We narrowed to 18,548 results for: MUT
-
Plasmid#60490PurposeContains a mutant version of the WT pSynSRE-T-Luc reporter plasmid. Four point mutations in the promoter SRE elements abolish SREBP-induced luciferase expression as described by Smith et al., 1988DepositorInsertHMG-CoA synthase promoter (-324/-225) fused to HMG-CoA synthase TATAA (-28/+39) transcription initiator sequence
UseLuciferaseTagsLuciferase reporterExpressionMammalianMutationFour point mutations (G->C or A->C) in the …PromoterPartial HMG-CoA synthase promoter (-324/-225) fus…Available SinceFeb. 9, 2016AvailabilityAcademic Institutions and Nonprofits only -
FH-TET3-HxDmut-pEF
Plasmid#127896PurposeExpresses ten-eleven-translocation 3 (TET3) containing HxD mutation at H1077Y and D1079ADepositorAvailable SinceOct. 1, 2019AvailabilityAcademic Institutions and Nonprofits only -
pCAG-G-Flamp2-mut
Plasmid#192783Purposecontrol probe of G-Flamp2, insensitive to cAMPDepositorInsertG-Flamp2-mut
TagsHis tagExpressionMammalianPromoterCAGAvailable SinceDec. 13, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hsyn-GRAB_Ado1.0mut
Plasmid#153287PurposeExpress the adenosine-insensitive control sensor GRAB_Ado1.0mut in neuronsDepositorInsertAdenosine-insensitive sensor GRAB_Ado1.0mut (control sensor)
UseAAVPromoterhSynAvailable SinceJuly 7, 2020AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn-GRAB_eCBmut
Plasmid#164605PurposeExpress the endocannabinoid non-responsive sensor GRAB_eCBmut in neuronsDepositorInsertEndocannabinoid non-responsive sensor GRAB_eCBmut
UseAAVMutationS383T, F177APromoterhSynAvailable SinceFeb. 18, 2021AvailabilityAcademic Institutions and Nonprofits only -
p3xFLAG-p62 PB1mut
Plasmid#204577PurposeExpresses 3xFLAG-p62 PB1mut in mammalian cellsDepositorAvailable SinceAug. 14, 2023AvailabilityAcademic Institutions and Nonprofits only -
mCherry-p62-Silent_Mutation_WT
Plasmid#187986Purposehuman p62 with silent mutation for sip62 #5 (Thermo Scientific). Internal reference: SMC516DepositorInsertp62 (NUP62 Human)
TagsmCherryExpressionMammalianMutationsilent mutation for resistance to sip62 #5Available SinceOct. 14, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn-GRAB_NEmut
Plasmid#123310PurposeExpresses the genetically-encoded fluorescent norepinephrine(NE) control sensor GRAB_NEmut in neuronsDepositorHas ServiceAAV Retrograde and AAV9InsertGPCR activation based NE control sensor GRAB_NEmut
UseAAVPromoterhSynAvailable SinceApril 4, 2019AvailabilityAcademic Institutions and Nonprofits only -
pCMV-APOBEC1-YTHmut
Plasmid#131637PurposeExpresses APOBEC1 fused to a mutant YTH domain with diminished m6A bindingDepositorInsertAPOBEC1-YTHmut-HA (YTHDF2 Human, Rat)
TagsHAExpressionMammalianMutationYTH domain lacks AA 385-409 comprising the m6A-bi…PromoterCMVAvailable SinceOct. 23, 2019AvailabilityAcademic Institutions and Nonprofits only -
pLDLR-Luc mutSRE
Plasmid#14945DepositorInsertLDLR promoter mut SRE (LDLR Human)
UseLuciferaseTagsluciferaseExpressionMammalianMutationPoint mutation in the SRE-1 sequence of the LDL r…Available SinceMay 21, 2007AvailabilityAcademic Institutions and Nonprofits only -
TLCV2-APOBEC1-YTHmut
Plasmid#178950PurposeLentiviral vector for dox-inducible expression of APOBEC1-YTHmut in mammalian cellsDepositorInsertAPOBEC1-YTHmut-T2A-GFP
UseLentiviral and Synthetic Biology; InducibleTagsHAExpressionMammalianPromotertight TREAvailable SinceApril 8, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hsyn-GRAB_HA1mut
Plasmid#190475PurposeExpress the histamine-insensitive control sensor GRAB_HA1mut in neuronsDepositorInsertHistamine-insensitive sensor GRAB_HA1mut (control sensor)
UseAAVPromoterhSynAvailable SinceDec. 8, 2022AvailabilityAcademic Institutions and Nonprofits only -
pCAG-G-Flamp1-mut
Plasmid#188568Purposecontrol probe of G-Flamp1, insensitive to cAMPDepositorInsertG-Flamp1-mut
TagsHis tagExpressionMammalianPromoterCAGAvailable SinceNov. 9, 2022AvailabilityAcademic Institutions and Nonprofits only -
pDae029 (eMutaT7[TadA-8e])
Plasmid#187620PurposeExpresses eMutaT7[TadA-8e] for mutagenizing genes downstream from a T7 promoter in e.coliDepositorInsertTadA-8e-T7RNAP
ExpressionBacterialAvailable SinceAug. 2, 2022AvailabilityAcademic Institutions and Nonprofits only -
pDisplay-GRAB_g5-HT3.0mut
Plasmid#208712PurposeExpresses the green 5-HT sensor GRAB_g5-HT3.0mut in mammalian cellsDepositorInsertGreen fluorescent 5-HT sensor GRAB_g5-HT3.0mut
