We narrowed to 166 results for: Ide

1. Humagne Set D

   Pooled Library

   #172651

   Purpose

   Set D contains best-ranked guides 2 and 3.

   Depositor

   John Doench, David Root

   Article

   DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

   Expression

   Mammalian

   Available Since

   Nov. 10, 2021

   Availability

   Academic Institutions and Nonprofits only

2. Self-targeting epegRNA library, +5 G>H (lDS004)

   Pooled Library

   #227707

   Purpose

   CRISPR guide RNA library for prime editing

   Depositor

   Brittany Adamson

   Article

   Cirincione et al Nat Methods. 2024 Nov 19. doi: 10.1038/s

   Expression

   Mammalian

   Use

   Lentiviral

   Available Since

   Jan. 23, 2025

   Availability

   Academic Institutions and Nonprofits only

3. StopPR epegRNA library (lAC002)

   Pooled Library

   #227706

   Purpose

   CRISPR guide RNA library for prime editing

   Depositor

   Brittany Adamson

   Article

   Cirincione et al Nat Methods. 2024 Nov 19. doi: 10.1038/s

   Expression

   Mammalian

   Use

   Lentiviral

   Available Since

   Jan. 23, 2025

   Availability

   Academic Institutions and Nonprofits only

4. Pan-cancer CasRx lncRNA Albarossa library

   Pooled Library

   #212966

   Purpose

   The human CasRx CRISPR lentiviral library encodes 75,725 gRNA arrays (two gRNAs per array) targeting 24,171 lncRNAs.

   Depositor

   Roland Rad

   Article

   Montero et al Nat Methods. 2024 Feb 26. doi: 10.1038/s

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

5. Lenti-human-TF-gRNA-puromycin

   Pooled Library

   #162275

   Purpose

   This is a gRNA library targeting on ~1600 human transcription factors for genetic screening.

   Depositor

   Chunliang Li

   Article

   Zhang et al Elife. 2020 Oct 1;9. pii: 57858. doi: 10

   Species

   Homo sapiens

   Use

   Lentiviral

   Available Since

   Dec. 15, 2020

   Availability

   Academic Institutions and Nonprofits only

6. Mouse sphingolipid metabolism knockout library

   Pooled Library

   #206249

   Purpose

   The sphingolipid metabolism library targets 82 mouse genes in the de novo ceramide and downstream sphingolipid metabolism pathways.

   Depositor

   Kivanc Birsoy

   Article

   Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

   Use

   CRISPR and Lentiviral

   Available Since

   Aug. 29, 2024

   Availability

   Academic Institutions and Nonprofits only

7. Pdest-EF1α-EGFP-32bp barcode polyA library

   Pooled Library

   #211610

   Purpose

   Barcoded retrovirus plasmid library for capturing the transcriptome and viral barcode sequences of individual cells to infer their identities and lineage information.

   Depositor

   Yuejun Chen

   Article

   You et al Cell Stem Cell. 2023 Apr 6;30(4):473-487

   Species

   Synthetic

   Use

   Retroviral

   Available Since

   Aug. 29, 2024

   Availability

   Academic Institutions and Nonprofits only

8. pCMV-Rep78/68 Scanning Saturation Mutagenesis (SSM)

   Pooled Library

   #198050

   Purpose

   By supplying an AAV cap gene of interest in trans, researchers can use this library to investigate the effects of rep mutations on production of a wide range of AAV capsid serotypes

   Depositor

   George Church

   Article

   Jain et al Elife. 2024 Mar 27;12:RP87730. doi: 10.7

   Expression

   Mammalian

   Use

   AAV

   Available Since

   May 4, 2023

   Availability

   Academic Institutions and Nonprofits only

9. Human Paralog Knockout Library (pgPEN)

   Pooled Library

   #171172

   Purpose

   CRISPR library targets human duplicate paralog gene pairs

   Depositor

   Alice Berger

   Article

   Parrish et al Cell Rep. 2021 Aug 31;36(9):109597. doi:

   Expression

   Mammalian

   Species

   Homo sapiens and Synthetic

   Use

   CRISPR and Lentiviral

   Available Since

   Sept. 28, 2021

   Availability

   Academic Institutions and Nonprofits only

10. Self-targeting epegRNA library, Tiled edits (lRM001)

    Pooled Library

    #227708

    Purpose

    CRISPR guide RNA library for prime editing

    Depositor

    Brittany Adamson

    Article

    Cirincione et al Nat Methods. 2024 Nov 19. doi: 10.1038/s

    Expression

    Mammalian

    Use

    Lentiviral

    Available Since

    Jan. 23, 2025

    Availability

    Academic Institutions and Nonprofits only

11. Inzolia library in pRDA_550

    Pooled Library

    #209552

    Purpose

    The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

    Depositor

    John Doench

    Article

    Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

    Use

    CRISPR and Lentiviral

    Available Since

    Dec. 5, 2023

    Availability

    Academic Institutions and Nonprofits only

12. hCRISPRi_dual_1_2

    Pooled Library

    #187246

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available Since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

13. Mouse lipid metabolism knockout library

    Pooled Library

    #206248

    Purpose

    The lipid metabolism library contains guide RNAs against 295 genes targeting mouse genes encoding enzymes that directly impact lipid metabolism.

    Depositor

    Kivanc Birsoy

    Article

    Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

14. hCRISPRa_dual_1_2

    Pooled Library

    #187249

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available Since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

15. FNLCR CRISPRa Cell Surface

    Pooled Library

    #207471

    Purpose

    CRISPR-based activation library with guide RNAs targeting all cell surface proteins.

    Depositor

    Raj Chari

    Article

    Yang et al Sci Adv. 2024 Feb 16;10(7):eadj2445. doi

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Jan. 24, 2024

    Availability

    Academic Institutions and Nonprofits only

16. hCRISPRi_dual_5_6

    Pooled Library

    #187248

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available Since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

17. hCRISPRi_dual_3_4

    Pooled Library

    #187247

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available Since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

18. hCRISPRa_dual_3_4

    Pooled Library

    #187250

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available Since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

19. hCRISPRa_dual_5_6

    Pooled Library

    #187251

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available Since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

20. Human CRISPR Poison Exon Knockout Library

    Pooled Library

    #138084

    Purpose

    The human pgPoison library induces skipping of “poison” cassette exons and corresponding upstream constitutive exons by targeting 3' splice sites with paired gRNAs (pgRNAs).

    Depositor

    Robert Bradley

    Article

    Thomas et al Nat Genet. 2020 Jan;52(1):84-94. doi: 10

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    March 6, 2020

    Availability

    Academic Institutions and Nonprofits only