We narrowed to 4,269 results for: Bre;

1. myc-hRAD18 d6BD

   Plasmid

   #68832

   Purpose

   Expresses c-myc-tagged human RAD18 deleting hRAD6 binding domain

   Depositor

   Satoshi Tateishi

   Article

   Watanabe et al Nucleic Acids Res. 2009 Apr;37(7):2176-9

   Insert

   c-myc tagged human RAD18 deleting hRAD6 binding domain (RAD18 Human)
   

   Use

   Tags

   c-myc

   Expression

   Mammalian

   Mutation

   Promoter

   CAG

   Available since

   Oct. 1, 2015

   Availability

   Academic Institutions and Nonprofits only

2. HA-BAP1-N102S-GFP

   Plasmid

   #78915

   Purpose

   Mammalian expression of BAP1 with N102S and an EGFP fusion

   Depositor

   Michael Hendzel

   Article

   Ismail et al Cancer Res. 2014 Aug 15;74(16):4282-94.

   Insert

   BAP1 (BAP1 Human)
   

   Use

   Tags

   EGFP and HA

   Expression

   Mammalian

   Mutation

   N102S

   Promoter

   CMV

   Available since

   July 20, 2016

   Availability

   Academic Institutions and Nonprofits only

3. p3xFLAG-CMV-RNF8-N-terminus(1-140)

   Plasmid

   #64675

   Purpose

   expresses only N terminus of RNF8, amino acids 1 to 140

   Depositor

   Marianne Farnebo

   Article

   Henriksson et al Genes Dev. 2014 Dec 15;28(24):2726-38. d

   Insert

   Ring finger protein 8 (RNF8 Human)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   only N terminus amino acids 1-140

   Promoter

   CMV

   Available since

   May 20, 2015

   Availability

   Academic Institutions and Nonprofits only

4. sgRNA BRCA2 V2102I

   Plasmid

   #139322

   Purpose

   Plasmid expressing a sgRNA to introduce BRCA2 V2102I using base editing

   Depositor

   Alberto Ciccia

   Article

   Billon et al Cell Rep. 2020 Mar 10;30(10):3280-3295.e

   Insert

   sgRNA to insert BRCA2 V2102I using base editing
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   May 22, 2020

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. sgRNA BRCA2 E2772K

   Plasmid

   #139323

   Purpose

   Plasmid expressing a sgRNA to introduce BRCA2 E2772K using base editing

   Depositor

   Alberto Ciccia

   Article

   Billon et al Cell Rep. 2020 Mar 10;30(10):3280-3295.e

   Insert

   sgRNA to insert BRCA2 E2772K using base editing
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   May 22, 2020

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pLV-CMV-EGFP-PolB-Hygro

   Plasmid

   #176056

   Purpose

   EGFP fused to the N-terminus of PolB & a hygromycin resistance cassette

   Depositor

   Robert Sobol

   Article

   Koczor et al Cell Rep. 2021 Nov 2;37(5):109917. doi:

   Insert

   PolB (POLB Human)
   

   Use

   Lentiviral

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   Jan. 24, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. FLAG-EglN2 wt-pBabe-Puro

   Plasmid

   #22704

   Depositor

   William Kaelin

   Article

   Zhang et al Cancer Cell. 2009 Nov 6. 16(5):413-24.

   Insert

   Egg laying Nine - 2 (EglN2) (EGLN2 Human)
   

   Use

   Retroviral

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   wt cDNA

   Promoter

   Available since

   Dec. 3, 2009

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pQC hKGA.wt V5-His IRES G418

   Plasmid

   #110390

   Purpose

   γ-Retroviral transfer vector for expressing glutminase isoform KGA (wild type), C-terminal V5-6xHis tags, IRES-driven Geneticin selection.

   Depositor

   Sandra Martha Gomes Dias

   Insert

   KGA glutaminase (GLS Human)
   

   Use

   Retroviral

   Tags

   6xHis and V5

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   Feb. 23, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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9. pX330 L-FKBP-Cas9

   Plasmid

   #162728

   Purpose

   Mammalian expression

   Depositor

   Amit Choudhary

   Article

   Sreekanth et al ACS Cent Sci. 2020 Dec 23;6(12):2228-223

   Insert

   FKBP F36V
   

   Use

   CRISPR

   Tags

   3xFLAG

   Expression

   Mammalian

   Mutation

   Promoter

   CBh

   Available since

   Jan. 12, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pEGFP-WRAP53beta-DC-mutant-G435R

    Plasmid

    #64684

    Purpose

    expresses single mutated WRAP53beta at G435R, found in Dyskeratosis congenita patients

    Depositor

    Marianne Farnebo

    Article

    Henriksson et al Genes Dev. 2014 Dec 15;28(24):2726-38. d

    Insert

    WD40-encoding RNA antisense to P53 (WRAP53 Human)
    

