We narrowed to 173 results for: notch1

1. pDONR223_NOTCH1_ICN

   Plasmid

   #82087

   Purpose

   Gateway Donor vector containing NOTCH1 , part of the Target Accelerator Plasmid Collection.

   Depositor

   Jesse Boehm, David Root, William Hahn

   Article

   Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

   Insert

   NOTCH1 (NOTCH1 Human)
   

   Use

   Gateway entry vector

   Mutation

   ICN (AA1761-2556 present)

   Promoter

   None

   Available Since

   April 24, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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2. pYea5.1_Notch1_sfGFP

   Plasmid

   #207801

   Purpose

   Yeast 2µ vector for expression of Suc2SP-Notch1_100-sfGFP-GAL4

   Depositor

   Dieter Langosch

   Article

   Ortner et al J Mol Biol. 2023 Aug 1;435(18):168218. d

   Insert

   Suc2SP-Notch1_100-sfGFP-GAL4 fusion protein
   

   Tags

   Strep-TagII

   Expression

   Bacterial and Yeast

   Promoter

   TEF

   Available Since

   Nov. 20, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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3. pHR_PGK_SNIPR_hsNotch1 LNR

   Plasmid

   #188336

   Purpose

   Lentiviral vector - constitutive expression of an anti-CD19 SNIPR with a Notch1-ECD, a Notch1-TMD, a Notch1-JMD, and a Gal4VP64 transcriptional factor

   Depositor

   Kole Roybal

   Article

   Zhu et al Cell. 2022 Apr 14;185(8):1431-1443.e16.

   Insert

   PGK_antiCD19_Notch1-ECD_Notch1-TMD_Notch1-JMD_Gal4VP64
   

   Use

   Lentiviral

   Available Since

   March 9, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. Puro-iNotch1IC

   Plasmid

   #75338

   Purpose

   doxycycline inducible Notch1 intracellular domain gene over-expression

   Depositor

   Danwei Huangfu

   Article

   Zhu et al Cell Stem Cell. 2016 Apr 27. pii: S1934-

   Insert

   Notch1 Intracellular domain (Notch1 Mouse)
   

   Expression

   Mammalian

   Promoter

   TRE-tight

   Available Since

   May 24, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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5. pYea5.1_Notch1-L24_sfGFP

   Plasmid

   #207865

   Purpose

   Yeast 2µ vector for expression of Suc2SP-Notch1-L24_100-sfGFP-GAL4

   Depositor

   Dieter Langosch

   Article

   Ortner et al J Mol Biol. 2023 Aug 1;435(18):168218. d

   Insert

   Suc2SP-Notch1-L24_100-sfGFP-GAL4 fusion protein
   

   Tags

   Strep-TagII

   Expression

   Bacterial and Yeast

   Available Since

   Dec. 21, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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6. pBS mNotch1-IC (DM#270)

   Plasmid

   #15079

   Depositor

   Douglas Melton

   Article

   Murtaugh et al Proc Natl Acad Sci U S A. 2003 Dec 9. 10

   Insert

   Notch1-IC (Notch1 Mouse)
   

   Expression

   Bacterial

   Mutation

   K1750A

   Available Since

   Oct. 18, 2007

   Availability

   Academic Institutions and Nonprofits only

   

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7. anti-Notch1_E6-pBIOCAM5

   Plasmid

   #39344

   Depositor

   John McCafferty

   Article

   Falk et al Methods. 2012 Sep;58(1):69-78. doi: 10.1

   Insert

   scFv-Fc-fusion specific for Notch1 (clone B9) (Notch1, NOTCH1 Human, Mouse)
   

   Tags

   3xFLAG, 6xHis, and human Fc

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Oct. 30, 2013

   Availability

   Academic Institutions and Nonprofits only

   

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8. pCIneoRL-Notch1 3'UTR

   Plasmid

   #84595

   Purpose

   Renilla luciferase reporter containing NOTCH1 3' UTR

   Depositor

   Yanan Yang

   Article

   Zhang et al Nat Commun. 2016 Jul 26;7:12231. doi: 10

   Insert

   NOTCH1 3'UTR (NOTCH1 Human)
   

   Use

   Luciferase

   Tags

   Renilla Luciferase

   Promoter

   CMV

   Available Since

   Nov. 4, 2016

   Availability

   Academic Institutions and Nonprofits only

9. pHR_PGK_SNIPR_Notch1 del-NRR

   Plasmid

   #188353

   Purpose

   Lentiviral vector - constitutive expression of an anti-CD19 SNIPR with a Notch1-del-NRR-ECD, a Notch1-TMD, a Notch1-JMD, and a Gal4VP64 transcriptional factor

   Depositor

   Kole Roybal

   Article

   Zhu et al Cell. 2022 Apr 14;185(8):1431-1443.e16.

