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Showing: 1 - 20 of 86 results

  6. Pan-Druggable Cancer Library

    Pooled Library
    #182133
    Purpose
    All-in-one CRISPR/Cas system with 74 individual elements. 63 elements target cancer-related genes with FDA-approved drug treatments, and 3 elements target key medulloblastoma driver genes.
    Depositor
    Prashant Mali
    Article
    Hu et al Biomaterials. 2022 Jan;280:121276. doi:
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    Aug. 26, 2022
    Availability
    Academic Institutions and Nonprofits only

  7. CHyMErA LbCas12a Nuclease Optimization hgRNA Library

    Pooled Library
    #209734
    Purpose
    CHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different LbCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.
    Depositor
    Thomas Gonatopoulos-Pournatzis
    Article
    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e
    Expression
    Mammalian
    Use
    CRISPR and Lentiviral
    Available since
    June 20, 2024
    Availability
    Academic Institutions and Nonprofits only

  8. CHyMErA AsCas12a Nuclease Optimization hgRNA Library

    Pooled Library
    #209735
    Purpose
    CHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different AsCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.
    Depositor
    Thomas Gonatopoulos-Pournatzis
    Article
    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e
    Expression
    Mammalian
    Use
    CRISPR and Lentiviral
    Available since
    June 20, 2024
    Availability
    Academic Institutions and Nonprofits only

  10. Human Genome-Wide Reduced Double-gRNA library

    Pooled Library
    #137999
    Purpose
    This gRNA library targets the human coding genome, aimed to reduce the scale of genome-wide perturbation screens up to fivefold compared to conventional methods, without sacrificing performance.
    Depositor
    Leopold Parts
    Article
    Peets et al bioRxiv 859652
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    Oct. 15, 2020
    Availability
    Academic Institutions and Nonprofits only

  11. Ma-PylRS-lib1

    Pooled Library
    #224585
    Purpose
    Pyrrolysine tRNA synthetase library to generate new genetic code expansion (GCE) systems for site-specific incorporation of non-canonical amino acids (ncAAs) into proteins.
    Depositor
    Ryan Mehl
    Article
    Avila-Crump et al ACS Chem Biol. 2022 Dec 16;17(12):3458-3
    Expression
    Bacterial
    Species
    Methanomethylophilus alvus
    Available since
    Jan. 6, 2025
    Availability
    Academic Institutions and Nonprofits only
Showing: 1 - 20 of 86 results