We narrowed to 66 results for: human sgrna library

1. Human sgRNA library Brunello in lentiCRISPRv2

   Pooled Library

   #73179

   Purpose

   Human sgRNA library in backbone lentiCRISPRv2 targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

2. Human messenger-RBP sgRNA library

   Pooled Library

   #168791

   Purpose

   CRISPR library targets sub-pool of human mRNA binding proteins

   Depositor

   Martin Turner

   Article

   Turner et al CRISPR J. 2021 Jun;4(3):427-437. doi: 10

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   July 30, 2021

   Availability

   Academic Institutions and Nonprofits only

3. Human Lentiviral sgRNA Library - Kinases

   Pooled Library

   #51044

   Purpose

   Sub-pool of Sabatini/Lander sgRNA library enriched for kinase targets.

   Depositor

   David Sabatini, Eric Lander

   Article

   Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 7, 2014

   Availability

   Academic Institutions and Nonprofits only

4. Human Lentiviral sgRNA Library - Nuclear

   Pooled Library

   #51047

   Purpose

   Sub-pool of Sabatini/Lander sgRNA library enriched for nuclear targets.

   Depositor

   David Sabatini, Eric Lander

   Article

   Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 7, 2014

   Availability

   Academic Institutions and Nonprofits only

5. Human Lentiviral sgRNA Library - Control

   Pooled Library

   #51048

   Purpose

   Sub-pool of Sabatini/Lander sgRNA library enriched for control targets.

   Depositor

   David Sabatini, Eric Lander

   Article

   Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 7, 2014

   Availability

   Academic Institutions and Nonprofits only

6. Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in pLenti-sgRNA

   Pooled Library

   #1000000095

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human genome

   Depositor

   David Sabatini, Eric Lander

   Available since

   April 3, 2017

   Availability

   Academic Institutions and Nonprofits only

7. Human sgRNA library Brunello in lentiGuide-Puro

   Pooled Library

   #73178

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

8. Human GeCKO Lentiviral sgRNA Library v2 (LentiCRISPR)

   Pooled Library

   #1000000048

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human genome

   Depositor

   Feng Zhang

   Available since

   May 8, 2014

   Availability

   Academic Institutions and Nonprofits only

9. Human sgRNA library Gattinara in pRDA_118 backbone

   Pooled Library

   #136986

   Purpose

   Expresses sgRNAs targeting human genes

   Depositor

   John Doench

   Article

   DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 24, 2020

   Availability

   Academic Institutions and Nonprofits only

10. Human Metabolic Gene CRISPRa sgRNA library

    Pooled Library

    #187080

    Purpose

    Lentiviral CRISPRa library targeting human metabolic genes for activation of gene expression

    Depositor

    Kivanc Birsoy

    Article

    Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Oct. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

11. Human Lentiviral sgRNA Library - Cell Cycle

    Pooled Library

    #51046

    Purpose

    Sub-pool of Sabatini/Lander sgRNA library enriched for cell cycle-related targets.

    Depositor

    David Sabatini, Eric Lander

    Article

    Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 7, 2014

    Availability

    Academic Institutions and Nonprofits only

12. Human Lentiviral sgRNA Library - Ribosomal Proteins

    Pooled Library

    #51045

    Purpose

    Sub-pool of Sabatini/Lander sgRNA library enriched for ribosomal gene targets.

    Depositor

    David Sabatini, Eric Lander

    Article

    Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 7, 2014

    Availability

    Academic Institutions and Nonprofits only

13. Human Lentiviral sgRNA Library - Unknown Function

    Pooled Library

    #51043

    Purpose

    Sub-pool of Sabatini/Lander sgRNA library enriched for gene targets of unknown function.

    Depositor

    David Sabatini, Eric Lander

    Article

    Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 7, 2014

    Availability

    Academic Institutions and Nonprofits only

14. Human Whole Genome sgRNA iBAR Library

    Pooled Library

    #140633

    Purpose

    CRISPR pooled screen at high MOI by the embedded internal barcodes

    Depositor

    Wensheng Wei

    Article

    Zhu et al Genome Biol. 2019 Jan 24;20(1):20. doi:

    Use

    CRISPR and Lentiviral

    Available since

    April 21, 2020

    Availability

    Academic Institutions and Nonprofits only

15. Human CRISPRi sgRNA library Dolcetto in backbone XPR_050

    Pooled Library

    #1000000114

    Purpose

    Genome-wide CRISPR gRNA pooled library for inhibition of human genes

    Depositor

    David Root, John Doench

    Available since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

16. Human GeCKO Lentiviral sgRNA Library v2 (lentiGuide-Puro)

    Pooled Library

    #1000000049

    Purpose

    CRISPR gRNA knockout pooled library for targeting the human genome

    Depositor

    Feng Zhang

    Available since

    May 8, 2014

    Availability

    Academic Institutions and Nonprofits only

17. Human SAM library in lenti sgRNA(MS2)_puro backbone

    Pooled Library

    #1000000074

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of mouse genes

    Depositor

    Feng Zhang

    Available since

    March 17, 2016

    Availability

    Academic Institutions and Nonprofits only

18. Human SAM Library in lenti sgRNA(MS2)_zeo backbone

    Pooled Library

    #1000000057

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of human genes

    Depositor

    Feng Zhang

    Available since

    Jan. 16, 2015

    Availability

    Academic Institutions and Nonprofits only

19. Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set A

    Pooled Library

    #92385

    Purpose

    Crispri

    Depositor

    David Root, John Doench

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Has Service

    Lentiviral Prep

    Use

    Lentiviral

    Available since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

20. Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set B

    Pooled Library

    #92386

    Purpose

    Crispri

    Depositor

    David Root, John Doench

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Use

    Lentiviral

    Available since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

21. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF)

    Pooled Library

    #1000000111

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of human genes

    Depositor

    David Root, John Doench

    Available since

    Aug. 3, 2017

    Availability

    Academic Institutions and Nonprofits only

22. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set B

    Pooled Library

    #92380

    Purpose

    CRISPRa

    Depositor

    David Root, John Doench

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Use

    Lentiviral

    Available since

    Aug. 3, 2017

    Availability

    Academic Institutions and Nonprofits only

23. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set A

    Pooled Library

    #92379

    Purpose

    CRISPRa

    Depositor

    David Root, John Doench

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Has Service

    Lentiviral Prep

    Use

    Lentiviral

    Available since

    Aug. 3, 2017

    Availability

    Academic Institutions and Nonprofits only

24. Compact mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

    Pooled Library

    #136479

    Purpose

    Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

    Depositor

    Jonathan Weissman

    Article

    Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

25. Human CRISPR lncRNA activation library (SAM) in lenti sgRNA(MS2)_zeo backbone

    Pooled Library

    #1000000106

    Purpose

    Human CRISPR Synergistic Activation Mediator (SAM) pooled library for the transcriptional activation of lncRNAs

    Depositor

    Feng Zhang

    Available since

    June 5, 2017

    Availability

    Academic Institutions and Nonprofits only

26. Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in lentiCRISPR v1

    Pooled Library

    #1000000100

    Purpose

    CRISPR gRNA knockout pooled library (version 1) for targeting the human genome

    Depositor

    David Sabatini, Eric Lander

    Available since

    April 3, 2017

    Availability

    Academic Institutions and Nonprofits only

27. Large-scale mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

    Pooled Library

    #136478

    Purpose

    Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

    Depositor

    Jonathan Weissman

    Article

    Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

28. Sabatini/Lander Lab Ras synthetic lethal candidate focused human sgRNA library in lentiCRISPRv1

    Pooled Library

    #92352

    Purpose

    contains 6,661 sgRNAs (comprising 499 intergenic control sgRNAs and 6,162 sgRNAs targeting 132 control and candidate Ras synthetic lethal genes at up to 50 sgRNAs per gene)

    Depositor

    David Sabatini, Eric Lander

    Article

    Wang et al Cell. 2017 Feb 1. pii: S0092-8674(17)300

    Species

    Homo sapiens

    Available since

    June 7, 2017

    Availability

    Academic Institutions and Nonprofits only

29. The Human Druggable CRISPR library

    Pooled Library

    #200013

    Purpose

    The library contains ~10,000 sgRNAs targeting 1,980 human genes (5 sgRNAs per gene and 100 nontargeting control sgRNAs).

    Depositor

    Lianxin Liu

    Article

    Zheng et al Adv Sci (Weinh). 2023 Aug;10(22):e220679

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    May 9, 2023

    Availability

    Academic Institutions and Nonprofits only

30. Human Brunello kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

    Pooled Library

    #75314

    Purpose

    Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only