    Use

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    mutation at G435R

    Promoter

    CMV

    Available since

    May 21, 2015

    Availability

    Academic Institutions and Nonprofits only

11. pEGFP-WRAP53beta-DC-mutant-R398W

    Plasmid

    #64683

    Purpose

    expresses single mutated WRAP53beta at R398W, found in Dyskeratosis congenita patients

    Depositor

    Marianne Farnebo

    Article

    Henriksson et al Genes Dev. 2014 Dec 15;28(24):2726-38. d

    Insert

    WD40-encoding RNA antisense to P53 (WRAP53 Human)
    

    Use

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    mutation at R398W

    Promoter

    CMV

    Available since

    May 21, 2015

    Availability

    Academic Institutions and Nonprofits only

12. GFP SDPR

    Plasmid

    #68398

    Purpose

    Expression of fluorescently tagged SDPR in mammalian cells

    Depositor

    Rob Parton

    Article

    Bastiani et al J Cell Biol. 2009 Jun 29;185(7):1259-73.

    Insert

    SDPR (Sdpr Mouse)
    

    Use

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Sept. 24, 2015

    Availability

    Academic Institutions and Nonprofits only

13. TET-pLKO.1 PURO shId2 #2

    Plasmid

    #83090

    Purpose

    Lentiviral shRNA vector for inducible knockdown of mouse Id2

    Depositor

    Kevin Janes

    Article

    Bajikar et al Dev Cell. 2017 Nov 20;43(4):418-435.e13.

    Insert

    shId2 (Id2 Mouse)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Feb. 28, 2019

    Availability

    Academic Institutions and Nonprofits only

14. pLKO.1P CISD2_2

    Plasmid

    #160776

    Purpose

    Suppress CISD2

    Depositor

    Richard Possemato

    Article

    Sviderskiy et al Mol Cell. 2020 Oct 28. pii: S1097-2765(2

    Insert

    shCISD2_2
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Oct. 29, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pLKO.1P CISD2_1

    Plasmid

    #160775

    Purpose

    Suppress CISD2

    Depositor

    Richard Possemato

    Article

    Sviderskiy et al Mol Cell. 2020 Oct 28. pii: S1097-2765(2

    Insert

    shCISD2_1
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Oct. 29, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pcDNA3.1(+)/Puro/FA/GFP-N--Grb2-4

    Plasmid

    #112839

    Purpose

    transient/stable overexpression

    Depositor

    Tomasz Prószyński

    Article

    Gingras et al J Cell Sci. 2016 Mar 1;129(5):898-911. d

    Insert

    Grb2 (Grb2 Mouse)
    

    Use

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    SH3 (N-term) domain of Grb2

    Promoter

    Available since

    Aug. 8, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pEGFP-WRAP53beta-DC-mutant-F164L

    Plasmid

    #64681

    Purpose

    expresses single mutated WRAP53beta at F164L, found in Dyskeratosis congenita patients

    Depositor

    Marianne Farnebo

    Article

    Henriksson et al Genes Dev. 2014 Dec 15;28(24):2726-38. d

    Insert

    WD40-encoding RNA antisense to P53 (WRAP53 Human)
    

    Use

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    mutation at F164L

    Promoter

    CMV

    Available since

    May 21, 2015

    Availability

    Academic Institutions and Nonprofits only

18. pEGFP-WRAP53beta-DC-mutant-H376Y

    Plasmid

    #64682

    Purpose

    expresses single mutated WRAP53beta at H376Y, found in Dyskeratosis congenita patients

    Depositor

    Marianne Farnebo

    Article

    Henriksson et al Genes Dev. 2014 Dec 15;28(24):2726-38. d

    Insert

    WD40-encoding RNA antisense to P53 (WRAP53 Human)
    

    Use

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    mutation at H376Y

    Promoter

    CMV

    Available since

    May 21, 2015

    Availability

    Academic Institutions and Nonprofits only

19. pGL2 p15 4xSBR2 Mut 3' box

    Plasmid

    #15708

    Depositor

    Joan Massague

    Article

    Gomis et al Cancer Cell. 2006 Sep . 10(3):203-14.

    Insert

    p15 4xSBR2 (CDKN2B Human)
    

    Use

    Luciferase

    Tags

    Expression

    Mammalian

    Mutation

    Mutant 3' box. The 3' box contains the …

    Promoter

    Available since

    Sept. 7, 2007

    Availability

    Academic Institutions and Nonprofits only

20. pEN_TGmiR_Gb2-K

    Plasmid

    #25766

    Purpose

    Entry vector withTRE promoter driving mouse G beta 2 miR30-based shRNA with GFP coexpression.

