We narrowed to 358 results for: Library

1. Mouse sphingolipid metabolism knockout library

   Pooled Library

   #206249

   Purpose

   The sphingolipid metabolism library targets 82 mouse genes in the de novo ceramide and downstream sphingolipid metabolism pathways.

   Depositor

   Kivanc Birsoy

   Article

   Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

   Use

   CRISPR and Lentiviral

   Available Since

   Aug. 29, 2024

   Availability

   Academic Institutions and Nonprofits only

2. Mouse lipid metabolism knockout library

   Pooled Library

   #206248

   Purpose

   The lipid metabolism library contains guide RNAs against 295 genes targeting mouse genes encoding enzymes that directly impact lipid metabolism.

   Depositor

   Kivanc Birsoy

   Article

   Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

   Use

   CRISPR and Lentiviral

   Available Since

   Aug. 29, 2024

   Availability

   Academic Institutions and Nonprofits only

3. DNA repair library with 1,573 sgRNAs

   Pooled Library

   #177663

   Purpose

   CRISPR-interference (CRISPRi) library of 1,573 sgRNAs targeting 476 genes encoding factors involved in DNA repair and associated processes

   Depositor

   Brittany Adamson

   Article

   Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

   Species

   Homo sapiens

   Use

   CRISPR

   Available Since

   July 11, 2023

   Availability

   Academic Institutions and Nonprofits only

4. Human Lentiviral sgRNA Library - Kinases

   Pooled Library

   #51044

   Purpose

   Sub-pool of Sabatini/Lander sgRNA library enriched for kinase targets.

   Depositor

   Eric Lander, David Sabatini

   Article

   Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 7, 2014

   Availability

   Academic Institutions and Nonprofits only

5. Mouse messenger-RBP sgRNA library

   Pooled Library

   #169082

   Purpose

   CRISPR library targeting mouse genes

   Depositor

   Martin Turner

   Article

   Turner et al eLife. 2022 Apr 22;11. pii: 72313. doi:

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available Since

   Sept. 10, 2021

   Availability

   Academic Institutions and Nonprofits only

6. Human Lentiviral sgRNA Library - Nuclear

   Pooled Library

   #51047

   Purpose

   Sub-pool of Sabatini/Lander sgRNA library enriched for nuclear targets.

   Depositor

   Eric Lander, David Sabatini

   Article

   Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 7, 2014

   Availability

   Academic Institutions and Nonprofits only

7. Human Base Editing Sensor Library

   Pooled Library

   #179218

   Purpose

   sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

   Depositor

   Lukas Dow

   Article

   Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

   Expression

   Mammalian

   Use

   Lentiviral

   Available Since

   June 16, 2022

   Availability

   Academic Institutions and Nonprofits only

8. DNA repair library with 1,513 sgRNAs

   Pooled Library

   #177670

   Purpose

   CRISPR-interference (CRISPRi) library designed to target 476 genes involved in DNA repair and associated processes. It contains 1,513 sgRNAs and 60 non-targeting control sgRNAs.

   Depositor

   Brittany Adamson

   Article

   Chen et al Cell. 2021 Oct 28;184(22):5635-5652.e29.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   July 11, 2023

   Availability

   Academic Institutions and Nonprofits only

9. Mouse Validation (mVAL) CRISPR Library

   Pooled Library

   #159391

   Purpose

   Pooled CRISPR library targets core intrinsic immune evasion genes

   Depositor

   Jason Moffat

   Article

   Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available Since

   Nov. 9, 2020

   Availability

   Academic Institutions and Nonprofits only

10. Human messenger-RBP sgRNA library

    Pooled Library

    #168791

    Purpose

    CRISPR library targets sub-pool of human mRNA binding proteins

    Depositor

    Martin Turner

    Article

    Turner et al CRISPR J. 2021 Jun;4(3):427-437. doi: 10

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    July 30, 2021

    Availability

    Academic Institutions and Nonprofits only

11. Self-targeting epegRNA library, +5 G>H (lDS004)

    Pooled Library

    #227707

    Purpose

    CRISPR guide RNA library for prime editing

    Depositor

    Brittany Adamson

    Article

    Cirincione et al Nat Methods. 2024 Nov 19. doi: 10.1038/s

    Expression

    Mammalian

    Use

    Lentiviral

    Available Since

    Jan. 23, 2025

    Availability

    Academic Institutions and Nonprofits only

12. Human Lentiviral sgRNA Library - Control

    Pooled Library

    #51048

    Purpose

    Sub-pool of Sabatini/Lander sgRNA library enriched for control targets.

    Depositor

    Eric Lander, David Sabatini

    Article

    Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Feb. 7, 2014

    Availability

    Academic Institutions and Nonprofits only

13. Mouse Liver CRISPR Knockout Library

    Pooled Library

    #192824

    Purpose

    CRISPR screening library containing ~72,000 sgRNAs

    Depositor

    Kristin Knouse

    Article

    Keys et al Cell Genom. 2022 Dec 14;2(12):100217. do

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available Since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

14. Mouse Base Editing Sensor Library

    Pooled Library

    #179217

    Purpose

    sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

    Depositor

    Lukas Dow

    Article

    Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

    Expression

    Mammalian

    Use

    Lentiviral

    Available Since

    June 16, 2022

    Availability

    Academic Institutions and Nonprofits only

15. Human Paralog Knockout Library (pgPEN)

    Pooled Library

    #171172

    Purpose

    CRISPR library targets human duplicate paralog gene pairs

    Depositor

    Alice Berger

    Article

    Parrish et al Cell Rep. 2021 Aug 31;36(9):109597. doi:

    Expression

    Mammalian

    Species

    Homo sapiens and Synthetic

    Use

    CRISPR and Lentiviral

    Available Since

    Sept. 28, 2021

    Availability

    Academic Institutions and Nonprofits only

16. Human Transporter Knockout Library with UMIs

    Pooled Library

    #221409

    Purpose

    gRNA library to test the impact of transporters on biological processes

    Depositor

    Giulio Superti-Furga, RESOLUTE Consortium

    Article

    Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Sept. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

17. S. rosetta Col- cDNA amplified library

    Pooled Library

    #62843

    Purpose

    amplified library of Salpingoeca rosetta

    Depositor

    Nicole King

    Article

    Fairclough et al Genome Biol. 2013 Feb 18;14(2):R15. doi:

    Expression

    Bacterial

    Species

    Salpingoeca rosetta

    Available Since

    June 16, 2015

    Availability

    Academic Institutions and Nonprofits only

18. S. rosetta Col+ cDNA amplified library

    Pooled Library

    #62844

    Purpose

    amplified library of Salpingoeca rosetta from a colony rich culture which included the colony inducing bacteria Algoriphagus machipongonensis

    Depositor

    Nicole King

    Article

    Fairclough et al Genome Biol. 2013 Feb 18;14(2):R15. doi:

    Expression

    Bacterial

    Species

    Salpingoeca rosetta

    Available Since

    June 16, 2015

    Availability

    Academic Institutions and Nonprofits only

19. SARS-CoV-2 Spike (S) Ectodomain Library C

    Pooled Library

    #157973

    Purpose

    Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Bacterial and Yeast

    Species

    Sars-cov-2

    Available Since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

20. SARS-CoV-2 Spike (S) Ectodomain Library B

    Pooled Library

    #157972

    Purpose

    Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Bacterial and Yeast

    Species

    Sars-cov-2

    Available Since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only