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pCAG-NLS-HA-Dre

Plasmid

#51272

Purpose

Component of the Co-Driver binary site-specific recombinase system, expression of the site-specific recombinase Dre (mouse codon-optimized)

Depositor

Pawel Pelczar

Publication

Hermann et al Nucleic Acids Res. 2014 Jan 9.

Insert

Dre

Tags

NLS-HA

Expression

Mammalian

Promoter

CAG

Available since

March 4, 2014

Availability

Academic Institutions and Nonprofits only

Cited by

5 Articles

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AAV phSyn1(S)-DreO-bGHpA

Plasmid

#50363

Purpose

Can be used to generate AAV virus that will express DreO recombinase in neurons from the synapsin promoter

Depositor

Hongkui Zeng

Publication

Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

Has service

AAV Retrograde and AAV5

Insert

DreO recombinase

Use

AAV

Tags

none

Mutation

Sequence optimized for expression in mammalian ce…

Promoter

hSyn1

Available since

Jan. 16, 2014

Availability

Academic Institutions and Nonprofits only

Cited by

2 Articles

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pAYP (pDre)

Plasmid

#62709

Purpose

Mammalian expression of Dre recombinase from the broadly active CAG promoter/enhancer

Depositor

Masato Ohtsuka

Publication

Miura et al PLoS One. 2015 Aug 18;10(8):e0135919. do

Insert

Dre

Expression

Mammalian

Promoter

CAG

Available since

Aug. 24, 2015

Availability

Academic Institutions and Nonprofits only

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pAAV-EF1a-mCherry-IRES-Dre

Plasmid

#55633

Purpose

Expresses Dre in Mammalian Cells

Depositor

Karl Deisseroth

Publication

Fenno et al Nat Methods. 2014 Jul;11(7):763-72. doi:

Inserts

mCherry
Dre

Use

AAV

Expression

Mammalian

Promoter

Ef1a and Ef1a/IRES

Available since

July 22, 2014

Availability

Academic Institutions and Nonprofits only

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hGFAP-NLS-HA-Dre-P2A-BFP

Plasmid

#51277

Purpose

Co-expression of the site-specific recombinase Dre and BFP under the control of the hGFAP promoter

Depositor

Pawel Pelczar

Publication

Hermann et al Nucleic Acids Res. 2014 Jan 9.

Insert

NLS-HA-Dre-P2A-BFP

Expression

Mammalian

Promoter

hGFAP

Available since

March 17, 2014

Availability

Academic Institutions and Nonprofits only

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FLAG-HA-DRE-1-pcDNA3.1-

Plasmid

#52513

Purpose

expresses C. elegans DRE-1 in mammalian cells with FLAG-HA tag at N-terminus

Depositor

Adam Antebi

Publication

Horn et al Dev Cell. 2014 Mar 4. pii: S1534-5807(14

Insert

Dre-1 (dre-1 Nematode)

Tags

FLAG-HA

Expression

Mammalian

Promoter

CMV

Available since

July 31, 2015

Availability

Academic Institutions and Nonprofits only

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pJFRC173-20XUAS-IVS-Dre::PEST

Plasmid

#32146

Purpose

Expresses Dre recombinase under control of 20XUAS sites in Drosophila

Depositor

Gerald Rubin

Publication

Nern et al Proc Natl Acad Sci U S A. 2011 Aug 9.

Insert

Dre::PEST

Expression

Insect

Promoter

Hsp70

Available since

Sept. 23, 2011

Availability

Academic Institutions and Nonprofits only

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RGS-6xHis-DRE-1-pcDNA3.1-

Plasmid

#52517

Purpose

expresses C. elegans DRE-1 in mammalian cells with RGS-6xHis tag at N-terminus

Depositor

Adam Antebi

Publication

Horn et al Dev Cell. 2014 Mar 4. pii: S1534-5807(14

Insert

Dre-1 (dre-1 Nematode)

Tags

RGS-6xHis

Expression

Mammalian

Promoter

CMV

Available since

July 31, 2015

Availability

Academic Institutions and Nonprofits only

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CMV-Dre-T2A-TagRFP

Plasmid

#167968

Purpose

Transient expression of Dre and TagRFP

Depositor

Emma Rawlins

Publication

Sun et al eLife. 2021 Oct 6;10. pii: 67886. doi: 1

Insert

Dre recombinase

Tags

TagRFP

Expression

Mammalian

Promoter

CMV

Available since

June 7, 2021

Availability

Academic Institutions and Nonprofits only

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pET-His-Dre

Plasmid

#123130

Purpose

Bacterial expression plasmid for wild-type Dre with an N-terminal His-tag.

Depositor

David Liu

Publication

Bessen et al Nat Commun. 2019 Apr 26;10(1):1937. doi:

Insert

Dre recombinase

Tags

6x His tag

Expression

Bacterial

Promoter

T7

Available since

April 26, 2019

Availability

Academic Institutions and Nonprofits only

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pCAGGS-pac-T2A-dre

Plasmid

#124833

Purpose

Puromycin resistance gene and dre recombinase

Depositor

Mario Capecchi

Insert

pac-T2A-dre

Expression

Mammalian

Promoter

CAG

Available since

June 19, 2019

Availability

Academic Institutions and Nonprofits only

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pCJ164

Plasmid

#175057

Purpose

rbcLXS7002 integrative plasmid expresses DRE recombinase as a translational fusion to rbcL

Depositor

David Nielsen

Publication

Jones et al ACS Synth Biol. 2021 Sep 17;10(9):2371-2

Insert

DRE

Use

Unspecified

Promoter

rbcLXS

Available since

Oct. 19, 2022

Availability

Academic Institutions and Nonprofits only

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T/brachyury(2A-Dre)

Plasmid

#140761

Purpose

Targeting vector to T/brachyury gene locus for induction of P2A-fused Dre, with PGK-EM7-puroR drug resistant cassette flanked by FRT(F3) sequence.

Depositor

Hideyuki Okano

Publication

Serizawa et al Development. 2019 Nov 4;146(21). pii: de

Insert

Dre

Use

Mouse Targeting

Promoter

Endogenous T/brachyury

Available since

June 16, 2020

Availability

Academic Institutions and Nonprofits only

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pBGX

Plasmid

#62666

Purpose

Donor vector for Dre knock-in via landing pad

Depositor

Masato Ohtsuka

Publication

Ohtsuka et al BMC Genomics. 2015 Apr 9;16:274. doi: 10

Insert

Dre

Use

Cre/Lox

Available since

Aug. 24, 2015

Availability

Academic Institutions and Nonprofits only

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pCAGGS-mTagBFP2-T2A-dre

Plasmid

#124832

Purpose

Monomeric TagBFP2 and dre recombinase

Depositor

Mario Capecchi

Insert

mTagBFP2-T2A-dre

Expression

Mammalian

Promoter

CAG

Available since

June 19, 2019

Availability

Academic Institutions and Nonprofits only

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pMEF2c-AHF-Dre-nls (JDW 35)

Plasmid

#242585

Purpose

The Mef2c anterior heart field promoter driving expression of Dre recombinase.

Depositor

Joshua Wythe

Publication

Gillespie WB et al Development. 2025 Nov 15;152(22):dev2043

Insert

DRE-nls

Expression

Mammalian

Promoter

mouse Mef2c

Available since

April 8, 2026

Availability

Academic Institutions and Nonprofits only

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pTalpha1-Dre

Plasmid

#133925

Purpose

Neuron-specific expression of Dre

Depositor

Frank Bradke, Sebastián Dupraz

Publication

Dupraz et al Curr Biol. 2019 Nov 18;29(22):3874-3886.

Insert

HA-Dre

Tags

HA

Expression

Mammalian

Promoter

CAG promoter

Available since

June 10, 2021

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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pCAGEN-Dre-nls (JDW 1131)

Plasmid

#229809

Purpose

A CAGGS-driven dre recombinase followed by a c-terminal 1x nls sequence

Depositor

Joshua Wythe

Publication

Gillespie WB et al Development. 2025 Nov 15;152(22):dev2043

Insert

DRE recombinase-nls

Tags

SV40 NLS

Expression

Mammalian

Promoter

CAG

Available since

Feb. 26, 2025

Availability

Academic Institutions and Nonprofits only

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Pvalb-2A-Dre Flp-in replacement vector

Plasmid

#61571

Purpose

Recombinase-mediated cassette exchange in ES cells to insert the Dre recombinase gene at the mouse Pvalb gene stop codon

Depositor

Hongkui Zeng

Publication

Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

Insert

Pvalb-2A-Dre (Pvalb Mouse, D6 Bacteriophage)

Use

Recombinase-mediated cassette exchange using flp …

Available since

Feb. 9, 2015

Availability

Academic Institutions and Nonprofits only

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pcDNA3 Flag beta-2-adrenergic-receptor

Plasmid

#14697

Depositor

Robert Lefkowitz

Publication

Tang et al Proc Natl Acad Sci U S A. 1999 Oct 26. 9

Insert

B2AR (ADRB2 Human)

Tags

Flag

Expression

Mammalian

Available since

June 19, 2007

Availability

Academic Institutions and Nonprofits only

Cited by

23 Articles

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