   Insert

   PGK_antiCD19_Notch1-NRRdeletion-ECD_Notch1-TMD_Notch1-JMD_Gal4VP64
   

   Use

   Lentiviral

   Available Since

   March 9, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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10. Lenti-sgNotch1#1/Cre

    Plasmid

    #193223

    Purpose

    Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Notch1 gene

    Depositor

    Julien Sage

    Article

    Lee et al Cell Rep. 2023 Jan 13;42(1):111990. doi:

    Insert

    sgNotch1#1 (Notch1 Mouse)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    Feb. 1, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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11. Lenti-sgNotch1#2/Cre

    Plasmid

    #193224

    Purpose

    Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Notch1 gene

    Depositor

    Julien Sage

    Article

    Lee et al Cell Rep. 2023 Jan 13;42(1):111990. doi:

    Insert

    sgNotch1#2 (Notch1 Mouse)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    Dec. 12, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pDONR223_NOTCH1_ICN

    Plasmid

    #82087

    Purpose

    Gateway Donor vector containing NOTCH1 , part of the Target Accelerator Plasmid Collection.

    Depositor

    David Root, William Hahn, Jesse Boehm

    Article

    Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

    Insert

    NOTCH1 (NOTCH1 Human)
    

    Use

    Gateway entry vector

    Mutation

    ICN (AA1761-2556 present)

    Promoter

    None

    Available Since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pLV sgRNA-Notch1 #1 GFP

    Plasmid

    #106950

    Purpose

    Lentivirus encoding sgRNA targeting murine Notch1. Includes GFP marker.

    Depositor

    Albert Edge

    Article

    Lenz et al Front Cell Dev Biol. 2019 Feb 19;7:14. d

    Insert

    gRNA targeting Notch1 (Notch1 Mouse)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Dec. 12, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pHR_PGK_SNIPR_hsNotch1 LNR, Notch2 JMD

    Plasmid

    #188374

    Purpose

    Lentiviral vector - constitutive expression of an anti-CD19 SNIPR with a Notch1-ECD, a Notch1-TMD, a Notch2-JMD, and a Gal4VP64 transcriptional factor

    Depositor

    Kole Roybal

    Article

    Zhu et al Cell. 2022 Apr 14;185(8):1431-1443.e16.

    Insert

    PGK_antiCD19_Notch1-ECD_Notch1-TMD_Notch2-JMD_Gal4VP64
    

    Use

    Lentiviral

    Available Since

    March 9, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. Notch1 intracellular domain-pcw107-V5

    Plasmid

    #64622

    Purpose

    when used to produce lentivirus, express physiological levels of insert

    Depositor

    Kris Wood, David Sabatini

    Article

    Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

    Insert

    NOTCH1 (NOTCH1 Human)
    

    Use

    Lentiviral

    Tags

    V5

    Mutation

    intracellular domain *

    Promoter

    PGK

    Available Since

    Nov. 30, 2015

    Availability

    Academic Institutions and Nonprofits only

16. pCS2 Notch1 ΔEMV-6MT

    Plasmid

    #41737

    Depositor

    Raphael Kopan, Jeffrey Nye

    Article

    Kopan et al Proc Natl Acad Sci U S A. 1996 Feb 20;93

    Insert

    Notch-1 Extracellular-domain-deleted construct (Notch1 Mouse)
    

    Tags

    6xMyc

    Expression

    Mammalian

    Mutation

    Contains murine Notch-1 protein fragment lacking …

    Available Since

    Jan. 28, 2013

    Availability

    Academic Institutions and Nonprofits only

    

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17. pCS2 Notch1 ICv-6MT

    Plasmid

    #41730

    Depositor

    Raphael Kopan

    Article

    Schroeter et al Nature. 1998 May 28;393(6683):382-6.

    Insert

    Notch-1 Intracellular Domain (Notch1 Mouse)
    

    Tags

    6xMyc

    Expression

    Mammalian

    Mutation

    Contains murine Notch-1 protein beginning at Vali…

    Available Since

    Dec. 19, 2012

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. Notch1 intracellular domain-pcw107

    Plasmid

    #64621

    Purpose

    when used to produce lentivirus, express physiological levels of insert

    Depositor

    Kris Wood, David Sabatini

    Article

    Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

    Insert

    NOTCH1 (NOTCH1 Human)
    

    Use

    Lentiviral

    Mutation

    intracellular domain *

    Promoter

    PGK

    Available Since

    May 12, 2015

    Availability

    Academic Institutions and Nonprofits only

19. pCS2 Notch1 LNG-6MT

    Plasmid

    #41738

    Depositor

    Raphael Kopan, Jeffrey Nye

    Article

    Kopan et al Proc Natl Acad Sci U S A. 1996 Feb 20;93

    Insert

    Notch-1 Lin-Notch-glp (LNG) repeat-containing construct (Notch1 Mouse)
    

    Tags

    6xMyc

    Expression

    Mammalian

    Mutation

    Contains murine Notch-1 leader peptide (aa 1-23) …

    Available Since

    Jan. 14, 2013

    Availability

    Academic Institutions and Nonprofits only

20. pCS2 Notch1 LNG (CC→SS)-6MT

    Plasmid

    #41739

    Depositor

    Raphael Kopan

    Article

    Mumm et al Mol Cell. 2000 Feb;5(2):197-206.

    Insert

    Notch-1 Lin-Notch-glp (LNG) repeat-containing construct, CC->SS (Notch1 Mouse)
    

    Tags

    6xMyc

    Expression

    Mammalian

    Mutation

    Contains murine Notch-1 leader peptide (aa 1-23) …

    Available Since

    Dec. 19, 2012

    Availability

    Academic Institutions and Nonprofits only