRY2olig-mCherry tagged poly-GR
    

    Expression

    Mammalian

    Mutation

    wild-type

    Promoter

    CMV

    Available Since

    Aug. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. mCherry VPS37b

    Plasmid

    #245030

    Purpose

    Protein localization of human wild-type VPS37b in cells

    Depositor

    Thomas Martin

    Insert

    VPS37b (VPS37B Human)
    

    Tags

    mCherry

    Expression

    Bacterial

    Available Since

    Sept. 30, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pME-V5-mClover-KRAS4A-G12D (JDW 813)

    Plasmid

    #242567

    Purpose

    Gateway middle entry clone containing an mClover3 fused human KRAS4A G12D.

    Depositor

    Joshua Wythe

    Article

    Gillespie et al bioRxiv [Preprint]. 2024 Jul 13:2024.07.

    Insert

    KRAS4A-G12D (KRAS Human)
    

    Use

    Gateway subcloning

    Available Since

    Sept. 11, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. pCA528 IST1 (1-366)

    Plasmid

    #193039

    Purpose

    Bacterial expression plasmid for full-length IST1 (1-366).

    Depositor

    Wesley Sundquist

    Article

    Paine et al Elife. 2023 Sep 29;12:e84515. doi: 10.75

    Insert

    IST1 (IST1 Human)
    

    Tags

    6xHis-Sumo

    Expression

    Bacterial

    Promoter

    T7

    Available Since

    Dec. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. DRH031_ AAV-SIO-nEF-WT-THR

    Plasmid

    #225090

    Purpose

    Cre-dependent expression of wild-type thyroid receptor beta (THRB, human) in neurons driven by nEF promoter.

    Depositor

    Bernardo Sabatini

    Article

    Hochbaum et al Cell. 2024 Oct 3;187(20):5679-5697.e23.

    Insert

    DN-THRB (THRB Human)
    

    Use

    AAV

    Available Since

    Oct. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. DRH032_ AAV-SIO-nEF-DN-THR

    Plasmid

    #225091

    Purpose

    Cre-dependent expression of dominant-negative thyroid receptor beta (THRB, human) in neurons driven by nEF promoter.

    Depositor

    Bernardo Sabatini

    Article

    Hochbaum et al Cell. 2024 Oct 3;187(20):5679-5697.e23.

    Insert

    WT-THRB (THRB Human)
    

    Use

    AAV

    Available Since

    Oct. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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