    Depositor

    Iain Fraser

    Article

    Shin et al Proc Natl Acad Sci U S A. 2006 Sep 12. 1

    Insert

    Gb2 miR-shRNA (Gnb2 Mouse)
    

    Use

    Entry vector

    Tags

    GFP

    Expression

    Mutation

    Promoter

    Available since

    July 1, 2010

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. sgp27#1

    Plasmid

    #102759

    Purpose

    Expresses sgRNA targeting mouse p27

    Depositor

    Jin Chen

    Article

    Song et al Oncogene. 2017 Jun 5. doi: 10.1038/onc.2

    Insert

    p27 (Cdkn1b Mouse)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Nov. 1, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. sgRNA BRCA2 R2842C

    Plasmid

    #139324

    Purpose

    Plasmid expressing a sgRNA to introduce BRCA2 R2842C using base editing

    Depositor

    Alberto Ciccia

    Article

    Billon et al Cell Rep. 2020 Mar 10;30(10):3280-3295.e

    Insert

    sgRNA to insert BRCA2 R2842C using base editing
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    May 22, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. pLKO.1P MUTYH_2

    Plasmid

    #160786

    Purpose

    Suppress MUTYH

    Depositor

    Richard Possemato

    Article

    Sviderskiy et al Mol Cell. 2020 Oct 28. pii: S1097-2765(2

    Insert

    shMUTYH_2
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Oct. 29, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. pLKO.1P MUTYH_1

    Plasmid

    #160785

    Purpose

    Suppress MUTYH

    Depositor

    Richard Possemato

    Article

    Sviderskiy et al Mol Cell. 2020 Oct 28. pii: S1097-2765(2

    Insert

    shMUTYH_1
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Oct. 29, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. CNC3G (CASANOVA-C3 with glycine linkers)

    Plasmid

    #137192

    Purpose

    Expresses CNC3G (CASANOVA-C3 with glycine linkers), a blue light dependent NmeCas9 inhibitory protein

    Depositor

    Dominik Niopek

    Article

    Hoffmann et al Nucleic Acids Res. 2021 Mar 18;49(5):e29

    Insert

    CNC3G (CASANOVA-C3 with glycine linkers)
    

    Use

    CRISPR and Synthetic Biology

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Feb. 19, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. TET-pLKO.1 PURO shId2 #1

    Plasmid

    #83088

    Purpose

    Lentiviral shRNA vector for inducible knockdown of mouse Id2

    Depositor

    Kevin Janes

    Article

    Bajikar et al Dev Cell. 2017 Nov 20;43(4):418-435.e13.

    Insert

    shId2 (Id2 Mouse)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Feb. 28, 2019

    Availability

    Academic Institutions and Nonprofits only

27. pSLIK-Venus-TmiR-G13-G12

    Plasmid

    #25742

    Purpose

    Lentiviral vector with Tet-based inducible expression of both mouse G alpha 12 and G alpha 13 miR30-based shRNAs, constitutive Venus fluorescent protein coexpression.

    Depositor

    Iain Fraser

    Article

    Shin et al Proc Natl Acad Sci U S A. 2006 Sep 12. 1

    Insert

    G alpha 13 and 12 miR-shRNA
    

    Use

    Lentiviral and RNAi

    Tags

    Venus

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    July 14, 2010

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. p3xFLAG-CMV-RNF8-N-terminus(1-111)

    Plasmid

    #64674

    Purpose

    Expresses only N terminus of RNF8, amino acids 1 to 111

    Depositor

    Marianne Farnebo

    Article

    Henriksson et al Genes Dev. 2014 Dec 15;28(24):2726-38. d

    Insert

    Ring finger protein 8 (RNF8 Human)
    

    Use

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    Only N terminus amino acids 1-111

    Promoter

    CMV

    Available since

    May 19, 2015

    Availability

    Academic Institutions and Nonprofits only

29. RF-118-UB-BRCA1

    Plasmid

    #78960

    Purpose

    Expression of the C-terminal fragment of BRCA1 that is endogenously generated by caspase cleavage in mammalian cells

    Depositor

    Richard Fahlman

    Article

    Xu et al J Biol Chem. 2012 Mar 2;287(10):7495-502

    Insert

    BRCA1 (BRCA1 Human)
    

    Use

    Tags

    3x Flag and ubiquitin

    Expression

    Mammalian

    Mutation

    delta 1-1155

    Promoter

    CMV

    Available since

    March 8, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. 373_ESR1 in pmiRGlo

    Plasmid

    #78134

    Purpose

    luciferase reporter for miRNA activity

    Depositor

    Heidi Schwarzenbach

    Article

    Eichelser et al Oncotarget. 2014 Oct 30;5(20):9650-63.

    Insert

    ESR1 (ESR1 Human)
    

    Use

    Luciferase

    Tags

    luciferase

    Expression

    Mammalian

    Mutation

    3'UTR containing miRNA binding sites

    Promoter

    PGK

    Available since

    May 16, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge