We narrowed to 18,325 results for: MUT

1. pαH-S-GSAS/D614G

   Plasmid

   #164566

   Purpose

   SARS-CoV-2 Spike protein with D614G mutation (S-GSAS-D614G variant)

   Depositor

   Priyamvada Acharya

   Article

   Gobeil et al Cell Rep. 2021 Jan 12;34(2):108630. doi:

   Insert

   Spike (S-GSAS-D614G variant)
   

   Tags

   2X Strep-Tag II, 8X His tag, and HRV3C cleavage s…

   Expression

   Mammalian

   Mutation

   Ectodomain (AAs 1-1208); 682-685 (furin site = RR…

   Available Since

   Feb. 26, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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2. hV1aR-GFP

   Plasmid

   #67846

   Purpose

   mammalian expression of human V1a receptor with GFP tag

   Depositor

   Christian Gruber

   Article

   Koehbach et al Proc Natl Acad Sci U S A. 2013 Dec 24;11

   Insert

   V1a receptor (AVPR1A Human)
   

   Tags

   EGFP

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Oct. 15, 2015

   Availability

   Academic Institutions and Nonprofits only

3. hV1b-GFP-1

   Plasmid

   #67847

   Purpose

   mammalian expression of human V1b receptor with GFP tag

   Depositor

   Christian Gruber

   Article

   Koehbach et al Proc Natl Acad Sci U S A. 2013 Dec 24;11

   Insert

   V1b receptor (AVPR1B Human)
   

   Tags

   EGFP

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Oct. 15, 2015

   Availability

   Academic Institutions and Nonprofits only

4. pCAGGS-RaichuEV-Rac1(Y40C)

   Plasmid

   #164903

   Purpose

   Expresses a Rac1 FRET sensor RaichuEV-Rac1 which contains a dominant negative mutation Y40C in the Rac1 domain. More useful than T17N mutation due to less harmful to endogenous signaling.

   Depositor

   Takeshi Imai

   Article

   Aihara et al Cell Rep. 2021 Jun 22;35(12):109276. doi

   Insert

   RaichuEV-Rac1 (RAC1 Human)
   

   Expression

   Mammalian

   Mutation

   Y40C mutation in the Rac1 domain whcih make the s…

   Available Since

   Aug. 30, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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5. pL452-Sf3b1-K700E

   Plasmid

   #90425

   Purpose

   selectable HDR vector to introduce K700E mutation within mus Sf3b1 gene (for use with sgSf3b1(T1) and pL452(hygro)-Sf3b1-K700K plasmids enabling generation of hemizygous K700E mutation)

   Depositor

   Alex Minella

   Article

   Gupta et al Nucleic Acids Res. 2018 Nov 20. pii: 519

   Insert

   Sf3b1 - left and right homology arms (Sf3b1 Mouse)
   

   Use

   Homology-directed repair vector

   Available Since

   Nov. 26, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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6. pCDNA3-myc-his-BACH1 P47A

   Plasmid

   #17644

   Depositor

   Ronny Drapkin

   Article

   Cantor et al Proc Natl Acad Sci U S A. 2004 Feb 24. 1

   Insert

   BACH1 (BRIP1 Human)
   

   Tags

   His and Myc

   Expression

   Mammalian

   Mutation

   To generate the tumor-associated mutant, the prol…

   Available Since

   April 4, 2008

   Availability

   Academic Institutions and Nonprofits only

7. pMSCV-IRES-GFP/CALR del52-FLAG

   Plasmid

   #204523

   Purpose

   Retroviral expression of human CALR del52-FLAG

   Depositor

   Norio Komatsu

   Article

   Araki et al Blood. 2016 Jan 27. pii: blood-2015-09-6

   Insert

   CALR del52-FLAG (CALR Human)
   

   Use

   Retroviral

   Mutation

   del52

   Available Since

   Dec. 13, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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8. pMSCV-IRES-GFP/CALR ins5-FLAG

   Plasmid

   #204524

   Purpose

   Retroviral expression of human CALR ins5-FLAG

   Depositor

   Norio Komatsu

   Article

   Araki et al Blood. 2016 Jan 27. pii: blood-2015-09-6

   Insert

   CALR ins5-FLAG (CALR Human)
   

   Use

   Retroviral

   Mutation

   ins5

   Available Since

   Sept. 11, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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9. pCW57.1_SPTLC1_C133W

   Plasmid

   #181921

   Purpose

   3rd generation, Inducible lentiviral plasmid for expression of human mutant SPTLC1 C133W

   Depositor

   Christian Metallo

   Article

   Cordes et al J Lipid Res. 2022 Sep 14:100281. doi: 10

   Insert

   Human serine palmitoyltransferase, long chain base subunit 1 (SPTLC1) mutant C133W (SPTLC1 Human)
   

   Use

   Lentiviral; Mammalian expression, , doxycycline i…

   Expression

   Mammalian

   Mutation

   cysteine at position 133 of the coding region of …

   Promoter

   tight TRE promoter

   Available Since

   May 13, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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10. pCAD104_Asn152Ser_pCMV6Entry-hIRG1

    Plasmid

    #124877

    Purpose

    Expresses hCAD Asp152Ser mutant in mammalian cells

    Depositor

    Konrad Buessow

    Article

    Chen et al Proc Natl Acad Sci U S A. 2019 Sep 23. p

    Insert

    cis-aconitate decarboxylase (ACOD1 Human)
    

    Tags

    myc and FLAG tags

    Expression

    Mammalian

    Mutation

    mutated Asn152 to Ser

    Promoter

    CMV

    Available Since

    Sept. 16, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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11. pCAD64_pCMV6_Entry_hIrg1

    Plasmid

    #124879

    Purpose

    Expresses hCAD His103Ala mutant in mammalian cells

    Depositor

    Konrad Buessow

    Article

    Chen et al Proc Natl Acad Sci U S A. 2019 Sep 23. p

    Insert

    cis-aconitate decarboxylase (ACOD1 Human)
    

    Tags

    myc and FLAG tags

    Expression

    Mammalian

    Mutation

    mutated His103 to Ala

    Promoter

    CMV

    Available Since

    Sept. 16, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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12. pCAGGS-SARS2-S-FKO (C-flag)

    Plasmid

    #159364

    Purpose

    Mammalian expression of SARS-CoV-2 S protein (FKO: furin-cleavage site mutant) with the flag tag at C-terminus.

