Addgene

We narrowed to 275 results for: Spr;

Showing: 161 - 180 of 275 results

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psgRNA Library

Pooled Library

#115927

Purpose

Genome-wide knockdown of E. coli genes

Depositor

David Bikard

Article

Cui et al Nat Commun. 2018 May 15;9(1):1912. doi:

Expression

Bacterial

Species

Escherichia coli

Use

CRISPR

Available since

June 6, 2019

Availability

Academic Institutions and Nonprofits only
psgRNA_EcoWG1

Pooled Library

#131625

Purpose

Improved genome-wide knockdown of E. coli genes

Depositor

David Bikard

Article

Calvo-Villamanan et al Nucleic Acids Res. 2020 Apr 30. pii: 582

Expression

Bacterial

Species

Escherichia coli

Use

CRISPR

Available since

May 12, 2020

Availability

Academic Institutions and Nonprofits only
Drosophila_sgRNA_group_3

Pooled Library

#134584

Purpose

Targets all other Drosophila genes not included in Groups 1 and 2

Depositor

Norbert Perrimon

Article

Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

Expression

Insect

Species

Drosophila melanogaster

Use

CRISPR

Available since

Feb. 25, 2020

Availability

Academic Institutions and Nonprofits only
Drosophila_sgRNA_group_1

Pooled Library

#134582

Purpose

Targets kinases, phosphatases, and Drosophila orthologs of drug targets

Depositor

Norbert Perrimon

Article

Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

Expression

Insect

Species

Drosophila melanogaster

Use

CRISPR

Available since

Feb. 25, 2020

Availability

Academic Institutions and Nonprofits only
Drosophila_sgRNA_group_2

Pooled Library

#134583

Purpose

Targets Drosophila orthologs of vertebrate genes that have undergone expansion in the vertebrate line

Depositor

Norbert Perrimon

Article

Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

Expression

Insect

Species

Drosophila melanogaster

Use

CRISPR

Available since

Feb. 25, 2020

Availability

Academic Institutions and Nonprofits only
Mouse Metabolism Library

Pooled Library

#163966

Purpose

Lentiviral CRISPR library targets 2,918 mouse metabolic genes with ~18,000 guide RNAs. The library contains ~6 gRNAs per gene.

Depositor

Alec Kimmelman

Article

Biancur et al Cell Metab. 2020 Oct 28. pii: S1550-4131

Use

CRISPR and Lentiviral

Available since

July 1, 2021

Availability

Academic Institutions and Nonprofits only
Human Lentiviral sgRNA Library - Kinases

Pooled Library

#51044

Purpose

Sub-pool of Sabatini/Lander sgRNA library enriched for kinase targets.

Depositor

Eric Lander, David Sabatini

Article

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Feb. 7, 2014

Availability

Academic Institutions and Nonprofits only
Human Lentiviral sgRNA Library - Nuclear

Pooled Library

#51047

Purpose

Sub-pool of Sabatini/Lander sgRNA library enriched for nuclear targets.

Depositor

Eric Lander, David Sabatini

Article

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Feb. 7, 2014

Availability

Academic Institutions and Nonprofits only
Human Lentiviral sgRNA Library - Cell Cycle

Pooled Library

#51046

Purpose

Sub-pool of Sabatini/Lander sgRNA library enriched for cell cycle-related targets.

Depositor

Eric Lander, David Sabatini

Article

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Feb. 7, 2014

Availability

Academic Institutions and Nonprofits only
Human Lentiviral sgRNA Library - Control

Pooled Library

#51048

Purpose

Sub-pool of Sabatini/Lander sgRNA library enriched for control targets.

Depositor

Eric Lander, David Sabatini

Article

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Feb. 7, 2014

Availability

Academic Institutions and Nonprofits only
Human Lentiviral sgRNA Library - Ribosomal Proteins

Pooled Library

#51045

Purpose

Sub-pool of Sabatini/Lander sgRNA library enriched for ribosomal gene targets.

Depositor

Eric Lander, David Sabatini

Article

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Feb. 7, 2014

Availability

Academic Institutions and Nonprofits only
Human Lentiviral sgRNA Library - Unknown Function

Pooled Library

#51043

Purpose

Sub-pool of Sabatini/Lander sgRNA library enriched for gene targets of unknown function.