ExpressionMammalianPromoterCMVAvailable SinceOct. 13, 2023AvailabilityAcademic Institutions and Nonprofits only -
pWUR 1+2 tetO mut89
Plasmid#80102PurposeEncodes a set of wild-type Cas1+2 and a mutant set of Cas1+2DepositorExpressionBacterialMutationQ24H, P202Q, G241D, E276D, L297QAvailable SinceDec. 23, 2016AvailabilityAcademic Institutions and Nonprofits only -
pAAV_CAG_FLEX_PKIαmut-P2A-mRuby3_WPRE
Plasmid#196678PurposeAAV plasmid for mammalian Cre-dependent expression of PKIαmut-P2A-mRuby3 under a CAG promotor w/ WPRE enhancer. PKIαmut bears the R20G/R21G mutation that renders it non-functional.DepositorInsertPKIαmut-P2A-mRuby3
UseAAV and Cre/LoxExpressionMammalianAvailable SinceFeb. 21, 2023AvailabilityAcademic Institutions and Nonprofits only -
pIVT-R2Tg-RTmut
Plasmid#238106PurposeFor IVT of RT-mutant R2Tg editor, codon optimized for mammalian expression.DepositorInsertReverse transcriptase mutant R2Tg, mammalian codon optimized
UseFor ivtAvailable SinceJuly 3, 2025AvailabilityAcademic Institutions and Nonprofits only -
MSCV JMJD3 mutant
Plasmid#21214DepositorAvailable SinceJune 23, 2009AvailabilityAcademic Institutions and Nonprofits only -
pAAV-GfaABC1D-GRAB_ATP1.0mut
Plasmid#167580PurposeExpress the ATP-insensitive control sensor GRAB_ATP1.0mut in astrocytesDepositorInsertATP-insensitive sensor GRAB_ATP1.0mut (control sensor) (P2RY1 Human)
UseAAVPromoterGfaABC1DAvailable SinceMay 7, 2021AvailabilityAcademic Institutions and Nonprofits only -
pET-Sfp R4-4 mutant
Plasmid#173491PurposeExpression plasmid for mutant R4-4 of Sfp phosphopantetheinyl transferase. R4-4 can use 3′-dephospho CoA for adding the phosphopantetheinyl group to the carrier proteins.DepositorInsertSfp-R44
TagsHis tagExpressionBacterialAvailable SinceNov. 30, 2021AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hsyn-GRAB_ATP1.0mut
Plasmid#167578PurposeExpress the ATP-insensitive control sensor GRAB_ATP1.0mut in neuronsDepositorAvailable SinceApril 13, 2021AvailabilityAcademic Institutions and Nonprofits only -
pKEN GFP mut2
Plasmid#20409DepositorInsertGFP
ExpressionBacterialMutationS65A V68L S72AAvailable SinceMarch 5, 2009AvailabilityAcademic Institutions and Nonprofits only -
pGL2 HNF4A P2 mut
Plasmid#60325PurposeMutated HNF4A P2 promoter region cloned into the pGL2-basic backbone. The -181 G to A mutation is in a HNF1alpha binding site and cosegregates with MODY.DepositorInsertHNF4A P2 mut (-181 G to A) (HNF4A Human)
UseLuciferaseTagsLuciferaseExpressionMammalianMutationThe -181 G to A mutation is in a HNF1alpha bindin…Available SinceJan. 6, 2015AvailabilityAcademic Institutions and Nonprofits only -
pCMV_mApple-SEPT7 Gmut2
Plasmid#180317Purposemammalian expression of human SEPT7 Gmut2 fused to mAppleDepositorAvailable SinceDec. 1, 2022AvailabilityAcademic Institutions and Nonprofits only -
pCMV_msfGFP-SEPT7 Gmut2
Plasmid#180425Purposemammalian expression of human SEPT7 Gmut2 fused to monomeric superfolder GFPDepositorAvailable SinceDec. 1, 2022AvailabilityAcademic Institutions and Nonprofits only -
DBDmut-CA-RIT-NFAT1
Plasmid#63669PurposeConstitutively active NFAT1 and also unable to interact with AP-1 with four point mutations in the DNA binding loop that abolish DNA bindingDepositorInsertNFAT1 (Nfatc2 Mouse)
UseRetroviralTags3x HAExpressionMammalianMutationCA: PASSGSSASF mutated to PAAAGAAAAF, SPRTSPIMSP…Available SinceJuly 22, 2015AvailabilityAcademic Institutions and Nonprofits only -
pET30a-His6-LOXCATmut
Plasmid#140085PurposeA control for His6-LOXCAT where LOX is catalytically dead (mutations H265A and R268A)DepositorInsertA fusion of lactate oxidase from A. viridans and catalase from E. coli
TagsHis6ExpressionBacterialMutationMutation in H265A and R268A in LOX (used original…PromoterT7Available SinceSept. 16, 2020AvailabilityAcademic Institutions and Nonprofits only -
pCCL-GKL1ShortMutPRC-Ug1Lg2starTGA
Plasmid#52347PurposeIntegration cassette to create p1-Short-UL*(TGA)DepositorInsertleu*
UseP1 integration vectorExpressionBacterialMutationchanged S2F, A3V, Q180*PromoterUCS from pGKL2 ORF5Available SinceJune 17, 2014AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3.1+/mit-2mutAEQ
Plasmid#45539DepositorInsertmit-2mutAEQ
TagsMitochondrially targetedExpressionMammalianMutationAsp119Ala and Asn28LeuAvailable SinceJuly 3, 2013AvailabilityAcademic Institutions and Nonprofits only