    Depositor

    Michael Farzan, Hyeryun Choe

    Article

    Zhang et al Nat Commun. 2020 Nov 26;11(1):6013. doi:

    Insert

    SARS-CoV-2 S protein (S SARS-CoV-2)
    

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    Furin-cleavage site mutation

    Promoter

    CMV

    Available Since

    Sept. 15, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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13. pCAGGS-SARS2-S-FKO (NC-flag)

    Plasmid

    #159363

    Purpose

    Mammalian expression of SARS-CoV-2 S protein (FKO: furin-cleavage site mutant) with the flag tag at N- and C-termini.

    Depositor

    Michael Farzan, Hyeryun Choe

    Article

    Zhang et al Nat Commun. 2020 Nov 26;11(1):6013. doi:

    Insert

    SARS-CoV-2 S protein (S SARS-CoV-2)
    

    Tags

    Flag and Flag

    Expression

    Mammalian

    Mutation

    Furin-cleavage site mutation

    Promoter

    CMV

    Available Since

    Sept. 15, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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14. pBABE-hygro-BAP1-C91S-HA

    Plasmid

    #154021

    Purpose

    Mammalian Expression of HA-tagged p.C91S Mutant BAP1

    Depositor

    Samuel Peña-Llopis

    Article

    Niersch et al iScience. 2021 Feb 12;24(3):102173. doi:

    Insert

    BAP1 (BAP1 Human)
    

    Use

    Retroviral

    Tags

    Hemagglutinin (HA)

    Expression

    Mammalian

    Mutation

    p.C91S (Missense Mutation, Catalytically Inactive)

    Available Since

    Feb. 12, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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15. Cav2.1 EA2, R57A, R59A pMT2

    Plasmid

    #206122

    Purpose

    expression of rabbit Cav2.1 calcium channel with a CaV2.1-P1217fs mutation causing a truncated protein, (EA2). R57A R59A mutations prevent dominant-negative suppression of Cav2.1 currents

    Depositor

    Annette Dolphin

    Article

    Dahimene et al Neurobiol Dis. 2016 Sep;93:243-56. doi:

    Insert

    cacna1a (Cacna1a Rat)
    

    Expression

    Mammalian

    Mutation

    Cav2.1-P1217fs, R57A, R59A

    Promoter

    Ad MLP/TPL/SV40

    Available Since

    Nov. 28, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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16. pCAD54_CAD29_H104A_pvp008

    Plasmid

    #124876

    Purpose

    Expresses hCAD His103Ala mutant in E.coli

    Depositor

    Konrad Buessow

    Article

    Chen et al Proc Natl Acad Sci U S A. 2019 Sep 23. p

    Insert

    cis-aconitate decarboxylase (ACOD1 Human)
    

    Tags

    StrepTag and TEV site

    Expression

    Bacterial

    Mutation

    mutated His103 to Ala, deleted amino acids 1-3 an…

    Promoter

    T7

    Available Since

    Sept. 16, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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17. pCAD108_Arg273His_pCMV6Entry-hIRG1

    Plasmid

    #124878

    Purpose

    Expresses hCAD Arg273His mutant in mammalian cells

    Depositor

    Konrad Buessow

    Article

    Chen et al Proc Natl Acad Sci U S A. 2019 Sep 23. p

    Insert

    cis-aconitate decarboxylase (ACOD1 Human)
    

    Tags

    myc and FLAG tags

    Expression

    Mammalian

    Mutation

    mutated Arg273 to His

    Promoter

    CMV

    Available Since

    Sept. 23, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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18. pCAD96_hIRG1_4-461_pvp008

    Plasmid

    #124874

    Purpose

    Expresses hCAD Asn152Ser mutant in E.coli

    Depositor

    Konrad Buessow

    Article

    Chen et al Proc Natl Acad Sci U S A. 2019 Sep 23. p

    Insert

    cis-aconitate decarboxylase (ACOD1 Human)
    

    Tags

    StrepTag and TEV site

    Expression

    Bacterial

    Mutation

    mutated Asn152 to Ser, deleted amino acids 1-3 an…

    Promoter

    T7

    Available Since

    Oct. 2, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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19. pJL388

    Plasmid

    #243717

    Purpose

    Stably expresses a Myc-tagged AKAP1 with a GDDG mutation and gRNA-resistant silent mutations

    Depositor

    Jonathan Weissman

    Article

    Luo et al Cell. 2025 Aug 25:S0092-8674(25)00916-X.

    Insert

    AKAP1 (AKAP1 Human)
    

    Use

    Lentiviral

    Tags

    Myc

    Mutation

    GXXG motif (GKQG 624-627) mutated to GDDG, and gR…

    Available Since

    Oct. 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. HR700_HA2TP53_Ex5

    Plasmid

    #228860

    Purpose

    Backbone for generation of donor vectors for CRISPR/Cas9 mediated Saturation Genome Editing (SGE) of TP53 Exon 5

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Type

    Empty backbone

    Use

    CRISPR and Cre/Lox

    Expression

    Mammalian

    Available Since

    Feb. 4, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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