Depositor

Eric Lander, David Sabatini

Article

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Feb. 7, 2014

Availability

Academic Institutions and Nonprofits only
pRG01-MCAP_MET

Pooled Library

#123361

Purpose

pRG01 with barcoded MCAP_Met crRNA array library cloned in, targeting combinations of metastasis drivers.

Depositor

Sidi Chen

Article

Chow et al Nat Methods. 2019 May;16(5):405-408. doi

Expression

Mammalian

Species

Synthetic

Use

CRISPR and Lentiviral

Available since

June 10, 2019

Availability

Academic Institutions and Nonprofits only
Human Transporter Knockout library

Pooled Library

#213695

Purpose

Next generation transporter-focused CRISPR/Cas9 library targeting transmembrane transporters to test the impact of transporters on biological processes.

Depositor

Giulio Superti-Furga, RESOLUTE Consortium

Article

Ferdigg et al Life Sci Alliance. 2024 Nov 22;8(2):e202

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Sept. 13, 2024

Availability

Academic Institutions and Nonprofits only
Human Genome-Wide Reduced Double-gRNA library

Pooled Library

#137999

Purpose

This gRNA library targets the human coding genome, aimed to reduce the scale of genome-wide perturbation screens up to fivefold compared to conventional methods, without sacrificing performance.

Depositor

Leopold Parts

Article

Peets et al bioRxiv 859652

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Oct. 15, 2020

Availability

Academic Institutions and Nonprofits only
Mouse metabolism knockout library

Pooled Library

#160129

Purpose

CRISPR library targets mouse metabolic genes

Depositor

Kivanc Birsoy

Article

Zhu et al Cell Metab. 2020 Oct 28. pii: S1550-4131

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Nov. 10, 2020

Availability

Academic Institutions and Nonprofits only
DNA repair library with 1,573 sgRNAs

Pooled Library

#177663

Purpose

CRISPR-interference (CRISPRi) library of 1,573 sgRNAs targeting 476 genes encoding factors involved in DNA repair and associated processes

Depositor

Brittany Adamson

Article

Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

Species

Homo sapiens

Use

CRISPR

Available since

July 11, 2023

Availability

Academic Institutions and Nonprofits only
Perturb-seq GBC library

Pooled Library

#85968

Purpose

Perturb-seq GBC library

Depositor

Jonathan Weissman

Article

Adamson et al Cell. 2016 Dec 15;167(7):1867-1882.e21.

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 14, 2017

Availability

Academic Institutions and Nonprofits only
Pan-Druggable Cancer Library

Pooled Library

#182133

Purpose

All-in-one CRISPR/Cas system with 74 individual elements. 63 elements target cancer-related genes with FDA-approved drug treatments, and 3 elements target key medulloblastoma driver genes.

Depositor

Prashant Mali

Article

Hu et al Biomaterials. 2022 Jan;280:121276. doi:

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Aug. 26, 2022

Availability

Academic Institutions and Nonprofits only
DNA repair library with 336 sgRNAs

Pooled Library

#177664

Purpose

CRISPR-interference (CRISPRi) library of 366 sgRNAs targeting 118 genes encoding factors involved in DNA repair and associated processes

Depositor

Brittany Adamson

Article

Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

Species

Homo sapiens

Use

CRISPR

Available since

Nov. 29, 2023

Availability

Academic Institutions and Nonprofits only

Showing: 161 - 180 of 275 results

Results per page:

Sort results by:

psgRNA Library

psgRNA_EcoWG1

Drosophila_sgRNA_group_3

Drosophila_sgRNA_group_1

Drosophila_sgRNA_group_2

Mouse Metabolism Library

Human Lentiviral sgRNA Library - Kinases

Human Lentiviral sgRNA Library - Nuclear

Human Lentiviral sgRNA Library - Cell Cycle

Human Lentiviral sgRNA Library - Control

Human Lentiviral sgRNA Library - Ribosomal Proteins

Human Lentiviral sgRNA Library - Unknown Function

pRG01-MCAP_MET

Human Transporter Knockout library

Human Genome-Wide Reduced Double-gRNA library

Mouse metabolism knockout library

DNA repair library with 1,573 sgRNAs

Perturb-seq GBC library

Pan-Druggable Cancer Library

DNA repair library with 336 sgRNAs

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