We narrowed to 279 results for: CaS;

1. Lourido Toxoplasma CRISPR Library V1

   Pooled Library

   #80636

   Purpose

   Plasmid sgRNA library containing ten guides against each of the 8,158 predicted Toxoplasma gondii protein coding genes.

   Depositor

   Sebastian Lourido

   Article

   Sidik et al Cell. 2016 Sep 8;166(6):1423-1435.e12. d

   Available Since

   Sept. 19, 2016

   Availability

   Academic Institutions and Nonprofits only

2. Human Transporter Knockout Library with UMIs

   Pooled Library

   #221409

   Purpose

   gRNA library to test the impact of transporters on biological processes

   Depositor

   Giulio Superti-Furga, RESOLUTE Consortium

   Article

   Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Sept. 13, 2024

   Availability

   Academic Institutions and Nonprofits only

3. EFS-mTSG

   Pooled Library

   #113584

   Purpose

   AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes

   Depositor

   Sidi Chen

   Article

   Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

   Expression

   Mammalian

   Use

   AAV, CRISPR, Lentiviral, and Luciferase

   Available Since

   July 23, 2019

   Availability

   Academic Institutions and Nonprofits only

4. mTORC1 Focused library

   Pooled Library

   #164084

   Purpose

   Lentiviral CRISPR library targets human mTORC1 signaling pathway

   Depositor

   David Sabatini

   Article

   Condon et al Proc Natl Acad Sci U S A. 2021 Jan 26;11

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Jan. 11, 2021

   Availability

   Academic Institutions and Nonprofits only

5. Oxford Drosophila melanogaster Genome-wide CRISPR Library

   Pooled Library

   #64750

   Purpose

   A genome-wide CRISPR library covering 13,501 genes (98.8% of the Drosophila melanogaster genome), among which 8,989 genes are targeted by three or more independent single guide RNAs (sgRNAs).

   Depositor

   Ji-Long Liu

   Article

   Bassett et al J Genet Genomics. 2015 Jun 20;42(6):301-

   Expression

   Insect

   Species

   Drosophila melanogaster, Streptococcus pyogenes, and Synthetic

   Use

   CRISPR

   Available Since

   March 7, 2016

   Availability

   Academic Institutions and Nonprofits only

6. DNA repair library with 336 sgRNAs

   Pooled Library

   #177664

   Purpose

   CRISPR-interference (CRISPRi) library of 366 sgRNAs targeting 118 genes encoding factors involved in DNA repair and associated processes

   Depositor

   Brittany Adamson

   Article

   Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

   Species

   Homo sapiens

   Use

   CRISPR

   Available Since

   Nov. 29, 2023

   Availability

   Academic Institutions and Nonprofits only

7. mU6-CR1-CRISPRiv2_hU6-CR3-NT-ctrl-guide_EF1a-PuroR-T2A-BFP

   Pooled Library

   #197348

   Purpose

   To allow for genome-wide genetic modifier screening, the library has a second fixed non-targeting control guide.

   Depositor

   Rebecca Voorhees, Jonathan Weissman

   Article

   Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

   Species

   Homo sapiens

   Use

   Lentiviral

   Available Since

   May 25, 2023

   Availability

   Academic Institutions and Nonprofits only

8. CHyMErA Paralog&Dual-targeting hgRNA Library

   Pooled Library

   #155199

   Purpose

   Hybrid guide RNA library targetings human paralog pairs and other protein-coding genes.

   Depositor

   Benjamin Blencowe, Jason Moffat

   Article

   Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   Sept. 2, 2020

   Availability

   Academic Institutions and Nonprofits only

9. RNA-binding protein pooled CRISPR knockout library

   Pooled Library

   #141438

   Purpose

   CRISPR knockout library targets RBPs with 10 sgRNAs/gene

   Depositor

   Eugene Yeo

   Article

   Wheeler et al Nat Methods. 2020 May 11. pii: 10.1038/s

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   May 28, 2020

   Availability

   Academic Institutions and Nonprofits only

10. The Human Druggable CRISPR library

    Pooled Library

    #200013

    Purpose

    The library contains ~10,000 sgRNAs targeting 1,980 human genes (5 sgRNAs per gene and 100 nontargeting control sgRNAs).

    Depositor

    Lianxin Liu

    Article

    Zheng et al Adv Sci (Weinh). 2023 Aug;10(22):e220679

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    May 9, 2023

    Availability

    Academic Institutions and Nonprofits only

11. hCRISPRi_dual_1_2

    Pooled Library

    #187246

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available Since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

12. Mouse lipid metabolism knockout library

    Pooled Library

    #206248

    Purpose

    The lipid metabolism library contains guide RNAs against 295 genes targeting mouse genes encoding enzymes that directly impact lipid metabolism.

    Depositor

    Kivanc Birsoy

    Article

    Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

13. hCRISPRa_dual_1_2

    Pooled Library

    #187249

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available Since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

14. hCRISPRi_dual_5_6

    Pooled Library

    #187248

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available Since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

15. TBG-mTSG

    Pooled Library

    #113585

    Purpose

    AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes in mouse liver

    Depositor

    Sidi Chen

    Article

    Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

    Expression

    Mammalian

    Use

    AAV, CRISPR, Lentiviral, and Luciferase

    Available Since

    July 23, 2019

    Availability

    Academic Institutions and Nonprofits only

16. CRISPRi non-coding library (CRiNCL) - Unique to HEK293T

    Pooled Library

    #86543

    Depositor

    Jonathan Weissman

    Article

    Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

    Available Since

    March 8, 2017

    Availability

    Academic Institutions and Nonprofits only

17. CRISPRi non-coding library (CRiNCL) - iPSC & HFF

    Pooled Library

    #86550

    Depositor

    Jonathan Weissman

    Article

    Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

    Available Since

    March 8, 2017

    Availability

    Academic Institutions and Nonprofits only

18. CRISPRi non-coding library (CRiNCL) - Unique to K562

    Pooled Library

    #86544

    Depositor

    Jonathan Weissman

    Article

    Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

    Available Since

    March 8, 2017

    Availability

    Academic Institutions and Nonprofits only

19. CRISPRi non-coding library (CRiNCL) - Unique to HFF

    Pooled Library

    #86541

    Depositor

    Jonathan Weissman

    Article

    Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

    Available Since

    March 8, 2017

    Availability

    Academic Institutions and Nonprofits only

20. hCRISPRi_dual_3_4

    Pooled Library

    #187247

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available Since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only